Muscle fibers skeletal muscle. Medical search. Frequent questions

When measured in terms of strength per square centimeter, the female muscle can achieve the same force of contraction as that of a male. (medscape.com)
Applying a shock to skeletal muscle causes contraction. (medscape.com)
Through contraction, muscle provides motion of the body (skeletal muscle), motion of blood (cardiac muscle), and motion of hollow organs such as the uterus, esophagus, stomach, intestines, and bladder (smooth muscle). (medscape.com)
A large amount of body heat is produced by metabolism and by muscle contraction. (medscape.com)
Muscle contraction during shivering warms the body. (medscape.com)
The sarcoplasmic reticulum (smooth endoplasmic reticulum) stores calcium, which is released into the sarcoplasm during muscle contraction. (medscape.com)
Neuromuscular junctions, the sites where neurons contact muscle fibers to control their contraction, deteriorate during aging. (unibas.ch)
In terms of static strength and contraction speed, human muscle fibers kept pace with chimp muscles. (discovermagazine.com)
So, according to numerous studies, not only ACh (which by the way does not always lead to a contraction of the muscle fiber) is released in the vertebrate neuromuscular synapse, but also a number of other synaptically active molecules. (intechopen.com)
Skeletal muscles vary in their speeds of contraction. (msdmanuals.com)

Scholars@Duke publication: Nerve activity-dependent modulation of calcineurin signaling in adult fast and slow skeletal muscle fibers. (duke.edu)

The sciences are applied towards connective tissue of skeletal muscles fibers, blood vessels, nerve fibers to create structural integrity. (google.com)
Gross inspection of a skeletal muscle reveals collections of muscle fascicles surrounded by a layer connective tissue termed the epimysium. (medscape.com)
Each muscle fascicle represents a group of muscle fibers bound together by a layer of connective tissue termed the perimysium. (medscape.com)

Age impairs the ability of skeletal muscle to adapt to loading even in the absence of fiber degeneration. (cdc.gov)

Chronic HF feeding enhanced fat oxidation in oxidative and glycolytic muscles. (researcher-app.com)
Transcriptomic analysis reveals diverse expression patterns underlying the fiber diameter of oxidative and glycolytic skeletal muscles in steers. (cabi.org)

ERK1/2 signaling induces skeletal muscle slow fiber-type switching and" by Justin G. Boyer, Vikram Prasad et al. (lsu.edu)

The homozygous HIV-1 transgenic mouse line Tg26 reproduces the wasting syndrome of AIDS patients, thus constituting a valid animal model to characterize the muscle phenotype induced by HIV infection. (imrpress.com)
We take advantage of zebrafish models to address whether factors that regulate fiber-type differentiation enhance or suppress the zebrafish dmd muscle degeneration phenotype. (seattlechildrens.org)
Using mouse genetics, we observed that the muscle-specific expression of a constitutively active MEK1 mutant promotes greater ERK1/2 signaling that mediates fiber-type switching to a slow, oxidative phenotype with type I myosin heavy chain expression. (lsu.edu)

Neuromuscular junction (NMJ) is the functional contact (synapse) between an axon of motor neuron and muscle fiber. (intechopen.com)
It is generally accepted to consider this contact only as a specialized morpho-functional structure, where chemical transmission (via release of the acetylcholine (ACh)) of electrical signal from motor neuron to muscle fiber occurs, ultimately causing the muscle to contract. (intechopen.com)
A motor unit comprises a motor neuron in the spinal cord or brainstem together with the squad of muscle fibers it innervates. (medscape.com)

Targeted deletion of Kcne3 impairs skeletal muscle function in mice. (uni-bielefeld.de)
We examined whether cigarette smoke (CS) exposure and/or vitamin D deficiency impairs the skeletal muscle hypertrophic response to overload. (ljmu.ac.uk)

This paper provides a step-by-step protocol describing how to handle the tissue, conduct the imaging, and use stereological methods to obtain unbiased and quantitative data on fiber type-specific subcellular glycogen distribution in skeletal muscle. (jove.com)
Smooth muscle tissue is found in your skin, blood vessels and organs and along the tracts of the urinary, respiratory and reproductive systems. (oxygenmag.com)
Muscle tissue also helps maintain posture and produce heat. (medscape.com)
Fat and muscle are two different types of tissue, and one cannot be converted directly into the other, said Brad Schoenfeld, an assistant professor of exercise science at the City University of New York's Lehman College. (livescience.com)
Skeletal muscle is an inherently heterogenous tissue comprised primarily of myofibers, which are historically classified into three distinct fiber types in humans: one "slow" (type 1) and two "fast" (type 2A and type 2X), delineated by the expression of myosin heavy chain isoforms (MYHs). (researchgate.net)
In this work-package we explore mechanisms and pathways relevant to insulin resistance in various organs and tissues, such as liver, adipose tissue, kidney, skeletal muscle, heart, brain, inner ear. (lu.se)

This also suggests that the impact of potentially deleterious effects of ROS production on skeletal muscle metabolism/function under lipotoxic conditions is fiber type-specific. (researcher-app.com)
Myokines help muscles communicate with other organs and are known to have a beneficial impact on metabolism. (medicalnewstoday.com)
The causes of sarcopenia are diverse, ranging from altered muscle metabolism to changes in the nerves supplying muscles. (unibas.ch)
Our research interest is to understand how genetic variation influences skeletal muscle function and whole-body metabolism. (lu.se)

But humans do not produce the MyHC-M in these muscles. (johnhawks.net)
Humans tend to favor a type of muscle fiber called MHC I that allows for greater endurance and reduced energy consumption, but at the cost of raw strength. (discovermagazine.com)
We use translational approaches and regularly conduct focused intervention studies in humans, including skeletal muscle biopsies. (lu.se)

Accordingly, the volume of SR tubules localized around the myofibrils is strongly reduced in skeletal muscle fibers of 4- and 10-month-old sAnk1 knockout (KO) mice, while additional structural alterations only develop with aging. (mdpi.com)
Each fiber contains hundreds to thousands of rodlike myofibrils, which are bundles of thin and thick protein chains termed myofilaments. (medscape.com)

Human immunodeficiency virus (HIV)-induced wasting syndrome, characterized by weakness and severe loss of muscle mass, is a common condition of patients with advanced acquired immunodeficiency syndrome (AIDS). (imrpress.com)
Congenital muscular dystrophies are a group of genetic conditions that cause muscle weakness and wasting (atrophy) beginning very early in life. (medlineplus.gov)
In childhood, muscle weakness and joint deformities (contractures) restrict movement and interfere with the development of motor skills such as sitting, standing, and walking. (medlineplus.gov)
The damaged fibers weaken and die over time, leading to progressive weakness and atrophy of the skeletal muscles . (medlineplus.gov)
Researchers from the University of Basel's Biozentrum have demonstrated that a well-known drug can delay the progression of age-related muscle weakness. (unibas.ch)
Myasthenia gravis (MG) is a relatively rare acquired, autoimmune disorder caused by an antibody-mediated blockade of neuromuscular transmission resulting in skeletal muscle weakness and rapid muscle fatigue. (medscape.com)

To verify whether the lack of sAnk1 also alters intracellular Ca 2+ handling, cytosolic Ca 2+ levels were analyzed in stimulated skeletal muscle fibers from 4- and 10-month-old sAnk1 KO mice. (mdpi.com)
Diversification of intrinsic motoneuron electrical properties during normal development and botulinum toxin-induced muscle paralysis in early postnatal mice. (uni-bielefeld.de)
In this study, we identified a selective atrophy of fast-glycolytic myofibers in skeletal muscles of homozygous HIV-1 transgenic mice, whereas the more oxidative fiber types are spared. (imrpress.com)
In agreement with this, muscles enriched in fast-glycolytic myofibers such as the extensor digitorum longus and gastrocnemius, but not those rich in oxidative fibers such as the soleus, exhibited a reduced muscle size in homozygous HIV-1 transgenic mice compared to their littermate control counterparts. (imrpress.com)
Additionally, muscles of heterozygous HIV-1 transgenic mice displayed increased inflammation and blunted myofiber growth in an injury-induced muscle regeneration process. (imrpress.com)
Since no myogenic intrinsic defect was observed in satellite cells from the transgenic mice, these results support the notion of an inflammation-mediated, fiber-type-specific inhibition of muscle growth in the presence of the HIV-1 transgene. (imrpress.com)
Using a conditional and temporally regulated Cre strategy as well as Mapk1 (ERK2) and Mapk3 (ERK1) genetically targeted mice, MEK1-ERK2 signaling was shown to underlie this fast-to-slow fiber type switching in adult skeletal muscle as well as during development. (lsu.edu)
Physiologic assessment of these activated MEK1-ERK1/2 mice showed enhanced metabolic activity and oxygen consumption with greater muscle fatigue resistance. (lsu.edu)
The increase in plantaris muscle fiber cross-sectional area in response to overload was attenuated in vitamin D-deficient CS-exposed mice (smoking × diet interaction for hypertrophy, P = 0.03). (ljmu.ac.uk)
Here, we demonstrate that supraphysiological activation of TAK1 in skeletal muscle of adult mice stimulates translational machinery, protein synthesis, and myofiber growth. (genengnews.com)
Muscle size decreases at high age and is preserved by rapamycin treatment (from left to right: mouse muscle cross sections from adult, old and rapamycin treated old mice). (unibas.ch)
Contrary to our expectations, the long-term mTORC1 suppression with rapamycin is overwhelmingly beneficial for skeletal muscle aging in mice, preserving muscle size and strength," says Daniel Ham, first author of the study. (unibas.ch)

One focus of our lab is understanding the mechanisms behind how skeletal muscle cells differentiate into a specific muscle fiber type, either fast twitch or slow twitch. (seattlechildrens.org)

Commonly, muscle fatigue, i.e., the decline of the generable force level over time, is differentiated between central fatigue , i.e., the inability of the neural network to provide sufficient stimulation, and peripheral fatigue , i.e., the inability of the muscle cells to provide energy through metabolic activities (cf. (frontiersin.org)
In addition, PKC α and β2 were detected near or in the plasma membrane of muscle cells. (avma.org)
This study tested the hypothesis that calcineurin signaling is modulated in skeletal muscle cells by fluctuations in nerve-mediated activity. (duke.edu)
Electrical stimuli: Applying electrical stimuli between cardiac and smooth muscle cells causes the muscles to contract. (medscape.com)
Skeletal muscle consists of fibers (cells). (medscape.com)
Skeletal muscle is actually formed by the fusion of hundreds of embryonic cells. (medscape.com)
Skeletal Muscle Fibers (Cells) showing Striations, Teased apart-100X. (genengnews.com)
Shows: 6 skeletal muscle fibers (cells), striations and multinucleate cells. (genengnews.com)
Without functional α-dystroglycan to stabilize muscle cells, muscle fibers become damaged as they repeatedly contract and relax with use. (medlineplus.gov)
When this happens, your muscle cells shrink. (livescience.com)
We have previously demonstrated that a layer of skeletal muscle cells in the EOMs demonstrate a longitudinal variation in their myosin heavy chain (MyHC) isoforms. (upenn.edu)
Direct tests of muscle fibers actually found many similarities between our cells and theirs. (discovermagazine.com)
From the biopsies, muscle stem cells (satellite cells) are isolated and later used for preclinical measurements. (lu.se)
Our exercise studies include muscle biopsies and skeletal muscle satellite cells. (lu.se)

Vitamin D deficiency, which is highly prevalent in the general population, exerts similar deleterious effects on skeletal muscles to those induced by cigarette smoking. (ljmu.ac.uk)
Control of contractile protein synthesis in the extraocular muscles: Although oculomotor disorders such as strabismus or nystagmus can have marked, deleterious effects on the development of vision, little is known about the final common pathway of oculomotor control: the extraocular muscles (EOMs). (upenn.edu)

Objective -To investigate whether protein kinase C (PKC) isoforms are expressed in equine skeletal muscle and determine their distribution in various types of fibers by use of immunofluorescence microscopy. (avma.org)
Moreover, induction of MEK1-ERK1/2 signaling increased dystrophin and utrophin protein expression in a mouse model of limb-girdle muscle dystrophy and protected myofibers from damage. (lsu.edu)
The sarcoplasm of fiber is rich in glycogen (glucose polymer) granules and myoglobin (oxygen-storing protein). (medscape.com)
We demonstrate that supraphysiological activation of TAK1 in skeletal muscle stimulates translational machinery, protein synthesis, and myofiber growth," explained Ashok Kumar, the UH College of Pharmacy Else and Philip Hargrove endowed professor and chair, department of pharmacological and pharmaceutical sciences. (genengnews.com)
We have also identified a novel interplay between TAK1 and BMP (Bone Morphogenetic Protein) signaling pathway that promotes muscle growth," said Anirban Roy, PhD, research assistant professor of pharmacology at the University of Houston. (genengnews.com)
But to lose fat without also losing muscle, you have to eat the right foods: If you cut your calorie intake and don't eat enough protein, weight loss can result in a decrease in not only fat but also muscle. (livescience.com)
It's been shown over and over that low protein intake [while cutting calories] leads to an accelerated loss of muscle," Schoenfeld said. (livescience.com)
To make up for the lack of protein in the diet, the body burns not just stored fat but also muscle, which is made of protein. (livescience.com)
To prevent this from happening, Schoenfeld said he recommends that people who are trying to lose fat but not muscle consume about 0.8 grams of protein per pound of body weight per day. (livescience.com)
This is the amount of protein required for anyone lifting weights, Schoenfeld said, an activity that is essential for losing weight without also losing muscle. (livescience.com)
eat a sufficient amount of protein , and engage in resistance training (in which your muscles oppose a force), such as lifting weights , to tax the muscles and thus stimulate growth. (livescience.com)
The protein product of MYH16 is one of the heavy chain myosins, a kind of protein that works with actin to enable muscle fibers to contract. (johnhawks.net)
In most vertebrates this protein is expressed in muscles that develop from the first pharyngeal arch, including temporalis , which in mammals is the largest muscle of the jaw. (johnhawks.net)
Whey protein takes a bit of time in order to reach your muscle fibers. (bentham-open.org)
Protein is a good way to help build muscle, especially after a workout. (bentham-open.org)
Based on research, if you ever want to build muscle mass, it is important to eat as much protein relevant to your weight. (bentham-open.org)
Whey protein can help build your muscles. (bentham-open.org)

These findings suggest that SVCT2-mediated uptake of vitamin C could play diverse roles on skeletal muscle development and physiology. (nih.gov)
In women, the values of muscle strength, pulmonary ventilation, and cardiac output (all variables related with muscle mass) are generally 60-75% of the exercise physiology values recorded in men. (medscape.com)
Non-injurious stretch-shortening contractions: age effects on muscle physiology and morphology. (cdc.gov)
This summary discusses the basic anatomy of skeletal muscle, key features of skeletal muscle histology and physiology, and important presentations of muscular disease. (medscape.com)

Phospholipases can induce necrosis of skeletal muscle fibers. (wikipedia.org)

SVCT2 expression increases in cultures of both, slow and fast muscle-derived myoblasts, as they fuse to form mainly fast myotubes. (nih.gov)

Soleus, extensor digitorum longus (EDL), and epitrochlearis muscles were collected and mitochondrial H 2 O 2 (mtH 2 O 2 ) emission, palmitate oxidation, and gene expression and antioxidant system were measured. (researcher-app.com)

Neurotransmitters: Acetylcholine (ACh) stimulates skeletal muscle to contract. (medscape.com)
The autoimmune attack occurs when autoantibodies form against the nicotinic acetylcholine postsynaptic receptors at the neuromuscular junction of skeletal muscles (see the image below). (medscape.com)
[ 1 , 2 ] Although the chief target of the autoimmune attack in most cases is the skeletal muscle nicotinic acetylcholine receptor (nAChR), other antigenic targets that are components of the neuromuscular junction (NMJ) have also been implicated. (medscape.com)

Comparison of muscle fiber characteristics and meat quality between newborn and adult Haimen goats. (cabi.org)

Unlike the cardiac muscle or smooth muscle of the organs and digestive system, skeletal muscle can be willingly controlled. (howstuffworks.com)

We also establish that muscle activity must be sustained above native levels for calcineurin-dependent dephosphorylation of MEF2A and MEF2D to be transduced into an increase in MEF2 transcriptional function, suggesting that calcineurin cooperates with other activity-linked events to signal via these proteins. (duke.edu)
however, this muscle also showed an increase in the expression of antioxidant proteins, suggesting a higher capacity to generate and buffer ROS. (researcher-app.com)
Skeletal muscle fibers release proteins called myokines in the blood during physical activity. (medicalnewstoday.com)
These molecules that can suppress cancer cell growth include myokines, which are cytokines and other proteins secreted by the skeletal muscle fibers during physical activity. (medicalnewstoday.com)
Branched chain amino acids are found in the 35% of the muscle proteins. (bentham-open.org)

The quantitative metabolic responses of muscle fibers to exercise provide essential information for understanding and modifying the regulatory mechanisms of skeletal muscle. (unica.it)
We are investigating the mechanisms of skeletal muscle fiber-type differentiation. (seattlechildrens.org)
However, the role and mechanisms by which TAK1 regulates skeletal muscle mass remain less understood. (genengnews.com)

Their findings are published in the journal Nature Communications in a paper titled, " Supraphysiological activation of TAK1 promotes skeletal muscle growth and mitigates neurogenic atrophy . (genengnews.com)
TAK1 signalosome has been found to be activated in various conditions of muscle atrophy and hypertrophy. (genengnews.com)
The researchers are looking to investigate whether the activation of TAK1 using small molecules is sufficient to promote muscle growth and prevent atrophy in the elderly and various disease states. (genengnews.com)

Cardiac muscle is controlled by the heart's sinoatrial node and produces rhythmic contractions that cause your heart to pump. (oxygenmag.com)
Using genetic approaches, the researchers demonstrated that TAK1 is indispensable for maintaining healthy neuromuscular junctions, which are involved in transmitting nerve impulses to skeletal muscle and allowing muscle contractions. (genengnews.com)
Chimp and human muscles fundamentally work the same, they say, with filaments of actin sliding past thick myosin bands to produce contractions. (discovermagazine.com)
Experiments using stretch-shortening contractions (SSC) provide a model to investigate skeletal muscle adaptation in response to non-injurious contractions in old animals. (cdc.gov)

Small Ankyrins (sAnk1) are muscle-specific isoforms generated by the Ank1 gene that participate in the organization of the sarcoplasmic reticulum (SR) of striated muscles. (mdpi.com)

We show that dephosphorylation of NFATc1, MEF2A, and MEF2D transcription factors by calcineurin in all muscle types is dependent on nerve activity and positively correlated with muscle usage under normal weightbearing conditions. (duke.edu)
With increased nerve-mediated activity, calcineurin dephosphorylation of these targets was found to be potentiated in a way that paralleled the higher muscle activation profiles associated with functional overload or nerve electrical stimulation conditions. (duke.edu)
Finally, examination of individual fiber responses to overload and nerve electrical stimulation revealed that calcineurin-MEF2 signaling occurs in all fiber types but most readily in fibers that are normally least active (i.e. those expressing IIx and IIb myosin heavy chain (MHC)), suggesting that signaling via this phosphatase is also dependent upon the activation history of the muscle cell. (duke.edu)
Our findings demonstrate that targeted inactivation of TAK1 causes derangement of neuromuscular junctions and severe muscle wasting, very similar to muscle wasting observed during nerve damage, aging, and cancer cachexia. (genengnews.com)
And these molecules can be released from both nerve terminal (anterograde signal), and from muscle fiber (retrograde signal). (intechopen.com)
Only 60% of the axons in the nerve to a given muscle are motor to the muscle fibers that make up the bulk of the muscle. (medscape.com)
The nerve supply branches within the muscle belly, forming a plexus from which groups of axons emerge to supply the muscle fibers. (medscape.com)

Examples of skeletal circular muscles include the orbicularis oris and orbicularis oculi. (medscape.com)

Both cardiac and smooth muscles are involuntary, meaning you do not have conscious control over their actions. (oxygenmag.com)
Hormonal stimuli: Oxytocin stimulates smooth muscle in the uterus to contract during labor . (medscape.com)
Muscle fibers can broadly be divided into 3 muscles types: skeletal, cardiac, and smooth muscle. (medscape.com)
Two of these kinds-skeletal and smooth-are part of the musculoskeletal system. (msdmanuals.com)
Smooth muscles control certain bodily functions that are not readily under a person's control. (msdmanuals.com)
Smooth muscle surrounds many arteries and contracts to adjust blood flow. (msdmanuals.com)
Smooth muscle also is controlled by the brain but not voluntarily. (msdmanuals.com)
The triggers for contracting and relaxing smooth muscles are controlled by the body's needs, so smooth muscles are considered involuntary muscle because they operate without a person's conscious control. (msdmanuals.com)

Skeletal muscles consist of heterogeneous fibers with various contractile and metabolic properties that affect meat quality. (cabi.org)
It is at the level of the myofiber where the basic contractile element of muscle, the sarcomere, is found. (medscape.com)
Skeletal muscles are bundles of contractile fibers that are organized in a regular pattern, so that under a microscope they appear as stripes (hence, they are also called striped or striated muscles). (msdmanuals.com)

Distribution of PKC β1 was equal among the different fiber types. (avma.org)
Human skeletal muscles have different fiber types with distinct metabolic functions and physiological properties. (unica.it)

Since in vivo data from skeletal muscle during exercise is limited, a computational, physiologically based model has been developed to quantify the dynamic metabolic responses of many key chemical species. (unica.it)
An underlying hypothesis is that the recruitment and metabolic activation of the two main types of muscle fibers differ depending on the pre-exercise state and exercise protocols. (unica.it)
Here, activation measured by metabolic response (or enzymatic activation) in single fibers is considered linked but distinct from fiber recruitment characterized by the number (or mass) of each fiber type involved during a specific exercise. (unica.it)
Model simulations demonstrate that muscle-fiber recruitment and metabolic activation patterns in response to exercise produce significantly distinctive effects depending on the exercise conditions. (unica.it)
In summary, sustained MEK1-ERK1/2 activity in skeletal muscle produces a fast-to-slow fiber-type switch that protects from muscular dystrophy, suggesting a therapeutic approach to enhance the metabolic effectiveness of muscle and protect from dystrophic disease. (lsu.edu)
Once you have built your muscles, it is easier to control the body's metabolic rate. (bentham-open.org)

In vertebrate skeletal muscle, the vitamin C transporter SVCT2 is preferentially expressed in slow muscle fibers. (nih.gov)

Most of the skeletal muscular system is arranged into groups of agonists and antagonist muscles that work in concert to provide efficient and controlled motion. (medscape.com)

This project aims at the development of a fiber-based modeling approach for the behavior of muscles within the musculoskeletal system. (ecmiindmath.org)
Cardiac muscle forms the heart and is not part of the musculoskeletal system. (msdmanuals.com)

The axons supply single motor endplates placed about halfway along the muscle fibers. (medscape.com)

It also caused a significant reduction in mtH 2 O 2 emission in the EDL muscle, although a tendency towards a reduction was also found in the soleus and epitrochlearis muscles. (researcher-app.com)
The soleus muscle, despite being highly oxidative, elicited H 2 O 2 emission rates equivalent to only 20% and 35% of the values obtained for EDL and epitrochlearis muscles, respectively. (researcher-app.com)

Superficial and deeper muscles including tendons, vessels, nerves, and bone components of the left arm and shoulder. (unlv.edu)
Superficial and deeper muscles including tendons, vessels, nerves, and bone components of the left leg and foot. (unlv.edu)
In gross anatomy, the nerves to skeletal muscles are branches of mixed peripheral nerves. (medscape.com)

For some PKC isoforms, distribution was specific for fiber type. (avma.org)
Conclusions and Clinical Relevance -Results indicated that PKC isoforms are expressed in equine skeletal muscle in a fiber type-specific manner. (avma.org)

We conclude that KV3.4 expression in mouse skeletal muscle is regulated by the pattern of excitation. (uni-bielefeld.de)
Vullhorst D, Klocke R, Bartsch JW, Jockusch H. Expression of the potassium channel KV3.4 in mouse skeletal muscle parallels fiber type maturation and depends on excitation pattern. (uni-bielefeld.de)

Initiated by neural impulses and subsequent calcium release, skeletal muscle fibers contract (actively generate force) as a result of repetitive power strokes of acto-myosin cross-bridges. (frontiersin.org)
On the basis of bio-chemical kinetics, we present a model of muscle fiber exhaustion based on hydrolytic ATP-ADP-P i dynamics, which are assumed to be length- and calcium activity-dependent. (frontiersin.org)
Calcium currents in skeletal muscle fibers of an insect, Carausius morosus, inactivate under depolarization. (ox.ac.uk)

However, little is known about the temporal changes in muscle fiber characteristics and meat quality during. (cabi.org)
The temporalis muscle originates on the sides of the cranial vault, with its maximum extent marked either by a temporal line or by a sagittal crest. (johnhawks.net)
The muscle is accommodated by the temporal fossa, which is the space between the zygomatic arch and side of the vault. (johnhawks.net)
PURPOSE: To investigate the effect of a non-injurious SSC exposure on the temporal skeletal muscle response of young and old rodents. (cdc.gov)

Certain muscular dystrophies preferentially affect either fast or slow twitch muscle fibers. (seattlechildrens.org)

1990. Seasonal concentrations of cesium-137 in rumen content, skeletal muscles and feces of caribou from the porcupine herd: lichen ingestion rates and implications for human consumption. (cdc.gov)

This work will eventually help us understand why certain types of muscle fibers are more susceptible to muscular dystrophy. (seattlechildrens.org)
However, whether discrete fiber types exist or whether fiber. (researchgate.net)
The unusual properties of EOMs are defined by their diverse and unique fiber types. (upenn.edu)

This study investigated the effects of high-fat (HF) diet on parameters of oxidative stress among muscles with distinct fiber type composition and oxidative capacities. (researcher-app.com)
In conclusion, it appears that intrinsic differences related to the distribution of type I and type II fibers, rather than oxidative capacity, drove the activity of the anti- and pro-oxidant systems and determine ROS production in different skeletal muscles. (researcher-app.com)
This model distinguishes type I and II muscle fibers, which share the same blood supply. (unica.it)
The model incorporates species transport processes between blood and muscle fibers and most of the important reactions/pathways in cytosol and mitochondria within each fiber type. (unica.it)
We are using zebrafish and mouse models to study the functions of factors such as Pbx homeodomain transcription factors and how they control muscle fiber-type development. (seattlechildrens.org)
It is not clear how fiber-type identity confers susceptibility or resistance to muscular dystrophy. (seattlechildrens.org)
Recent studies, including work from our lab, now create an opportunity to directly test whether fiber-type modulation is a viable therapeutic approach for muscular dystrophies. (seattlechildrens.org)
Our approach is to manipulate fiber-type regulators that function early in development in dmd zebrafish embryos. (seattlechildrens.org)
We are also working to identify new epigenetic factors that regulate muscle fiber type. (seattlechildrens.org)
We expect that this project will identify genetic and epigenetic regulators of muscle fiber-type identities that confer susceptibility or resistance to muscular dystrophy. (seattlechildrens.org)
This project is aimed at an ultimate goal of manipulating skeletal muscle fiber type as a treatment for muscular dystrophy. (seattlechildrens.org)
Skeletal muscle is voluntary, meaning you can contract and extend it at will to run, jump, sit upright or type. (oxygenmag.com)
Where we differ, however, is in the type of fibers that together make up our skeletal muscles. (discovermagazine.com)
Skeletal muscle is what most people think of as muscle, the type that can be contracted to move the various parts of the body. (msdmanuals.com)

TAK1 regulates the activation of multiple signaling pathways in skeletal muscle. (genengnews.com)
Now, a mouse study by scientists from the University of Houston (UH) demonstrates how TAK1 regulates skeletal muscle mass. (genengnews.com)

Model simulations describe the dynamics of intracellular species concentrations and fluxes in muscle fibers during moderate intensity exercise according to various experimental protocols and conditions. (unica.it)
Skeletal muscle gets the lion's share of attention and is your main focus when it comes to exercise. (oxygenmag.com)
Maximal exercise capacity, whole body strength, in situ plantaris muscle force, and key markers of hypertrophic signaling (Akt, 4EBP1, and FoxO1) were not significantly affected by smoking or diet. (ljmu.ac.uk)
This study is the first to examine skeletal muscle-secreted molecules (myokines) in patients with metastatic castrate-resistant prostate cancer (mCRPC).This work supports an acute myokine response to exercise in patients with advanced cancer and that the serum of these patients after acute exercise has a growth-suppressive effect. (medicalnewstoday.com)
One of the implications of the study is that all people with cancer should try to complete a bout of high intensity exercise most if not every day of the week to dose their body with the anticancer factors produced by their skeletal muscles," he told us. (medicalnewstoday.com)
While aerobic exercise is generally healthy, it's not good for building muscle, at least not beyond the very early stages of working out, Schoenfeld said. (livescience.com)
During aerobic exercise, however, there's a limit to how much a person can tax his or her muscles, and it's not enough to make the muscles bigger, he said. (livescience.com)
So, as people get older, if they exercise less and continue to eat the same amount, or eat more, then they will also gain fat as they lose muscle. (livescience.com)
Strenuous and unaccustomed exercise frequently lead to what has been coined "delayed onset muscle soreness" (DOMS). (mdpi.com)
Endurance exercise induced fatigue factors such as a decrease in blood glucose, an increase in blood lactate, and the depletion of muscle glycogen, but those parameters recovered to basal levels within 6 h after exercise. (frontiersin.org)
The size and strength of skeletal muscles are maintained or increased by regular exercise. (msdmanuals.com)

Our findings on the age of the inactivating mutation in the MYH16 gene raise the intriguing possibility that the decrement in masticatory muscle size removed an evolutionary constraint on encephalization, as suggested by the anatomy of the muscle attachments relative to the sutures. (johnhawks.net)

The branches enter the muscles about one third of the way along their length, at motor points. (medscape.com)

The delayed rectifier potassium conductance in the sarcolemma and the transverse tubular system membranes of mammalian skeletal muscle fibers. (uni-bielefeld.de)

Each contains sarcoplasm (cytoplasm) and multiple peripheral nuclei per fiber. (medscape.com)

In the last sentence of their discussion, Stedman and colleagues advanced a provocative hypothesis: Not only did Homo have smaller jaws and teeth, but reducing the jaw muscles may have enabled the evolution of larger brain size. (johnhawks.net)

In skeletal muscles, α-dystroglycan helps stabilize and protect muscle fibers. (medlineplus.gov)

The left and right tibialis anterior muscles (LTA & RTA) were excised and weighed. (cdc.gov)

The regeneration of skeletal muscle fibers following injury: a review. (bvsalud.org)

The figure shows a snapshot of this simulation with the biceps and triceps muscles. (ecmiindmath.org)
Cylindrical muscles typically have greater mass at the center of the muscle, leading to a central body or muscle belly (eg, biceps brachii). (medscape.com)
For example, muscles that bend the elbow (biceps) are countered by muscles that straighten it (triceps). (msdmanuals.com)

As your muscles get stronger, your muscle fibers get bigger in a process called hypertrophy. (livescience.com)

Stable neuromuscular junctions are paramount to maintaining healthy muscles during aging and rapamycin effectively stabilizes them. (unibas.ch)

Anatomy58

Organisms23

Diseases22

Chemicals and Drugs70

Analytical, Diagnostic and Therapeutic Techniques and Equipment23

Phenomena and Processes57

Disciplines and Occupations4

Anthropology, Education, Sociology and Social Phenomena5

Technology, Industry, Agriculture2

Information Science3

Health Care3

Contraction10

Slow skeletal muscle fibers1

Connective tissue3

Ability of skeletal muscle1

Oxidative and glycolytic2

Induces1

Phenotype3

Motor neuron3

Impairs2

Tissue6

Metabolism4

Humans3

Myofibrils2

Weakness6

Mice12

Fast-twitch1

Cells14

Deleterious effects2

Protein17

Physiology4

Necrosis1

Myoblasts1

Extensor digito1

Acetylcholine3

Adult1

Organs1

Proteins5

Mechanisms3

Atrophy3

Contractions4

Sarcoplasmic reticulum1

Nerve7

Orbicularis oris1

Smooth8

Contractile3

Different fiber types2

Metabolic6

Vertebrate1

Muscular system1

Musculoskeletal2

Axons1

Soleus2

Nerves3

Isoforms2

Excitation2

Calcium3

Temporal4

Preferentially1

Feces1

Types3

Type14

Regulates2

Exercise11

Anatomy1

Enter the muscles1

Transverse1

Peripheral1

Stedman1

Stabilize1

Tibialis anterior1

Regeneration1

Biceps3

Hypertrophy1

Neuromuscular junctions1