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  • EDMD
  • Emery-Dreifuss muscular dystrophy (EDMD), which affects young boys, causing contractures and weakness in the calves, weakness in the shoulders and upper arms, and problems in the way electrical impulses travel through the heart to make it beat (heart conduction defects). (encyclopedia.com)
  • Clinical
  • Professor Gorecki says: "If we can achieve improvement in the mouse model of Duchenne muscular dystrophy, then there is a good chance that the same treatment may work in human patients, though of course, it will still need to be tested in clinical trials. (port.ac.uk)
  • The exact mechanism through which increasing cGMP helps cardiac complications in Duchenne muscular dystrophy patients is not clear, but research is suggestive enough to have spurred a few clinical trials testing Viagra in these patients, says Joseph Beavo, a professor of pharmacology at the University of Washington and a co-author on the study. (go.com)
  • If clinical trials go well, cardiomyopathy due to Duchenne muscular dystrophy could become yet another off-label use for drug-maker Pfizer's popular ED drug. (go.com)
  • A tell-tale clinical characteristic for Duchenne muscular dystrophy (DMD) is Gowers' sign. (hopkinsmedicine.org)
  • [ 1 , 2 ] BMD is an inherited disease with a male distribution pattern and a clinical picture similar to that of Duchenne muscular dystrophy (DMD). (medscape.com)
  • Search
  • Update (March 24, 2015): A phase 1 trial of omigapil in children and adolescents 5-16 years old who have merosin-deficient congenital muscular dystrophy and meet other study criteria is open in Bethesda, Md. See Assessment of Safety and Tolerability of Omigapil (CALLISTO), or enter NCT01805024 in the search box at ClinicalTrials.gov. (mda.org)
  • world's
  • The team's success at manipulating P2X7 and their plans for further research have received strong endorsement from a panel of the world's leading experts in muscular dystrophy. (port.ac.uk)