Morbidity and mortality associSequentialPredictionMechanical ventilationRenalSeverityClinicalHospital MortalityRespiratory FailureQSOFAPatientsComplicationsNecrosisInfectionRiskOverall mortality rateSeptic shockIncidenceHighRateExcess mortalityAdmissionPredictSeverePhysiologicalPrevalenceExponentialHigherHospitalizationDysfunction ScoresPersistentAcidosisAntibioticsSystemicResuscitationCharacteristicsIndependently associated
Morbidity and mortality associ1
Sequential9
- Mortality Risk Using a Pediatric Quick Sequential (Sepsis-Related) Organ Failure Assessment Varies With Vital Sign Thresholds. (bvsalud.org)
- We evaluated adapting the quick Sequential ( Sepsis -Related) Organ Failure Assessment score (fast respiratory rate , altered mental status, low blood pressure ) for pediatric use by selecting thresholds from three commonly used definitions Pediatric Logistic Organ Dysfunction 2, Pediatric Advanced Life Support, and International Pediatric Sepsis Consensus Conference. (bvsalud.org)
- Among critically ill children who had a discharge diagnosis of infection in the PICU, quick Sequential ( Sepsis -Related) Organ Failure Assessment score performs best when using the Pediatric Logistic Organ Dysfunction 2 age thresholds with mechanical ventilation , while all definitions performed worse at extremes of pediatric age. (bvsalud.org)
- SOFA, Sequential Organ Failure Assessment. (cdc.gov)
- This study aimed to assess the value of quick sequential organ failure assessment (qSOFA) combined with other risk factors in predicting in-hospital mortality in patients presenting to the emergency department with suspected infection. (elsevierpure.com)
- Sequential organ failure assessment scores were similar in MICs and HICs. (lu.se)
- In a classic 1975 editorial by Baue, the concept of "multiple, progressive or sequential systems failure" was formulated as the basis of a new clinical syndrome. (medscape.com)
- Sequential Organ Failure Assessment Outperforms Quantitative Chest CT Imaging Parameters for Mortality Prediction in COVID-19 ARDS. (cdc.gov)
- Now, this has been changed a bit so that there is a SOFA [sequential organ failure assessment] calculator. (medscape.com)
Prediction3
- The idea, an artificial intelligence-powered risk prediction tool for organ failure, was pitched to a judging panel on Tuesday night at the virtual competition final. (imperial.ac.uk)
- We deployed a cosine-similarity-based patient similarity metric (PSM) to an intensive care unit (ICU) database to identify patients that are most similar to each patient and subsequently to custom-build 30-day mortality prediction models. (plos.org)
- BAP-65 prediction of in-hospital mortality and need for mechanical ventilation in COPD Predicts risk of mortality and need for mechanical ventilation in acute exacerbations of COPD. (bmj.com)
Mechanical ventilation5
- Area under the receiver operating characteristics curve (95% CI) was 0.760 (0.749-0.771) for Pediatric Logistic Organ Dysfunction 2 with mechanical ventilation , 0.700 (0.689-0.712) for Pediatric Advanced Life Support, and 0.709 (0.696-0.721) for International Pediatric Sepsis Consensus Conference. (bvsalud.org)
- Thus, mortality risk varies with vital sign thresholds, and although Pediatric Logistic Organ Dysfunction 2 with mechanical ventilation performed marginally better, it is unlikely to be of use to clinicians. (bvsalud.org)
- We aimed to explore the association between exposure to different intensities of oxygen exposure over time and 28-day mortality in patients with mechanical ventilation. (biomedcentral.com)
- Therefore, our primary objective was to estimate the effect of time-varying exposure to different intensities of oxygen exposure (as measured either by PaO 2 or FiO 2 ) on 28-day mortality in patients with mechanical ventilation. (biomedcentral.com)
- DESIGN-- We created an electronic health record-based surveillance definition for severe sepsis using clinical indicators of infection (blood culture and antibiotic orders) and concurrent organ dysfunction (vasopressors, mechanical ventilation, and/or abnormal laboratory values). (cdc.gov)
Renal11
- Elevated plasma vitamin B12 concentrations were identified as predictors of mortality in patients with oncologic, hepatic and renal diseases, and in elderly and critically ill medical patients. (mdpi.com)
- Acute renal failure (ARF) is a frequent tients who required kidney biopsy. (who.int)
- Cases were divided into community-ac- spite substantial advances in renal replace- quired ARF, defined as renal failure devel- ment therapy and health care delivery, oping outside the hospital, and hospital- morbidity and mortality rates associated acquired ARF, defined as renal failure that with ARF have remained high [ 1-3 ]. (who.int)
- Snakebite, malaria, liver diseases and Multivariate logistic regression analysis road traffic accidents are common health was carried out to study potential factors problems in Saudi Arabia [ 7-9 ], and the that might affect survival of acute renal contribution of these conditions to the de- failure. (who.int)
- This report was undertaken to tion, duration of renal failure and having study the pattern of ARF in hospitalized pa- concomitant liver disease were included tients in southern Saudi Arabia. (who.int)
- Diagnostics: malignant hypernatremia with a high plasma osmolarity associated with an acute anuric renal failure, hydro electrolytic disorders, an abnormal liver function, a fever of central origin and a stroke. (scirp.org)
- In a country with very limited resources, the severe hypernatremia prognosis associated with anuric acute renal failure may be favorable in the absence of renal replacement. (scirp.org)
- We report the case of a patient with extreme hypernatremia associated with acute anuric renal failure and multiple organ failure treated with hypo and isotonic solutions. (scirp.org)
- Severe acute pancreatitis is associated with persistent organ failure (cardiovascular, respiratory, and/or renal), and high mortality. (medscape.com)
- Renal (71.4%), hepatic (69.6%) and hemodynamic (62.5%) failures were the most common. (bvsalud.org)
- Deaths occurred beyond 24 hours of hospitalization (75%), in patients with comorbidities (65.6%), peritonitis (59.4%), hemodynamic (81.2%) and renal (75%) failures. (bvsalud.org)
Severity6
- Patients with De Ritis ratio ≥ 1.218 were significantly associated with mortality, severity, higher AST and IL-6, however with lower ALT. (researchsquare.com)
- Hospital mortality adjusted for severity (sepsis severity score), ICU admission source (emergency department, ward, vs ICU), and geographic region increased steadily after 1 hour of time to antibiotic administration. (researchgate.net)
- MODS scores can be used to assess the presence and severity of organ dysfunction on admission and throughout the stay [ 9 ]. (springer.com)
- Bedside Index of Severity in Acute Pancreatitis (BISAP) Score Predicts risk of mortality in acute pancreatitis. (bmj.com)
- Severity was first determined using Atlanta classification by the presence of organ failure. (bestbets.org)
- Interpretation: Despite similar disease severity and ventilation management, ICU mortality in patients without ARDS is higher in MICs than in HICs, with a strong association with country-level economic status. (lu.se)
Clinical15
- When lactate clearance is incorporated into clinical decision-making, it may improve sepsis mortality compared with early goal-directed therapy. (aafp.org)
- African Medical Journal describing its use of service claims data to patient investigation and treatment, as well as providing a framework determine standardised mortality rates, across hospital systems, for against which clinical outcomes can be measured. (who.int)
- Complicated disease courses in particular still represent a major clinical challenge and are associated with high mortality. (thieme-connect.com)
- Early clinical diagnosis is key-as treatment within the first 5 days of illness has been associated with lower mortality. (cdc.gov)
- In a general pediatric intensive care unit (PICU) population, the PEdiatric Logistic Organ Dysfunction-2 score (PELOD-2) score had both a good discrimination and calibration, allowing to describe the clinical outcome of critically ill children throughout their stay. (springer.com)
- The study, "Use of Electronic Clinical Data to Track Incidence and Mortality for SARS-CoV-2-Associated Sepsis", was published in JAMA Network Open. (nepalnews.com)
- Our prior research has shown that electronic health record (EHR)-based surveillance using clinical markers of infection and organ dysfunction can provide more accurate estimates of sepsis incidence and outcomes compared to using hospital discharge diagnosis codes, but this method had not previously been applied specifically for sepsis associated with SARS-CoV-2 or other viruses. (nepalnews.com)
- The team quantified the incidence and in-hospital mortality for sepsis associated with SARS-CoV-2 infections using clinical criteria adapted from CDC's sepsis surveillance definition that incorporated positive SARS-CoV-2 tests and clinical signs of organ dysfunction. (nepalnews.com)
- The primary outcome was clinical improvement, while the secondary outcomes were the development of systemic inflammatory response syndrome (SIRS) and multiple organ dysfunction syndrome (MODS), relief of epigastric abdominal pain, and length of hospital stay (LoH). (frontiersin.org)
- The degree of organ dysfunction has a major clinical impact. (medscape.com)
- [ 1 ] Several different terms were proposed thereafter (eg, multiple organ failure, multiple system organ failure, and multiple organ system failure) to describe this evolving clinical syndrome of otherwise unexplained progressive physiologic failure of several interdependent organ systems. (medscape.com)
- MODS is defined as a clinical syndrome characterized by the development of progressive and potentially reversible physiologic dysfunction in 2 or more organs or organ systems that is induced by a variety of acute insults, including sepsis. (medscape.com)
- The clinical process usually begins with infection, which potentially leads to sepsis and organ dysfunction. (medscape.com)
- OBJECTIVE-- To compare the accuracy of surveillance of severe sepsis using electronic health record clinical data vs claims and to compare incidence and mortality trends using both methods. (cdc.gov)
- We then estimated and compared changes in severe sepsis incidence and mortality rates using the clinical vs claims-based surveillance definitions. (cdc.gov)
Hospital Mortality17
- Prospective data from nearly 20,000 patients in the Surviving Sepsis Campaign demonstrated that a single serum lactate level greater than 4.0 mmol per L in the presence of hypotension is associated with higher in-hospital mortality (odds ratio = 1.64) compared with either a serum lactate level of 4.0 mmol per L or less or the absence of hypotension. (aafp.org)
- In-hospital mortality associated with IABP was examined in each SCAI shock stage. (getinge.com)
- Multivariable logistic regression was performed using inverse probability of treatment weighting (IPTW) to determine the association between IABP and in-hospital mortality. (getinge.com)
- 05, except p = .08 in SCAI shock stage E). We did not observe any significant heterogeneity in the association between IABP use and in-hospital mortality as a function of SCAI shock stage. (getinge.com)
- IABP use was associated with substantially lower in-hospital mortality in patients with CS, without differences in this effect across the SCAI shock stages. (getinge.com)
- The association between vitamin B12 concentrations and in-hospital mortality in adult patients at nutritional risk has not been assessed. (mdpi.com)
- Methods We used standardized hospital discharge data provided by the Federal Statistical Office of Germany to evaluate hospital mortality and current developments of AP in Germany between 2008 and 2017. (thieme-connect.com)
- Average hospital mortality was 2.85% and significantly improved over time. (thieme-connect.com)
- Hospital mortality was significantly higher in female patients (3.31%) than males (2.55%) and showed a stepwise increase with patient age. (thieme-connect.com)
- We further identified type 2 diabetes mellitus and obesity as factors associated with increased hospital mortality. (thieme-connect.com)
- Hospital mortality was lowest among patients treated at departments specializing in gastroenterology. (thieme-connect.com)
- 98 annual AP cases) had the lowest hospital mortality for patients with complicated courses of AP. (thieme-connect.com)
- Antibiotic administration and hospital mortality. (researchgate.net)
- In-hospital mortality was 29.7% for the cohort as a whole. (researchgate.net)
- The results of the analysis of this large population of patients with severe sepsis and septic shock demonstrate that delay in first antibiotic administration was associated with increased in-hospital mortality. (researchgate.net)
- This study was designed to develop a predictive score for in-hospital mortality for cardiogenic shock patients who received VA-ECMO after isolated CABG. (biomedcentral.com)
- The REMEMBER score might help clinicians at bedside to predict in-hospital mortality for patients receiving VA-ECMO after isolated CABG for refractory cardiogenic shock. (biomedcentral.com)
Respiratory Failure4
- Under-The-Nose Versus Over-The-Nose Face Mask to Prevent Facial Pressure Sores During Face Mask-Delivered Noninvasive Ventilation for Acute Hypercapnic Respiratory Failure: A Randomized Controlled Trial. (medscape.com)
- When tachypnea and pending respiratory failure develops, intubation should be performed. (medscape.com)
- 18 years, venovenous ECMO support for acute respiratory failure, ECMO initiation before CABG or at more than 7 days after CABG, and concomitant other major cardiac procedures (valvular replacement, valvuloplasty, or aortic surgery). (biomedcentral.com)
- Mucous membrane involvement can result in gastrointestinal hemorrhage, respiratory failure, ocular abnormalities, and genitourinary complications. (medscape.com)
QSOFA2
- https://www.mdcalc.com/qsofa-quick-sofa-score-sepsis ) scores are routinely used for screening and identifying patients at higher risk of sepsis mortality. (aafp.org)
- A retrospective cohort study of 1,865 adults with sepsis found that average lactate scores within the first 24 hours of hospital admission had a higher sensitivity, similar specificity, and greater area under the receiver operating characteristic curve (AUROC) than qSOFA for predicting 30-day mortality. (aafp.org)
Patients24
- The causes of death in the study were consistent with those expected in patients with septic shock, although there was a higher proportion of cardiovascular deaths and a lower incidence of deaths caused by multiple organ failure in the 546C88 group. (nih.gov)
- In this study, the nonselective nitric oxide synthase inhibitor 546C88 increased mortality in patients with septic shock. (nih.gov)
- 1 Elevated serum lactate levels are associated with increased mortality, and guidelines recommend using lactate measurement to guide management in these patients. (aafp.org)
- Mortality in patients presenting with sepsis rises linearly with increasing serum lactate levels. (aafp.org)
- Lactate clearance is often delayed in patients with hepatic failure and may not be a reliable prognostic marker in these patients. (aafp.org)
- An initial lactate level of greater than 4.0 mmol per L can be used to identify patients with sepsis who are at higher risk of mortality. (aafp.org)
- Although a lactate level greater than 4.0 mmol per L clearly correlates with higher mortality in patients with sepsis, lactate levels between 2.0 and 4.0 mmol per L are often incorrectly used to identify septic shock, which could lead to overdiagnosis and the unnecessary initiation of aggressive treatment. (aafp.org)
- We examined the association between IABP and mortality in CS patients across the Society for Cardiovascular Angiography and Intervention (SCAI) shock stages. (getinge.com)
- Cette étude a permis de déterminer la fréquence et l'étiologie de l'insuffisance rénale aiguë chez des patients hospitalisés en Arabie saoudite sur une période de 2 ans. (who.int)
- It is a major cause of maternal and neonatal morbidity and mortality in low- and middle-income countries and affects millions of hospitalized patients in high-income countries, where rates of sepsis are climbing rapidly. (who.int)
- Heart transplant patients from socioeconomically distressed communities face 10% higher mortality and organ failure risk than non-distressed communities. (medindia.net)
- Compelling evidence has shown that aggressive resuscitation bundles, adequate source control, appropriate antibiotic therapy, and organ support are cornerstone for the success in the treatment of patients with sepsis. (researchgate.net)
- Results were similar in patients with severe sepsis and septic shock, regardless of the number of organ failure. (researchgate.net)
- Mortality for patients who require operative intervention is very high, up to 80% in some series. (lww.com)
- PICO [population, intervention, comparison, and outcome] Question 1: In adult patients with CDAD, does early surgery compared with late surgery, as defined by the need for vasopressors, decrease mortality? (lww.com)
- PICO Question 2: In adult patients with CDAD, does total abdominal colectomy (TAC) compared with other types of surgical intervention decrease mortality? (lww.com)
- Early identification of pre-ECMO factors associated with mortality may prognosticate in post-CABG patients. (biomedcentral.com)
- We developed the pRedicting mortality in patients undergoing veno-arterial Extracorporeal MEMBrane oxygenation after coronary artEry bypass gRafting (REMEMBER) score, which might help the clinicians to select patients that would benefit from VA-ECMO after CABG. (biomedcentral.com)
- Patients in MICs were younger, shorter and with a slightly lower body-mass index, more often had diabetes and active cancer, but less often chronic obstructive pulmonary disease and heart failure than patients from HICs. (lu.se)
- The mortality rate for patients with SARS-CoV-2-associated sepsis was very high initially-33% over the first three months of the pandemic-but declined over time and eventually became similar to the mortality rate for presumed bacterial sepsis, a rate of about 14.5% that remained stable throughout the study period. (nepalnews.com)
- 2 , 3 Although pregnant women can have other hypertensive conditions along with preeclampsia, preeclampsia is defined as new-onset hypertension (or, in patients with existing hypertension, worsening hypertension) occurring after 20 weeks of gestation, combined with either new-onset proteinuria (excess protein in the urine) or other signs or symptoms involving multiple organ systems. (aafp.org)
- Early transfer of patients to a burn or intensive care unit has been shown to reduce the risk of infection, mortality rate, and length of hospitalization. (medscape.com)
- Il s'agit d'une étude transversale, monocentrique et descriptive, durant 12 mois, incluant les patients âgés d'au moins 18 ans admis en réanimation polyvalente pour un sepsis ou choc septique. (bvsalud.org)
- However, there is a rather complex concept in this document about combination therapy for the sickest patients with scores indicating a 25% mortality. (medscape.com)
Complications7
- Moderately severe: distinguished by the presence of transient organ failure, locoregional as well as systemic complications, and/or transient organ failure. (medscape.com)
- Severe: characterized by persistent organ failure and locoregional as well as systemic complications. (medscape.com)
- Complications include dehydration, sepsis, pneumonia and multiple organ failure. (wikipedia.org)
- The significance of occult hypoperfusion (OH) in the development of respiratory complications (RC), multiple system organ failure (MSOF), and death, and the effect of rapid identification and correction of OH in the severely injured trauma patient was investigated. (nih.gov)
- This helps avoid the potential complications of invasive ventilation, which can reduce the length of stay, and may decrease mortality in the ICU. (draeger.com)
- Studies have also shown that fluid resuscitation is beneficial for lowering mortality and the occurrence of complications such as pancreatic necrosis and organ failure ( 10 ). (frontiersin.org)
- It is the second leading cause of maternal mortality worldwide 7 , 8 and may also lead to other serious maternal complications, including stroke, eclampsia, and organ failure. (aafp.org)
Necrosis1
Infection9
- We examined their respective performance in identifying children who had a discharge diagnosis of infection at high risk of mortality using PICU registry data , with additional focus on the influence of age on performance. (bvsalud.org)
- Sepsis arises when the body's response to infection injures its own tissues and organs. (who.int)
- Appropriate treatment of sepsis requires not only treatment of the underlying infection, but in parallel requires life-saving medical interventions such as fluid resuscitation or vital organ support. (who.int)
- In 2016, the Third International Consensus Definitions Task Force (Sepsis-3) defined sepsis as 'life-threatening organ dysfunction due to a dysregulated host response to infection. (medicinenet.com)
- Pneumonia is the second most common nosocomial infection in the United States and is associated with substantial morbidity and mortality. (cdc.gov)
- Severe infection that results in organ failure is referred to as sepsis. (nepalnews.com)
- Sepsis occurs when the body's response to infection goes into overdrive, leading to tissue damage, organ failure, and death. (acsh.org)
- Use of one to three doses of a Top 1 inhibitor that is 1/50th the strength of normal chemotherapy was enough to rescue 70-90 % of mice from what is known as a cytokine, or inflammatory, storm death due to either acute bacterial infection, liver failure, or virus-bacteria co-infection. (acsh.org)
- Author Manuscript reviewed 1,000 randomly selected medical charts to characterize the definition's accuracy and stability over time compared with a claims-based definition requiring infection and organ dysfunction codes. (cdc.gov)
Risk10
- Older adults, young children, and persons with chronic medical conditions are particularly susceptible to these illnesses and are at high risk for heat-related mortality ( 2 ). (cdc.gov)
- A meta-analysis of a single randomized controlled trial and five prospective observational studies including a total of 927 adults with sepsis found that the relative risk of mortality associated with lactate clearance was 0.41 (95% CI, 0.28 to 0.60). (aafp.org)
- In 2019, Discovery Health published a risk adjustment model to determine standardised mortality rates across South African private hospital systems, with the aim of contributing towards quality improvement in the private healthcare sector. (who.int)
- The De Ritis ratio proved to be an independent risk factor for mortality with an OR of 29.967 (CI 5.266-170.514). (researchsquare.com)
- Liver cirrhosis is a high risk factor for COVID-19 mortality. (researchsquare.com)
- Delay in the initiation of appropriate antibiotic therapy has been recognized as a risk factor for mortality. (researchgate.net)
- In addition, there was a linear increase in the risk of mortality for each hour delay in antibiotic administration. (researchgate.net)
- Reduction in mortality was significantly associated with early surgery, with a risk ratio (RR) of 0.5 (95% confidence interval [CI], 0.35-0.72). (lww.com)
- More importantly, uncontrolled systemic inflammation is a major role in the emergence of organ failure, a condition that was previously associated with a higher risk of mortality ( 9 ). (frontiersin.org)
- Bunker's bible," as it was nicknamed, provided surgeons with easy-to-use tables and decision trees that summarized mortality rates, age-related risk assessments and quality-of-life impacts for the most common surgical procedures. (stanford.edu)
Overall mortality rate2
Septic shock2
- It can lead to septic shock, multiple organ failure and death, if not recognized early and managed promptly. (who.int)
- The final stage of sepsis can lead to septic shock, multiple organ failure, and death. (kth.se)
High8
- Circulatory shock is a life-threatening syndrome resulting in multiorgan failure and a high mortality rate. (springer.com)
- Although advances in the treatment and options for small-bowel perforations have occurred, the mortality rate can still be high. (ispub.com)
- Without proper and prompt treatment with dantrolene sodium, mortality is extremely high. (sciencedaily.com)
- Finally, we aimed to identify the direct and indirect effects of high FiO 2 on mortality. (biomedcentral.com)
- The SCT is widespread in the WHO African Region;3 the S gene prevalence in at least 40 countries varies between 2% and 30%, resulting in high SCD-related morbidity and mortality. (who.int)
- He also assembled a large body of data on operations and operative mortality, questioning the high rates of surgical procedures in the United States and suggesting that financial incentives could be unduly influencing medical decision-making. (stanford.edu)
- The mortality is very high. (bvsalud.org)
- This is a rather complex equation in which you enter data to see whether the patient is heading into trouble with high mortality. (medscape.com)
Rate4
- Is my rate of heart failure readmissions artery bypass graft (CABG) surgery, pneumonia and acute stroke). (who.int)
- and others report a mortality rate of between 28% and 42% during the 1970s 1,3 while Kan Tan et al. (ispub.com)
- report a mortality rate of 19.1% in 2008 2 . (ispub.com)
- Observed mortality rate was 26.9 % (119/443). (springer.com)
Excess mortality1
Admission2
- Meanwhile, previous studies focused on only the association between PaO 2 or FiO 2 during the early onset of illness and mortality, usually within 24 h after ICU admission, and many of these studies are limited by using only a single measure of PaO 2 or FiO 2 to define oxygen exposure for entire ICU admission. (biomedcentral.com)
- At admission, the median number of organ failures per patient was three (maximum 5). (bvsalud.org)
Predict2
- Lactate clearance, defined as the reduction of lactate over time, may also be useful to predict mortality. (aafp.org)
- Multivariate binary logistic regression and Receiver Operating Characteristic (ROC) curves were performed to evaluate the impact of abnormal laboratory findings to predict mortality. (researchsquare.com)
Severe2
- We report a case of ecstasy toxicity with severe multiple organ failure, who went on to make a full recovery after prolonged hospitalization. (erowid.org)
- 40 patient were classified as severe acute pancreatitis based on the presence of organ failure for more than 48h. (bestbets.org)
Physiological1
- Organ dysfunction scores, based on physiological parameters, have been created to describe organ failure. (springer.com)
Prevalence1
- Success in implementing identified interventions will depend on the commitment of Member States to integrate SCD prevention and control in national health plans, and provide an environment conducive for various stakeholders to contribute to the reduction of SCD prevalence, morbidity and mortality. (who.int)
Exponential1
Higher2
Hospitalization1
- Sepsis is treated with hospitalization, intravenous antibiotics, and therapy to support any organ dysfunction. (medicinenet.com)
Dysfunction Scores1
- However, some authors have voiced their concern regarding using organ dysfunction scores in specific subpopulations [ 9 ]. (springer.com)
Persistent1
- Whether the association between time-varying oxygen exposure and mortality is significant and remains persistent over time is unknown. (biomedcentral.com)
Acidosis1
- Concomitant organ dysfunction or perfusion abnormalities (eg, lactic acidosis, oliguria, and coma) are present in the absence of other known causes. (medscape.com)
Antibiotics1
- This is based on an observational study [ 2 ] from more than 10 years ago and others, and is biologically plausible, although a meta-analysis [ 3 ] showed no difference in mortality between people receiving antibiotics within 3 hours versus 1 hour. (medscape.com)
Systemic1
- Most of the events accounting for the disparity between the groups were associated with the cardiovascular system (e.g., decreased cardiac output, pulmonary hypertension, systemic arterial hypertension, heart failure). (nih.gov)
Resuscitation1
- 10 Resuscitation guided by lactate clearance is not superior in reducing mortality compared with resuscitation guided by monitoring of capillary refill time. (aafp.org)
Characteristics1
- The performance in predicting observed mortality was assessed for the three candidate approaches using receiver operating characteristics analysis , including age group effects. (bvsalud.org)