Loading...
  • Binds
  • The sites phosphorylated in vivo are clustered at the carboxyl terminus, and the phosphorylated region of S6 is thought to lie within the cleft where mRNA binds, a location compatible with a role in the regulation of translation ( 15 ). (pnas.org)
  • antisense
  • In this study we report the existence of an RNA carrying sequences that are complementary (antisense) to the entire coding (sense) region of L7 mRNA. (semanticscholar.org)
  • The more potent X-chromosomal insertion was used in all other experiments shown in this figure (D, F, G, and I). (C and D) In situ hybridization with an antisense Dref mRNA probe (see panel A) shows that induction of DREF RNAi in the posterior part of the third instar larval wing disc by enGal4 decreased the levels of endogenous Dref mRNA. (nih.gov)
  • vitro
  • In summary, this study suggests that the dsRNA-specific chemically modified PNA stimulate -1 RF in a model mRNA hairpin (from 2% to 32%), demonstrated by using cell-free in vitro translation assays. (ntu.edu.sg)
  • control
  • Human ribosomal protein L7 has been shown to be involved in the control of translation of distinct mRNAs. (semanticscholar.org)
  • Ambient protein levels are under coordinated control of transcription, mRNA translation, and degradation. (asnjournals.org)
  • Furthermore, brat overexpressing cells contain less ribosomal RNA than control cells. (biologists.org)
  • B) Expression levels of Dref mRNA in the two DREF knockdown lines were measured by semiquantitative RT-PCR using primers as indicated in panel A. Expression of DREF RNAi was induced ubiquitously under the control of T80Gal4 driver, and total mRNA prepared from third instar whole larval lysates was used to quantify endogenous Dref mRNA level. (nih.gov)
  • thus
  • Thus, we performed a comprehensive detection of terminal oligo-pyrimidine (TOP), which is one of the well-characterized cis-regulatory motifs for translational controls located immediately downstream of the transcriptional start sites of mRNAs. (semanticscholar.org)
  • amino
  • Finally, transfer RNA carries nucleotides and a single amino acid, allowing it to read the code carried by mRNA and respond with the appropriate amino acid for each part of the chain. (reference.com)
  • region
  • A) Schematic of the genomic region of Dref depicting primers used for RT-PCR and the fragments used as hybridization probe to detect endogenous Dref mRNA and to produce the DREF RNAi construct. (nih.gov)
  • development
  • Considering that mRNA translation plays an important role in cell growth, development, malignancy, apoptosis, and response to stress, its study should provide novel insights in renal physiology and pathology. (asnjournals.org)