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  • targets
  • We are currently examining the mechanism by which miR-122 helps HCV RNA replication and are searching for cellular targets of miR-122 and their regulation by miR-122. (stanford.edu)
  • translational
  • Post-transcriptional modifications (alternative splicing and nuclear RNA editing) and post-translational modifications (glycosylation, phoshorylation) result in a very large number of permutations, fine-tuning the kinetic properties of AMPARs (1). (cellsignal.com)
  • Replication
  • Specifically, we have found that miR-122 interacts with the 5' end of the viral RNA and is essential for viral replication. (stanford.edu)
  • interference
  • In situ hybridization analyses of Atwox4-RNA interference plants revealed delayed and reduced expression of both the phloem developmental marker ALTERED PHLOEM1 and HOMEOBOX GENE8 , a marker of the vascular procambium. (plantphysiol.org)
  • bind
  • Indeed, some of such mRNAs with long leaders contain internal ribosome entry sites which can bind ribosomes directly. (stanford.edu)
  • expression
  • A Student t test was used to make comparisons between mRNA expression levels in anti-miR and scrambled oligonucleotide-treated cells. (ahajournals.org)
  • HMGA1 is regulated by Fra-1 in ESCC, and the HMGA1 expression is significantly associated with a poor prognosis in ESCC patients. (springer.com)
  • Angel P, Karin M. Specific members of the Jun protein family regulate collagenase expression in response to various extracellular stimuli. (springer.com)
  • generate
  • Theoretically, the mere existence of a miRNA recognition sequence on a given mRNA is sufficient to generate a functional response. (ehu.es)
  • posttranscriptional
  • Microarray technologies assessing global mRNA levels in cells are only partially valid because posttranscriptional mechanisms dramatically affect protein levels in the proteome. (jimmunol.org)
  • hepatitis
  • Recently, microRNAs have been demonstrated a role in various cancers, immunological conditions, metabolic disorders as well as viral infections, such as human immunodeficiency virus (HIV) infection, cytomegalovirus (CMV) infection and hepatitis C (HCV) infection. (technologynetworks.com)