Loading...
  • mutation
  • A subtle mutation affecting the epigenome - a set of dynamic factors that influence gene activity - may lead to an inherited form of mental retardation that affects boys, find researchers at Children's Hospital Boston. (medicalnewstoday.com)
  • neuronal
  • The Sonic-hedgehog-controlled cascade may diverge from the Wnt1-regulated network at later stages of neural development through induction of proneural transcription factors required for the acquisition of generic neuronal properties by the midbrain dopaminergic progeny. (tum.de)
  • mice
  • The basic findings in mice revealed critical factors that determine the fate of one type of nerve cell progenitor and that set bone marrow stem cells into action. (bio-medicine.org)
  • Function
  • Ventx factors function as Nanog-like guardians of developmental potential in Xenopus. (nih.gov)
  • These data support a novel function of Msx1 and Msx2 as transcriptional activators. (biologists.org)
  • involvement
  • Although malformation of the SCO during gestation leads to ventricular dilation and aqueductal stenosis before birth (FIGURE 1, B AND C ⇓ ) ( 32 , 80 ), the involvement of specific factors has been slowly elucidated over the past decade through the analysis of mutant mouse models. (physiology.org)
  • However
  • 24 However, because calcium phosphate mineral deposition itself elicits inflammatory responses, 25 including tumor necrosis factor (TNF) production by macrophages, 26,27 a primary role for inflammation in the pathogenesis of clinically relevant vascular calcification was unproven until very recently. (ahajournals.org)
  • However, it is clear that environmental factors are also important. (frontiersin.org)
  • development
  • The cerebral spinal fluid (CSF) flow tract is a vital lifeline for supplying the brain with essential nutrients and growth factors throughout development and into adulthood. (physiology.org)
  • Author information Abstract Signaling by transforming growth factor (TGF)-β plays an important role in development, including in palatogenesis. (edu.au)
  • Li Z, Xu Z, Duan C, Liu W, Sun J, Han B. Role of TCF/LEF Transcription Factors in Bone Development and Osteogenesis. (medsci.org)
  • study
  • Our study provides new insights into the transcriptional control of spinal cord patterning by BMP signaling, with Msx1 and Msx2 acting upstream of Atoh1. (biologists.org)