Cell AgingCyclin-Dependent Kinase Inhibitor p16Telomerebeta-GalactosidaseAging, PrematureCyclin-Dependent Kinase Inhibitor p21TelomeraseBiological ProcessesTumor Suppressor Protein p53AgingTelomere ShorteningCells, CulturedFibroblastsCell ProliferationDNA DamageOxidative StressSignal TransductionReactive Oxygen SpeciesRetinoblastoma ProteinApoptosisCell Line, TumorEndothelial CellsCell CyclePhenotypeTOR Serine-Threonine KinasesCell DivisionRNA InterferenceUp-RegulationTime FactorsGene Expression RegulationRNA, Small InterferingDown-RegulationStem CellsCell LineBlotting, WesternPlant LeavesHistonesp38 Mitogen-Activated Protein KinasesMice, Inbred C57BLCell DifferentiationReverse Transcriptase Polymerase Chain ReactionMice, KnockoutEndothelium, VascularCell Cycle ProteinsFlow CytometryAtherosclerosisDNA-Binding ProteinsTransfectionGene Expression Regulation, NeoplasticImmunohistochemistryBiological MarkersDose-Response Relationship, DrugPhosphorylationRNA, MessengerEnzyme ActivationGene Expression Regulation, PlantEthylenesMutationCell Transformation, NeoplasticMicroscopy, Electron, ScanningChlorophyllArabidopsisFlowersLongevityTumor Suppressor Protein p14ARFModels, BiologicalCell Cycle CheckpointsPlant ProteinsPlant Growth RegulatorsPlants, Genetically ModifiedTumor Suppressor ProteinsMicroscopy, ElectronArabidopsis ProteinsMolecular Sequence DataSirtuin 1CytokininsPetuniaNuclear ProteinsDiploidyras ProteinsTranscription FactorsCell SizeCell Line, TransformedNeoplasmsReproductionHydrogen PeroxideEpithelial CellsProgeriaCyclopentanesPlant StemsCell SurvivalGene Expression ProfilingGene Knockdown TechniquesBiological EvolutionTelomeric Repeat Binding Protein 2DarknessGenes, rasGene ExpressionMitochondriaMicroscopy, Electron, Transmission