• The exact underlying cause of polymyalgia rheumatica is not known, however, patients with temporal arteritis, a disease characterized by inflammatory changes in the blood vessels also suffer from polymyalgia rheumatic. (iewebsites.com)
  • Acquired immunodeficiency syndrome (AIDS) is a condition of by profound impairment of the immune system. (iewebsites.com)
  • A. What disorders do we evaluate under the immune system disorders listings? (ssa.gov)
  • 1. We evaluate immune system disorders that cause dysfunction in one or more components of your immune system. (ssa.gov)
  • Immune system disorders may result in recurrent and unusual infections, or inflammation and dysfunction of the body's own tissues. (ssa.gov)
  • Immune system disorders can cause a deficit in a single organ or body system that results in extreme (that is, very serious) loss of function. (ssa.gov)
  • B. What information do we need to show that you have an immune system disorder? (ssa.gov)
  • Generally, we need your medical history, a report(s) of a physical examination, a report(s) of laboratory findings, and in some instances, appropriate medically acceptable imaging or tissue biopsy reports to show that you have an immune system disorder. (ssa.gov)
  • The precise meaning will depend on the specific immune system disorder, the usual course of the disorder, and the other circumstances of your clinical course. (ssa.gov)
  • If a person does not respond well to steroid therapy, a doctor may prescribe cytotoxic drugs that stop the immune system cells that cause inflammation. (medicalnewstoday.com)
  • Autoimmune disease is the pathologic result of autoimmunity, whereby the immune system attacks the person's healthy body tissues. (basicmedicalkey.com)
  • Many of these are driven by the same immunologic mechanisms responsible for the drugs' therapeutic effects, namely blockade of inhibitory mechanisms that suppress the immune system and protect body tissues from an unconstrained acute or chronic immune response. (bmj.com)
  • Antibody: a protein produced by the immune system to identify and neutralize foreign substances such as bacteria and viruses. (drpaulkilgore.com)
  • A significant loss of the electrical charge of the cell membrane may be catastrophic - especially for the circulatory system, immune system and neuromuscular system. (dna-biopharm-sa.com)
  • It can damage all the organ systems, but especially affects the brain, heart, liver, pancreas and immune system . (wikipedia.org)
  • Under normal conditions, the immune system reacts to the presence of a viral or bacterial illness by producing a variety of immune cells designed to attack the invading viruses or bacteria. (encyclopedia.com)
  • Nervous system (e.g., myasthenia gravis [a disorder of the neuromuscular junction], multiple sclerosis, Guillain-Barré Syndrome, autoimmune autonomic failure). (basicmedicalkey.com)
  • Out of these, multiple sclerosis (MS) is the most common cause of demyelinating ON. (openophthalmologyjournal.com)
  • Controlled High-Risk Subjects Avonex ® Multiple Sclerosis Prevention Study "CHAMPS", Betaferon in Newly Emerging Multiple Sclerosis for Initial Treatment "BENEFIT" and Early Treatment of MS study "ETOMS" have reported that treatment with interferon β-1a,b results in reduced risk of MS and MRI characteristics of ON. (openophthalmologyjournal.com)
  • It has also been shown to be effective in supporting a host of conditions, including multiple sclerosis, diabetes, asthma and immune disorders. (dna-biopharm-sa.com)
  • The first trial applications of Ca-AEP were for the treatment of multiple sclerosis (MS). In 1967 the German Health Authority approved the use of Ca-AEP for MS. MS, an inflammatory demyelinating condition, is one of the most common diseases of the central nervous system (brain and spinal cord). (dna-biopharm-sa.com)
  • In multiple sclerosis these scars appear at different times and in different areas of the brain and spinal cord - thus, the term Multiple Sclerosis literally means "many scars. (dna-biopharm-sa.com)
  • The central nervous system (CNS) is extremely resistant to infection by bacterial pathogens due to a combination of protective effects of its bony structures (skull and vertebral column), the meninges, and the blood-brain barrier. (medscape.com)
  • Meningitis is the inflammation of the leptomeninges and the most common central nervous system (CNS) bacterial infection. (medscape.com)
  • The incidence of central nervous system (CNS) TB is related to the prevalence of TB in the community, and it is still the most common type of chronic CNS infection in developing countries. (medscape.com)
  • These bacteria may infect the central nervous system (CNS) during primary or reactivated infection. (msdmanuals.com)
  • Syphilitic infection of the nervous system results in the most chronic, insidious meningeal inflammatory process known. (medscape.com)
  • Though commonly associated with AIDS/HIV infection, it has been reported to be pathogenic in immunocompetent patients. (bvsalud.org)
  • to be applied?APRICOT : AIDS Pegasys Ribavirin International CO-infection Trial?APSAC: Anisolyated plasminogen streptokinase activator complex?APT: Alum-precipitated toxoid?aPTT: Activated partial thromboplastin time?APTT: Activated partial thromboplastin time?aq. (kuwaitpharmacy.com)
  • These disorders can be classified as systemic, affecting multiple organs or tissues (e.g., connective tissue autoimmune diseases such as systemic lupus erythematosus [ SLE ], Sjögren syndrome [ SjS ], or scleroderma), or organ specific, targeting one particular organ. (basicmedicalkey.com)
  • IgG4-related disease is a multiorgan immune-mediated condition composed of multiple disorders that share particular pathologic, serologic, and clinical features. (basicmedicalkey.com)
  • A significant proportion of dementing illnesses in the elderly are attributed to multiple pathologic processes that may confer their additive or synergistic effects to the development of cognitive decline. (mahidol.ac.th)
  • He closely collaborates with investigators from Case Cardiovascular Research Institute, Institute for Transformative Molecular Medicine and Harrington Heart & Vascular Institute to bring together researchers of multiple disciplines to link physiologic and pathologic function at the in vivo. (symbiosisonlinepublishing.com)
  • Giant cell arteritis in association with cerebral amyloid angiopathy: immunohistochemical and molecular studies. (mahidol.ac.th)
  • Selection of laboratory and/or imaging studies to rule out conditions other than migraine headache is determined by the individual presentation (eg, erythrocyte sedimentation rate and C-reactive protein levels may be appropriate to exclude temporal/giant cell arteritis). (medscape.com)
  • They can also cause lesser degrees of limitations in two or more organs or body systems, and when associated with symptoms or signs, such as severe fatigue, fever, malaise, diffuse musculoskeletal pain, or involuntary weight loss, can also result in extreme limitation. (ssa.gov)
  • The symptoms of transverse myelitis are due to damage and/or destruction of the myelin sheath , the fatty white covering of nerve fibers that serves both to insulate the nerve fibers and to speed nervous conduction along them. (encyclopedia.com)
  • Areas of missing myelin and areas of scarring along the affected nerves result in slowed or disrupted nervous conduction and muscle dysfunction. (encyclopedia.com)
  • Aberrant JAK expression is associated with multiple autoimmune or inflammatory conditions. (justia.com)
  • An angiogram revealed multiple and bilateral short segments of narrowing and beading involving proximal and distal median cerebral vessels, with no evidence of arteriovenous malformation nor aneurysm (Fig. 1 , right side). (openaidsjournal.com)
  • Distal sensory neuropathy occurs in up to 30% of patients with AIDS, usually late in the disease. (unboundmedicine.com)
  • We are proud to provide access to our quality medicines to healthcare systems and patients in both developing and emerging markets. (pfizer.com)
  • JAK enzymes have been shown to be important in the differentiation and function of multiple cell types important in inflammatory disease and autoimmune disease including natural killer cells, B cells, and T helper cell types. (justia.com)
  • Robust and reliable disease models related to Cardiovascular, Urinary, and Central Nervous System have been established. (symbiosisonlinepublishing.com)
  • AIDS-like syndrome: AIDS-like disease (illness) (syndrome) ARC AIDS-related complex Pre-AIDS AIDS-related conditions Prodromal-AIDS 3. (cdc.gov)
  • The internal composition of axons is a complex linear microtubular system designed to maintain the integrity of the membranes and the transport of substances (e.g., neurotransmitters) between dendrites and through cell body to the axon 6 , 7 ( Fig. 35-3 ). (nursekey.com)
  • Ca-AEP facilitates the cellular exchange of inorganic electrolytes in cells and aids the absorption of nutrient substances such as fatty acids, amino acids, carbohydrates, vitamins, hormones and steroids through the 'active transport pores' of cell membranes. (dna-biopharm-sa.com)
  • From a superior view, the cerebrum is essentially divided into quarters by the median longitudinal cerebral fissure and the coronal central sulcus. (gov.gy)
  • ABBR: AN Hearing loss that results from nerve damage or impaired nervous system processing of normal signals received from sensory hair cells in the Organ of Corti. (unboundmedicine.com)
  • Our group pioneered the reproducible quantification of HIV-1 RNA in brain tissue homogenates to determine the regional distribution of brain viral loads in AIDS autopsies. (mahidol.ac.th)
  • The network supports a broad variety of clinical, epidemiologic, translational research, biospecimen repository and clinical trials, with multiple funding sources from NIH, Arthritis Foundation, not-for-for profit foundations and biopharma. (stanford.edu)
  • Soontornniyomkij V, Nieto-Rodríguez JA, Martínez AJ, Kingsley LA, Achim CL, Wiley CA. Brain HIV burden and length of survival after AIDS diagnosis. (mahidol.ac.th)
  • What is PMR?Polymyalgia rheumatica (PMR) is a medical condition characterized by pain, swelling and restricted movement in multiple joints especially the neck, shoulder and hip joints. (iewebsites.com)
  • Ear drops?AutoPap: Computer-assisted cytology interpretation system?AV: Aortic valve?AV: Atrioventricular?A-V: Arteriovenous?AVERT: Atorvastatin Versus Revascularization treatment?AVID: ?AVM: Arteriovenous Malformation?AVNRT: AV nodal reentry tachycardia?AVP: Arginine vasopressin?AVR: Aortic valve replacement?AVR: Augmented V lead, right arm (ECG)?AVRT: ?AVS: Arteriovenous shunt?AWS: Alcohol withdrawal syndrome?AXR: Abdominal X ray?AZF: Azoospermia factor genes?AZT: Azidothymidine (zidovudine)?B & O: Belladonna and opium?B Bx. (kuwaitpharmacy.com)
  • In particular, the JAK family of cellular protein tyrosine kinases (JAK1, JAK2, JAK3, and TYK2) play a central role in cytokine signaling (Kisseleva et al. (justia.com)
  • Hitler called Mein Kampf deficiency inherited for what he was to produce ' multiple Thanks ' affecting his active Putsch in Munich in November 1923. (shotglass.org)
  • 1. AIDS: Acquired immune deficiency syndrome Acquired immunodeficiency syndrome 2. (cdc.gov)
  • This review deals with some of the structural, functional and metabolic features of aging nervous system and discusses briefly the functional consequences. (ijpmonline.org)
  • In addition, the HIV-1 RNA load generally correlated well with HIV gp41 protein load assessed by our immunohistochemical semi-quantitative scoring system. (mahidol.ac.th)
  • Because these venous channels are valveless, compression of the thorax, abdomen, or pelvis, as occurs during heavy coughing and straining, may force venous blood from these regions into the internal vertebral venous system and from it into the dural venous sinuses. (gov.gy)
  • We applied two highly sensitive RNA assays based on either signal amplification (branched-DNA assay, Quantiplex HIV RNA, Chiron Corporation) or template amplification (RT-PCR assay, Amplicor HIV-1 Monitor, Roche Molecular Systems). (mahidol.ac.th)
  • The nervous system is very sensitive to radiotherapy. (asso.fr)