CD44 is a receptor for hyaluronic acid and internalizes metals bound to hyaluronic acid and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). (wikipedia.org)
CD447
Osteopontin mediates biological function through signal transduction by binding to the cell surface receptors such as integrin αvβ3 and CD44 [ 5 ]. (biomedcentral.com)
Our recent studies have shown an increase in the surface expression of CD44 isoforms (sCD44 and v4-v10 variant CD44) in prostate cancer cells over-expressing osteopontin (PC3/OPN) [ 15 ]. (biomedcentral.com)
The CD44 antigen is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. (wikipedia.org)
CD44 has been referred to as HCAM (homing cell adhesion molecule), Pgp-1 (phagocytic glycoprotein-1), Hermes antigen, lymphocyte homing receptor, ECM-III, and HUTCH-1. (wikipedia.org)
CD44 is a multistructural and multifunctional cell surface molecule involved in cell proliferation, cell differentiation, cell migration, angiogenesis, presentation of cytokines, chemokines, and growth factors to the corresponding receptors, and docking of proteases at the cell membrane, as well as in signaling for cell survival. (wikipedia.org)
HA can bind to the three main classes of cell surface receptors, each having a unique role: CD44 (a membrane glycoprotein), RHAMM (the receptor for hyaluronate-mediated motility), and ICAM-1 (intercellular adhesion molecule 1).CD44 is the most widely distributed cell surface receptor recognised for HA binding Other ligands that interact with CD44 include osteopontin, collagens, and matrix metalloproteinases (MMPs). (biotechnolabs.com)
According to the most recent research, CD44 is a multifunctional, cell-surface conjugated protein found on many different types of cells. (biotechnolabs.com)
Receptor1
CD14 also serves as a multifunctional lipopolysaccharide receptor, and is released to the serum both as a secreted and enzymatically cleaved GPI-anchored form. (thermofisher.com)
Abstract1
Hier de conclusie van deze review en daaronder een studie abstract met ranpirnasse uit 2002 met bijzonder goede resultaten op de mediane overlevingstijd. (kanker-actueel.nl)
Found2
Lactoferrin (Lf), a glycoprotein found in body fluids, plays a key role in many of the biological mechanisms that occur in the human body. (umk.pl)
Tumor markers are soluble glycoproteins that are found in the blood, urine, or tissues of patients with certain types of cancer. (medscape.com)
Human3
Description: The 61D3 monoclonal antibody reacts with human CD14, a 53-55 kDa GPI-linked glycoprotein. (thermofisher.com)
Description: Quantitativecompetitive ELISA kit for measuring Human leucine-rich alpha-2 glycoprotein 1 (LRG1) in samples from serum, urine, cell culture supernates, tissue homogenates. (resourcerecovery.be)
Description: Quantitative sandwich ELISA for measuring Human Leucine-rich alpha-2 glycoprotein 1 (LRG1) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids. (resourcerecovery.be)
Protein1
The family of glycophosphoproteins comprising osteopontin, bone sialoprotein, dentin matrix protein 1, dentin sialophosphoprotein and matrix extracellular phosphoglycoprotein - small integrin-binding ligand N-linked glycoproteins (SIBLINGs) - are emerging as important players in many stages of cancer progression. (nih.gov)
Matrix1
CD44 is a receptor for hyaluronic acid and internalizes metals bound to hyaluronic acid and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). (wikipedia.org)
Blood1
Tumor markers are soluble glycoproteins that are found in the blood, urine, or tissues of patients with certain types of cancer. (medscape.com)