Multisubunit e3 ubiquitin ligase. Medical search. Frequent questions

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Anatomy19

HeLa Cells Cell Line HEK293 Cells Cell Line, Tumor Cell Nucleus Endoplasmic Reticulum COS Cells Cells, Cultured Cytoplasm Chromatin Endosomes Fibroblasts Lysosomes NIH 3T3 Cells Vacuoles Cell Membrane Mitochondria Golgi Apparatus Inclusion Bodies

Organisms11

Saccharomyces cerevisiae Cercopithecus aethiops Arabidopsis Mice, Knockout Escherichia coli Schizosaccharomyces Yeasts Drosophila melanogaster Drosophila Mice, Inbred C57BL Caenorhabditis elegans

Diseases4

Angelman Syndrome Lafora Disease Muscular Atrophy Genomic Instability

Chemicals and Drugs127

Ubiquitin-Protein Ligases Ubiquitin-Protein Ligase Complexes Ubiquitin Anaphase-Promoting Complex-Cyclosome Cullin Proteins SKP Cullin F-Box Protein Ligases Ubiquitins Proteasome Endopeptidase Complex F-Box Proteins Ubiquitin-Conjugating Enzymes Ligases Ubiquitin Thiolesterase RNA Ligase (ATP)Polyubiquitin Endosomal Sorting Complexes Required for Transport S-Phase Kinase-Associated Proteins Proto-Oncogene Proteins c-cbl beta-Transducin Repeat-Containing Proteins Saccharomyces cerevisiae Proteins Cell Cycle Proteins Multiprotein Complexes DNA Ligases Protein Subunits Carrier Proteins Nuclear Proteins DNA-Binding Proteins Transcription Factors Ubiquitin-Activating Enzymes Proto-Oncogene Proteins c-mdm2 Multienzyme Complexes Polynucleotide Ligases Cysteine Endopeptidases Recombinant Fusion Proteins Receptors, Autocrine Motility Factor Lysine Repressor Proteins RNA, Small Interfering Ubiquitin C Proteasome Inhibitors Adaptor Proteins, Signal Transducing Macromolecular Substances Membrane Proteins Leupeptins Recombinant Proteins SUMO-1 Protein Von Hippel-Lindau Tumor Suppressor Protein Peptide Synthases Fungal Proteins Ubiquitin-Specific Proteases Proteins Tumor Suppressor Proteins Endopeptidases Small Ubiquitin-Related Modifier Proteins Peptide Hydrolases Ubiquitinated Proteins Glutamate-Cysteine Ligase Cdc20 Proteins Tumor Suppressor Protein p53 Apc11 Subunit, Anaphase-Promoting Complex-Cyclosome Adenosine Triphosphatases Arabidopsis Proteins Mutant Proteins Intracellular Signaling Peptides and Proteins Drosophila Proteins Vacuolar Proton-Translocating ATPases Cdh1 Proteins Histones Molecular Chaperones Schizosaccharomyces pombe Proteins Chromosomal Proteins, Non-Histone Protein-Serine-Threonine Kinases RNA, Messenger Proliferating Cell Nuclear Antigen Cyclin-Dependent Kinase Inhibitor Proteins Apc5 Subunit, Anaphase-Promoting Complex-Cyclosome Fanconi Anemia Complementation Group L Protein DNA Primers Cyclin-Dependent Kinase Inhibitor p27 Vesicular Transport Proteins Green Fluorescent Proteins DNA BRCA1 Protein Trans-Activators DNA, Complementary Immediate-Early Proteins Chromatin Protein Inhibitors of Activated STAT DNA-Directed RNA Polymerases HSC70 Heat-Shock Proteins Carbon-Nitrogen Lyases TNF Receptor-Associated Factor 6 RNA Polymerase II Adenovirus E4 Proteins Cysteine Proteinase Inhibitors Adenosine Triphosphate Cyclin E Proto-Oncogene Proteins DNA Helicases Protein Kinases Nerve Tissue Proteins Casein Kinase I vif Gene Products, Human Immunodeficiency Virus Histone Acetyltransferases Glutathione Transferase Caenorhabditis elegans Proteins Transcription Factor TFIID Peptides Viral Proteins Plant Proteins Apc2 Subunit, Anaphase-Promoting Complex-Cyclosome Smad7 Protein Mediator Complex Securin Suppressor of Cytokine Signaling Proteins Apc1 Subunit, Anaphase-Promoting Complex-Cyclosome Cyclin B HSP70 Heat-Shock Proteins Oncogene Protein v-cbl Protein Tyrosine Phosphatases, Non-Receptor Muscle Proteins Gene Products, vif Bacterial Proteins I-kappa B Kinase Protein Isoforms NF-kappa B Apc7 Subunit, Anaphase-Promoting Complex-Cyclosome Hypoxia-Inducible Factor 1, alpha Subunit

Analytical, Diagnostic and Therapeutic Techniques and Equipment23

Two-Hybrid System Techniques Immunoprecipitation Models, Molecular Models, Biological Transfection Sequence Alignment Immunoblotting Blotting, Western Cloning, Molecular Protein Interaction Mapping Crystallography, X-Ray Precipitin Tests Ligase Chain Reaction Gene Knockdown Techniques Mutagenesis, Site-Directed Electrophoresis, Polyacrylamide Gel Microscopy, Fluorescence Amino Acid Substitution Mass Spectrometry Genetic Complementation Test Chromatography, Affinity Reverse Transcriptase Polymerase Chain Reaction Enzyme Stability

Phenomena and Processes72

Ubiquitination RING Finger Domains Protein Binding Proteolysis Amino Acid Sequence Protein Structure, Tertiary Mutation Amino Acid Motifs Protein Processing, Post-Translational Sequence Homology, Amino Acid Protein Stability Signal Transduction Substrate Specificity Protein Transport RNA Interference Binding Sites Base Sequence Phosphorylation Transfection Sumoylation Transcription, Genetic Cell Cycle Protein Interaction Domains and Motifs DNA Damage Gene Expression Regulation Mitosis Protein Conformation DNA Repair Down-Regulation Protein Folding Conserved Sequence Plasmids F-Box Motifs Endoplasmic Reticulum-Associated Degradation Gene Deletion Catalysis Phenotype Catalytic Domain Zinc Fingers Endocytosis Dimerization Protein Multimerization Kinetics Protein Structure, Quaternary DNA Replication Chromatin Amino Acid Substitution Mutagenesis Hydrolysis Gene Expression Regulation, Plant Protein Structure, Secondary Apoptosis Promoter Regions, Genetic Enzyme Activation Ultraviolet Rays Genes, Fungal Transcriptional Activation Mitochondrial Degradation Gene Expression Regulation, Fungal Gene Silencing S Phase Cell Proliferation Gene Expression Time Factors Genomic Instability Ankyrin Repeat Structure-Activity Relationship Active Transport, Cell Nucleus Gene Expression Regulation, Enzymologic Molecular Weight Enzyme Stability G1 Phase

Information Science3

Molecular Sequence Data Amino Acid Sequence Base Sequence

Health Care1

Ultraviolet Rays

Anatomy Organisms Diseases Chemicals and Drugs Analytical, Diagnostic and Therapeutic Techniques and Equipment Phenomena and Processes Information Science Health Care

Ubiquitin-Protein Ligases Ubiquitin-Protein Ligase Complexes Ubiquitin Anaphase-Promoting Complex-Cyclosome Ubiquitination Cullin Proteins SKP Cullin F-Box Protein Ligases Ubiquitins Proteasome Endopeptidase Complex F-Box Proteins Ubiquitin-Conjugating Enzymes Ligases Ubiquitin Thiolesterase RNA Ligase (ATP)RING Finger Domains Polyubiquitin Protein Binding Endosomal Sorting Complexes Required for Transport Molecular Sequence Data S-Phase Kinase-Associated Proteins Proteolysis Amino Acid Sequence Protein Structure, Tertiary Proto-Oncogene Proteins c-cbl beta-Transducin Repeat-Containing Proteins Saccharomyces cerevisiae Proteins Cell Cycle Proteins Mutation HeLa Cells Multiprotein Complexes Cell Line Saccharomyces cerevisiae DNA Ligases HEK293 Cells Protein Subunits Carrier Proteins Nuclear Proteins Amino Acid Motifs DNA-Binding Proteins Two-Hybrid System Techniques Immunoprecipitation Transcription Factors Protein Processing, Post-Translational Sequence Homology, Amino Acid Protein Stability Ubiquitin-Activating Enzymes Proto-Oncogene Proteins c-mdm2 Multienzyme Complexes Signal Transduction Substrate Specificity Protein Transport Polynucleotide Ligases Cysteine Endopeptidases Recombinant Fusion Proteins Receptors, Autocrine Motility Factor RNA Interference Models, Molecular Lysine Repressor Proteins Models, Biological Binding Sites RNA, Small Interfering Base Sequence Phosphorylation Ubiquitin C Transfection Proteasome Inhibitors Sumoylation Adaptor Proteins, Signal Transducing Sequence Alignment Immunoblotting Macromolecular Substances Membrane Proteins Leupeptins Transcription, Genetic Recombinant Proteins SUMO-1 Protein Cell Line, Tumor Von Hippel-Lindau Tumor Suppressor Protein Cell Cycle Peptide Synthases Fungal Proteins Ubiquitin-Specific Proteases Proteins Tumor Suppressor Proteins Endopeptidases Protein Interaction Domains and Motifs Small Ubiquitin-Related Modifier Proteins Cell Nucleus Peptide Hydrolases Ubiquitinated Proteins Glutamate-Cysteine Ligase DNA Damage Blotting, Western Cdc20 Proteins Tumor Suppressor Protein p53 Gene Expression Regulation Apc11 Subunit, Anaphase-Promoting Complex-Cyclosome Mitosis Endoplasmic Reticulum

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