Itraconazole (ITZ) is a triazole anti-fungal treatment widely used in the prevention and systemic treatment of a broad range of fungal infections, including aspergillosis , blastomycosis , candidiasis , histoplasmosis , and in some dermatological and nail infections. (ecancer.org)
Spores2
Outbreaks of histoplasmosis: The spores set sail. (uc.edu)
Histoplasmosis fungus grows beneath bird roosts but it can't form spores because of the acidic conditions in fresh droppings. (crittercontrolwichita.com)
Fungal infections1
Patients with histoplasmosis or other invasive fungal infections may present with disseminated, rather than localized, disease. (rxlist.com)
Monoclonal1
Infliximab-abda, the active ingredient in RENFLEXIS, is a chimeric IgG1τ monoclonal antibody (composed of human constant and murine variable regions) specific for human tumor necrosis factor -alpha (TNFα). (rxlist.com)
Infection model1
Administration of mAb's before Hc infection reduced fungal burden, decreased pulmonary inflammation, and prolonged survival in a murine infection model. (johnshopkins.edu)
Fungus1
This study establishes that mAb's to a cell surface protein of Hc alter the intracellular fate of the fungus and mediate protection in a murine model of lethal histoplasmosis, and it suggests a new candidate antigen for vaccine development. (johnshopkins.edu)
Antigen1
Antigen and antibody testing for histoplasmosis may be negative in some patients with active infection. (rxlist.com)
Human3
The calcium\binding site classically required for carbohydrate binding in C\type lectins is usually absent in human CD23 but is present in the murine molecule. (treatmentforprostatecancer.info)
To determine whether the absence of this calcium\binding site affects the structure and function of human CD23, CD23 mutant proteins with increasingly murine\like sequences were generated. (treatmentforprostatecancer.info)
This study offers insights into the evolutionary differences between murine and human CD23 and some of the functional differences between CD23 in different species. (treatmentforprostatecancer.info)
Model1
Furthermore, the vps4Δ null mutant has been shown to be markedly hypovirulent in a murine model. (medscape.com)
Histoplasma3
Histoplasma capsulatum is the causative agent of histoplasmosis, a systemic disease responsible for most reported causes of morbidity and mortality among immunosuppressed individuals. (bvsalud.org)
Updated a fact sheet on protecting workers from histoplasmosis , an infection caused by the Histoplasma fungus, which is often present in agricultural and construction environments. (cdc.gov)
Coccidioidomycosis2
We describe the epidemiology of 1,392 microbiology laboratory-confirmed cases of blastomycosis, histoplasmosis, and coccidioidomycosis in Ontario during 1990-2015. (nih.gov)
incidence of 0.41 cases/100,000 population), followed by histoplasmosis (211 cases) and coccidioidomycosis (89 cases). (nih.gov)
Equine histoplasmosis commonly known as epizootic lymphangitis (EL) is a neglected granulomatous disease of equine that is endemic to Ethiopia. (bvsalud.org)
Infection1
In murine models of tuberculosis infection, mice deficient in either TNF or in the p55 TNF receptor fail to recruit inflammatory cells to sites of infection, and fail to form functional granulomas. (medscape.com)
Macrophage1
Bioavailability of beryllium oxide particles: an in vitro study in the murine J774A.1 macrophage cell line model. (cdc.gov)
Blastomycosis2
This retrospective study substantially increases the number of known endemic fungal infections reported in Canada, confirms Ontario as an important region of endemicity for blastomycosis and histoplasmosis, and provides an epidemiologic baseline for future disease surveillance. (nih.gov)
Clinicians should include blastomycosis and histoplasmosis in the differential diagnosis of antibiotic-refractory pneumonia in patients traveling to or residing in Ontario. (nih.gov)
Workers1
Two outbreaks of occupationally acquired histoplasmosis: more than workers at risk. (cdc.gov)
Study1
This study highlights the possible origins and transmission routes of Histoplasmosis in Ethiopia. (bvsalud.org)