AnatomyOrganismsChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPhenomena and ProcessesInformation Science
Transcription, GeneticBase SequenceBunyaviridaeRNA, ViralRNA, MessengerRNATranscription FactorsNucleic Acid HybridizationDNARNA, RibosomalRNA, Small InterferingMolecular Sequence DataDNA-Directed RNA PolymerasesBunyamwera virusRNA, BacterialRNA SplicingEncephalitis Virus, CaliforniaRNA EditingRNA Polymerase IIAmino Acid SequencePromoter Regions, GeneticGene Expression RegulationCell LineNucleic Acid ConformationHemorrhagic Fever Virus, Crimean-CongoRNA InterferenceMutationRNA, Double-StrandedCloning, MolecularRNA, TransferBinding SitesProtein BindingCell NucleusRNA Polymerase IIIRNA, Spliced LeaderPlasmidsHeLa CellsRNA VirusesTransfectionRNA Polymerase IProtein BiosynthesisEscherichia coliRNA, UntranslatedRNA StabilityRNA, Small NuclearDNA-Binding ProteinsRNA CapsNuclear ProteinsRNA, FungalCells, CulturedRNA, CatalyticVirus ReplicationSp1 Transcription FactorRNA, AntisenseRNA FoldingTemplates, GeneticRNA-Binding ProteinsReverse Transcriptase Polymerase Chain ReactionGene Expression Regulation, ViralGenesKineticsBlotting, NorthernTranscriptional ActivationEuglena gracilisTrans-ActivatorsGene Transfer TechniquesRNA, Transfer, ValRNA HelicasesCell NucleolusRNA PrecursorsMurine hepatitis virusRepressor ProteinsAmanitinsGenome, ViralRegulatory Sequences, Nucleic AcidRNA, Ribosomal, 5SRNA, Transfer, AlaTranscription Initiation SitePol1 Transcription Initiation Complex ProteinsSignal TransductionRNA Processing, Post-TranscriptionalGene Expression Regulation, BacterialDNA, ViralDNA, ComplementaryCell-Free SystemRNA, PlantOperonSequence Analysis, RNARibonucleoproteinsPoly ADactinomycinTerminator Regions, GeneticChromatinRNA, NeoplasmGenes, ReporterHistonesDNA Restriction EnzymesSaccharomyces cerevisiaeGene Expression Regulation, DevelopmentalTime Factors
NucleotidesPolymeraseRIBONUCLEIC ACIDRibosomesSingle-strandedUracilTRNAProteinAmino acidsMicroRNAsEnzymeCodonProteinsGenesMoleculeTranscriptRibonucleotidesGeneGenomeMolecularReplicationSegmentExtractionStrandBasesComponentsGeneticLevelsPrimaryProcessesNuclearRegulationExpressionFactorsTemplateDomainsCell linesCancer
Nucleotides3
  • adenine (A) - A nitrogenous base that occurs in DNA and RNA nucleotides and pairs with thymine (in DNA) or uracil (in RNA) through two hydrogen bonds. (rcsb.org)
  • 1.Genetic code is the relationship between the sequence of nucleotides on mRNA and the sequence of amino acids in the polypeptide. (infinitylearn.com)
  • The genetic information of life on Earth have been conserved in natural nucleotides-A, G, C, T(U) forming two exclusive sets of base pairs A-T(U) & G-C, that complementing to the fundamental processes of DNA replication & RNA transcription by several polymerases and translation to functional proteins via ribosomal reactions. (fortuneonline.org)
Polymerase3
  • Effects Evaluation of CDCA3 expression in OSCC derived cell lines and main OSCCs To investigate mRNA and protein expression of CDCA3 recognized being a cancer connected gene pop over to this site in our earlier microarray information, we carried out actual time quantita tive reverse transcriptase polymerase chain response and Western blot analyses applying 6 OSCC derived cell lines and major cultured human regular oral keratinocytes. (tcr-signal.com)
  • Once these are added we will add in the synthesis of key macromolecular components (ribosome, RNA polymerase, etc.) and show how they are coupled to their respective reactions. (readthedocs.io)
  • RNA dependent RNA polymerase (RdRp) sequence of RaTG13 shows that it is 100% similar to that of bat corona virus BtCoV/4991 and 98.7-98.9% similar to SARS-CoV-2 RdRp 2 . (preprints.org)
RIBONUCLEIC ACID1
Ribosomes2
  • While RNA makes up most of the composition of bacterial and cytosolic eukaryotic ribosomes, mammalian mitochondrial ribosomes present a more elaborate protein shell, which aids coping with the oxidative microenvironment. (nature.com)
  • Some regions of the genome encode non-protein-coding RNA like transfer RNAs, the RNA components of ribosomes, microRNAs and small interfering RNAs that regulate translation. (cilecenter.org)
Single-stranded4
  • Base-pair (bp) is used to quantitate the length of nucleic acids but it should really be used for DNA only since RNA is single-stranded. (tripod.com)
  • these form the preinitiation complex, which with RNA poly II bind to and read single stranded DNA gene template. (flashcardmachine.com)
  • is a DNA poly enzyme that transcribes single stranded RNA into double stranded DNA. (flashcardmachine.com)
  • Transcript evaluation Complete RNA was isolated from fresh blood with QIAamp RNA blood kit, and single stranded cDNA was synthesized together with the GoScript reverse transcription procedure in ac cordance using the companies directions. (mirnainhibitors.com)
Uracil1
TRNA2
  • This molecule called tRNA, then called sRNA (soluble RNA). (infinitylearn.com)
  • Depending on the organism and availability, mt-tRNA Val or mt-tRNA Phe are incorporated, most likely due to their genomic proximity to mt-rRNA genes and consequent near stoichiometric presence of their transcripts 4 , 8 . (nature.com)
Protein5
  • 40535) Transcription factor TFIIB cyclin-related protein CP001857 CDS Arcpr_0047 complement(40887. (go.jp)
  • Interestingly, real-time PCR and translation inhibition studies revealed that survivin was over-expressed partially through the up-regulation of protein translation instead of gene transcription in A549 cancer cells. (biomedcentral.com)
  • Studies on rodent UGT genes have demonstrated that the transcription factors hepatocyte nuclear factor 1 (HNF1) and CAAT-enhancer binding protein are important positive regulators of UGT expression in the liver (Hansen et al. (aspetjournals.org)
  • Taxonomic classification of those E. ictaluri specific phages must rely on a synthesis of morphological and genomic details, taking into consideration that phage evolution continues to be profoundly directed by lateral gene transfer, and that a rational hierarchical technique of phage classification really should be based within the degree of DNA and protein sequence identity for several genetic loci. (hivprotease-signal.com)
  • 2014). Where annotations were not present or were different, the online Softberry server (http://linux1.softberry.com/berry.phtml) was used to predict mRNA and protein sequences using the FGNESH+ prediction algorithm (Solovyev et al. (molquest.com)
Amino acids3
  • i)The order and sequence of amino acids are defined by the sequence of bases in the mRNA. (infinitylearn.com)
  • The review also outlines the vast applications of UBPs as novel information storage components as well as in creation of semi-synthetic organisms expressing non canonical amino acids, high affinity aptamer generation, PCR based diagnostics and sitespecific labelling of RNAs. (fortuneonline.org)
  • What sequence of amino acids would the following RNA sequence code for if it were to be translated by the ribosome? (migzmediagroup.com)
MicroRNAs1
  • Gene set enrichment analysis of microRNAs showed significant changes in the top six enriched functions that consisted of biological pathway, biological process, molecular function, cellular component, site of expression and transcription factor in all the groups. (researchsquare.com)
Enzyme2
  • Moreover, our recent transcriptomic analysis reveals a decline in mRNA levels of Cyp17a1 , encoding a steroidogenic enzyme, in 4- to 30-day cultures of 6 d pp mouse testes ( 10 ). (elifesciences.org)
  • iv)Severo Ochoa enzyme (polynucleotide phosphoryiase) was also helpful in polymerising RNA with defined sequences in a template independent manner (enzyme synthesis of RNA). (infinitylearn.com)
Codon1
Proteins3
  • Transcription is regulated by proteins called sigma factors. (tcr-signal.com)
  • The heterochromatin-enriched HP1 proteins play a critical role in regulation of transcription. (cipsm.de)
  • These findings culminated in the central dogma of molecular biology, that proteins are translated from RNA, which is transcribed from DNA. (addgene.org)
Genes3
  • As of the July 2013, the total number of genes (including pseudogenes and non-coding RNA genes) is around 58,000 with the total number of transcripts reaching almost 200,000 ( Gencode ). (tripod.com)
  • As a key transcription factor of the Wnt/β-catenin pathway, LEF1 helps to regulate important genes involved in tumor cell death mechanisms. (oncotarget.com)
  • The aim of this study was to compare the in vivo expression of virulence and metabolic genes of S. aureus in a prosthetic joint infection in a human subject with growth in vitro as reference using RNA sequencing (RNA-seq). (biomedcentral.com)
Molecule2
  • Expression evaluation indicated that each transcription and translation goods of this molecule have been hugely expressed in OSCC derived cell lines. (tcr-signal.com)
  • Is a RNA molecule thats shape allows it to catalyze a chemical reaction. (flashcardmachine.com)
Transcript1
  • We hypothesized that the non-coding RNAs transcript may serve as susceptibility to disease biomarkers by smoking and vaping. (researchsquare.com)
Ribonucleotides3
  • What catalyzes the formation of phospho-diester bonds between adjacent ribonucleotides during transcription. (flashcardmachine.com)
  • During transcription the cell was incubated in a solution containing deoxyribonucleotides that weigh 2 units (normal) each and ribonucleotides that weigh 3 units (due to other unusual isotopes) each. (flashcardmachine.com)
  • As other RNA classes, mt-rRNAs contain modified ribonucleotides which are post-transcriptionally introduced by a set of enzymes. (nature.com)
Gene4
  • Southern and Northern blots and reverse-transcription PCR analyses indicate that the same rhodopsin gene is expressed in the retina and the brain but not in the pineal organ of ayu. (bioone.org)
  • For 1 with the tamoxifen treated animals, no tumors selelck kinase inhibitor were observed in the finish from the study and for an additional two animals the remaining tumor was as well modest for RNA extraction, leaving a representative choice of 9 tumors from five tamoxifen treated animals for gene expression analyses. (tcr-signal.com)
  • The geometric suggest with the SRC 1 mRNA ranges relative to the house trying to keep gene TBP in tamoxifen taken care of tumors was 1. (tcr-signal.com)
  • Although they can be found in archaea and eukaryotes, they play the most significant biological role in bacteria where they can be passed from one bacterium to another by a type of horizontal gene transfer (conjugation), usually providing a benefit to the host, such as antibiotic resistance. (addgene.org)
Genome3
  • Expression of this genome entails several, highly regulated processes, with newly synthesised transcripts being cleaved, chemically modified, polyadenylated and further matured in neighbouring structures known as mitochondrial RNA granules (MRGs). (nature.com)
  • While the RNA components of the mitoribosome are mitochondrially-encoded, all MRPs and assembly factors are encoded in the nuclear genome, thus requiring coordination between two genomes for the assembly of these macromolecular complexes. (nature.com)
  • The genome of RaTG13 (MN996532.1) was sequenced from the RNA of a bat faecal swab collected in 2013 from Yunnan, China, however the exact location is not mentioned. (preprints.org)
Molecular1
Replication2
  • The review describes the efficient replication, transcription and translation of Unnatural Base Pairs (UBPs) highlighting the possibility of the expanded genetic alphabets. (fortuneonline.org)
  • But N. equitans possesses most of the DNA repair enzymes and the complete genetic machinery necessary for transcription, translation and DNA replication. (biomedcentral.com)
Segment1
  • Consider the following portion of mRNA produced by the normal order of DNA nucleotide: 5'-ACA-UCA-CGG-GUA-3' What happens if the A is removed from the beginning of the mRNA segment? (migzmediagroup.com)
Extraction1
  • 0 through the remedy time period whereas the handle animals experienced a steady maximize also in tumor amount mRNA expression of SRCs, HER development factor receptors, ER and Ets 2 Tumors as well smaller for RNA extraction according to proto col needed to be excluded from even more analyses. (tcr-signal.com)
Strand1
Bases1
  • But, a permuta tion combination of 4 3 (4x 4×4) would generate 64 codons, generating many more codons than required (ii)Har Gobind Khorana could synthesise RNA molecules with defined combinations of bases (homopolymers and copolymers). (infinitylearn.com)
Components1
  • Amplicon sequencing was used for detection of bacteria in fluid obtained by sonication of prosthesis components (all joint fluid was used for RNA-seq). (biomedcentral.com)
Genetic2
Levels3
  • We then mea sured the CDCA3 mRNA expression levels in principal OSCCs and paired ordinary oral tissues from 69 patients. (tcr-signal.com)
  • Cell density regulates prolyl 4-hydroxylase activity independent of mRNA levels. (embl.de)
  • In contrast, mRNA levels are now shown not to change by both Northern and RNAse protection assays. (embl.de)
Primary1
  • Similar towards the information from your OSCC derived cell lines, qRT PCR analysis showed that CDCA3 mRNA expression was up regulated in 51 of 69 primary OSCCs compared with all the matched regular oral tissues. (tcr-signal.com)
Processes1
  • Many cellular processes, including ribosome biogenesis, are regulated through post-transcriptional RNA modifications. (nature.com)
Nuclear1
  • Here, we characterized the staphylococcal transcriptome in vivo and the joint fluid metabolome in a prosthetic joint infection with an acute presentation using deep RNA sequencing and nuclear magnetic resonance spectroscopy, respectively. (biomedcentral.com)
Regulation1
Expression2
  • The relative mRNA expression amounts within the usual oral tissues and key OSCCs ranged from 6. (tcr-signal.com)
  • So, 13 representative tumors from your seven remaining handle animals had been analyzed for mRNA expression. (tcr-signal.com)
Factors1
  • Brassinosteroids (BRs) play an essential role in plant growth, and BRI1-EMS suppressor 1 (BES1)/brassinazole-resistant 1 (BZR1) family transcription factors integrate a variety of plant signaling pathways. (pubchase.com)
Template1
Domains1
  • In its absence, mtLSU particles (visualized by cryo-EM at the resolution of 2.6 Å) present disordered RNA domains, partial occupancy of bL36m and bound MALSU1:L0R8F8:mtACP anti-association module, allowing five mtLSU biogenesis intermediates with different intersubunit interface configurations to be placed along the assembly pathway. (nature.com)
Cell lines1
  • CDCA3 mRNA was signifi cantly up regulated in all OSCC derived cell lines compared together with the HNOKs. (tcr-signal.com)
Cancer1
  • Increased survivin mRNA transcripts were observed in 17-AAG and geldanamycin-treated HT-29 and HONE-1 cancer cells. (biomedcentral.com)