These capped RNA fragments can then be transferred to L protein, to be further trimmed in length by the endonuclease and used by the RdRp to initiate viral mRNA synthesis. (wikipedia.org)
L-RNA (8,917 nucleotides) contained a single open reading frame (ORF) in the viral complementary (vc) strand and encoded a 330-kDa protein. (esciencepress.net)
and another in the viral complementary sense, encoding the viral nucleocapsid protein of 28.8-kDa Mr. Amino acid sequences of TSWV-KP of S-RNA NSs and N exhibited 35.9-87.9% and 19.9-98.4% identity, respectively. (esciencepress.net)
computer simulations of proteolysis of marburg and ebola-zaire filovirus coded proteins to generate nonapeptides with motifs of known hla class i haplotypes and detection of antigenic domains in the viral glycoproteins. (liverpool.ac.uk)
Proteins associated with the inner surface of the lipid bilayer of the viral envelope. (lookformedical.com)
These proteins have been implicated in control of viral transcription and may possibly serve as the "glue" that binds the nucleocapsid to the appropriate membrane site during viral budding from the host cell. (lookformedical.com)
Genome3
The tri-segmented genome includes a S (small), M (medium), and L (large) segment that code for nucleocapsid (N), glycoproteins G1 and G2, and L protein respectively. (wikipedia.org)
Bunyaviridae: Genome organization and replication strategies. (esciencepress.net)
The genome encodes for the typical five proteins found in all rhabdoviruses: nucleocapsid (N), phosphoprotein (P), matrix (M), glycoprotein (G), and polymerase (L). However, there are three additional genes, U1-U3, that encode for proteins of unknown function. (wikimili.com)
Replication1
The L protein encoded by the L segment possesses enzymatic functions that are involved within transcription and replication. (wikipedia.org)
Virion2
By a process called pH-dependent fusion between the virion and the endosomal membrane, nucleocapsids enter the cytoplasm. (wikipedia.org)
While M segment mRNAs are translated by membrane-bound ribosomes, L and S segment mRNAs are translated by free ribosomes. (wikipedia.org)
Sequences1
the primary amino acid sequences of the proteins coded by marburg and ebola-zaire filoviruses were studied by computer programs to search for putative proteolytic cleavages which yield nonapeptides with motifs of binding to known hla class i haplotypes. (liverpool.ac.uk)
Once the nucleocapsids are released, RdRp initiates transcription by binding to the encapsidated segments. (wikipedia.org)
Found2
optimal dilutions of specific immunoglobulin (1:500, corresponding to protein concentration of 50 micrograms/ml) and conjugate were found. (liverpool.ac.uk)
The S segment of the Andes virus contains 1876 nucleotides in total, while encoding a 547 nucleotide-long N protein. (wikipedia.org)
When expressed, the M segment generates the glycoprotein precursor (GPC) which can be cleaved into the envelope Gn and Gc proteins. (wikipedia.org)
While M segment mRNAs are translated by membrane-bound ribosomes, L and S segment mRNAs are translated by free ribosomes. (wikipedia.org)
The L segment of CCHFV comprises approximately 12 kb and contains a single open reading frame encoding a protein almost 4000 amino acids long or 448 kDa. (medscape.com)
Interestingly, the CCHFV L segment sequence is quite distinct from those of other members of the Bunyaviridae family, indicating that this virus family lacks a common ancestor. (medscape.com)
The atypically large size of the CCHFV L segment, together with the recently identified OTU domain in the N-terminal region of the segment, suggests that the L protein may be processed in an autocatalytical manner. (medscape.com)
In this study, we show that Andes hantavirus (ANDV) SmRNA encodes an NSs protein. (nih.gov)
Large1
Modern mass spectrometry (MS) technologies have provided a versatile platform that can be combined with a large number of techniques to analyze protein structure and dynamics. (bvsalud.org)