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  • PATHWAY
  • Conclusions −These results suggest a novel 2-step pathway for increased tissue factor activity on smooth muscle cell surfaces in which lipoproteins regulate synthesis of a latent tissue factor and oxidants activate the protein complex. (ahajournals.org)
  • Therapeutics
  • P. J. Aschner and A. J. Ruiz, "Metabolic memory for vascular disease in diabetes," Diabetes Technology and Therapeutics , vol. 14, no. 1, pp. (hindawi.com)
  • Pathways
  • These new mineralocorticoid receptor-dependent signaling pathways suggest that glucocorticoids may contribute to vascular disease via mineralocorticoid receptor signaling, independent of circulating aldosterone. (ahajournals.org)
  • Metabolic
  • This book is organized into six chapters and begins with an introduction to the complexities of energy metabolism and how metabolic events can be correlated with a simultaneous quantitative assessment of smooth muscle mechanics and the contractile machinery at the molecular level. (elsevier.com)
  • Reference is made to the relation of possible anomalies in cellular or subcellular smooth muscle metabolic and/or ionic events to the bases of certain types of vascular disease. (elsevier.com)
  • Effects
  • We investigated the effects of corticosterone (10 −6 to 10 −12 mol/L) on early vascular mineralocorticoid receptor signaling by Western blotting, confocal microscopy, and myography. (ahajournals.org)
  • This study investigated the effects of methanolic extracts of leaves (LE), stems (SE), and roots (RE) of C. citratus and citral on vascular smooth muscle and explored their possible mechanisms of action. (hindawi.com)
  • In this study we report the comparative effects of methanolic extracts of various parts of the plant on vascular smooth muscle. (hindawi.com)
  • Physiol
  • Rembold, C. M. and Murphy, R. A., 1990, Latch-bridge model in smooth muscle: [Ca 2+ ] i can quantitatively predict stress, Am. J. Physiol . (springer.com)
  • mRNA
  • Smooth muscle alpha-actin mRNA was discernible 24 h after coarctation and was persistently expressed for up to 30 d. (jci.org)
  • Receptors
  • Other receptors in this family include the α- and β-adrenergic receptors, the muscarinic acetylcholine receptor, the various serotonin receptors, and important vascular receptors such as the thrombin, bradykinin, and endothelin receptors. (ahajournals.org)