• The diagnosis is guided by histology and immunohistochemistry. (biomedcentral.com)
  • Using basic histology staining, immunohistochemistry methods, and blood chemistry analysis, we observed profound kidney tissue injury such as glomerular and tubular damage in the experimental group, which were substantially ameliorated by metformin. (bvsalud.org)
  • New insights emerged last decade that enriched our knowledge regarding the biological behavior of appendiceal neuroendocrine tumors (NETs), which range from totally benign tumors less than 1cm to goblet cell carcinomas which behave similarly to colorectal adenocarcinoma. (wjgnet.com)
  • Appendiceal goblet cell carcinoid (GCC) and adenocarcinoma ex-goblet cell carcinoid (AdexGCC) have previously been described as two entities in a spectrum of neoplasms showing both glandular/mucinous and neuroendocrine differentiation [ 1 ]. (gastrores.org)
  • The 5-year DFS per tumor origin was: 96% for perforated low grade appendiceal mucinous neoplasm (LAMN II) and 68.1% for colon origin. (unav.edu)
  • Patients with low-grade appendiceal mucinous carcinomas (LAMNs) treated with cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) have a favorable prognosis. (rare-cancer.org)
  • The 2 most common solid tumors to harbor NRG1 fusions are KRAS wild-type pancreatic adenocarcinoma and non-small cell lung cancer, specifically mucinous adenocarcinoma, Carrizosa says. (onclive.com)
  • Purpose Pancreatic ductal adenocarcinoma (PDAC) has a poor prognosis. (medscape.com)
  • Thirteen individuals with FPC (6.1%) underwent surgical resection for a suspected PRL, but only four (1.9%) had high-risk lesions (ie, high-grade intraductal papillary mucinous neoplasms or grade 3 pancreatic intraepithelial neoplasms). (medscape.com)
  • Aruj Chawla, DO discusses a study that brings about a novel method to analyze vascular involvement in pancreatic ductal adenocarcinomas. (arrs.org)
  • atypical adenomatous hyperplasia and diffuse idiopathic pulmonary neuroendocrine cell hyperplasia. (ersjournals.com)
  • In addition of the categories of squamous dysplasia and carcinoma in situ , two additional lesions were added to the group of pre-invasive lesions: atypical adenomatous hyperplasia (AAH) and diffuse idiopathic pulmonary neuroendocrine cell hyperplasia (DIPNECH). (ersjournals.com)
  • Data queried for this analysis include colorectal adenocarcinoma (2010-2011) from the Surveillance, Epidemiology, and End Results Program (SEER) database. (oncotarget.com)
  • Vascular disorders of the lung: thromboembolism, pulmonary infarction and hemorrhage, pulmonary hypertension (primary and secondary). (unibo.it)
  • As compared to the previous edition, changes include a better definition of pre-invasive lesion, a reclassification of adenocarcinoma, the description of two new tumour types as variants of large cell carcinoma, large cell neuroendocrine carcinoma (LCNEC) and basaloid carcinoma, and a new class called pleomorphic carcinoma. (ersjournals.com)
  • We identified a unique case of triple SLC, including adenocarcinoma, squamous cell carcinoma, and mixed small and large cell neuroendocrine carcinoma, which has poor prognostic implications. (biomedcentral.com)
  • Adenocarcinoma ex-goblet cell carcinoid (AdexGCC) was considered a neuroendocrine adenocarcinoma, despite majority of tumor cells being negative for conventional neuroendocrine markers such as chromogranin and synaptophysin. (gastrores.org)
  • Recently, insulinoma-associated protein 1 (INSM1) has been identified as a novel neuroendocrine marker that is more sensitive than chromogranin, synaptophysin, and CD56 in pulmonary neuroendocrine tumors. (gastrores.org)
  • Non-neoplastic smoke-related lung disease: chronic obstructive pulmonary disease, small airways disease/respiratory bronchiolitis, Langerhans cell histiocytosis of the lung. (unibo.it)
  • This volume is decreased below the expected value in obstructive and restrictive pulmonary diseases. (ehd.org)
  • Collins K , Segura S, Hwang M. Endocrine cell micronests in an ovarian mucinous borderline tumor: a potential diagnostic pitfall for microinvasion. (iu.edu)
  • Daniel Carrizosa, MD, MS, oncologist, Head and Neck Cancer Lung Cancer, Hematology and Medical Oncology (Cancer), Atrium Health Levine Cancer Institute (Thoracic-Pulmonary), discusses the prevalence of NRG1 gene fusions in solid tumors. (onclive.com)
  • Recommendations for the management of subsolid pulmonary nodules detected at CT: a statement from the Fleischner Society. (radiopaedia.org)
  • There are reports of occasional pulmonary tumour thrombotic microangiopathy leading to pulmonary hypertension and coagulation problems that could be successfully treated with Imatinib. (wikipedia.org)
  • Stomach cancers with both adenocarcinoma and some SRC (known as mixed-SRCC) exhibit more aggressive behavior than purely SRCC or non-SRCC histologies. (wikipedia.org)
  • Mohs surgery is a surgical technique used to treat various skin cancers that allows precise microscopic control of the margins by utilizing tangentially cut frozen-section histology. (medscape.com)
  • Non-small cell lung cancer (NSCLC) represents a heterogeneous group of lung cancers that do not have "small cells" on histology. (radiopaedia.org)
  • He had recently been diagnosed with adenocarcinoma in the right upper lobe, with a poorly differentiated carcinoma favoring squamous cell cancer based on bronchoalveolar lavage of the right lower lobe for which treatment was started. (biomedcentral.com)
  • Poorly differentiated histology. (cancer.gov)
  • Mismatch repair deficiency occurs in 5% to 10% of patients with rectal adenocarcinomas. (cancer.gov)
  • Salivary Gland Polymorphous Adenocarcinoma: Clinicopathological Features and Gene Alterations in 36 Japanese Patients. (nagoya-u.ac.jp)
  • International association for the study of lung cancer/american thoracic society/european respiratory society international multidisciplinary classification of lung adenocarcinoma. (radiopaedia.org)
  • Haemoperitoneum seen at laparotomy suggested a diagnosis of ectopic pregnancy .The diagnosis of ruptured corpus luteum cyst (RCLC) was made only after histology. (bvsalud.org)
  • Fifty-four cases (41.9%) had histologically normal appendices, while 75 cases (58.1%) had various histopathologically demonstrable lesions ranging from acute appendicitis (the most frequent with 27%) to neoplasia (one case of mucinous adenocarcinoma). (bvsalud.org)
  • Full knowledge of normal anatomy, histology and embriology are necessary to understand Anatomic Pathology. (unibo.it)
  • Adenopathy, hepatomegaly, or pulmonary signs may be present with metastatic disease. (cancer.gov)
  • Some are of different histological subtypes (including the category extremely rare occurrences (and will normally have been `flagged' `uncertain histology') within the total of morphologically verified as such by some verification procedure within the registry or at cases for the particular ICD category. (who.int)
  • Recent research has also revealed clinical, radiologic, and pathologic correlates, leading to greater knowledge in molecular profiling and targeted therapeutics, as well as an emphasis on the rising incidence of adenocarcinoma histology. (scienceopen.com)
  • Although meningiomas commonly arise in locations where meningothelial cells are found, the embryonic origin of intraventricular and pulmonary meningiomas are intriguing. (medscape.com)
  • Many studies now justify that AAH is a precursor to adenocarcinoma 4 - 14 . (ersjournals.com)
  • This is in keeping with ultrastructural studies in GCCs that showed the presence of abundant mucinous vacuoles, in comparison with the extremely difficult to locate, occasional membrane-bound, electron-dense granules [ 3 ]. (gastrores.org)