Finite elementModelingBiochemicalSimulationsComputationalMechanicalMathematicalStructuralBoneBehaviorBiologicalStructuresImplantEngineeringAdaptiveBiologyPropertiesAimsGroupDisordersDesignWorkEnvironmentModelsFrameworkFiniteSimulationBiomechanics2019ApproachesMechanicalTissueBehaviorParametersStiffnessMolecularShearInsightInterpretationApproachModelStrainMedical devicesFunctionComplex
Finite element4
- We devise a strategy to couple the discrete biological model at the molecular /cellular level and the biomechanical finite element simulations at the tissue level. (upf.edu)
- The biomechanical behaviour of each intermediate TMJ design was assessed under four different nominal and maximum biting tasks using finite element analyses. (zju.edu.cn)
- and, (ii) hyperlipidemia affects collagen orientation and μCT volumetric tissue mineral density (vTMD) in murine cortical bone, we have constructed the first multiscale finite element (mFE), mouse-specific femoral model to study the effect of collagen orientation and vTMD on strength in Ldlr(-/-), a mouse model of hyperlipidemia, and its control wild type, on either high fat diet or normal diet. (activelifescientific.com)
- In addition, our group has developed multiscale finite element modeling techniques to predict hysteresis friction based on shoe and floor roughness, shoe material properties and the geometry of tread. (cdc.gov)
Modeling8
- Multiscale computational modeling of single cell migration in 3D. (esbiomech.org)
- The Casa Matemática Oaxaca (CMO) will host the "Multiscale Modeling of Plant Growth, Pattern Formation and Actuation" workshop in Oaxaca, from October 16 to October 21, 2022. (birs.ca)
- The workshop is focused at the intersection of three areas: molecular signaling (hormonal control and exchange of signaling molecules), network modeling (mathematical representation of biological feedback mechanisms), and biomechanical concepts (physical and mechanical analysis of force driven deformation or cells and tissues). (birs.ca)
- Candidate objective measures may be based on minimally invasive imaging technologies, electrophysiological recordings, integration of multiparametric imaging and electrophysiology approaches, or their integration with other markers (e.g. , immune factors, genomic markers, physiological factors) through multiscale modeling or machine learning analysis. (nih.gov)
- Multiscale and multiphysics modeling. (usnccm.org)
- Abstract: Bone Bioengineering Laboratory is developing innovative technology in microstructural assessments, biomechanical modeling, multiscale and mechanobiological approaches in skeletal research. (ou.edu)
- EU H2020 Project 'BONEIMPLANT (Monitoring bone healing around endosseous implants: from multiscale modeling. (fabiodisconzi.com)
- We propose that multiscale mathematical pathway modeling can be used to decrease time required to bring candidate drugs to clinical trial and increase the probability that they will be successful in humans. (cytosolve.com)
Biochemical3
- Programming induced pluripotent stem cells into heart muscle cells requires biochemical and biomechanical cues. (medgadget.com)
- We are using biochemical and biomechanical cues to enhance the differentiation and maturation. (medgadget.com)
- In 2008 she took up a Junior Research Fellowship at Christ Church College, Oxford, to develop mathematical models that describe biomechanical and biochemical stimulation of tissues. (ox.ac.uk)
Simulations2
- Innovations in numerical techniques (FEM/FVM/BEM/FDM/Meshless methods etc) and algorithmic issues for biomechanical simulations. (usnccm.org)
- The PhD Studentship focuses on multiscale modelling and simulations for keloid disorders, as well as mathematical and statistical approaches for parameter identification using data generated by biological and bio-mechanical experiments. (frand.fr)
Computational2
- The Barocas research group explores the relationship between tissue architecture and mechanics using a combination of multiscale computational models and innovative mechanical experiments. (umn.edu)
- The interplay between fibril level degradation and the tissue-level aggregate response to biomechanical loading was explored in this work by a computational multiscale cartilaginous model. (elsevierpure.com)
Mechanical6
- Despite the dominant role of mass in bone mechanical properties, optimal clinical and societal management of osteoporosis requires a better understanding of the role of multiscale biophysical and biomechanical properties of the bone matrix in fracture incidence. (psi.ch)
- Alterations to ECM structural and mechanical properties due to mechanical loading and tissue healing may affect this multiscale strain transfer and stress transmission through the ECM. (nsf.gov)
- The "mechanical" phenotype necessitates the correction of biomechanical abnormalities, the use of hyaluronic acid containing agents, whereas the "enthesopathic" phenotype is treated with local therapy. (almclinmed.ru)
- In parallel to these developments, we will also discuss our multiscale mechanobiological approaches in understanding the mechanisms of how bone senses and responds to mechanical loading and showcase how mechanobiology links to bone microstructure and mechanics. (ou.edu)
- Subsequently I intend to pursue graduate school to earn a doctoral degree in Mechanical or Biomechanical Engineering. (purdue.edu)
- In May 2012, Professor Shipley took up her Lectureship (now Professorship) position within the Biomechanical Engineering Group at UCL Mechanical Engineering. (ox.ac.uk)
Mathematical1
- During her DPhil studies at St Hugh's working on multiscale mathematical models of blood flow and drug delivery in vascularised tissues, Professor Shipley developed a passion for interdisciplinary research around the application of mathematical models in medicine. (ox.ac.uk)
Structural4
- Multiscale structural gradients enhance the biomechanical functionality of the spider fang. (mpg.de)
- Structural optimization of patient-specific temporomandibular joint replacement implants for additive manufacturing: novel metrics for safety evaluation and biomechanical performance[J]. Journal of Zhejiang University Science D, 2022, 5(2): 333-347. (zju.edu.cn)
- Finally, structural optimisation allows for a volume reduction of up to 44% with a minimum loss of implant safety and biomechanical performance . (zju.edu.cn)
- It combines biomechanical testing with imaging to investigate the correlation between structural change and function of the myocardium. (umich.edu)
Bone5
- To improve bone strength prediction beyond limitations of assessment founded solely on the bone mineral component, we investigated the effect of hyperlipidemia, present in more than 40% of osteoporotic patients, on multiscale structure of murine bone. (activelifescientific.com)
- Failures are due to degraded bone remodeling at the bone-implant interface, a multiscale phenomenon of an interdisciplinary nature which remains poorly understood. (fabiodisconzi.com)
- The objective of BoneImplant is to provide a better understanding of the multiscale and multitime mechanisms at work at the bone-implant interface. (fabiodisconzi.com)
- To do so, BoneImplant aims at studying the evolution of the biomechanical properties of bone tissue around an implant during the remodeling process. (fabiodisconzi.com)
- A multimodality and multi-physical experimental approach will be carried out to assess the biomechanical properties of newly formed bone tissue as a function of the implant environment. (fabiodisconzi.com)
Behavior1
- The occurrence of these lesions is an bruxism change the magnitude, direction, frequency, increasingly common finding in dental clinical duration and localization of the occlusal contacts, practice with prevalence rates up to 85% in some which result in different biomechanical behavior in populations (QUE et al. (bvsalud.org)
Biological1
- The FE part simulates the biomechanical effects of repeated strain on the biological tissue. (upf.edu)
Structures1
- Cell-type specific and multiscale dynamics of human focal seizures in limbic structures. (medscape.com)
Implant1
- In addition, a new set of metrics were proposed to compare each design regarding biomechanical performance and implant safety . (zju.edu.cn)
Engineering2
- Selene Pirola (Department of BioMechanical Engineering) at Delft University of Technology. (academictransfer.com)
- At my home university, I have conducted research in biomechanical engineering on the subjects of fluid flow in porous media, and gait analysis. (purdue.edu)
Adaptive2
- Using state-of-the art biomechanical modelling, the "Adaptive, Multi-scale, Data-Infused Biomechanical Models for Cardiac Diagnostic and Prognostic Assessment" project will address these challenges by providing a modelling framework for assessment of the heart. (ukri.org)
- The Xu Research Group projects focus multiscale mechanics for functional material and device design - in particular, nanoporous materials, nanopore-functional liquid composite materials, bioinspired and biointegrated electronics and devices, soft-hard integration and adaptive soft materials. (virginia.edu)
Biology1
- The group has a well-equipped lab to perform multiscale biomechanical studies including commercial and custom-built AFMs coupled to inverted confocal microscopes, cell and molecular biology techniques and equipment to perform animal studies. (ibecbarcelona.eu)
Properties2
- Abstract Reference point indentation (RPI) has emerged as a novel tool to measure material-level biomechanical properties in vivo. (activelifescientific.com)
- The experimental approach aims at estimating the effective adhesion energy and the potentiality of quantitative ultrasound imaging to assess different biomechanical properties of the interface. (fabiodisconzi.com)
Aims1
- Uniting measurements from microscopy, rheology, and medical imaging, this project aims to create biomechanical models that provide detailed information on the structure and function of the heart aiding diagnosis. (ukri.org)
Group2
- This represents an increase of 15% in biomechanical performance for incisor biting, 15% for right molar biting, 17% for left molar biting and a decrease of 2% for left group biting compared with the initial design. (zju.edu.cn)
- Thus the project "Multiscale Determinants of Myocardial Mechanics" with David Nordsletten's group is the perfect fit. (umich.edu)
Disorders1
- She is generously sponsored by Stiftelsen Promobila (2019-23): Multiscale and multimodal biomechanical research for persons with motion disorders. (kth.se)
Design1
- (ii) SO5.2: Application of the DCoMEX framework to the multiscale material design. (ntua.gr)
Work1
- Together, this work identifies the multiscale response of tendon to dynamic loading and healing, and provides new insight into microenvironmental features that tenocytes may experience following injury and after cell delivery therapies. (nsf.gov)
Environment1
- The extracellular matrix (ECM) is the primary biomechanical environment that interacts with tendon cells (tenocytes). (nsf.gov)
Models1
- Biomechanical models will be systematically validated using animal heart models, providing rich data for understanding the biomechanics in vivo and ex vivo. (ukri.org)
Framework6
- Depending on the neuromechanical conditions, the muscle spindle model output appears to 'encode' aspects of muscle force, yank, length, stiffness, velocity, and/or acceleration, providing an extendable, multiscale, biophysical framework for understanding and predicting proprioceptive sensory signals in health and disease. (elifesciences.org)
- In this talk, a multiscale computational modeling framework for evaluating the fracture processes in bone at different length scales will be presented. (elsevier.com)
- By integrating atomistic simulations with a novel multiscale numerical framework, this work provides new biomolecular mechanistic perspectives through which many mechanosensitive cellular processes could be quantitatively characterised. (unl.edu)
- This approach is based on a multi-level biomechanical framework, where the biomechanical properties of eye tissues are derived from a single crimped A stress based remodeling approach is used to investigate the sensitivity of the collagen architecture in humane eye tissues on the biomechanical response of the lamina cribrosa with a particular focus on the stress environment of the nerve fibers. (uni-weimar.de)
- This approach is based on a multi-level biomechanical framework, where the biomechanical properties of eye tissues are derived from a single crimped fibril at the micro-scale via the collagen network of distributed fibrils at the meso-scale to the incompressible and anisotropic soft tissue at the macro-scale. (uni-weimar.de)
- 15. An adversarial machine learning framework and biomechanical model-guided approach for computing 3D lung tissue elasticity from end-expiration 3DCT. (nih.gov)
Finite2
- We developed a high-fidelity multiscale finite element model of the rat brain featuring a detailed definition of the angioarchitecture. (nature.com)
- His research has also developed multiscale finite element damage models for composite materials. (universityofgalway.ie)
Simulation3
- The successful candidate will have access to advanced biomechanical testing, imaging, and simulation capabilities and supervision by senior spine researchers at both institutions. (isbweb.org)
- We are seeking a Ph.D. student for the development of multiscale simulation methods to work in the recently funded excellence cluster at KIT. (findaphd.com)
- MD-Paedigree integrates methodological approaches from the targeted specialties and consequently analyzes biomedical data derived from a multiplicity of heterogeneous sources (from clinical, genetic and metagenomic analysis, to MRI and US image analytics, to haemodynamics, to real-time processing of musculoskeletal parameters and fibres biomechanical data, and others), as well as specialised biomechanical and imaging VPH simulation models. (uniroma1.it)
Biomechanics4
- The topics ranged from locomotion, human movement and multiscale biomechanics, to motor control and animal biomechanics. (vicon.com)
- Dr. Ted Vaughan's current research is focused on the development of multiscale computational models that facilitate a better understand of different aspects of bone biomechanics and mechanobiology. (universityofgalway.ie)
- A collection of novelties and research outcomes presented at the 9th National Biomechanics Congress (CNB 2021, 19-20 February, Porto, Portugal), this book reflects the enthusiasm and intense activity of the Portuguese biomechanical community, as well as the multidisciplinary character of the field. (youbookinc.com)
- The National Congress of Biomechanics (CNB) is a scientific meeting organized in Portugal under the auspices of the Portuguese Biomechanical Society (SPB). (youbookinc.com)
20191
- 2019 ) Yank: the time derivative of force is an important biomechanical variable in sensorimotor systems. (neurotree.org)
Approaches5
- Using dissipative particle dynamics (DPD) combined with coarse grained molecular dynamics (CGMD) approaches, we developed a multiscale deformable platelet model to accurately describe the molecular-scale intra-platelet constituents and biomechanical properties of platelets in blood flow. (nih.gov)
- Although experimental approaches provide insights into how changes in bone quality measures influence fracture resistance of bone, the individual contribution of variation in multiscale factors and the interaction of these multiscale modifications cannot be easily deduced with experiments alone. (elsevier.com)
- We are a small multidisciplinary team that uses a combination of cellular, molecular, genetic, biomechanical, live imaging and computational approaches to understand the development of the posterior lateral line primordium. (nih.gov)
- The candidate will use cellular, molecular, genetic, biomechanical, live imaging or computational approaches to understand the development of the posterior lateral line primordium. (nih.gov)
- These characteristics play a major role in identifying and perfecting the optimal approaches to treat diseases of this system when the restoration of biomechanical and me. (researchgate.net)
Mechanical3
- Here we examine the biomechanical responses of the chosen representative membrane complexes under rapid mechanical loadings pertinent to therapeutic shock wave conditions. (unl.edu)
- Moreover, recent findings collectively imply that understanding of the biomechanical environment, such as mechanical stress and oxygen tension on wound bed, is fundamental for further mechanistic investigations of wound healing when NPWT applied. (lboro.ac.uk)
- As the multiscale interaction involving the mechanised packing sociology medical settings as well as microstructural modifications has become analyzed inside canine models, mechanical depiction regarding first embryonic cardio cells can be difficult due to small sample dimensions along with active/passive vascular factors. (reninsignaling.com)
Tissue2
- Demonstrated ability to undertake biomechanical experiments on biological tissue samples is essential (biomechanical testing, data acquisition and analysis). (isbweb.org)
- Hence, our understanding on the biomechanical aspects of the wound tissue during NPWT is rather limited. (lboro.ac.uk)
Behavior1
- The occurrence of these lesions is an bruxism change the magnitude, direction, frequency, increasingly common finding in dental clinical duration and localization of the occlusal contacts, practice with prevalence rates up to 85% in some which result in different biomechanical behavior in populations (QUE et al. (bvsalud.org)
Parameters1
Stiffness1
- Correlating numerical simulations with published in-vitro experiments, we validated the biorheology of the cytoplasm, the elastic response of membrane to external stresses, and the stiffness of the cytoskeleton actin filaments, resulting in an accurate representation of the molecular-level biomechanical microstructures of platelets. (nih.gov)
Molecular1
- 2 biomechanical filling modes, that happen to be wall structure shear tension and blood pressure, tend to be related to distinct molecular paths along with control general morphology through microstructural redesigning. (reninsignaling.com)
Shear1
- Our multiscale computational approach explains the unrecognised role of the vascular anatomy and shear stresses in producing distinct distribution of large forces in vasculature. (nature.com)
Insight1
- WCB gave us a fantastic opportunity to gain a further insight into our Vicon customers and their biomechanical research. (vicon.com)
Interpretation1
- The multiscale entropy: Guidelines for use and interpretation in brain signal analysis. (univ-amu.fr)
Approach2
- A stress based remodeling approach is used to investigate the sensitivity of the collagen architecture in humane eye tissues on the biomechanical response of the lamina cribrosa with a particular focus on the stress environment of the nerve fibers. (uni-weimar.de)
- Bond graph offers such a unified approach to the dynamics of such biomechanical systems. (onacademic.com)
Model1
Strain1
- This methodology was used to find transducer compositions that were appropriate for high strain, low-cycle wearable applications in biomechanical measurement. (digitallibrarynasampe.org)
Medical devices1
- Computational modelling has demonstrated its advantages for investigating biomechanical effectiveness of medical devices where clinically relevant complexities can be introduced in each increment and the range of variables can be alternated simultaneously. (lboro.ac.uk)
Function1
- 2011. Forcing form and function: biomechanical regulation of tumor evolution. . (ucsf.edu)
Complex1
- The geometrical details and biomechanical relationships of the mitral valve-left ventricular apparatus are very complex and have posed as an area of research interest for decades. (researchgate.net)