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  • spasms
  • The aim of our study is to determine whether, similar to animal experiments, the 5HT1 receptors are responsible for sensory inhibition in spinal cord injured subjects, and whether activating these receptors (through the 5HT1 agonist Zolmitriptan) will restore the normal inhibition of sensory transmission that is lost after injury, thereby resulting in a decrease in the initiation of involuntary muscle spasms. (clinicaltrials.gov)
  • Severe
  • Within the framework of a prospective double-blind and randomized study evaluating the efficacy of continuous intrathecal baclofen therapy (CIBT) on paroxysmal dysautonomia (main objective) and hypertonia, recovery and tolerance (secondary objectives) during the initial recovery phase of severe head injury, continuous intrathecal baclofen infusion will be delivered. (clinicaltrials.gov)
  • groups
  • For each condition or site, information is provided on typical muscle pattern or muscle groups involved, dosing guidelines and dilution for the applicable toxins, number of injection sites, and potential risks and benefits. (springerpub.com)
  • passive
  • Physical therapy (PT) includes passive and active range of motion, facilitation of isolated muscle control, transitional movements, strengthening, transfer skills, and gait training. (clinicaltrials.gov)
  • Nerve
  • Some nerve and muscle disorders that start early in life (before age 25), like some forms of muscular dystrophy, can run in families. (clinicaltrials.gov)
  • Researchers want to learn more about genetic nerve and muscle disorders that start in childhood by studying affected people and their family members, as well as healthy volunteers. (clinicaltrials.gov)
  • To better understand nerve and muscle disorders that start early in life and run in families. (clinicaltrials.gov)
  • Healthy volunteers at least 4 weeks old with no nerve or muscle disorders. (clinicaltrials.gov)
  • Nerve and muscle electrical activity tests and biopsies. (clinicaltrials.gov)
  • Participants with nerve and muscle disorders will return to the Clinical Center every year. (clinicaltrials.gov)
  • Self-adhesive patches (electrodes) are placed on the skin close to the nerve that supplies the muscle and are connected by wires to a stimulator that produces the impulses. (clinicaltrials.gov)
  • Condition
  • Cervical dystonia is a condition in which the neck muscles contract involuntarily, causing the head to turn to one side, forward or backward. (clinicaltrials.gov)
  • test
  • After the walking test is completed, subjects' leg muscle strength is measured with a special device while they perform three activities. (clinicaltrials.gov)