Moving genes. Medical search. Frequent questions

Britain's medicines regulator has authorized the world's first gene therapy treatment for sickle cell disease, in a move that could offer relief to thousands of people with the crippling disease in the U.K. In a statement on Thursday, Nov. 16, 2023, the Medicines and Healthcare Regulatory Agency said it approved Casgevy, the first medicine licensed using the gene editing tool CRISPR, which won its makers a Nobel prize in 2020. (wjbf.com)
It is with profound sadness I share that Gene took his life on June 15, 2023," Julie wrote. (ajc.com)

Then they used a powerful new gene editing technique, Crispr, to slip this sequence into the genome of a common gut bacteria, E. coli. (longnow.org)
In a statement Thursday, the Medicines and Healthcare Regulatory Agency said it approved Casgevy, the first medicine licensed using the gene editing tool CRISPR, which won its makers a Nobel prize in 2020. (wjbf.com)
The future of life-changing cures resides in CRISPR based (gene-editing) technology," said Dr. Helen O'Neill of University College London. (wjbf.com)
He had created the first gene-edited babies, he told the crowd - twin girls born from embryos he had modified using the gene-editing technique CRISPR. (marfapublicradio.org)
Jennifer Doudna, the Berkeley biochemist who codiscovered the CRISPR-Cas9 gene-editing technology, told Vision in 2016: "We are not going to do anything overnight. (vision.org)

DRB2 has been remarkably conserved throughout plant evolution, raising the possibility that translational repression is the ancient form of miRNA-directed gene regulation in plants, and that Dicer partnering proteins, such as human TRBP, might play a similar role in other eukaryotic systems. (nature.com)
They found that the genes encoding secreted proteins that evolved before the evolution of mollusks are being continually "co-opted" into the mantle gene regulatory network through the evolution of mollusks. (thefishsite.com)
Many proteins, and the genes that make them, aren't well understood, and there's still much to learn from the human genetic instruction book. (sciencenews.org)
To get anything done, a cell needs to read its genes, follow their instructions, and make proteins. (thetech.org)
Some people have versions of these melanin-making genes that make proteins that make a lot of pigment. (thetech.org)
First, we'll review how genes code for proteins. (thetech.org)
Genes need to be translated into proteins to do their job. (thetech.org)

One big remaining challenge and ethical question is whether scientists should ever again try to make gene-edited babies by modifying the DNA in human sperm, eggs or embryos. (marfapublicradio.org)
There are more than 10,000 single genetic mutations that collectively affect probably hundreds of million of people around the world," says Shoukhrat Mitalipov , a biologist at the Oregon Health and Science University in Portland who's been trying to find ways to safely gene-edit human embryos. (marfapublicradio.org)
Embryologists of the 1950s and '60s began to learn these things through the study of animals, but by the end of the 1960s, British physiologist Robert Edwards had moved on to creating in vitro human embryos. (vision.org)

Both sickle cell disease and thalassemia are caused by mistakes in the genes that carry hemoglobin, the protein in red blood cells that carry oxygen. (wjbf.com)
But under the guidance and expertise of Dr Colin Dinney at MD Anderson - who is really the person to be credited with the development of nadofaragene, which has been a passion and a brainchild of his - we looked at changing from developing the protein as the treatment of choice to developing a gene vector. (medscape.com)
The MESP2 gene provides instructions for making a transcription factor, which is a protein that attaches (binds) to specific regions of DNA and helps control the activity of particular genes. (medlineplus.gov)
The MESP2 protein controls the activity of genes in the Notch pathway, an important pathway in embryonic development. (medlineplus.gov)
The MESP2 protein regulates Notch activity by turning on (activating) genes in the Notch pathway, which ultimately block (repress) the activity of the NOTCH1 protein. (medlineplus.gov)
Mutations in the MESP2 gene prevent the production of any protein or lead to the production of an abnormally short, nonfunctional protein. (medlineplus.gov)
Use green fluorescent protein to tag expression of genes. (cshl.edu)
Other people have genes that make only a little bit of melanin making protein. (thetech.org)
There are only 4 letters: A, T, C, and G. The order of these letters in a gene determines which protein gets made. (thetech.org)
These differences in a gene can sometimes affect how a protein works by changing the amino acids in the protein. (thetech.org)
Sometimes a pigment gene doesn't make enough protein so little or no melanin gets made. (thetech.org)
GGS are known to be commensals and dase, M protein, streptolysin S, and certain exotoxin genes pathogens in domestic animals. (cdc.gov)
The ABCC2 gene provides instructions for making a protein that transports certain substances out of cells so they can be released (excreted) from the body. (medlineplus.gov)
ABCC2 gene mutations result in the production of a protein with reduced or absent activity that cannot effectively transport substances out of cells. (medlineplus.gov)
The black liver in affected individuals is due to a buildup of different substance normally transported out of the liver by the protein produced from the ABCC2 gene. (medlineplus.gov)
In addition, outliers in genes were found to be (i) enriched for biomineralization and ion homeostasis functions related to low pH response, (ii) less central to the protein-protein interaction network, and (iii) underrepresented among genes highly expressed during early development. (bvsalud.org)

Sio Gene Therapies (NASDAQ:SIOX) reported its Q3 earnings results on Friday, February 11, 2022 at 07:00 AM. Here's what investors need to know about the announcement. (investorplace.com)
This agent, which was approved by the FDA on December 16, 2022, is the first gene therapy indicated for non-muscle-invasive disease. (medscape.com)

Now, researchers at CSHL have shown that RNAi can be used to set the level of gene activity in stem cells on "low," "medium," or "high. (sciencedaily.com)
The new study indicates that stable suppression of deleterious genes by RNAi--in which adult stem cells are isolated, modified ex vivo, and then re-introduced into the affected individual--might be an effective strategy for treating human disease. (sciencedaily.com)
The study illustrates the ease with which RNAi "gene knockdowns" can be used to create a full range of mild to severe phenotypes (something that geneticists dream about), as well as the potential of RNAi in developing stem cell-based and other therapeutic strategies. (sciencedaily.com)
Along with a recent study by Hannon and his colleagues that demonstrated germline transmission of RNAi, the current study establishes RNAi as a convenient alternative to traditional, laborious, and less flexible homologous recombination-based gene knockout strategies for studying the effects of reduced gene expression in a wide variety of settings. (sciencedaily.com)
Surprisingly, most of these discarded genes play a part in RNA interference or RNAi, a process that preserves the integrity of the genome in fungi and other organisms. (sciencedaily.com)
Surprisingly, most of these discarded genes play a part in RNA interference or RNAi, a defense mechanism employed by fungi and other organisms to protect the integrity of their genomes. (sciencedaily.com)
Five years ago, researchers in the Heitman lab participated in an international collaborative consortium to sequence the genome of this outbreak species and discovered that it had lost two genes involved in RNAi, a process previously thought to be key to its survival. (sciencedaily.com)
The RNAi gene-silencing machinery normally shreds the genetic instructions for harmful viruses or silences rogue genes that might contaminate the fungus' genome. (sciencedaily.com)
But Cryptococcus deuterogatti had holes in its genome where the two RNAi genes should have been. (sciencedaily.com)
Armed with this information, Billmyre hypothesized that other genes in this missing set of genes might also function in RNAi. (sciencedaily.com)
The researchers then conducted a number of genetic and molecular analyses to determine if any of these lost genes played a role in RNAi. (sciencedaily.com)
They mutated each of the genes in Cryptococcus neoformans , which has fully functioning RNAi machinery, to see if these genes were needed for the fungi to silence extra genetic material. (sciencedaily.com)
Joseph Heitman, the James B. Duke professor and chair of Molecular Genetics and Microbiology, said he expected to find maybe one or two other genes involved in RNAi. (sciencedaily.com)
We could have imagined that the species lost a couple of RNAi genes, and then a smattering of genes involved in all other kinds of processes," said Heitman. (sciencedaily.com)

Roddenberry, who has overseen the production of "Gene Roddenberry's Earth: Final Conflict," "Gene Roddenberry's Andromeda" and, most notably, the "Star Trek" brand, talks about the "Trek" reboot, his new comic book … and saving the ocean. (thewrap.com)
No shade towards Gene Roddenberry's Andromeda or anything of his other original works. (nerdist.com)

Gene editing has the potential to provide a cure for millions of patients living with genetic disease," said Brian C. Thomas, chief executive officer and co-founder of Metagenomi. (biospace.com)
Our partnership with Moderna is designed to accelerate the creation of genetic medicines using Metagenomi's naturally derived, compact, modular and precise gene editing systems. (biospace.com)
Packaging random snippets of DNA into virus-like capsules known as gene transfer agents, or GTAs, may be a key way for marine bacteria to exchange genetic information, a new paper in Science suggests. (biofortified.org)
Patients first receive a course of chemotherapy, before doctors take stem cells from the patient's bone marrow and use genetic editing techniques in a laboratory to fix the gene. (wjbf.com)
A peek at tardigrades' genetic diaries may dispel a rumor about an amazing feat the tiny creatures were supposed to perform: borrowing large numbers of genes from other organisms. (sciencenews.org)
Gene editing is subject to the same rules as genetic modification in the EU but differs in that it does not result in the introduction of DNA from other species. (yahoo.com)
Because of the universality of the genetic code, the polymerases of one organism can accurately transcribe a gene from another organism. (cshl.edu)
Recombinant DNA technology â€" genetic engineering â€" has made it possible to gain insight into how genes work. (cshl.edu)
This method uses homologous recombination to disable a gene of interest to produce a genetic knockout. (cshl.edu)
The " it's gotta be genetic " mindset will still live on in the largely autism ignorant, advertising revenue dependent, major mainstream media institutions in LA, New York and Toronto but in the informed autism world it is being replaced by the gene environment autism research paradigm. (blogspot.com)
The situation is more complex when it comes to patents that in some way claim genes isolated, extracted or derived from viruses and related genetic information, or that claim potentially new uses or applications of genes or genetic information. (who.int)
In some countries laws specifically provide that isolated genetic material, such as gene sequences, may be considered patentable inventions (as long as they meet the other criteria for the granting of a patent) even if corresponding genes occur in nature. (who.int)
This situation typically arises when it is considered that the isolated gene or genetic material may serve a distinct useful purpose. (who.int)
Telomeres are used to move the cell's genetic material in preparation for cell division. (msdmanuals.com)
Diagnosis is confirmed by identifying a molecular genetic mutation in the HPRT gene. (medscape.com)

While this gene-swapping mechanism has been known for decades, the extent to which GTAs were relevant to microbes in the real world was unclear, having been observed in a limited number of species and almost exclusively inside microbiology labs. (biofortified.org)
In evolution, genes often move between different species. (biofortified.org)
The authors conclude that across distant and closely related species, both co-option of existing genes and the rapid evolution of novel genes have been recurring themes in the diversification of mollusk mantle transcriptomes. (thefishsite.com)
Concept 34: Genes can be moved between species. (cshl.edu)
For example, different species of bacteria obtain antibiotic resistance genes by exchanging small chromosomes called plasmids. (cshl.edu)
In the early 1970s, researchers in California used this type of gene exchange to move a "recombinant" DNA molecule between two different species. (cshl.edu)
Researchers found that the pathogen shed over a dozen different genes as it evolved into a new, more virulent species. (sciencedaily.com)
Now, researchers have found that the pathogen tossed aside over a dozen different genes on its way to becoming a new, more virulent species. (sciencedaily.com)
They found that C. deuterogatti has lost 14 genes compared to the other, less pathogenic, species. (sciencedaily.com)
genomes may elucidate genes that are unique to those species of spirochetes associated with ticks. (cdc.gov)

At least three mutations in the MESP2 gene have been found to cause spondylothoracic dysostosis, a condition characterized by abnormal development of bones in the spine and ribs. (medlineplus.gov)
Similarly, the phenotypes of gene mutations and the efficacy of drugs and other agents can be tested using recombinant systems. (cshl.edu)
These mutations particularly affect moving bilirubin into bile. (medlineplus.gov)
which means both copies of the gene in each cell have mutations. (medlineplus.gov)
Devgun MS, El-Nujumi AM, O'Dowd GJ, Barbu V, Poupon R. Novel mutations in the Dubin-Johnson syndrome gene ABCC2/MRP2 and associated biochemical changes. (medlineplus.gov)
Lesch-Nyhan disease and its variants are caused by mutations in the HPRT gene on the X chromosome. (medscape.com)

Mike Wigler shows how all organisms share similar genes, called homologs. (cshl.edu)
All organisms that reproduce sexually-that is, where two parents contribute genes to create a new individual-must bring egg and sperm together. (vision.org)

Similar evolutionary reasoning may explain why many people in malaria-prone parts of Africa carry gene variants linked to malaria resistance. (gnxp.com)
As it secretes the shell, each mollusk mantle uses a mixture of ancient evolved genes (long before the major mollusk evolutionary radiation 500 million years ago) and more recently evolved genes. (thefishsite.com)
Once one gene in a pathway is lost, the researchers hypothesize that an organism can find itself on a slippery evolutionary slope as other genes that are no longer of benefit are lost in quick succession. (sciencedaily.com)
David Epstein on the genes that make us move-and their evolutionary purpose. (thedailybeast.com)

Recombinant DNA technology has made it possible to test gene function in bacteria or cell cultures rather than animal models. (cshl.edu)
In cases where it is impractical to test gene function using animal models, genes can first be expressed in bacteria or cell cultures. (cshl.edu)
and I'm going to specifically talk about the genes that are responsible for producing a mechanism bacteria will use to become resistant to antimicrobial agents. (cdc.gov)
They basically capture these antimicrobial resistance genes and then they move them within the bacteria or between bacteria. (cdc.gov)
This is where plasmids play a big role in moving these genes around bacteria--different bacteria. (cdc.gov)
it's like a highway where bacteria sort of live and breathe and then these genes move between them the whole time. (cdc.gov)
So, they hold onto these genes but they also have the ability to spread them to other bacteria. (cdc.gov)

Interestingly, the 7R variant of the DRD4 gene is more common in populations that have migrated long distances, as well as those that are nomadic, compared with settled populations. (thedailybeast.com)
Now, interestingly enough is these genes (these antimicrobial resistant genes), they can find their way onto certain clones. (cdc.gov)

These patients are identified by demonstrating HPRT deficiency or a mutation in the HPRT gene. (medscape.com)
The HPRT gene has 9 exons, with the coding region depicted as light gray boxes. (medscape.com)

Gene Expression: Bruce Lahn moving on to non-IQ projects? (gnxp.com)
In the present study, we developed a high-content pipeline, the large-area spatial transcriptomic (LaST) map, which can quantify single-cell gene expression in situ. (cdkl5.com)
In the largest study ever performed, the authors generated a transcriptome (the complete gene expression network) from 11 different bivalves and gastropods. (thefishsite.com)
One of the most influential regions appeared to be regulating the expression of a gene called EVI1, which is known for its role in embryonic limb development. (fudan.edu.cn)

Cambridge, Mass.-based Moderna and Emeryville, Calif.-based Metagenomi inked a strategic research and development deal on new gene editing systems for in vivo (in the body) human therapies. (biospace.com)
Their discovery platform and expertise will expand Moderna Genomics' ongoing efforts to develop innovative in vivo gene editing therapies to address a significant unmet medical need. (biospace.com)
The board of microcap Sio Gene Therapies (SIOX) has decided to dissolve the company and liquidate its assets following a review of potential strategic alternatives. (investorplace.com)
Gene therapies have been tested for other solid tumors for quite some time - for decades. (medscape.com)
However in the last years, immunotherapies using immune-checkpoint inhibitors (ICI), as well as cellular therapies, have moved into the limelight as promising alternative treatments. (nature.com)

Work in the Rowitch laboratory investigates the precise way that the CDKL5 gene is expressed in neurons of the brain. (cdkl5.com)
In recent years, scientists have produced new evidence about the risks and possible shortcomings of gene-editing , while also developing more sophisticated techniques that could be safer and more precise. (marfapublicradio.org)
Besides modification based on a second-generation CAR, more advanced CAR-immune cell therapeutics are being tested, which utilize precise insertion of genes to circumvent graft-versus-host disease (GvHD) or employ a dual targeting approach and adapter CARs in order to avoid therapy resistance caused by antigen loss. (nature.com)

The use of the word 'cure' in relation to sickle cell disease or thalassemia has, up until now, been incompatible," she said in a statement, calling the MHRA's approval of gene therapy "a positive moment in history. (wjbf.com)

ORLANDO -- Interferon-based gene therapy led to 12-month recurrence-free survival in more than a third of patients with heavily pretreated nonmuscle-invasive bladder cancer (NMIBC), according to a study reported here. (medpagetoday.com)
Intravesical gene therapy might achieve sustained high levels of IFNα by inducing endogenous production by host cells. (medpagetoday.com)
This will help us plan for future gene therapy. (cdkl5.com)
Professor Rowitch leads the Department of Pediatrics at Cambridge University, where there are plans to build new facilities for delivery of gene therapy safely into the brain of children that can support eventual clinical trials for CDKL5 gene therapy. (cdkl5.com)
LONDON (AP) - Britain's medicines regulator has authorized the world's first gene therapy treatment for sickle cell disease, in a move that could offer relief to thousands of people with the crippling disease in the U.K. (wjbf.com)
the agency is expected to make a decision early next month, before considering another sickle cell gene therapy. (wjbf.com)
What do you think made this gene therapy successful? (medscape.com)
The incremental difference of this gene therapy over others is it's locally delivered - it's easily delivered by putting a catheter into the bladder, putting the medicine inside the bladder, and then allowing the gene to transfuse into the bladder cells. (medscape.com)
Most CAR-T cell-based gene therapy products that are under clinical evaluation consist of autologous enriched T cells, whereas CAR-NK cell-based approaches can be generated from allogeneic donors. (nature.com)

U-Haul moving boxes are specifically designed to make packing and loading easier. (uhaul.com)
Whether its boxes, packing tape, bubble cushion wrap or any other type of packing supplies, U-Haul wants to make moving that much easier for you. (uhaul.com)
The new medicine, Casgevy, works by targeting the problematic gene in a patient's bone marrow stem cells so that the body can make properly functioning hemoglobin. (wjbf.com)
By the early 1980s, other scientists adapted the technique and spliced a human gene into E. coli to make recombinant human insulin and growth hormone. (cshl.edu)
Today we have hands-on access to the very genes that make us who we are, opening the window to a whole new era of reproductive interventions. (vision.org)
To really understand how genes make melanin, we're going to have to go over a few topics. (thetech.org)

Multiple studies-including a meta-analysis of all published studies-have also replicated the finding that one of those variants, the 7R version of the DRD4 gene, increases an individual's risk for attention deficit hyperactivity disorder, or ADHD. (thedailybeast.com)

A foreword by Gene Luen Yang and scholarly introductions and apparatus by Ben Saunders offer further insight into the enduring significance of Captain America and classic Marvel comics. (marvel.com)

The last time the world's scientists gathered to debate the pros and cons of gene-editing - in Hong Kong in late 2018 - He Jiankui, a biophysicist and researcher at Southern University of Science and Technology in Shenzhen, China, shocked his audience with a bombshell announcement . (marfapublicradio.org)

The study, published in the February issue of Nature Genetics, focussed on the role of a tumor suppressor gene called p53 in a mouse model of lymphoma. (sciencedaily.com)

It has a proprietary discovery engine that starts with vast amounts of metagenomic data "to unlock 4 billion years of microbial evolution and identify new types of gene editing systems. (biospace.com)

To his surprise, they found that 11 of the 14 missing genes they surveyed were involved in gene silencing. (sciencedaily.com)
In the most comprehensive analysis to date, researchers found that the shapes of fingerprints-whether they are circular, wavy, or winding-are influenced by the genes responsible for limb development instead of skin patterning. (fudan.edu.cn)
Despite no evidence of global population structure, we found a suite of single-nucleotide polymorphisms (SNPs) tightly correlated with local pH variability (outlier SNPs), which were overrepresented in regions putatively involved in gene regulation (long noncoding RNA and enhancers), supporting the idea that variation in regulatory regions is important for local adaptation to variability. (bvsalud.org)

LONDON (Reuters) - Britain's farming and environment minister George Eustice said on Thursday that government legislation to ease the regulatory regime for gene editing after breaking away from EU rules would initially focus on crops, not farm animals. (yahoo.com)

Screening 46 candidate genes for astrocyte diversity across the mouse cortex, we identified superficial, mid and deep astrocyte identities in gradient layer patterns that were distinct from those of neurons. (cdkl5.com)

have begun to peel back the complex gene networks that control the secretions from the outer layer of cells on the mantle. (thefishsite.com)
Several lines of scientific evidence have begun to implicate genes that control dopamine. (thedailybeast.com)

In 1997 Gene launched ScienceMaster.com, an online science education portal where he brought together his love of writing with his interest in the sciences. (scienceiq.com)

As scientific tools for probing genes become increasingly powerful, research into human differences has exploded. (gnxp.com)

In the more than four years since He's stunning announcement, scientists have continued to hone their gene-editing powers. (marfapublicradio.org)
The scientists, led by Greg Hannon and his CSHL colleague, Scott Lowe, knew that completely deleting the p53 gene causes lymphomas to develop much sooner, and in a more aggressive, highly-invasive form, than lymphomas that develop when the p53 gene is present. (sciencedaily.com)
The study, presented January 6 in the journal Cell , could help scientists better understand the association between genes and phenotypical traits in humans. (fudan.edu.cn)
A set of scientists have proposed the controversial idea that hyperactivity and impulsivity may have had advantages in the ancestral state of man in nature, leading to the preservation of genes that increase ADHD risk. (thedailybeast.com)

He personally believes it is possible that some populations will have more advantageous intelligence genes than others. (gnxp.com)

Tim Lightfoot, director of the Sydney and J.L. Huffines Institute for Sports Medicine and Human Performance at Texas A&M has authored papers on voluntary physical activity in rodents and humans, and he sees a connection between ADHD, exercise, and dopamine genes. (thedailybeast.com)

But later it turns out fingerprint pattern is associated with genes for limb growth, which are critical for fetal development. (fudan.edu.cn)
For example, people with whorl-shaped fingerprints on both of their little fingers tend to have longer little fingers than those who do not, and this correlation is strongly linked to genes involved in limb development. (fudan.edu.cn)
Our study suggests that dermatoglyphic patterns are affected by crucial development genes, which provides a strong theoretical basis for this kind of pleiotropy. (fudan.edu.cn)

The genes of cells program a process that, when triggered, results in death of the cell. (msdmanuals.com)

It seemed possible that these genes are regulated by transcription factors that are themselves regulated by miRNAs, and at a translational level by a process involving DRB2. (nature.com)

The parents of an individual with an autosomal recessive condition each carry one copy of the mutated gene, but they typically do not show signs and symptoms of the condition. (medlineplus.gov)

Most affected individuals have the Glu103Ter mutation in both copies of the MESP2 gene. (medlineplus.gov)
However, a few people with spondylothoracic dysostosis have the Glu103Ter mutation in one copy of the MESP2 gene and either the Leu125Val or the Glu230Ter mutation in the other copy. (medlineplus.gov)

We find that CDKL5 genes are turned on and off in a dynamic manner as the mouse brain develops. (cdkl5.com)

The Victor archives show an October 9, 1929, entry stating that the vocal duet of Jimmie Long and Gene Autry with two Hawaiian guitars, directed by L. L. Watson, recorded "My Dreaming of You" (Matrix 56761) and "My Alabama Home" (Matrix 56762). (wikipedia.org)
Machida I, Wakusawa S, Sanae F, Hayashi H, Kusakabe A, Ninomiya H, Yano M, Yoshioka K. Mutational analysis of the MRP2 gene and long-term follow-up of Dubin-Johnson syndrome in Japan. (medlineplus.gov)

Eric Huang, general manager and chief scientific officer of Moderna Genomics, said, "Metagenomi has demonstrated the power of its proprietary metagenomics approach that mines the Earth's natural environment to discover next-generation gene editing tools and has developed discovery capabilities with the potential to address multiple disease. (biospace.com)
Whatever the reason, the discovery could pave the way for future studies using comparative genomics to identify other sets of related genes. (sciencedaily.com)
Moving from simple observation and dissection to microscopy and genomics, the curious have opened new windows to understanding. (vision.org)

His wife, Julie Gates, posted the sad news on the public Gene & Julie Facebook page. (ajc.com)

The largest metagenomic view of the developing world uncovers "mobile genes" that reveal how culture shapes the human microbiome. (broadinstitute.org)
Today, as we combine IVF procedures with an expanding knowledge of not only the human genome but also gene-editing tools, new and previously unimaginable options have opened: before an IVF embryo is implanted in a womb, we can now alter it genetically. (vision.org)
The gene encoding the human enzyme was cloned and sequenced by Friedmann and colleagues in 1985. (medscape.com)

From the game-changing twin study to the emerging clues on environmental risk factors, these studies highlight the important role of gene-environmental interactions in autism. (blogspot.com)

Subsequently, cells are transduced with CAR-encoding genes using (mostly) viral vectors. (nature.com)

Genotype-Phenotype Correlations in Lesch-Nyhan Disease: Moving Beyond the Gene. (medscape.com)

Then we can talk about how when some specific genes don't work quite right, people can end up with blue eyes. (thetech.org)

Rod Roddenberry, the son of "Star Trek" creator Gene Roddenberry, is embarking on a new mission at this year's Comic-Con. (thewrap.com)
But it's exactly what writer/producer Gene Roddenberry envisioned when he created Star Trek in 1964. (nerdist.com)
Gene Roddenberry, born August 19, 1921, changed everything in nerd culture with Star Trek . (nerdist.com)

a large study providing further confirmation that autism causation results from gene environment interaction. (blogspot.com)

A major anchor shakeup is underway at WJAR, according to GoLocalProv: An announcement has just been made to the staff that main anchor Gene Valicenti is being moved off the 11pm newscast. (adweek.com)
Confirmation of the diagnosis is most reliably made by identification of the HPRT1 gene. (medscape.com)

Particular versions of dopamine receptor genes have been associated with higher physical activity and lower body mass index. (thedailybeast.com)

BRISTOL, Va. (WJHL) - The Friday night lights at Gene Malcolm Stadium won't be as bright on the south end of the Virginia High School Bearcats homestand for their football season opener. (wjhl.com)

16833. Concept 40: Living things share common genes. (cshl.edu)
16834. Animation 40: Living things share common genes. (cshl.edu)

20232

CRISPR5

Proteins7

Embryos3

Protein16

20222

RNAi14

Roddenberry's Andromeda2

Genetic15

Species10

Mutations6

Organisms2

Evolutionary4

Bacteria7

Interestingly2

HPRT2

Expression4

Therapies5

Precise3

Thalassemia1

Therapy9

Make6

Variants1

Captain America1

World's1

Genetics1

Evolution1

Found3

Regulatory1

Diversity1

Begun2

Sciences1

Differences1

Scientists4

Populations1

Humans1

Development3

Cell1

Transcription1

Typically1

Mutation2

Find1

Long2

Genomics3

News1

Human3

Role1

Cells1

Disease1

Work1

Star Trek3

Study1

Made2

Activity1

High1

Share2