Dendritic cellsProteinProteinsMacrophagesNeutrophilsEosinophilsCytokineBindsChemokineCytokinesReactivityInducesCellsSecretionInterleukinLymphocytesEpithelialSpeciesEndothelialAssayChemotaxisNeutrophilReconstitutionAminoAntigenAntibodyLigandCatalogEnzymeSequenceErythropoietinCCL7VaccineImmunodeficiency virusConcentration rangeCellInfectEndotoxinFunctionalInflammatoryAntimicrobialBloodGeneReceptors
Dendritic cells10
- HVEM is highly expressed on naïve CD4+ T cells, CD8+ T memory cells, regulatory T cells, dendritic cells, monocytes, and neutrophils (4-8). (rndsystems.com)
- Interleukin 3 (IL-3) stimulates multipotent stem cells and differentiated hematopoietic progenitor cells, promoting their differentiation and proliferation into basophils, mast cells, type-1 and -2 dendritic cells, eosinophils and monocytes. (fujifilm.com)
- Large-scale immunomagnetic selection of CD14+ monocytes to generate dendritic cells for cancer immunotherapy: a phase I study. (nwbio.com)
- Maturation and trafficking of monocyte-derived dendritic cells in monkeys: implications for dendritic cell-based vaccines. (nwbio.com)
- Vaccination of prostatectomized prostate cancer patients in biochemical relapse, with autologous dendritic cells pulsed with recombinant human PSA. (nwbio.com)
- B7-H3 is widely expressed in both lymphoid and nonlymphoid organs at the transcriptional level, but the expression of B7-H3 protein is more restricted to cell types such as activated dendritic cells (DCs), monocytes, T cells, B cells, and NK cells. (medchemexpress.com)
- IL-27 is expressed by monocytes, endothelial cells and dendritic cells. (creativebiomart.net)
- Antigen gene transfer to cultured human dendritic cells using recombinant avipoxvirus vectors. (lookformedical.com)
- Advances in understanding the role of dendritic cells (DCs) as the major antigen (Ag)-presenting cell type of the immune system combined with the recent development of methods for the ex vivo expansion of human DCs have opened the possibility for the transfer of tumor Ags to DCs with a view toward tumor immunotherapy. (lookformedical.com)
- Defective migration of monocyte-derived dendritic cells in LAD-1 immunodeficiency. (lu.se)
Protein46
- Monocyte chemotactic protein 4 (MCP-4), a novel structural and functional analogue of MCP-3 and eotaxin. (rupress.org)
- The mature recombinant protein that was released had the NH2-terminal sequence pyro-QPDALNVPSTC. (rupress.org)
- The novel chemokine was designated monocyte chemotactic protein 4 (MCP-4) and the variants were designated (LA)MCP-4 and (FNPQGLA)MCP-4. (rupress.org)
- Recombinant Human BD-4 is a 6.0 kDa protein containing 50 amino acid residues. (peprotech.com)
- Murine CCL8, also known as monocyte chemotactic protein 2 (MCP-2), is belonging to the CC chemokine family and is encoded by the gene CCL8 in mouse. (watson-bio.cn)
- CF stands for Carrier Free (CF). We typically add Bovine Serum Albumin (BSA) as a carrier protein to our recombinant proteins. (rndsystems.com)
- Adding a carrier protein enhances protein stability, increases shelf-life, and allows the recombinant protein to be stored at a more dilute concentration. (rndsystems.com)
- In general, we advise purchasing the recombinant protein with BSA for use in cell or tissue culture, or as an ELISA standard. (rndsystems.com)
- When recombinant SARS-CoV-2 B.1.1.7 Spike Protein S1 is immobilized at 2 μg/mL, recombinant human ACE2-Fc Chimera (Cat. (biolegend.com)
- Recombinant SARS-CoV-2 B.1.1.7 Spike Protein S1 was aliquoted in PBS at 0.2 mg/mL. (biolegend.com)
- The 678 amino acid recombinant protein has a predicted molecular mass of approximately 76 kD. (biolegend.com)
- Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Monocyte Chemotactic Protein 3 (MCP3) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids. (pharmas-eu.org)
- Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Mouse Monocyte Chemotactic Protein 3 (MCP3) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids with no significant corss-reactivity with analogues from other species. (pharmas-eu.org)
- Description: A sandwich ELISA kit for detection of Monocyte Chemotactic Protein 3 from Mouse in samples from blood, serum, plasma, cell culture fluid and other biological fluids. (pharmas-eu.org)
- Description: A sandwich quantitative ELISA assay kit for detection of Rat Monocyte Chemotactic Protein 3 (MCP3) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids. (pharmas-eu.org)
- A novel oligosaccharide compound AVR-25 selectively binds to the TLR4 protein (IC 50 = 0.15 µM) in human peripheral blood monocytes and stimulates IL-10 production. (nature.com)
- NT3 upregulates cellular proliferation, extracellular matrix protein production, and collagen deposition in human aortic valve interstitial cells through the Trk-Akt-cyclin D1 cascade. (cusabio.com)
- Recombinant Human CCL7 protein( Gln 24 - Leu 99), fused with His tag, was expressed in HEK293. (creativebiomart.net)
- With hematopoiesis of IL-3, this protein is anticipated to be an effective treatment, in combination with chemotherapy, for myelodysplastic syndrome and aplastic anemia. (fujifilm.com)
- Discover the versatility of our Recombinant Human CCL5 protein, an essential tool for advancing immunological research. (cusabio.com)
- Our commitment to quality ensures that the Recombinant Human CCL5 protein boasts a purity of >98% as determined by SDS-PAGE and HPLC analysis. (cusabio.com)
- As such, our Recombinant Human CCL5 protein serves as a valuable tool in elucidating the molecular mechanisms underlying immune function and developing novel therapeutics for immune-related disorders [2] . (cusabio.com)
- Recombinant RANTES protein induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV). (cusabio.com)
- Recombinant human IL-16 is a 12.4 kDa protein consisting of 121 amino acid residues. (thomassci.com)
- B7 homolog 3 (B7-H3, also named CD276) is a type I transmembrane protein that belongs to the B7-CD28 family. (medchemexpress.com)
- CD276/ B7-H3 Protein, Human (HEK293, Fc) is a polypeptide chain containing the C-termimal His tag produced in HEK293 cells. (medchemexpress.com)
- CD276/ B7-H3 Protein, Human (HEK293, His) is a polypeptide chain containing the C-termimal His tag produced in HEK293 cells. (medchemexpress.com)
- The molecular structure of Fasciola gigantica 14-3-3 protein has been characterized. (biomedcentral.com)
- We report on the cloning and expression of a recombinant F. gigantica 14-3-3 epsilon protein (rFg14-3-3e), and testing its effects on specific functions of goat peripheral blood mononuclear cells (PBMCs). (biomedcentral.com)
- rFg14-3-3e protein was expressed in Pichia pastoris . (biomedcentral.com)
- Western blot and immunofluorescence assay (IFA) were used to examine the reactivity of rFg14-3-3e protein to anti- F. gigantica and anti-rFg14-3-3e antibodies, respectively. (biomedcentral.com)
- Various assays were used to investigate the stimulatory effects of the purified rFg14-3-3e protein on specific functions of goat PBMCs, including cytokine secretion, proliferation, migration, nitric oxide (NO) production, phagocytosis, and apoptotic capabilities. (biomedcentral.com)
- Potential protein interactors of rFg14-3-3e were identified by querying the databases Intact, String, BioPlex and BioGrid. (biomedcentral.com)
- Sequence analysis revealed that rFg14-3-3e protein had 100% identity to 14-3-3 protein from Fasciola hepatica . (biomedcentral.com)
- Western blot analysis showed that rFg14-3-3e protein is recognized by sera from goats experimentally infected with F. gigantica and immunofluorescence staining using rat anti-rFg14-3-3e antibodies demonstrated the specific binding of rFg14-3-3e protein to the surface of goat PBMCs. (biomedcentral.com)
- rFg14-3-3e protein stimulated goat PBMCs to produce interleukin-10 (IL-10) and transforming growth factor beta (TGF-β), corresponding with low levels of IL-4 and interferon gamma (IFN-γ). (biomedcentral.com)
- Also, this recombinant protein promoted the release of NO and cell apoptosis, and inhibited the proliferation and migration of goat PBMCs and suppressed monocyte phagocytosis. (biomedcentral.com)
- Homology modelling revealed 65% identity between rFg14-3-3e and human 14-3-3 protein YWHAE. (biomedcentral.com)
- Our data suggest that rFg14-3-3e protein can influence various cellular and immunological functions of goat PBMCs in vitro and may be involved in mediating F. gigantica pathogenesis. (biomedcentral.com)
- Because of its involvement in F. gigantica recognition by innate immune cells, rFg14-3-3e protein may have applications for development of diagnostics and therapeutic interventions. (biomedcentral.com)
- The human EBI3 gene encodes a 229 amino acid (aa) precursor that contains a 20 aa signal peptide and 209 aa mature protein. (creativebiomart.net)
- For this purpose, we constructed recombinant λ-phage nanobioparticles containing a mammalian expression cassette encoding enhanced green fluorescent protein (EGFP) and E7 gene of human papillomavirus type 16 (λ-HPV-16 E7) using Lambda ZAP- CMV XR vector. (biomedcentral.com)
- Anti-human TNF VHH Single Domain Antibody is a protein produced in E. coli. (creativebiolabs.net)
- We have recently conducted a first-in-human clinical trial to evaluate the safety and immunogenicity of the recombinant, full-length merozoite surface protein 1 (MSP1 FL ) formulated with GLA-SE as adjuvant. (nature.com)
- We previously reported a C. abortus (Cab) vaccine comprising recombinant Vibrio cholerae ghosts (rVCG) expressing the conserved and immunogenic N-terminal region of the Cab polymorphic membrane protein D (rVCG-Pmp18.1) protein that protected mice against intravaginal challenge. (cdc.gov)
- In this respect, in contrast to predictors based for each serum protein was determined by comparing the samples upon tumor characteristics at the time of surgery, serum is a par- collected at the primary operation and then 3-6 mo later. (lu.se)
Proteins3
- MCP-4 shares the pyroglutamic acidproline NH2-terminal motif and 56-61% sequence identity with the three known monocyte chemotactic proteins and is 60% identical to eotaxin. (rupress.org)
- The neurotrophin family is comprised of at least four proteins including NGF, BDNF, NT-3, and NT-4/5. (novusbio.com)
- The detection and evaluation of concentration of influenza virus proteins in biological samples is critical in a broad range of medical and biological investigations regarding the concern over potential outbreaks of virulent influenza strains in animals and humans. (omicsonline.org)
Macrophages8
- IL-28A produced in response to viral infection, activates both monocytes and macrophages producing a restricted panel of cytokines and therefore is an important factor in activating innate immune responses at the site of viral infection. (prospecbio.com)
- In addition, we found that the M. aurum infection of human THP1 macrophages modulates the expression of endogenous RNase3 and RNase6, suggesting a function in vivo . (frontiersin.org)
- Mtb is an intracellular pathogen able to survive indefinitely under unfavorable conditions inside primary host immune cells, preferably residing in human alveolar macrophages ( 5 , 6 ). (frontiersin.org)
- Using ex vivo models of primary MCL cells (n=23), we demonstrated that, through the secretion of IL32β, the tumor was able to polarize monocytes into specific MCL-associated macrophages, which in turn favor tumor survival. (haematologica.org)
- A greater number of alveolar macrophages produced TNF-α compared to autologous monocytes in sarcoidosis but not in controls and, based on cell size, it was confirmed that this was the product of more mature macrophages and that the secretion of TNF-α by monocytes and macrophages was heterogeneous: not all monocytes and macrophages secrete TNF-α. (ersjournals.com)
- No differences in the average levels of TNF-α secretion by peripheral blood monocytes or alveolar macrophages were observed. (ersjournals.com)
- So on day one, Session 1 will focus on macrophages and the immune system during HIV and SARS-CoV-2 infection, Session 2 will focus on challenges to study HIV/SIV reservoirs, and Session 3 will really have the highlights from recent awardees of the NIMH/NINDS/NIDA Myeloid Reservoir RFA. (nih.gov)
- We previously reported that granulocyte macrophage colony-stimulating factor (GM-CSF) upregulates PAR 2 expression by human macrophages [ 2 ]. (scientificarchives.com)
Neutrophils8
- Its exact role in the function of the neutrophil is unknown, but, in human neutrophils, proteinase 3 contributes to the proteolytic generation of antimicrobial peptides. (wikipedia.org)
- Recombinant human GM-CSF (rhGM-CSF) promotes the production of myeloid cells of the granulocytic (neutrophils, eosinophils and basophils) and monocytic lineages in vivo. (stemcell.com)
- CCL8 has chemotactic fuction for monocytes, eosinophils and neutrophils. (watson-bio.cn)
- Note: Certain human cell lines or cell types (e.g., neutrophils, monocytes) can first be treated with reagents that block receptors for the Fc regions of immunoglobulin to avoid nonspecific immunofluorescent staining mediated by Fc receptors. (bdbiosciences.com)
- Cytokine that is chemotactic for monocytes but not for neutrophils. (enquirebio.com)
- The second processed form RANTES(4-68) exhibits reduced chemotactic and HIV-suppressive activity compared with RANTES(1-68) and RANTES(3-68) and is generated by an unidentified enzyme associated with monocytes and neutrophils. (cusabio.com)
- Neutrophils release serine proteases such as neutrophil elastase, proteinase 3, cathepsin G. These proteolytic enzymes activate protease-activated receptors (PARs) to induce intracellular signaling. (scientificarchives.com)
- The proinflammatory effects of lipopolysaccharide (LPS) are amplified during pre-existing neutrophilic inflammation, as neutrophils augment LPS-mediated proinflammatory signaling [ 3 ]. (scientificarchives.com)
Eosinophils3
- On eosinophils, MCP-4 has similar efficacy and potency as MCP-3, RANTES, and cotaxin. (rupress.org)
- Chemoattractant for blood monocytes, memory T-helper cells and eosinophils. (cusabio.com)
- IL-16 is a CD8+ T cell-derived cytokine that induces chemotaxis of CD4+ T cells and CD4+ monocytes and eosinophils. (thomassci.com)
Cytokine7
- Dust-induced inflammatory cytokine secretion in human monocytes and bronchial epithelial cells was evaluated. (cdc.gov)
- To date, three broad approaches to adjunctive (non-antibiotic) therapy have been considered for the treatment of sepsis: (1) optimizing oxygen delivery through oxygenation/ventilation strategies and fluid/vasopressor use to maintain peripheral perfusion, (2) reducing bacterial virulence factors via anti-endotoxin antibodies and endotoxin removal columns and (3) targeting host response factors using corticosteroids, anti-cytokine drugs, and anticoagulants. (nature.com)
- Human 27-plex cytokine panel (Bio-plex Pro Human 27-plex cytokine panel, Bio-Rad, CA, USA). (cdc.gov)
- Cytokine concentrations were calculated from standard curves of known concentrations of recombinant human cytokines. (cdc.gov)
- Proleukin (aldesleukin) for injection is a recombinant version of interleukin-2 (IL-2), an endogenous cytokine that has multiple effects on immune response. (proleukin.com)
- In this study, we investigated the immunomodulatory effect of the hematopoietic progenitor activator cytokine, Fms-like tyrosine kinase 3-ligand (FL) when co-administered with the rVCG-Pmp18.1 vaccine as a strategy to enhance the protective efficacy and the potential mechanism of immunomodulation. (cdc.gov)
- Pathophysiologically, asthma exert different effects at different concentrations, can is characterized by constriction of airway smooth synergize or antagonize the effects of other cytokines muscle, hyper secretion of mucus, edema and airway and regulated in a complex manner and function via hyper responsiveness (AHR),[3] mucus secretion and cytokine cascade. (cdc.gov)
Binds3
- On these cells, it binds to receptors that recognize MCP-1, MCP-3, and RANTES. (rupress.org)
- When Recombinant Human BTLA (Catalog # 9235-BT ) is immobilized at 1.00 µg/mL (100 µL/well), Biotinylated Recombinant Human HVEM/TNFRSF14 Fc Chimera Avi-tag binds with an ED 50 of 30.0-180 ng/mL. (rndsystems.com)
- When Recombinant Human BTLA ( 9235-BT ) is immobilized at 1.00 µg/mL (100 µL/well), Biotinylated Recombinant Human HVEM/TNFRSF14 Fc Chimera Avi-tag binds with an ED 50 of 30.0-180 ng/mL. (rndsystems.com)
Chemokine2
- A novel human CC chemokine complementary DNA was identified in a library constructed from human fetal RNA, cloned into a baculovirus vector, and expressed in Sf9 insect cells. (rupress.org)
- IL-28A induces ELR(-) CXC chemokine mRNA in human peripheral blood mononuclear cells, in an IFN-gamma-independent manner. (prospecbio.com)
Cytokines3
- In synergy with other cytokines such as stem cell factor, IL-3, erythropoietin, and thrombopoietin, it also stimulates erythroid and megakaryocyte progenitor cells (Barreda et al. (stemcell.com)
- 2008). Inflammation, T-cell phenotype, and inflammatory cytokines in chronic kidney disease patients under hemodialysis and its relationship to resistance to recombinant human erythropoietin therapy . (up.pt)
- These growth factors induce monocyte activation, migration, and production of inflammatory cytokines and VEGF. (cellgs.com)
Reactivity1
- Human and murine IL-16 show significant cross-species reactivity. (thomassci.com)
Induces1
- IL-3 also induces histamine release from mature mast cells during proliferation and activation. (fujifilm.com)
Cells13
- The aim of this study was to determine the distribution of microbial endotoxin, 3-hydroxy fatty acids (3-OHFA), muramic acid, and ergosterol and evaluate inflammatory responses in human monocytes and bronchial epithelial cells with various dust samples. (cdc.gov)
- A) The biological activity of Human Recombinant GM-CSF was tested by its ability to promote the proliferation of TF-1 cells. (stemcell.com)
- These three MCPs were found by IL-1-beta triggered human MG-63 osteosarcoma cells. (watson-bio.cn)
- Whole blood was treated with Pharm Lyse™(Cat No. 555899) to lyse erythrocytes, then blocked with 5 ug/10^6 cells normal polyclonal human IgG (Sigma No. I-4506) prior to staining with either 0.5ug/10^6 cells PE Mouse Anti-Human CD116 (Cat. (bdbiosciences.com)
- IL-3 is produced primarily by activated T cells but can also be synthesized by mast cells, thymic epithelial cells and neurons. (fujifilm.com)
- Measured by its ability to inhibit IL-22-induced IL-10 secretion by COLO 205 human colorectal adenocarcinoma cells. (rndsystems.com)
- We found that bronchoalveolar lavage fluid (BALF) from 11 patients with idiopathic pulmonary alveolar proteinosis (IPAP) suppressed the growth of peripheral blood monocytes and TF-1 cells, a cell line dependent on either GM-CSF or interleukin-3 (IL-3). (wiley.com)
- The inhibitory effect of PAP-BALF occurred only when TF-1 cells were cultured with GM-CSF but not when cultured with IL-3, suggesting that PAP-BALF contains a factor that specifically interferes with GM-CSF function. (wiley.com)
- Measured in an anti-viral assay using HepG2 human hepatocellular carcinoma cells infected with encephalomyocarditis (EMC) virus. (creativebiomart.net)
- The results demonstrated that the recombinant λ-phages, due to their capabilities in transducing mammalian cells, can also be considered in design and construction of novel and safe phage-based nanomedicines. (biomedcentral.com)
- The recombinant viruses obtained were unstable, although the foreign genes were expressed efficiently in the mammalian cells infected with the viruses. (lookformedical.com)
- Induction of CD8+ cytotoxic T cells is considered one of the important correlates for the protective efficacy of candidate human immunodeficiency virus type 1 (HIV-1) vaccines. (lookformedical.com)
- Clinical trials of LAK cells in humans are ongoing but this approach has not gained widespread use and is generally considered less effective than other cell therapies. (msdmanuals.com)
Secretion4
- Agricultural dusts induced monocyte tumor necrosis factor (TNF) alpha, interleukin (IL)-6, IL-8, and epithelial cell IL-6 and IL-8 secretion. (cdc.gov)
- Monocyte and epithelial IL-6 and IL-8 secretion was not dependent on endotoxin. (cdc.gov)
- House dust(s) induced monocyte TNFalpha, IL-6, and IL-8 secretion. (cdc.gov)
- There are four alternatively spliced PlGF isoforms (PlGF-1, PlGF-2, PlGF-3, and PlGF-4), each with unique secretion patterns and heparin-binding affinities. (cellgs.com)
Interleukin2
- Results of treatment of 255 patients with metastatic renal cell carcinoma who received high-dose recombinant interleukin-2 therapy. (proleukin.com)
- High-dose recombinant interleukin 2 therapy for patients with metastatic melanoma: analysis of 270 patients treated between 1985 and 1993. (proleukin.com)
Lymphocytes2
- Like MCP-3, MCP-4 is a chemoattractant of high efficacy for monocytes and T lymphocytes. (rupress.org)
- Fluorescent histograms were derived from gated events with the side and forward light-scatter characteristics of viable lymphocytes (left panel), monocytes (center panel) and granulocytes (right panel). (bdbiosciences.com)
Epithelial1
- Muramic acid, endotoxin, 3-hydroxy fatty acids, and ergosterol content explain monocyte and epithelial cell inflammatory responses to agricultural dusts. (cdc.gov)
Species4
- IL-22BP blocks the interaction of IL-22 with IL-22 R, preventing IL-22 induced production of reactive oxygen species, IL-6, IL-10, and TNF-a (3-8). (rndsystems.com)
- Phylogenetic evidence shows that HIV-1 and HIV-2 were introduced into humans through independent cross-species transmission of simian immunodeficiency virus (SIV) strains from distinct, naturally infected, nonhuman primate (NHP) hosts. (cdc.gov)
- HIV-1 groups M, N, and O are believed to have arisen as 3 separate cross-species transmissions from chimpanzees, and each of the HIV-2 subtypes A-G was the result of independent transmissions from sooty mangabeys ( Cercocebus atys ) to humans. (cdc.gov)
- Nevertheless, hunting and butchering wild NHPs for food, which expose humans to NHP blood and body fluids, are widespread in sub-Saharan Africa and may lead to ongoing transmission from any of the 33 species of NHP that are known to harbor their own unique SIV strains. (cdc.gov)
Endothelial1
- PlGF-3 is an angiogenic factor, which promotes endothelial cell growth and angiogenesis, being expressed exclusively in the placenta. (cellgs.com)
Assay3
- The samples were tested in a binding assay with recombinant human ACE2-Fc Chimera. (biolegend.com)
- In this work, we have tested the human canonical members of the RNase family using a spot-culture growth inhibition assay based mycobacteria-infected macrophage model for evaluating their anti-tubercular properties. (frontiersin.org)
- Using the reverse haemolytic plaque assay, the aims of this study were to determine if the upregulation of TNF-α could be confirmed and to investigate whether this was monocyte or macrophage specific. (ersjournals.com)
Chemotaxis3
- The biological activity determined by a chemotaxis bioassay using human blood monocytes is in a concentration range of 10-100 ng/ml. (goldbio.com)
- Additionally, the protein's biological activity is demonstrated through a chemotaxis bioassay using human peripheral blood monocytes, with an effective concentration range of 1.0-10 ng/ml. (cusabio.com)
- The processed form RANTES(3-68) acts as a natural chemotaxis inhibitor and is a more potent inhibitor of HIV-1-infection. (cusabio.com)
Neutrophil2
- Characterization of proteinase-3 (PR-3), a neutrophil serine proteinase. (wikipedia.org)
- Ligation of HVEM by LIGHT triggers T cell, monocyte, and neutrophil activation (8, 10) and contributes to Th1 inflammation and cardiac allograft rejection (13, 14). (rndsystems.com)
Reconstitution3
- 3 months, -20 to -70 °C under sterile conditions after reconstitution. (watson-bio.cn)
- Lyophilized IFN-Lambda 2 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution IFN-Lambda 2 Recombinant should be stored at 4°C between 2-7 days and for future use below -18°C. (prospecbio.com)
- 70°C for 3 months under sterile conditions after reconstitution. (creativebiomart.net)
Amino4
- Mature human HVEM consists of a 164 amino acid (aa) extracellular domain (ECD) with three cysteine-rich domains (CRD), a 21 aa transmembrane segment, and a 60 aa cytoplasmic tail with a TRAF interaction domain (2, 3). (rndsystems.com)
- IL-28A human recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 175 amino acids and having a molecular mass of 19.6 kDa. (prospecbio.com)
- Mature mouse IL-22BP consists of two tandem Fibronectin type-III domains and shares 85% and 68% amino acid sequence identity with rat IL-22BP and the short isoform of human IL-22BP, respectively (6, 14). (rndsystems.com)
- It is conserved in mice and humans, with ~88% amino acid identity. (medchemexpress.com)
Antigen2
- Leukocyte immunoglobulin-like receptor subfamily B member 4 (LILRB4) is also known as CD85 antigen-like family member K (CD85K), Immunoglobulin-like transcript 3 (ILT-3), Leukocyte immunoglobulin-like receptor 5 (LIR-5), Monocyte inhibitory receptor HM18, which belongs to the leukocyte immunoglobulin-like receptor (LIR) family. (transcriptionfactor.org)
- A novel CD18 genomic deletion in a patient with severe leucocyte adhesion deficiency: a possible CD2/lymphocyte function-associated antigen-1 functional association in humans. (lu.se)
Antibody2
- See more details about Hi-Affi™ recombinant antibody benefits . (creativebiolabs.net)
- Download resources about recombinant antibody development and antibody engineering to boost your research. (creativebiolabs.net)
Ligand1
- Cellular Basis for the Enhanced Efficacy of the Fms-Like Tyrosine Kinase 3 Ligand (FL) Adjuvanted VCG-Based Chlamydia abortus Vaccine. (cdc.gov)
Catalog2
- 2 μg/lane of Biotinylated Recombinant Human HVEM/TNFRSF14 Fc Chimera Avi-tag (Catalog # AVI10726) was resolved with SDS-PAGE under reducing (R) and non-reducing (NR) conditions and visualized by Coomassie® Blue staining, showing bands at 61-67 kDa and 120-130 kDa, respectively. (rndsystems.com)
- The ED 50 for this effect is 1-4 μg/mL in the presence of 0.5 ng/mL of Recombinant Mouse IL-22 (Catalog # 582-ML ). (rndsystems.com)
Enzyme1
- Proteinase 3, also known as PRTN3, is an enzyme that in humans is encoded by the PRTN3 gene. (wikipedia.org)
Sequence3
- Within the ECD, human HVEM shares 55% aa sequence identity with mouse and rat HVEM. (rndsystems.com)
- A DNA sequence encoding the Human I-309 / CCL1 / TCA-3, was expressed in the hosts and tags indicated. (enquirebio.com)
- The human p28 gene encodes a 243 aa precursor that contains a 28 aa signal sequence and 215 aa mature region. (creativebiomart.net)
Erythropoietin1
- 2008). IL-7 serum levels and lymphopenia in hemodialysis patients, non-responders to recombinant human erythropoietin therapy . (up.pt)
CCL71
- MCP-2 has two homogeneous MCP-1 (CCL2) and MCP-3 (CCL7). (watson-bio.cn)
Vaccine5
- We also characterized the therapeutic anti-tumor effects of the recombinant λ-HPV-16 E7 phage in C57BL/6 tumor mice model as a cancer vaccine. (biomedcentral.com)
- Human HPV-16 E7 was also chosen for vaccine development because HPVs, particularly HPV-16, are associated with most cervical cancers. (biomedcentral.com)
- A canarypox vaccine expressing multiple human immunodeficiency virus type 1 genes given alone or with rgp120 elicits broad and durable CD8+ cytotoxic T lymphocyte responses in seronegative volunteers. (lookformedical.com)
- Radical control of malaria likely requires a vaccine that targets both the asymptomatic liver stages and the disease-causing blood stages of the human malaria parasite Plasmodium falciparum . (nature.com)
- However, the development of an efficacious malaria vaccine has turned out to be complicated, partly because of the complex life cycle of the parasite and a long history of co-evolutionary adaptation with the human host. (nature.com)
Immunodeficiency virus2
- Furthermore, TB prognosis is significantly aggravated during human immunodeficiency virus (HIV) co-infection. (frontiersin.org)
- The increased frequency of atypical mycobacterial infection stems from advances in the diagnostic procedures concerning the infection paired with the prevalence of mycobacterial disease in immunocompromised patients infected with the human immunodeficiency virus (HIV). (medscape.com)
Concentration range1
- Determined by its ability to chemoattract human monocytes using a concentration range of 0.1-100.0 ng/ml. (peprotech.com)
Cell4
- THP-1 differentiated with TPA overnight, then treated with LPS for 7 hours with addition of BFA for the last 3 hours, whole cell lysate. (abcam.com)
- For this purpose, recombinant lambda phages were characterized to compare their performance for gene delivery and expression in four cell lines from different sources. (biomedcentral.com)
- Immunoplates for Exosome capture and quantification from human biofluids (plasma, serum, urine, saliva) and from human or mouse cell media. (transcriptionfactor.org)
- CAR T cell immunotherapy for human cancer. (msdmanuals.com)
Infect1
- LacZ recombinant FWPV (rFWPV) was found subsequently to infect human DCs that had been cultured ex vivo from peripheral blood monocytes. (lookformedical.com)
Endotoxin2
Functional1
- It has marked functional similarities to MCP-3 and eotaxin. (rupress.org)
Inflammatory1
- It has shown excellent anti-inflammatory and immunomodulatory effects in the treatment of various human inflammatory disorders in animal models. (bvsalud.org)
Antimicrobial2
- In addition to its direct antimicrobial activities, BD-4 is chemoattractant towards human blood monocytes. (peprotech.com)
- Overall, our data anticipate a biological role for human antimicrobial RNases in host response to mycobacterial infections and set the basis for the design of novel anti-tubercular drugs. (frontiersin.org)
Blood4
- Flow cytometric analysis of GM-CSFRα expression on human peripheral blood leucocytes. (bdbiosciences.com)
- Blood 2004(3): 1105-13 [ PubMed abstract ]. (lu.se)
- Since ongoing lentivirus emergence would be of substantial importance to global public health, we looked for evidence of SIV in a unique collection of plasma from persons with known levels of exposure to the blood and body fluids of NHPs ( 3 ). (cdc.gov)
- and 3) persons from a general population (n = 1,071) from urban and rural areas in Cameroon where people may handle NHP meat but are unlikely to have repeated contact with the blood or body fluids of freshly killed animals. (cdc.gov)
Gene4
- 2012). Glucocerebrosidase gene variants in parkinsonian patients with Machado Joseph/spinocerebellar ataxia 3 . (up.pt)
- It is composed of EBI3 (EBV-induced gene 3), a 34 kDa glycoprotein that is related to the p40 subunit of IL-12 and IL-23, and p28, the 28 kDa glycoprotein that is related to the p35 chain of IL-12). (creativebiomart.net)
- We then inserted the genes encoding lacZ, luciferase (luci), and envelope of human T-lymphotropic virus type 1 (HTLV-1 env) into the TK gene of CaPV to evaluate its suitability as an expression vector. (lookformedical.com)
- Replication-competent recombinant VV (rVV) was also shown to be capable of transferring the marker gene to primary DC cultures. (lookformedical.com)
Receptors1
- CD116) and the common subunit βc (CD131) shared with IL-3 and IL-5 receptors (Broughton et al. (stemcell.com)