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  • Multi-Organ Failure
  • Abdominal compartment syndrome is a clinical picture in which there is an increased intra-abdominal pressure causing a deterioration in abdominal perfusion of intra-abdominal organs that eventually results in intra- and extra-abdominal multi-organ failure and death. (ebscohost.com)
  • cytokine
  • We have previously demonstrated that Mkp-1 −/− mice exhibit exacerbated inflammatory cytokine production and increased mortality in response to challenge with LPS and heat-killed Staphylococcus aureus . (jimmunol.org)
  • These MAPKs regulate immune responses at multiple levels, including facilitation of Ag presentation and induction of cytokine expression ( 12 ). (jimmunol.org)
  • Chan hopes his company, CytoSorbents, has finally discovered a good way to make the cytokine storm abate and has recently moved closer to the all-important tests on humans in the United States to see if the treatment can help prevent organ failure. (princetoninfo.com)
  • ARDS
  • The objective of the present study was to evaluate the role of oxidative stress, alveolar antioxidant status and multiple organ injury in ARDS induced by lipopolysaccharide (LPS) in rats. (niscair.res.in)
  • tissues
  • In LPS-treated rats, we observed increased levels of oxidative products, decreased levels of antioxidants in lung tissues and increased levels of serum marker enzymes, suggesting multiple organ injury. (niscair.res.in)
  • Despite
  • Despite the provocative findings, these studies were limited by small sample size and short-term follow-up, leaving the relationship between cholesterol, lipoproteins, and mortality in HF far from established. (onlinejacc.org)
  • Despite significant advances made, the mortality associated with ALI remains unchanged. (niscair.res.in)
  • serum
  • Elevated serum cholesterol levels were also a risk factor for the development of heart failure (HF) in the Framingham study (2) . (onlinejacc.org)
  • treatment
  • The origin and geographic spread of this drug resistance have been inferred mainly from records of clinical resistance (treatment failure). (ajtmh.org)
  • response
  • Once inside the host, pathogenic strains can evade the innate immune response, multiply, and spread to most internal organs via the bloodstream ( 1 ). (asm.org)