LysineFibroblastsEmbryo, MammalianCells, CulturedMice, KnockoutAmino Acid SequenceMolecular Sequence DataCell LineProtein BindingBinding SitesMutationSignal TransductionAcetylationMutagenesis, Site-DirectedFibroblast Growth Factor 2Base SequenceProtein Structure, TertiaryPhosphorylationModels, MolecularNIH 3T3 CellsKineticsGene Expression RegulationHistonesDNA-Binding ProteinsApoptosisTransfectionTumor Suppressor Protein p53Recombinant ProteinsCell ProliferationMethylationNuclear ProteinsTranscription FactorsCell AgingFeeder CellsProtein Processing, Post-TranslationalProtein ConformationRNA, MessengerFibroblast Growth FactorsSequence Homology, Amino AcidEmbryonic Stem CellsUbiquitinationBlotting, WesternCell Transformation, NeoplasticAmino Acid SubstitutionGene Knockout TechniquesAmino AcidsDNA DamageTranscription, GeneticMice, Inbred C57BLStructure-Activity RelationshipCell DifferentiationHeLa CellsProteinsEnzyme ActivationRNA, Small InterferingCarrier ProteinsCell SurvivalCell DivisionCell Line, TumorProtein-Serine-Threonine Kinases3T3 CellsCell Line, TransformedCell CycleSkinGene DeletionPeptidesDNACitraconic AnhydridesSubstrate SpecificityEmbryo LossInduced Pluripotent Stem CellsUbiquitinbcl-2 Homologous Antagonist-Killer ProteinCell NucleusPeptide FragmentsHEK293 CellsNuclear ReprogrammingRecombinant Fusion ProteinsMembrane ProteinsImmunoprecipitationTime FactorsProtein Structure, SecondaryModels, BiologicalCell Cycle ProteinsImmunoblottingEscherichia coliPromoter Regions, GeneticSequence AlignmentCell Culture TechniquesTumor Suppressor ProteinsUbiquitin-Protein LigasesGene ExpressionProtein TransportReverse Transcriptase Polymerase Chain ReactionReceptors, Fibroblast Growth FactorAdaptor Proteins, Signal TransducingPyridoxal PhosphateDNA RepairMice, Mutant StrainsMicroscopy, Fluorescence