• Benign salivary gland tumors represent a diverse group of neoplasms with varied clinical behaviors. (medscape.com)
  • [ 1 ] which included multiple newly described benign tumors. (medscape.com)
  • Many carcinomas are solid, while several cystic or mixed lesions are benign. (teknon.es)
  • Fibroblastic connective tissue nevus (FCTN) represents a rare and distinct benign cutaneous mesenchymal lesion of fibroblastic/myofibroblastic lineage, which broadens the spectrum of lesions presently recognized as connective tissue nevus. (lww.com)
  • it is entirely benign and should not be confused with dermatofibrosarcoma protuberans or other neoplasms such as dermatomyofibroma. (lww.com)
  • By understanding these fundamental concepts, the radiologist will be able to accurately differentiate a generally benign paraganglioma from a potentially more aggressive head and neck neoplasm. (springeropen.com)
  • The majority of head and neck paragangliomas are benign and only locally invasive, with only approximately 2-13% of paragangliomas demonstrating malignancy [ 1 ]. (springeropen.com)
  • During a routine outpatient procedure to remove a tiny benign lesion from the eyelid of 10-year-old, anesthesiologist Dr. Sheel Todd failed to reduce and clear the oxygen-rich air in the surgical field. (legalreader.com)
  • The lawsuit states that the young girl had received a squamous papilloma diagnosis, a benign neoplasm on her eyelid. (legalreader.com)
  • See 10 Patients with Neck Masses: Identifying Malignant versus Benign , a Critical Images slideshow, to help identify and manage several types of masses. (naqlafshk.com)
  • The pathogenesis is not fully understood and it is unclear whether it represents a benign vascular neoplasm or a reactive process to a preceding trauma [ 1 ]. (biomedcentral.com)
  • Poroma is a benign adnexal neoplasm of the intraepidermal portion of the sweat gland duct, called the acrosyringium . (clinicaladvisor.com)
  • Ameloblastoma is a benign epithelial odontogenic neoplasm which is common amongst the Yoruba ethinc group. (bvsalud.org)
  • Computed tomography (CT) neck, chest, and abdomen were negative for metastasis. (hindawi.com)
  • The entire lesion was removed with a wide surgical excision. (nih.gov)
  • It recurred on the neck area 4 months after excision and the lesion was removed with surgical resection again. (nih.gov)
  • Fibrolipoma excision, like that described in this report, sometimes may be laborious, because fibrous bands appear to be focally infiltrating adjacent tissues, giving rise to some doubts about the nature of the lesion. (springer.com)
  • Intraoperatively, the excision was more laborious at some points because fibrous bands appeared to be focally infiltrating surrounding tissues, and the neoformation was hard to detach (giving rise to some doubts about the nature of the lesion). (springer.com)
  • Treatment is surgical excision for symptomatic or rapidly enlarging lesions. (aafp.org)
  • Lesions are treated with sur-gical excision and recurrences are rare. (scirp.org)
  • With suspicion of a penile vascular tumor, we performed a local excision of the lesion under general anesthesia. (biomedcentral.com)
  • Nonsquamous cell cancers, including minor salivary gland cancers, sarcomas, and melanomas, account for the other half (see the histologic distribution of hard palate malignant neoplasms and the histologic types and frequencies of minor salivary gland neoplasms of the palate below). (medscape.com)
  • Lipomas represent about 1 to 5 percent of all neoplasms of the oral cavity. (aafp.org)
  • Squamous-cell carcinoma of the oral cavity and pharynx (OSCC) is a malign neoplasm originating in the lining of the epithelium, and is considered to be the most common malign neoplasm of the oral cavity [2]. (bvsalud.org)
  • One challenging feature of head and neck pathology is that a dizzying array of spindle cell lesions occurs here which ranges all the way from reactive, very aggressive forms to malignant lesions. (oldcitypublishing.com)
  • On histopathological analysis, all the classic features were noted and diagnosis of a spindle cell neoplasm was made without any obscurity. (oldcitypublishing.com)
  • Intraosseous myofibromas of the jaw are rare lesions and are part of the wide group of spindle-cell neoplasms and are generally observed in the posterior mandible. (bvsalud.org)
  • citation needed] A low-grade squamous intraepithelial lesion (LSIL or LGSIL) indicates possible cervical dysplasia. (wikipedia.org)
  • citation needed] High-grade squamous intraepithelial lesion (HSIL or HGSIL) indicates moderate or severe cervical intraepithelial neoplasia or carcinoma in situ. (wikipedia.org)
  • As in other head and neck cancer sites, more than 95% of hypopharyngeal malignancies arise from the epithelium of the mucosa and, therefore, are squamous cell cancers. (medscape.com)
  • [ 3 , 4 ] These antibodies are approved for the treatment of advanced EGFR-expressing colorectal cancer, and cetuximab is also approved for treatment of squamous cell carcinoma of the head and neck. (medscape.com)
  • Human Papillomavirus and Risk of Head and Neck Squamous Cell Carcinoma in Iran. (who.int)
  • Oral cancer is a wide-ranging category of location for neoplasms and includes tumors of different etiologies and histopathological profiles, although the vast majority relate to squamous-cell carcinoma (SCC) [1]. (bvsalud.org)
  • Tumors of the major and minor salivary glands account for only 2-4% of head and neck neoplasms. (medscape.com)
  • There are many lesions like rhabdomyosarcoma, fibrosarcoma, liposarcoma, multiple peripheral nerve sheath tumour, angiosarcomas, melanomas, kaposi sarcoma, solitary fibrous tumors, etc., which mimic leiomyosarcoma clinically and histopathologically and therefore immunohistochemical staining with specific markers plays a vital role in arriving at a conclusive diagnosis. (oldcitypublishing.com)
  • Hypopharyngeal cancer is a term used for tumors of a subsite of the upper aerodigestive tract, and like most other subsite designations, the distinction is anatomic rather than pathophysiologic within the group of head and neck malignancies. (medscape.com)
  • Bilateral neck dissections are performed when treating patients with advanced disease, with occult metastases present as much as 62% of the time in patients with T3/T4 tumors. (medscape.com)
  • Imaging is the primary investigative modality for glomus tumors of the head and neck (paragangliomas). (naqlafshk.com)
  • Haller introduced glomus tumors of the head and neck into the medical record in 1762 when he described a mass at the carotid bifurcation that had a glomus body-like structure. (naqlafshk.com)
  • Glomus tumors of the head and neck are associated with 4 primary locations, the jugular bulb, middle ear cavity, vagus nerve, and carotid body. (naqlafshk.com)
  • Although glomus tympanicum tumors are the most common primary neoplasms of the middle ear, these tumors are the rarest of head and neck glomus tumors. (naqlafshk.com)
  • Although glomus tumors usually appear as solitary lesions at 1 site, multiple lesions at multiple sites are not uncommon (see the image below). (naqlafshk.com)
  • Multiple glomus tumors. (naqlafshk.com)
  • Gardner syndrome is an autosomal dominant form of polyposis characterized by the presence of multiple polyps in the colon together with tumors outside the colon. (wikipedia.org)
  • Anteriorly, the lesion extended subcutaneously, showing postcontrast enhancement within the cutaneous and subcutaneous soft tissues. (hindawi.com)
  • Although these drugs have been proven to be very effective for normally untreatable advanced neoplasms, EGFRIs cause cutaneous side effects in 50% or more of patients undergoing treatment. (medscape.com)
  • Compared to conventional lipoma, fibrolipoma of the tongue is a very rare lesion that accounts for around 25-40% of tongue lipomas, and until now, to the best of our knowledge, only 14 cases have been described in which histological diagnosis of fibrolipoma was specifically confirmed. (springer.com)
  • Because of its histological characteristics, abundance of connective and secondary changes/atrophy, fibrolipoma may appear as infiltrating adjacent tissues and may cause doubts of differential diagnosis with malignant infiltrating lesions. (springer.com)
  • Particularly rare is the fibrolipoma that, sometimes, but for its histological characteristics, may cause doubts of differential diagnosis with infiltrating lesions. (springer.com)
  • Panendoscopy (ie, laryngoscopy, bronchoscopy, esophagoscopy, nasopharyngoscopy) has traditionally been the criterion standard for the diagnosis of second primary lesions. (medscape.com)
  • With each chapter written by experts in the many fields that comprise head and neck oncology and surgery, this compendium provides a unique, multidisciplinary perspective on the diagnosis and management of these patients. (novapublishers.com)
  • Desmoid fibromatosis should be included as differentials while evaluating lesions of the neck even in elderly males and a radiological diagnosis of neurocysticercosis in such lesions always warrants further evaluation with histopathology. (jocr.co.in)
  • Often, the diagnosis of multiple myeloma is made incidentally during routine blood tests for other conditions. (the-medical-dictionary.com)
  • Cervical lymph node biopsy confirmed a diagnosis of multiple myeloma. (the-medical-dictionary.com)
  • HPV and head and neck cancers: Towards early diagnosis and prevention. (who.int)
  • MRI pelvis was suggestive of 72 × 58 × 73 mm sized lobulated altered signal intensity lesion arising from the posterior wall of rectum. (omicsonline.org)
  • These soft tissue lesions had an exophytic component along the anterior and posterior aspect of the right tibia. (hindawi.com)
  • The lesion arising from the posterior aspect had an axial dimension of 5.1 cm × 4.1 cm with a craniocaudal dimension of 5.7 cm. (hindawi.com)
  • The posterior lesion showed gastrocnemius infiltration. (hindawi.com)
  • We initiated treatment with oral amoxicillin/clavulanic acid and requested a computed tomography scan of the head and neck to assess the vascularity and amenability for biopsy of the mass. (cdc.gov)
  • A sample of the friable mass from the biopsy sent for histologic examination revealed multiple, variously sized, spherical subepidermal structures, the largest with thickened walls. (cdc.gov)
  • Perform excisional biopsy on suggestive lesions. (medscape.com)
  • blood transfusion), spinal cord, lung cancer (oncology), respiratory cancer, radiology Background Multiple myeloma is a malignant proliferation of plasma cells mostly affecting the bone marrow and commonly presents with anaemia, hypercalcaemia, renal dysfunction, bone and skeletal involvement. (2011globalhealth.org)
  • The most common sites of extramedullary solitary plasmacytoma include upper airway tract, digestive tract, lymphatic systems and head and neck regions.4 5 An extramedullary plasmacytoma can arise in a myeloma patient during the disease irrespective of duration of illness, and it typically represents advanced disease. (2011globalhealth.org)
  • Multiple myeloma (also known as MM , myeloma , plasma cell myeloma , or as Kahler's disease after Otto Kahler) is a presently incurable hematological malignancy of plasma cells, the cells of the immune system that produce antibodies. (the-medical-dictionary.com)
  • The workup of suspected multiple myeloma includes a skeletal survey. (the-medical-dictionary.com)
  • Multiple myeloma, which primarily affects the elderly, is rare in the head and neck. (the-medical-dictionary.com)
  • Multiple myeloma, a rare malignancy of plasma cells, was first described in 1950 as an abnormal production of immunoglobulins. (the-medical-dictionary.com)
  • Multiple myeloma represents fewer than 2% of all head and neck cancers. (the-medical-dictionary.com)
  • The etiology of multiple myeloma is unclear. (the-medical-dictionary.com)
  • 1 Although it is the third-most-common primary malignant bone tumor (following osteosarcoma and multiple myeloma) 2 and the second-most-common sarcoma arising in bone, 1 most cases occur in the pelvic bones, proximal femur, proximal humerus, distal femur, and the ribs. (ajnr.org)
  • Множинна мієлома Multiple myeloma is a cancer of plasma cells that produce monoclonal immunoglobulin and invade and destroy adjacent bone tissue. (msdmanuals.com)
  • Common manifestations include lytic lesions in bones causing. (msdmanuals.com)
  • Successful management of these neoplasms relies on accurate clinical and diagnostic assessment, as well as appropriate therapeutic intervention. (medscape.com)
  • Two different clinical presentations producing distinct clinical symptoms and pathologic lesions have been identified in affected falcons, denoted as neurotropic velogenic and viscerotropic velogenic forms. (bioone.org)
  • Musculoskeletal fibromatoses represent a wide spectrum of fibroblastic and myofibroblastic neoplasms with similar pathologic appearances and variable clinical behavior. (jocr.co.in)
  • Myofibroma is a rare lesion, that is relatively more common in tissues of the head and neck and which can originate from soft tissue and bone 1 . (bvsalud.org)
  • It was first described by Stout in 1954 3 as congenital generalized myofibromatosis and in 1989, Smith 4 introduced the most widely accepted term, myofibroma, for solitary lesions. (bvsalud.org)
  • The frequency of distant metastases is also among the highest of all head and neck cancers. (medscape.com)
  • Mouth (oral) cancer is a major neoplasm worldwide and accounts for most head and neck cancers. (medscape.com)
  • Any single lesion persisting for more than 3 weeks should be regarded with suspicion. (medscape.com)
  • Other types of pathology in the brain stem segment are neoplasms (mostly glioma and metastases), vascular lesions (infarction, cavernoma) and infections (rhombencephalitis). (radiologyassistant.nl)
  • We report a case of malignant proliferating trichilemmal tumor showing multiple distant metastases. (nih.gov)
  • There was evidence of multiple metastases on CNS and mediastinal lymph nodes after 6 months. (nih.gov)
  • A syndrome of multiple collagenous nevi is seen in some families of German Shepherds and is called nodular dermatofibrosis . (msdvetmanual.com)
  • He had 131-I iodine avid nodular lesion in the left parotid gland which was later proven to be oncocytoma on histopathology. (bvsalud.org)
  • Most patients presented with a solitary, slowly growing, painless plaque-like or nodular skin lesion. (lww.com)
  • Solid primary lesions of the hyoid bone are exceedingly rare and the reported cases have included plasmacytoma, osteosarcoma, giant cell tumor, aneurysmal bone cysts, osteoma, chondroma, and chondrosarcoma. (ajnr.org)
  • EOS is an extremely rare tumour of the head and neck region which often requires extensive surgical resection with or without adjuvant radiotherapy. (bvsalud.org)
  • The imaging evaluation of head and neck paragangliomas utilizes multiple cross-sectional imaging modalities to evaluate for extent of disease and to help guide surgical management by evaluating for osseous and neurovascular involvement. (springeropen.com)
  • In 1852, Horace Green reported the first surgical resection of a laryngeal lesion, a polyp in the ventricle, removed under direct vision. (medscape.com)
  • Pathology in the brain stem segment is most often due to demyelination by multiple sclerosis. (radiologyassistant.nl)
  • Less common causes include vascular and inflammatory lesions and haematological malignancies. (2011globalhealth.org)
  • Premalignant mucosal lesions evolve into hyperproliferative lesions that develop the capacity to enlarge, to invade local structures, to invade lymphatics to spread to regional lymph nodes, and to invade vascular channels to metastasize to other organs. (medscape.com)
  • Epithelioid hemangioma, first described in 1969, is a rare vascular lesion that typically arises on the head and distal extremities. (biomedcentral.com)
  • There are also combination therapies that affect multiple receptors such as lapatinib (approved for human epidermal growth factor receptor 2-positive [HER2+] breast cancer) and afatinib (approved for non-small cell lung cancer), which inhibit both the EGFR and HER2 receptors, and vandetanib (approved for advanced medullary thyroid cancer), which inhibits EGFR, vascular endothelial growth factor (VEGFR), and rearranged during transfection (RET) activities. (medscape.com)
  • This is the most common type of glomus tumor of the head and neck. (naqlafshk.com)
  • Since this lesion is rarely seen in the mandible, it can be misdiagnosed as an odontogenic cyst or tumor, and there are previous reports of misdiagnosis preventing appropriate management 7,8 . (bvsalud.org)
  • Moore, C., Barron, J ., Manuscript: JNC-2022-0022.R1 Title: Investigating the NLRP3 Inflammasome and its Regulator miR-223-3p in Multiple Sclerosis and Experimental Demyelination. (mun.ca)
  • 1) It accounts for approximately 10 to 15% of all hematologic malignancies, 1% of all malignant neoplasms in whites and 2% in blacks, and 2% of deaths from all malignancies. (the-medical-dictionary.com)
  • Cancer of the soft palate accounts for approximately 2% of head and neck mucosal malignancies. (medscape.com)
  • PET scan demonstrated FDG avid lesions in the right parotid gland, cervical lymph nodes and other distant sites. (bvsalud.org)
  • Extraosseous osteosarcoma is a rare malignant soft tissue neoplasm, and extraosseous osteosarcoma of the parotid gland is very rare. (bvsalud.org)
  • An MRI scan was done which showed a 12 × 10 × 8 cm lesion centred in the right parotid gland, involving paraspinal muscles, C1-C2 vertebrae and extending into the parapharyngeal space. (bvsalud.org)
  • Papillary thyroid carcinoma (PTC) is the most common differentiated thyroid neoplasm. (bvsalud.org)
  • FCTN occurs most commonly as a plaque on the trunk and head/neck of children, involves deep dermis and superficial subcutis, and stains mainly for CD34. (lww.com)
  • When stress or DNA damage occurs in the body and the phosphorylation of p53 occurs on multiple sites, Mdm2 does not associate with p53. (shu.edu)
  • 5,6 Poromatosis, or the emergence of multiple poromas in an acral or a widespread distribution, is also rare and occurs more commonly in patients with a history of immunosuppression from either chemotherapy or radiation. (clinicaladvisor.com)
  • SCC extension beyond the hard palate occurs in up to 70% of lesions. (medscape.com)
  • Early and moderately advanced lesions are usually managed with supraglottic laryngectomy or radiotherapy. (medscape.com)
  • Advanced lesions are usually treated with total laryngectomy, preoperative or postoperative radiotherapy, and, possibly, chemotherapy, since combined-modality therapy produces better results than a single modality alone. (medscape.com)
  • It can be divided into six categories: Thyroid cytopathology of Bethesda category III with clotting artifact Category IV Category V with intranuclear cytoplasmic inclusion Category V with nuclear groove (arrow) Cytopathology suspicious for Hürthle cell neoplasm (Bethesda category IV, rather than Hürthle cell hyperplasia), Pap stain. (wikipedia.org)
  • A contrast-enhanced CT scan showed an oval-shaped neoplasm, with distinct margins, and a rather patchy density (Fig. 2 ). (springer.com)
  • Computed tomography (CT) scanning and magnetic resonance imaging (MRI) are useful studies in evaluating the spread of supraglottic lesions (see CT Scan of the Larynx ). (medscape.com)
  • A penile ultrasound scan demonstrated a well circumscribed lesion (6 × 8 mm) over the dorsal aspect of the penis within the subcutaneous tissue, superficial to the corpus cavernosum (Figure 1 ). (biomedcentral.com)
  • The patient was planned for a magnetic resonance imaging scan which showed ill-defined lobulated mass in the right trapezius of size 4 × 7 × 5.4 cm, which was heterogeneous in T2, isointense in T1, multiple ovoid calcifications, and was suspected with cysticercosis or fibroma. (jocr.co.in)
  • A strong understanding of the biologic behavior of the various types of lesions allows the development of an appropriate treatment plan tailored to each individual patient affected. (medscape.com)
  • 30 years old) and involving the head and neck have more aggressive behavior than those found in other sites and age groups. (jocr.co.in)
  • The patient demonstrated a round mass in the right occipital area for 12 months and the lesion grew rapidly to assume 8 x 6.5 x 4 cm in diameter, with areas of superficial erosion and crusting within the recent 3 months. (nih.gov)
  • 51 year old female patient who was a known case of PTC with a history of multiple surgeries, radioactive iodine therapy (RAI) and oral chemotherapy presented with a painful right parotid mass. (bvsalud.org)
  • He was evaluated clinically, and a large mass was noted over the upper aspect of the right upper neck, extending to the occipital and parotid regions. (bvsalud.org)
  • Ultrasound is typically utilized early in the diagnostic process, often for initial evaluation of a palpable neck mass. (springeropen.com)
  • Physical examination revealed a nontender, bluish, fluctuant sublingual mass with no obvious extension into the neck (see accompanying figure ) . (aafp.org)
  • Cervical or plunging ranulas, which penetrate through the belly of the mylohyoid muscle, often produce an externally visible neck mass. (aafp.org)
  • Congenital neoplasms are common in large animals. (msdvetmanual.com)
  • Head and neck paragangliomas most common anatomic locations include the carotid space, jugular foramen, middle ear, and along the course of the vagus nerve. (springeropen.com)
  • Paragangliomas of the head and neck are more common in females, with this predilection most common in jugular (3:1) and tympanic subtypes (6:1) [ 6 ]. (springeropen.com)
  • As a common condition with a high success rate with removal surgery, the girl's doctor recommended the procedure to remove the lesion. (legalreader.com)
  • Laryngeal cancer is the second most common type of head and neck cancer worldwide. (medscape.com)
  • Any area of the body can be affected by PG, the most common site being the pretibial area, where the lesions may show bilateral involvement. (jcadonline.com)
  • Slow insidious growth is common, and lesions are usually painless. (jocr.co.in)
  • In extensive lesions extending into the nasopharynx, middle ear effusion is common. (medscape.com)
  • The lesions were excised and no recurrence was no- ticed after six months. (scirp.org)
  • Such lesions have increased local recurrence rates [3]. (jocr.co.in)
  • Histopathological analysis revealed sheets and aggregates of neoplasm replacing bone marrow interspersed with sclerotic bony fragments. (hindawi.com)
  • Histopathology of the right tibial lesion was reviewed at IHHN, revealing sheets and aggregates of neoplastic cells replacing bone marrow interspersed with sclerotic bony fragments. (hindawi.com)
  • To obtain credit, read Round, confluent patches on infant's face and Small, erythematous papules on the face, scalp, and neck . (clinicaladvisor.com)
  • One dog with a giant congenital pigmented nevus had a malignant melanoma develop within the lesion. (msdvetmanual.com)
  • Gardner syndrome can be identified based on oral findings, including multiple impacted and supernumerary teeth , multiple jaw osteomas that give a "cotton-wool" appearance to the jaws, as well as multiple odontomas , congenital hypertrophy of the retinal pigment epithelium (CHRPE), in addition to multiple adenomatous polyps of the colon. (wikipedia.org)
  • In some cases these lesions can lead to invasive cervical cancer, if not followed appropriately. (wikipedia.org)
  • The patient had multiple, firm, mobile, nontender lymph nodes palpable in the submandibular and cervical regions, measuring 0.5 to 1 cm in diameter. (contemporarypediatrics.com)
  • The girl was ultimately admitted to WellStar Cobb Hospital with seven significant second-degree burns on multiple sites of her head, face and neck, covering surface areas as large as 8×5 centimeters. (legalreader.com)
  • Less frequently (range, 1%-12%) 1 chondrosarcoma originates in the head and neck region, with the skull base, maxilla, and larynx more commonly involved. (ajnr.org)
  • Additionally, we will discuss other differential considerations for lesions found in these locations. (springeropen.com)
  • Histopathological examination revealed a well circumscribed, unencapsulated lesion (Figure 2 ) composed of central sheets of plump epithelioid cells with scattered vessels at the periphery. (biomedcentral.com)
  • However, the salient feature of penile cancer is painless ulcerative or cauliflower lesions. (biomedcentral.com)
  • Medical imaging contains multiple imaging sequences or modalities, such as magnetic resonance imaging (MRI), computed tomography (CT), and positron emission tomography (PET), providing complementary information ( 5 - 8 ). (frontiersin.org)
  • We report the case of a 20 year old male patient who presented with history of right neck swelling since 6 years for which he had undergone right parotid surgery 5 years ago. (bvsalud.org)
  • The WellStar doctor performed a successful graft surgery to her head, but because of the fire, she still suffers from large, visible facial burns and skin graft scarring. (legalreader.com)
  • This textbook presents a succinct yet comprehensive overview of the current essential topics in the multidisciplinary care of head and neck cancer patients. (novapublishers.com)
  • Finally, this textbook's outline format, clear and concise language, and rich set of practice guidelines make it a trusted resource for nonmedical professionals hoping to learn more about head and neck cancer patients and their treatments. (novapublishers.com)
  • Prevalence of human papillomavirus types in head and neck cancer sub-sites in the Indian population. (who.int)
  • These lesions are categorized by location (superficial or deep). (jocr.co.in)