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  • mucosa
  • The clinician will place a fiber-optic probe designed to measure the polarized reflectance spectra over the visible optical region on a site of interest in the subject's mouth, including lesional mucosa, normal adjacent and contralateral mucosa. (clinicaltrials.gov)
  • The probe is placed gently against the mucosa, and different colors of light are directed through the probe to a small area (the lesion and the normal-appearing area) of mouth tissue. (knowcancer.com)
  • oral
  • The goal of this clinical research study is to evaluate fluorescence imaging, widefield fluorescence imaging, point spectroscopy imaging methods, and or/ oral brush cytology that may help doctors monitor patients at an increased risk of developing an oral cancer, including those with pre-cancerous lesions in the mouth. (clinicaltrials.gov)
  • The goal of this clinical research study is to learn how Actos (pioglitazone) may affect oral premalignant lesions (OPLs) and/or the risk of mouth cancer. (clinicaltrials.gov)
  • Oral cancer can form in any part of the mouth. (icdlist.com)
  • Most oral cancers begin in the flat cells that cover the surfaces of your mouth, tongue, and lips. (icdlist.com)
  • Scientists need to better understand whether fluorescence from the oral cavity (mouth) can be used to tell which cells are abnormal. (knowcancer.com)
  • Microscope
  • Fluorescent imaging use instruments that shine different wavelengths (colors) of light in the mouth taking fluorescence pictures through a portable head light or by taking fluorescent and reflectance pictures through a dental microscope using a digital camera. (clinicaltrials.gov)
  • Checking mouth tissue samples under a microscope may also help detect abnormal cells. (clinicaltrials.gov)
  • A special light source has been attached to this microscope to provide different colors of light that can shine in the mouth. (knowcancer.com)
  • This microscope also has a digital camera attached to it so that researchers can take pictures of fluorescence and reflectance in the mouth in order to record what is seen with the different light colors. (knowcancer.com)
  • fluorescence
  • PS2 imaging system that shines different wavelengths (colors) of light in the mouth and can collect and analyze fluorescence and reflected light. (clinicaltrials.gov)
  • Researchers want to better understand if fluorescence and reflectance from mouth tissue can be used to tell which cells are abnormal. (knowcancer.com)
  • reflectance
  • In this study the investigators are conducting research to determine whether a new optical device using polarization reflectance spectroscopy can help doctors or dentists identify abnormalities in the mouth that require follow-up. (clinicaltrials.gov)
  • cancers
  • This information may help doctors detect early mouth cancers and treat all areas affected by cancerous changes. (knowcancer.com)
  • site
  • For multiple neoplasms of the same site that are not contiguous, such as tumors in different quadrants of the same breast, codes for each site should be assigned. (icd10data.com)
  • colors of light
  • Fast EEM4 - Different colors of light are directed through fibers to the lining of the mouth and then light is collected and sent to a special camera and a computer to be analyzed. (clinicaltrials.gov)
  • once
  • If you are eligible to take part in this study, you will take gefitinib treatment by mouth once a day, every day, at about the same time in the morning. (clinicaltrials.gov)
  • 250 mg by mouth once a day, every day, at about same time in morning. (clinicaltrials.gov)
  • White
  • If one of these systems are used, the clinician will examine the inside of your mouth with a gloved finger while using standard white light or one or more of the imaging systems for viewing. (knowcancer.com)