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  • dose
  • Do not use more than the recommended dose of morphine, and avoid activities requiring mental alertness such as driving or operating hazardous machinery until you know how the medication affects you. (drugs.com)
  • Each bead contains a dose of naltrexone, which counteracts the effects of morphine if the drug is taken incorrectly (such as if it is crushed or dissolved in order to snort or inject the medication). (emedtv.com)
  • In the setting of breathlessness at rest or on minimal exertion from conditions such as advanced cancer or end-stage cardiorespiratory diseases, regular, low-dose sustained-release morphine significantly reduces breathlessness safely, with its benefits maintained over time. (wikipedia.org)
  • Low-dose naltrexone (LDN) describes the off-label use of the medication naltrexone at low doses for diseases such as multiple sclerosis. (wikipedia.org)
  • Some proponents of low-dose naltrexone have brought forth claim about its efficacy in treating a wide range of diseases, including cancer and HIV/AIDS. (wikipedia.org)
  • Low-dose naltrexone organizations have promoted its use on their webpages. (wikipedia.org)
  • Low-dose naltrexone refers to doses at about 1/10th the size of the dose used normally. (wikipedia.org)
  • Organizations promoting low-dose naltrexone have advocated it as a treatment for a variety of medical conditions. (wikipedia.org)
  • However, currently no peer-reviewed studies that would justify clinical use of low-dose naltrexone in treating Multiple Sclerosis (MS) have been published. (wikipedia.org)
  • Low-dose naltrexone may relieve certain symptoms in people with multiple sclerosis, although medical practitioners often advise against using it as a substitute to proven therapies, and the evidence supporting its use in MS is not robust, as different studies have come to conflicting conclusions. (wikipedia.org)
  • Writing for the National MS Society in 2009, neurologist Alan Bowling called research into low-dose naltrexone "encouraging" but further research needed to be done before any definitive conclusions could be reached. (wikipedia.org)
  • Bowling noted that safety of low-dose naltrexone treatment for multiple sclerosis has not been assessed, and that patients who chose to undergo the treatment should be fully informed of the limited research backing its use. (wikipedia.org)
  • Personal testimonials describing low-dose naltrexone as a cure for multiple sclerosis are not supported by high quality evidence in large randomised, double-blind, placebo-controlled clinical trials. (wikipedia.org)
  • The UK National Health Service concluded that small pilot studies indicate low-dose naltrexone can improve symptoms in multiple sclerosis patients, but that more thorough studies are needed to determine its efficacy and safety. (wikipedia.org)
  • Prescription and medical formulation of low-dose naltrexone in the UK are unlicensed in the treatment of multiple sclerosis. (wikipedia.org)
  • One small pilot study found a reduction in fibromyalgia symptoms in patients treated with low-dose naltrexone. (wikipedia.org)
  • In addition to proposed uses for low-dose naltrexone that have been studied in clinical research, low-dose naltrexone advocates make unproven claims of its efficacy in treating other conditions, including: various types of cancer, Alzheimer's disease, HIV/AIDS, rheumatoid arthritis, and others. (wikipedia.org)
  • Constipation
  • One of his patients, struggling with the pain of prostatic cancer that had metastasized to his bones, was now declining the morphine he required for analgesia because of constipation. (wikipedia.org)
  • alcohol
  • Do not use alcohol or medications that contain alcohol while you are receiving treatment with morphine. (drugs.com)
  • If you are taking certain long-acting formulations of morphine, consumption of alcohol may also cause rapid release of the drug, resulting in high blood levels that may be potentially lethal. (drugs.com)
  • side effects
  • Researchers have also examined "ultra-low-doses" of naltrexone at microgram, nanogram, and picogram doses, that are co-administered with opioid analgesics with the goal of increasing pain relief and reducing side effects. (wikipedia.org)
  • In addition, nalmexone's side effects, the most common of which were sleepiness and sweating, were reported to be similar to those of morphine, albeit with a noticeably higher degree of incidence. (wikipedia.org)