FibroblastsEmbryo, MammalianMice, KnockoutCells, CulturedCell LineApoptosisSignal TransductionTransfectionBlotting, WesternPhosphorylationNIH 3T3 CellsFibroblast Growth Factor 2Cell Transformation, NeoplasticGene Expression RegulationCell AgingCell ProliferationFeeder CellsTumor Suppressor Protein p53RNA, MessengerCell Line, Transformed3T3 CellsFibroblast Growth FactorsCell DivisionCell SurvivalEmbryonic Stem CellsDNA-Binding ProteinsGene Knockout TechniquesSkinDNA DamageNuclear ProteinsCell DifferentiationCell CycleMice, Inbred C57BLMolecular Sequence DataTranscription FactorsMutationInduced Pluripotent Stem CellsRNA, Small InterferingBase SequenceNuclear ReprogrammingTranscription, GeneticProtein-Serine-Threonine KinasesProtein BindingEmbryo LossCell Culture Techniquesbcl-2 Homologous Antagonist-Killer ProteinCell Line, TumorEnzyme ActivationGene DeletionReverse Transcriptase Polymerase Chain ReactionMice, Mutant StrainsGene ExpressionCell MovementPromoter Regions, GeneticCell NucleusTime FactorsTumor Suppressor ProteinsGene TargetingReceptors, Fibroblast Growth FactorHeLa CellsDNA RepairMice, TransgenicCarrier ProteinsCell Cycle ProteinsDNAMicroscopy, FluorescenceImmunoblottingAdipogenesisBALB 3T3 CellsAdaptor Proteins, Signal TransducingCyclin-Dependent Kinase Inhibitor p21CollagenFibroblast Growth Factor 1Genomic InstabilityProto-Oncogene ProteinsIntracellular Signaling Peptides and ProteinsProteinsDown-RegulationUp-RegulationOctamer Transcription Factor-3Ultraviolet RaysCell AdhesionActinsCoculture TechniquesImmunoprecipitationAmino Acid SequenceNF-kappa BExtracellular MatrixModels, BiologicalPluripotent Stem CellsHEK293 CellsPhenotypeCulture Media, ConditionedI-kappa B KinaseRecombinant ProteinsMembrane ProteinsAutophagyMitochondriaCyclin-Dependent Kinase Inhibitor p16Transcriptional Activation