• However, the microbial metabolic pathway of the fungicide and the genetic systems driving its degradation by strain P3 remain unknown. (nature.com)
  • Therefore, elucidation of the microbial metabolic pathway of OPP is a prerequisite for the downstream exploitation of strain P3 in any environmental application. (nature.com)
  • 6 identified a gene cluster, hbpCAD , encoding the upper metabolic pathway of OPP which involves the transformation of OPP to 2-hydroxypenta-2,4-dienoateand benzoic acid (BA). (nature.com)
  • The downstream transformation of BA involved a meta -cleavage pathway, although its genetic organization and function was not revealed and the overall network of genes driving the full metabolic pathway of OPP is still not known. (nature.com)
  • Enriched metabolic pathways for both total fat (%) and fat. (lu.se)
  • Enriched metabolic pathways for both total fat (%) and fat distribution included protein synthesis, branched-chain amino acids biosynthesis and metabolism, glycerophospholipid metabolism and sphingolipid metabolism. (lu.se)
  • The structure-metabolism relationship was also discussed, which generally agreed well with previously reported metabolic pathways of other synthetic cannabinoids. (bvsalud.org)
  • Efficient FAD/FADH2 regeneration is vital for enzymatic biocatalysis and metabolic pathway optimization. (bvsalud.org)
  • 2. Develop and implement the pathway. (medtronic.com)
  • We then implement the pathway in a photosynthetic organism Synechococcus elongates PCC7942, and show that it increases the intracellular acetyl-CoA pool and enhances bicarbonate assimilation by roughly 2-fold. (osti.gov)
  • We show that the cluster has formed de novo since the divergence of oats in a subtelomeric region of the genome that lacks homology with other grasses, and that gene order is approximately colinear with the biosynthetic pathway. (cas.cz)
  • In addition, the decrease in the abscisic acid (ABA)/gibberellic acid (GA) ratio regulated by biosynthetic signal transduction pathway enhanced cold resistance in Tg C. japonica, suggesting that hormones may regulate the difference in cold responsiveness. (figshare.com)
  • We speculate that the positioning of the late pathway genes furthest away from the telomere may mitigate against a 'self-poisoning' scenario in which toxic intermediates accumulate as a result of telomeric gene deletions. (cas.cz)
  • This ancillary, longitudinal, observational, candidate gene association study investigated the hypothesis that epigenetic and genetic variability of genes in the iron homeostasis pathway may account for a proportion of variability in patient outcomes post-aSAH. (pitt.edu)
  • To explore the common genes and pathogenic pathways among different fibrotic diseases, we collected all the reported genes of the eight fibrotic diseases: eye fibrosis, heart fibrosis, hepatic fibrosis, intestinal fibrosis, lung fibrosis, pancreas fibrosis, renal fibrosis, and skin fibrosis. (frontiersin.org)
  • Moreover, we interestingly found overlaps of pathways between renal fibrosis and skin fibrosis, such as GO:1901890-positive regulation of cell junction assembly, as well as common regulatory genes, such as CTGF, which is the key molecule regulating fibrogenesis. (frontiersin.org)
  • Over-representation analysis (ORA) is frequently used to assess the statistical enrichment of known gene sets (e.g. pathways) in a discrete or ranked list of genes. (pathwaycommons.org)
  • Each gene set is described by a name, a description, and the genes in the gene set: participants in a pathway are specified with one or several HGNC symbols (we can also provide another file using UniProt accession numbers instead). (pathwaycommons.org)
  • Includes 7.5" all-in-one light stakes to outline walkways and pathways. (christmaslightsetc.com)
  • Explore from our collection of sandstone stepping stones for walkways or pathways and give your property's exteriors the splendidness it deserves. (stratastones.co.uk)
  • The MAP-kinase pathway is a major pathway in relaying signals from the plasma membrane into the nucleus. (europa.eu)
  • AT13148 is a novel oral multi-AGC kinase inhibitor with potent pharmacodynamic and antitumor activity, which shows a distinct mechanism of action from other AKT inhibitors. (adooq.com)
  • In this study, we used a mathematical model commonly employed by the U.S. Environmental Protection Agency to estimate average daily intake of fluoride via all applicable exposure pathways contributing to fluorosis risk for infants and children living in hypothetical fluoridated and non-fluoridated communities. (cdc.gov)
  • We also estimated hazard quotients for each exposure pathway and hazard indices for exposure conditions representative of central tendency exposure (CTE) and reasonable maximum exposure (RME) conditions. (cdc.gov)
  • The exposure pathways considered were uptake of fluoride via fluoridated drinking water, beverages, cow's milk, foods, and fluoride supplements for both age groups. (cdc.gov)
  • Individuals who live in multi-unit housing, including apartments, are particularly susceptible to involuntary secondhand smoke exposure in the home. (cdc.gov)
  • Exposure to secondhand smoke in multi-unit housing facilities may vary depending on building structure, building age, and where smoking is allowed. (cdc.gov)
  • 8 Smokefree policies to prohibit smoking in living units and common areas of multi-unit housing facilities are legally permissible and the most effective way to fully protect residents from involuntary exposure to secondhand smoke. (cdc.gov)
  • The method described in this document is for assessing multi-element exposure by analyzing urine using of inductively coupled-plasma mass spectrometry (ICP-MS). This method achieves rapid and accurate quantification of urinary arsenic. (cdc.gov)
  • All pathways and interactions within the database are available in BioPAX Level 3. (pathwaycommons.org)
  • To make it easier to use all of the pathway information in Pathway Commons with typical network analysis tools, we developed a set of rules to reduce BioPAX interactions to pairwise (or binary) relationships. (pathwaycommons.org)
  • This format does not contain any cross-species interactions and is available for all pathways and interactions within this database. (pathwaycommons.org)
  • A note about identifiers: We uniquely mapped selected protein and gene identifiers, such as HGNC symbols, NCBI Gene, UniProt Isoform, Ensembl and RefSeq, to primary UniProt accession numbers, where possible, and then normalized and merged original protein types to canonical UniProt ones, thus building a larger BioPAX network of all pathways, interactions and participants from different data sources. (pathwaycommons.org)
  • The American Nurses Credentialing Center (ANCC) Pathway to Excellence® (PTE) Program recognizes a health care organization's commitment to creating a positive practice environment that empowers and engages staff. (nursingworld.org)
  • Visit the Pathway website to learn about Pathway and the benefits of a positive practice environment. (nursingworld.org)
  • Frontline staff and leaders are involved in conducting the self- assessment and gap analysis to identify gaps for improvement and celebrate areas where the Pathway Practice Standards are active in the organization's practices, policies and culture. (nursingworld.org)
  • The redesign process typically involves a review of current practice using the patient pathway before considering possible improvements. (bmj.com)
  • Note: to effectively enforce cross-species check, BioSources must have a UnificationXref with "taxonomy" database name and id, and Pathways, ProteinReferences - not empty 'organism' property value). (pathwaycommons.org)
  • Beginning Tuesday, Sept. 5, construction will begin on a new ten-foot-wide multi-modal bike and pedestrian path that will replace the existing four-foot-wide sidewalk on the south side of Dayton Street - running from East Enon Road to Stafford Street. (ysnews.com)
  • Although Burns and Swinger began their efforts three years ago to bring these traffic calming and pedestrian safety measures to fruition, Burns nevertheless sees the multi-modal pathway and bump-outs as a couple ways in which the Village is acknowledging the ongoing local concerns about traffic within the municipality. (ysnews.com)
  • SMART is developing a Pathway Wayfinding Plan that will include signage for the multi-use bicycle and pedestrian pathway, which connects communities to SMART rail stations and other destinations. (sonomamarintrain.org)
  • This pathway converts a C3 metabolite to two acetyl-CoA by fixation of one additional CO2 equivalent, or assimilates glyoxylate, a photorespiration intermediate, to produce acetyl-CoA without net carbon loss. (osti.gov)
  • Molecules that inhibit the cAMP pathway include: cAMP phosphodiesterase converts cAMP into AMP by breaking the phosphodiester bond, in turn reducing the cAMP levels Gi protein, which is a G protein that inhibits adenylyl cyclase, reducing cAMP levels. (wikipedia.org)
  • Based on a "distributed learning model", Pathways enables the College to provide academic courses and training online to students anywhere in the world. (rockymc.edu)
  • All requirements must be maintained through the application phase, the review phase, and designation as a Pathway to Excellence organization. (nursingworld.org)
  • For Pathway purposes, campuses are remote care sites of an applicant organization. (nursingworld.org)
  • How does my organization start our Pathway journey? (nursingworld.org)
  • A stroke pathway allows all healthcare professionals involved in the continuum to ensure a standard of care. (medtronic.com)
  • A Multi-facility healthcare system cannot apply as a whole. (nursingworld.org)
  • This pathway can also be activated downstream by directly activating adenylyl cyclase or PKA. (wikipedia.org)
  • The pathway may also be deactivated downstream by directly inhibiting adenylyl cyclase or dephosphorylating the proteins phosphorylated by PKA. (wikipedia.org)
  • Molecules that activate cAMP pathway include: cholera toxin - increases cAMP levels forskolin - a diterpene natural product that activates adenylyl cyclase caffeine and theophylline inhibit cAMP phosphodiesterase, which degrades cAMP - thus enabling higher levels of cAMP than would otherwise be had. (wikipedia.org)
  • While indole diterpene (IDT) and rarely indole sesquiterpene (IST) pathways have been found individually in filamentous fungi, here we show that both cluster types are encoded within the genome of Tolypocladium album. (bvsalud.org)
  • Exporting to the MSigDB format will enable computational biologists to use pathway commons data within gene set enrichment algorithms, such as GSEA. (pathwaycommons.org)
  • Site Principle Investigator: PROspective Multicenter Imaging Study for Evaluation of Chest Pain (PROMISE) prospective, randomized, multi-center clinical trial:Principle Investigator - Duke E.D. Site - "Speed" Study. (duke.edu)
  • The model will integrate and analyse data from various types of resources vertically ranging from single molecule information, pathway modelling, up to clinical data and patient's response. (europa.eu)
  • Combining generic mechanistic modelling of the biochemical behaviour, accompanied by new generic mining techniques and clinical data integration, will create a multidisciplinary platform prototype suitable for modelling of other cancer related pathways. (europa.eu)
  • Patient pathway for ICM, including transition of care and follow-up plan. (medtronic.com)
  • The patient pathway can serve various roles, and it may be mapped in different ways using a variety of media. (bmj.com)
  • This paper reviews the evolution of the patient pathway comparing the merits of different media. (bmj.com)
  • In addition, the pathway can fulfil new roles as a training tool and an effective basis for organising knowledge about patient care. (bmj.com)
  • 3 An important tool in understanding patients' needs is the patient pathway. (bmj.com)
  • This paper compares the requirements for patient pathway mapping in redesign with the capabilities of different pathway models and demonstrates the benefits of one particular method used in the redesign of Unscheduled Care. (bmj.com)
  • 9 The development of an understanding of a complete system implies a requirement for mapping and communicating patient pathways. (bmj.com)
  • In the field of molecular biology, the cAMP-dependent pathway, also known as the adenylyl cyclase pathway, is a G protein-coupled receptor-triggered signaling cascade used in cell communication. (wikipedia.org)
  • This paper describes how to create realistic energy transition management models: quantitative models that can discover profitable pathways from fossil fuels to renewable energy. (hindawi.com)
  • All participants (corresponding BioPAX EntityReferences) for a pathway must come from the same species as the pathway. (pathwaycommons.org)
  • Participants from cross-species pathways, as well as those for which no identifier is found (i.e., when there're no Xrefs of given type), are removed. (pathwaycommons.org)
  • This course will inform these pathways by placing wellbeing for all species and natural systems at the center and rethinking our social systems independent of economic growth in fields such as work, culture, civil society, governance and decision-making. (lu.se)
  • This leads to an increase in adenylyl cyclase activity, thereby increasing cAMP levels, which can lead to an increase in insulin and therefore hypoglycemia The Gs alpha subunit slowly catalyzes the hydrolysis of GTP to GDP, which in turn deactivates the Gs protein, shutting off the cAMP pathway. (wikipedia.org)
  • There are pathway and bike lane improvements planned in on 24 Avenue NW for the Banff Trail Area Improvements . (livewirecalgary.com)
  • Stay up to date with cycling developments in this bike friendly city with hundreds of kilometres of pathways. (hansonthebike.com)
  • Medtronic can assist your team in the planning and implementation of your stroke pathway. (medtronic.com)
  • Identifying a pathway champion to drive the initiative is critical to ensuring successful implementation. (medtronic.com)
  • Education and communication is crucial to pathway implementation and ongoing success. (medtronic.com)
  • 8,9,10 In addition, implementation of smokefree policies can result in substantial cost savings for multi-unit housing operators and society. (cdc.gov)
  • Establishing a monitoring pathway to detect and treat AF can significantly reduce a patient's risk for another stroke. (medtronic.com)
  • Here, we will restrict our study to the physiological pathway involved in the ability of an animal to detect and react to noxious stimuli that could potentially impair its tegument by escaping away from that stimulus. (frontiersin.org)
  • Educate the entire care team on the cryptogenic stroke pathway (including hospitalists, nurses, Fellows, and PCPs). (medtronic.com)
  • A case in point would be expansion of multi-sectoral & interdisciplinary surveillance cutting across human, animal and environmental interface. (who.int)
  • A stroke pathway, or stroke protocol, is a consistent approach to a follow-up plan and transition of care for patients with an ischemic stroke. (medtronic.com)
  • We developed a multi-phase approach to study grizzly bear movement, habitat use, and population connectivity. (usgs.gov)
  • Vocational skills training for people with intellectual disabilities: A multi-faceted approach. (bvsalud.org)
  • In this context, degrowth aims for a multi-scalar transformation beyond the growth-oriented economic paradigm to achieve socio-ecological sustainability. (lu.se)
  • Using data from a multi-institutional survey, we examined students' reasons for participating and differences across institutions and demographic groups. (ed.gov)
  • The pathway to profitability for marketers will be determined by the ability to integrate mobile, TV and Internet traffic and advertising data into a holistic, effective, multi-strand fabric that blankets the consumer in a traceable, measurable way. (nielsen.com)
  • The evidence-based Pathway Standards provide an essential foundation for creating a culture of sustained excellence-a critical goal for organizations to thrive in this value-based industry and plays a key role in the successful recruitment and retention of high-performing nursing staff. (nursingworld.org)
  • Family Pathways Thrift Stores strives to provide you the best value on donated goods while also raising funds for our community programs and services. (familypathways.org)
  • Pathways for transition of care and follow-up help to ensure these patients receive better care. (medtronic.com)
  • The entire project - of building the multi-modal pathway, installing the five bump-outs and erecting the new sets of rapid-flashing beacons - is scheduled to be completed by May 1, 2024. (ysnews.com)
  • Inspired by a southeast Calgary pathway project that will hopefully still be built this year, Calgarian Jarvis Schmid set about his own advocacy project. (livewirecalgary.com)
  • Schlauch's worked to get the 42 Avenue SE multi-use pathway project to the point where it's scheduled for construction this year. (livewirecalgary.com)
  • Be sure to establish a plan and ownership for key pathway education and communication in your hospital. (medtronic.com)
  • Pathway mapping is often a major element in the deliberations of Plan Do Study Act meetings of local staff, helping them appreciate the whole system when identifying and managing constraints. (bmj.com)
  • Health Joint ction Plan' needs to focus on the pathways and action tracks . (who.int)
  • However, experience in the redesign of Unscheduled Care in NHS Fife suggests that computer-based, hierarchical pathway models using stylised icons offer many advantages. (bmj.com)
  • 8,9 Evidence suggests there is high compliance and support of smokefree building policies among most multi-unit housing residents. (cdc.gov)
  • We elucidate the structure and organisation of this 12-gene cluster, characterise the last two missing pathway steps, and reconstitute the entire pathway in tobacco by transient expression. (cas.cz)
  • Can our entire hospital system apply for Pathway designation? (nursingworld.org)
  • Applicant organizations may include additional campuses as defined by Pathway. (nursingworld.org)
  • The Pathway to Excellence Program® - is the premier designation for healthy work environments and recognizes health care organizations that demonstrate a commitment to establishing the foundation of a healthy workplace for staff. (nursingworld.org)
  • In 2015, standardized care pathways (SCP) were introduced in Sweden, with the objective to shorten waiting times in cancer care. (cancercentrum.se)
  • Urine is analyzed because urinary excretion is the major pathway for eliminating arsenic from the mammalian body (Vahter ME, 1988). (cdc.gov)
  • Thanks to the two adjustable hook and loop fasteners at the back and instep, Pathway can accommodate a variety of foot shapes, ensuring a personalized fit. (feelgrounds.com)
  • A variety of pathway models are available, employing a range of media. (bmj.com)
  • Because Rocky Mountain College is multi-denominational, we can serve the needs of a variety of churches and organizations. (rockymc.edu)
  • Family Pathways Thrift Stores have a variety of the supplies kids need to face the school year. (familypathways.org)
  • We need models that help us to uncover quick and preferably profitable pathways to a renewable energy system [ 3 ]. (hindawi.com)
  • This webinar is aimed at students or early researchers beginning to use bioinformatics resources in their studies/research who wish to learn more about multi-omics pathway analysis and Reactome. (ebi.ac.uk)
  • Where can we learn more about Pathway to Excellence? (nursingworld.org)
  • Rather than replace a video platform, consumers are media multi-tasking on multiple platforms. (nielsen.com)
  • Pathways continues to pursue multiple options both in Canada and internationally. (rockymc.edu)
  • The technique uses various medications that target multiple pain pathways, and generally lessens the need for opioid painkillers. (msdmanuals.com)
  • In this webinar we will discuss how to perform comparative multi-omics pathway analyses using the ReactomeGSA pathway analysis system. (ebi.ac.uk)
  • Results and Conclusions Such approaches can increase the effectiveness of pathways in the redesign process, providing both the detail and the system view in an accessible graphical form. (bmj.com)
  • BioPAX is the default and most complete output format of "Pathway Commons" that offers access to all the details of the biological network model stored in the system. (pathwaycommons.org)
  • Missions' organizations that send people to serve overseas are able to have their missionaries, and the lay leaders they serve alongside, take biblical and theological training through Pathways. (rockymc.edu)
  • That new place and model is "Pathways: Powered by Rocky Mountain College" which was officially launched at the beginning of 2015. (rockymc.edu)
  • Whereas the traditional Bible College model was based on a physical campus, Pathways sends the training to where our students are already in a ministry or vocational setting, and they are seeking to further their education. (rockymc.edu)
  • Pathways is enabling Rocky Mountain College to do that in a new way, to train many more leaders who are committed to building God's kingdom, wherever they serve. (rockymc.edu)
  • This seminar will highlight Metacore Pathway Analysis Platform from Clavariate Cortellis. (wayne.edu)
  • As for tumor invasion and metastasis, carcinoma-associated fibroblasts are able to enhance tumor cells migration and invasion via activating the process of specific pathways. (frontiersin.org)
  • The current study aimed to advance our understanding of tirapazamine-induced lesions and the pathways involved in their repair. (aacrjournals.org)
  • Being the savvy thrifter you are, you know that Family Pathways Thrift Stores can help you make the most of your back-to-school budget. (familypathways.org)
  • Back to school shopping at the Forest Lake Family Pathways Thrift Store. (familypathways.org)
  • Watch clinicians discuss best practices regarding establishing a stroke pathway. (medtronic.com)
  • Watch neurologists and electrophysiologists (Eps) share their best practices in partnering with multi-disciplinary colleagues to establish a stroke pathway at their institutions. (medtronic.com)
  • Our range of irregular Stepping Stones are easy to lay and ideal for creating pathways in your lawn or graveled area. (stratastones.co.uk)
  • If you are looking to spruce up your garden space or give your pathway a striking new appeal, then go for irregular stepping stones that are easy to lay and ideal for creating pathways. (stratastones.co.uk)
  • Clear Track Fiber Pathways offer a clear advantage! (corning.com)
  • The American Pathway Fixed MVA 7 has a full penalty free withdrawal window after 7 years. (annuityadvantage.com)