• The Drosophila mutants dunce1, rutabaga2080, and radish1 share olfactory memory defects but differ conspicuously for short-term processes relevant to visual attention. (the-mouse-trap.com)
  • We characterized an olfactory-processing pathway, comprised of inhibitory projection neurons (iPNs) that target the LH exclusively, at morphological, functional and behavioral levels. (elifesciences.org)
  • We recorded reduced synaptic inhibitory feedback on mitral/tufted (M/T) cells, in the OB slices from ELS mice, explaining the learning deficiency caused by compromised refinement of OB output. (nature.com)
  • The objective of this study was to analyze the ability of two drugs that improve cognition in different experimental models, the acetylcholinesterase inhibitor donepezil and the non-competitive GABA(A) antagonist pentylenetetrazole (PTZ), to improve the cognitive deficits found in TS mice. (flt-3inhibitors.com)
  • They weer aqble to show that despite overt similar olfactory memory deficits, the attention-like processes worked in opposite ways in the two mutant models. (the-mouse-trap.com)
  • Although it is known that olfactory centres are entwined with limbic brain regions, olfactory dysfunctions under conditions of ELA remain elusive. (nature.com)
  • Perception of these chemical signals may be olfactory or by contact. (lookformedical.com)
  • The role of SOM-INs was revealed by learning-dependent refinement of Ca 2+ dynamics quantified by GCaMP6f signals, which was absent in ELS mice. (nature.com)
  • Sensorimotor abilities, including vision, hearing, strength and motor coordination, as well as locomotor activity in the home cage, were not modified by any chronic treatment in TS and CO mice. (flt-3inhibitors.com)
  • We illustrate how animals integrate these learning principles using the fruit fly olfactory learning circuit, one of nature's best-characterized and highly optimized schemes for learning. (jneurosci.org)
  • Compromised mammillary body connectivity and psychotic symptoms in mice with di- and mesencephalic ablation of ST8SIA2. (mhh.de)
  • Other insects, such as honey bees and hawk moths, have olfactory systems with a similar architecture and might also employ a similar spatial approach to encode information regarding the intensity and identity of odors. (elifesciences.org)
  • They are found in tropical and subtropical waters and characterized by short spines along the length of the tail and body. (lookformedical.com)
  • Utilizing the mdx mouse product, we initiated studies about the effect of increasing S1P degrees in dystrophic mice, and found that short term therapy with THI improves muscle strength and function following acute injury with cardiotoxin. (hsp70inhibitor.com)
  • This mouse shares many phenotypic characteristics with people with Down syndrome including behavioral and cognitive alterations. (flt-3inhibitors.com)
  • Rescue of synaptic and cognitive functions in polysialic acid-deficient mice and dementia models by short polysialic acid fragments. (mhh.de)
  • By implementing go/no-go odour discrimination paradigm, we observed olfactory learning and memory impairments in early life stressed (ELS) male mice. (nature.com)
  • The drugs were administered p.o. to TS and CO mice for 8 weeks and a behavioral characterization was performed. (flt-3inhibitors.com)
  • Lowered c-Fos activity in the external plexiform layer and a reduction in the number of dendritic processes of somatostatin-releasing, GABAergic interneurons (SOM-INs) in the ELS mice led us to hypothesise the underlying circuit. (nature.com)
  • by If you represent on a desirable download, like at test, you can seem an value mouse on your submission to do eligible it is infinitesimally detached with perivitelline. (need4speed.com)
  • We provide evidence for a feature-based map in the LH, and elucidate its role as the center for integrating behaviorally relevant olfactory information. (elifesciences.org)
  • Conversely, photo-inhibition caused learning deficiency in control animals, while it completely abolished the learning in ELS mice, confirming the adverse effects mediated by SOM-INs. (nature.com)
  • The most commonly used model of Down syndrome, the Ts65Dn (TS) mouse, is trisomic Bucladesine in vivo for most of the region of MMU16 that is homologous to HSA21. (flt-3inhibitors.com)
  • Superimposed on that, in a whole assortment of colors, is a confocal microscope image of the 'mushroom bodies,' brain areas that process sensory stimuli and form memories. (nih.gov)
  • Oxytocin is released in target areas such as lateral septum, hippocampal CA2, and auditory cortex, to affect responses to social stimuli and thus change behavior in C57Bl/6 mice. (nih.gov)
  • Here, we present an analysis of a brain proteomic dataset that indicates that multiple planar cell polarity proteins are affected by Nab2 loss, and couple this with genetic data that demonstrate that Nab2 has a previously unappreciated role in restricting the growth and branching of dendrites that elaborate from larval body-wall sensory neurons. (bvsalud.org)
  • Further analysis confirms that Nab2 loss sensitizes sensory dendrites to the genetic dose of planar cell polarity components and that Nab2-planar cell polarity genetic interactions are also observed during Nab2-dependent control of axon projection in the central nervous system mushroom bodies. (bvsalud.org)
  • Particularly exciting areas include high-throughput screening, single-molecule spectroscopy and whole-body in vivo imaging. (nature.com)
  • In vivo evaluation of the bystander effect in mouse models demonstrated that for effective therapy, at least 1% of tumor cells need to be delivered with TK-NTR-encoding MCs. (regenerativemedicine.net)
  • The pinpricks of light in this starry night sky are actually green fluorescent protein, marking specific cells in a mouse retina. (nih.gov)
  • Random mixing of fluorescent dyes created this psychedelic slice of a mouse brain. (nih.gov)
  • Overall, the image shows the locations, enormous size, and complex branching patterns of neurons that process olfactory information. (nih.gov)
  • The North American beaver lives in forests (near water bodies) in the northern parts of North America, with a lifespan between 10 to 15 years. (northamericannature.com)
  • Cats can hear sounds too faint or too high in frequency for human ears, such as those made by mice and other small game. (docshare.tips)