• This post-translational modification on lysine residues of proteins plays a crucial role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction. (nih.gov)
  • Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. (nih.gov)
  • The AP-1B clathrin adaptor complex plays a key role in the recognition and intracellular transport of many membrane proteins destined for the basolateral surface of epithelial cells. (rupress.org)
  • basolateral transport of proteins containing dileucine targeting motifs that do not interact with AP-1B were targeted normally despite overexpression of mutant Rab8. (rupress.org)
  • To a large extent, plasma membrane proteins are delivered to and maintained at the appropriate cell surface domain by distinct targeting signals that control polarized transport on the secretory and endocytic pathways ( Mellman, 1996 ). (rupress.org)
  • Despite the fact that AR binding in 22RV1 cells is comparatively weak in contrast to C4 2B cells, both typical and cell type specific AR binding events have been observed. (peptidesolubility.com)