Mtor inhibition induces upstream receptor tyrosine kinase. Medical search. Frequent questions

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Anatomy13

Cell Line, Tumor Cell Line Cells, Cultured 3T3 Cells Tumor Cells, Cultured COS Cells Cell Membrane PC12 Cells NIH 3T3 Cells Fibroblasts CHO Cells Cell Line, Transformed Neurons

Organisms8

Mice, Nude Mice, Knockout Mice, Inbred C57BL Cricetinae Mice, Transgenic Cercopithecus aethiops Rats, Sprague-Dawley Drosophila

Diseases6

Cell Transformation, Neoplastic Disease Models, Animal Lung Neoplasms Neoplasms Breast Neoplasms Neovascularization, Pathologic

Chemicals and Drugs167

TOR Serine-Threonine Kinases Receptor Protein-Tyrosine Kinases Tyrosine Sirolimus Protein Kinase Inhibitors Protein-Tyrosine Kinases Protein Kinases Phosphatidylinositol 3-Kinases Receptor, Epidermal Growth Factor Proto-Oncogene Proteins c-akt Protein-Serine-Threonine Kinases Ribosomal Protein S6 Kinases, 70-kDa Proto-Oncogene Proteins src-Family Kinases Phosphotyrosine Proto-Oncogene Proteins c-met Antineoplastic Agents Receptor Tyrosine Kinase-like Orphan Receptors Protein Tyrosine Phosphatases Proto-Oncogene Proteins c-kit Receptors, Eph Family Receptor, EphA2 Intracellular Signaling Peptides and Proteins Quinazolines Calcium-Calmodulin-Dependent Protein Kinases Pyrimidines Receptor, EphB2 Phosphoproteins Enzyme Inhibitors Adaptor Proteins, Signal Transducing Antibiotics, Antineoplastic fms-Like Tyrosine Kinase 3 Receptor, EphA4 Proto-Oncogene Proteins c-ret Receptor, EphB4 PTEN Phosphohydrolase Mitogen-Activated Protein Kinase 1 Epidermal Growth Factor Tyrphostins Ephrin-A1 Receptor, Insulin Morpholines Receptor, erbB-2 Mitogen-Activated Protein Kinases Genistein Receptors, Platelet-Derived Growth Factor Receptor, TIE-2 Protein Kinase C Recombinant Fusion Proteins Receptor, trkA Multiprotein Complexes Mitogen-Activated Protein Kinase 3 Indoles Ephrins Proteins Benzamides RNA, Small Interfering Proto-Oncogene Proteins pp60(c-src)Piperazines Ephrin-B1 Hepatocyte Growth Factor Receptor, erbB-3 Proto-Oncogene Proteins c-abl Receptors, Growth Factor Ephrin-B2 Receptor, Platelet-Derived Growth Factor beta Quinolines Immunosuppressive Agents GRB2 Adaptor Protein Eukaryotic Initiation Factor-4E Receptor, EphA1 Recombinant Proteins Receptors, Vascular Endothelial Growth Factor Lymphocyte Specific Protein Tyrosine Kinase p56(lck)Ligands Receptors, TIE Oncogene Proteins Mitogen-Activated Protein Kinase Kinases Receptor, TIE-1 Pyrroles Tyrosine 3-Monooxygenase p38 Mitogen-Activated Protein Kinases Extracellular Signal-Regulated MAP Kinases RNA, Messenger Proto-Oncogene Proteins c-fyn Protein Tyrosine Phosphatase, Non-Receptor Type 11 Shc Signaling Adaptor Proteins Membrane Proteins Phosphotransferases (Alcohol Group Acceptor)Proto-Oncogene Proteins c-cbl Cyclic AMP-Dependent Protein Kinases Ephrin-A2 Receptors, Cell Surface Receptors, Mitogen Ribosomal Protein S6 Kinases Focal Adhesion Protein-Tyrosine Kinases Janus Kinase 2 Drosophila Proteins JNK Mitogen-Activated Protein Kinases Vanadates Phospholipase C gamma Receptor, trkB Receptor, EphB6 Receptor, EphA3 Focal Adhesion Kinase 1 Receptor, IGF Type 1 Neuregulins Isoenzymes Focal Adhesion Kinase 2 Receptor, EphB3 p21-Activated Kinases Receptors, Fibroblast Growth Factor ras Proteins Type C Phospholipases Platelet-Derived Growth Factor Vascular Endothelial Growth Factor Receptor-2 Oncogene Proteins v-erbB MAP Kinase Kinase 1 Glial Cell Line-Derived Neurotrophic Factor Receptors Lactams, Macrocyclic Ephrin-A4 DNA Primers Nerve Growth Factors Protein Tyrosine Phosphatase, Non-Receptor Type 1 Receptor, Platelet-Derived Growth Factor alpha DNA, Complementary Protein Tyrosine Phosphatase, Non-Receptor Type 6 Pyridines Benzoquinones Neuregulin-1 Quinones Carrier Proteins MAP Kinase Kinase Kinases DNA-Binding Proteins Glial Cell Line-Derived Neurotrophic Factor Stem Cell Factor Insulin Nerve Tissue Proteins Nitriles Angiopoietin-1 Intercellular Signaling Peptides and Proteins Ephrin-A3 CDC2 Protein Kinase Receptor, Macrophage Colony-Stimulating Factor Adaptor Proteins, Vesicular Transport Chromones Androstadienes Glycogen Synthase Kinase 3 Receptors, Nerve Growth Factor Transcription Factors Phenylurea Compounds Calcium Cyclin-Dependent Kinases Phthalazines Proto-Oncogene Proteins c-crk Antibodies, Monoclonal Receptor, EphB1 Receptor, Fibroblast Growth Factor, Type 1 Angiogenesis Inhibitors Creatine Kinase Oncogene Protein v-cbl Fusion Proteins, bcr-abl Insulin Receptor Substrate Proteins Vascular Endothelial Growth Factor A Ephrin-A5 Serine Casein Kinase II

Analytical, Diagnostic and Therapeutic Techniques and Equipment14

Blotting, Western Transfection Xenograft Model Antitumor Assays Molecular Targeted Therapy Precipitin Tests Immunoblotting Models, Biological Disease Models, Animal Mutagenesis, Site-Directed Immunohistochemistry Cloning, Molecular Reverse Transcriptase Polymerase Chain Reaction Models, Molecular Immunoprecipitation

Phenomena and Processes44

Signal Transduction Phosphorylation Enzyme Activation Cell Proliferation MAP Kinase Signaling System Amino Acid Sequence Mutation Protein Binding Apoptosis Transfection src Homology Domains Protein Structure, Tertiary Cell Survival Autophagy Drug Resistance, Neoplasm Base Sequence Cell Division Cell Movement Binding Sites Kinetics Drug Synergism Sequence Homology, Amino Acid Down-Regulation Dose-Response Relationship, Drug Gene Expression Substrate Specificity Cell Differentiation Time Factors Gene Expression Regulation, Neoplastic Genes, erbB Gene Expression Regulation Cell Adhesion Dimerization Protein Processing, Post-Translational Gene Expression Regulation, Enzymologic Gene Expression Regulation, Developmental Protein Transport Up-Regulation Structure-Activity Relationship Cell Cycle Genes, src Point Mutation Receptor Cross-Talk Phenotype

Disciplines and Occupations1

Immunohistochemistry

Information Science3

Molecular Sequence Data Amino Acid Sequence Base Sequence

Anatomy Organisms Diseases Chemicals and Drugs Analytical, Diagnostic and Therapeutic Techniques and Equipment Phenomena and Processes Disciplines and Occupations Information Science

TOR Serine-Threonine Kinases Receptor Protein-Tyrosine Kinases Tyrosine Sirolimus Signal Transduction Protein Kinase Inhibitors Phosphorylation Protein-Tyrosine Kinases Protein Kinases Phosphatidylinositol 3-Kinases Receptor, Epidermal Growth Factor Cell Line, Tumor Proto-Oncogene Proteins c-akt Protein-Serine-Threonine Kinases Ribosomal Protein S6 Kinases, 70-kDa Proto-Oncogene Proteins Enzyme Activation src-Family Kinases Phosphotyrosine Cell Proliferation MAP Kinase Signaling System Proto-Oncogene Proteins c-met Antineoplastic Agents Receptor Tyrosine Kinase-like Orphan Receptors Protein Tyrosine Phosphatases Molecular Sequence Data Cell Line Proto-Oncogene Proteins c-kit Receptors, Eph Family Receptor, EphA2 Intracellular Signaling Peptides and Proteins Amino Acid Sequence Cells, Cultured Quinazolines Blotting, Western Calcium-Calmodulin-Dependent Protein Kinases Mutation Pyrimidines Receptor, EphB2 Phosphoproteins Protein Binding Apoptosis Transfection Enzyme Inhibitors Adaptor Proteins, Signal Transducing Antibiotics, Antineoplastic fms-Like Tyrosine Kinase 3 Xenograft Model Antitumor Assays Receptor, EphA4 Proto-Oncogene Proteins c-ret Mice, Nude src Homology Domains Receptor, EphB4 PTEN Phosphohydrolase 3T3 Cells Mitogen-Activated Protein Kinase 1 Protein Structure, Tertiary Cell Survival Epidermal Growth Factor Tyrphostins Ephrin-A1 Receptor, Insulin Morpholines Receptor, erbB-2 Mitogen-Activated Protein Kinases Genistein Autophagy Drug Resistance, Neoplasm Receptors, Platelet-Derived Growth Factor Receptor, TIE-2 Protein Kinase C Recombinant Fusion Proteins Base Sequence Receptor, trkA Multiprotein Complexes Molecular Targeted Therapy Mitogen-Activated Protein Kinase 3 Tumor Cells, Cultured Cell Division Indoles Ephrins Proteins Benzamides RNA, Small Interfering Proto-Oncogene Proteins pp60(c-src)Piperazines Ephrin-B1 Hepatocyte Growth Factor Receptor, erbB-3 Proto-Oncogene Proteins c-abl Receptors, Growth Factor Ephrin-B2 Receptor, Platelet-Derived Growth Factor beta Quinolines Immunosuppressive Agents Precipitin Tests GRB2 Adaptor Protein Eukaryotic Initiation Factor-4E Receptor, EphA1 Cell Movement

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