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  • brain
  • The model of handedness provides a case where one brain region (dominant motor cortex) is known to have a stronger BOLD response over another (non-dominant motor cortex) during hand motor task performance. (ox.ac.uk)
  • stimulus
  • These features are enhanced after treatment with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP), which causes a consistent PD-like motor impairment, while high-frequency (HF) DBS (i.e., ≥100 Hz) strongly reduces the short-term patterns (period: 3-7 ms) both before and after MPTP treatment, and elicits a short-latency post-stimulus activation. (frontiersin.org)
  • enhances
  • Overall, the selective suppression of non-stationary features and the increased modulation of the spike probability suggest that HF STN DBS enhances the neuronal activation in motor and sensory cortices, presumably because of reinforcement mechanisms, which perhaps involve the overlap between feedback antidromic and feed-forward orthodromic responses along the BG-thalamo-cortical loop. (frontiersin.org)
  • synaptic
  • These neural signals continue down the lateral corticospinal tract where they connect to the lower motor neurons via interneurons or direct synaptic connections. (wisegeek.com)
  • The excitability of the motor cortex as a whole is a function of single cell excitability, synaptic strength, and the balance between excitatory cells and inhibitory cells. (springer.com)
  • signals
  • This study suggests that, if hand motor signals are accessed by the oculomotor system, this is upstream of M1. (jneurosci.org)
  • A leading hypothesis is that the oculomotor system has access to hand motor signals. (jneurosci.org)
  • basal
  • Thus, analysis of the interaction of basal ganglia spiking with cortical broadband could yield great insight into basal ganglia-cortex dynamics in PD. (jneurosci.org)
  • Thus
  • Thus, we compared the reliability of both motor mapping approaches in a preclinical trial. (egms.de)
  • Thus, the motor cortex is adaptable, or plastic. (upmc.com)
  • The components of the TEP that are most relevant to motor SI will thus be identified. (clinicaltrials.gov)
  • We surmise that motor cortex may thus employ state-dependent computation to achieve very rapid changes between bistable motor states when the demand for speed exceeds the demand for accuracy. (frontiersin.org)
  • neuron
  • Whenever I see someone as brilliant as Stephen Hawking suffering from motor neuron disease, it makes me feel sad that such a great intellect has been paralyzed by a debilitating condition. (wisegeek.com)
  • area
  • Damage to this area can also interfere with the learning of motor skills . (wisegeek.com)
  • Is the Subject Area "Motor neurons" applicable to this article? (plos.org)
  • The electron microscope has been used to study the normal structure of the motor cortex (area 4 of Brodmann) and area 3b of the somatic sensory cortex in the monkey. (bl.uk)
  • The termination of the thalamo-cortical and commissural afferent fibres to both cortical areas, and the association connections to the motor cortex from the somatic sensory cortex and area 6 have been studied in experimental material. (bl.uk)
  • Because previous electron microscope studies have been mostly of sensory or parietal cortical areas the emphasis throughout this study has been on the structure and connections of the motor cortex and the somatic sensory cortex has been studied primarily to give a comparison with a different cortical area. (bl.uk)
  • The general ultrastructural appearance of the motor cortex and area 3b of the somatic sensory cortex is remarkably similar. (bl.uk)
  • focal
  • In the present study the investigators will conduct experiments on subjects with task specific focal hand dystonia (such as writers cramp) using TMS to decrease unwanted motor activity. (clinicaltrials.gov)
  • This thesis evaluates mice subjected to permanent or temporary occlusion focal motor cortex strokes in a skilled reaching task. (uleth.ca)
  • The second experiment is identical but uses a temporary occlusion focal motor cortex stroke. (uleth.ca)
  • axons
  • Layer I of both cortical areas contains a plexus of myelinated axons which was shown by light and electron microscopy to be markedly more dense in the motor cortex than in the somatic sensory cortex, although the diameters of the myelinated axons in both areas were similar. (bl.uk)
  • There is a considerable increase in the number of myelinated axons at and below this level in the cortex and in sections of layer IV cut parallel to the pial surface the apical dendrites which run vertically through layer IV may be seen to occur in bundles of six to twelve dendrites. (bl.uk)
  • modulation
  • Plewnia C, Bartels M, Cohen L, Gerloff C. Noradrenergic modulation of human cortex excitability by the presynaptic alpha(2)-antagonist yohimbine. (springer.com)