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Chemokine CCL7Monocyte Chemoattractant ProteinsChemokine CCL2Chemokine CCL8Chemotactic FactorsSpiral LaminaChemokinesReceptors, CCR2CytokinesChemokine CCL5Interleukin-8Chemotaxis, LeukocyteReceptors, ChemokineMacrophage Inflammatory ProteinsCells, CulturedChemokine CCL4RNA, MessengerChemokine CCL3Campylobacter rectusChemokine CCL11MacrophagesMonocytesInflammationMonokinesChemokines, CXCChemokines, CCInterleukin-6Inflammation MediatorsReceptors, CCR3Mice, Inbred C57BLChemotaxisChemokine CXCL10Tumor Necrosis Factor-alphaReceptors, CytokineChemokine CXCL6LipopolysaccharidesEnzyme-Linked Immunosorbent AssayEikenella corrodensInterleukin-1Disease Models, AnimalGene ExpressionIntercellular Adhesion Molecule-1Up-RegulationReverse Transcriptase Polymerase Chain ReactionLeukocytesPrevotella intermediaVeillonellaCell MovementEosinophilsGene Expression RegulationLungNF-kappa BEndothelium, VascularRecombinant ProteinsChemokine CXCL5Cell LineTreponema denticolaMolecular Sequence DataAggressive PeriodontitisBiological MarkersMice, Inbred BALB CEpithelial CellsFusobacterium nucleatumInterferon-gammaDose-Response Relationship, DrugBlotting, WesternImmunohistochemistryPeriodontal Attachment Lossbeta-ThromboglobulinPeriodontal PocketNeutrophilsChronic PeriodontitisAntigens, CD14Chemokine CXCL1Monocytes, Activated KillerActinomycesChemokine CXCL2Aggregatibacter actinomycetemcomitansGingivaAmino Acid SequenceSignal TransductionReceptors, IgGPhagocytosisCell AdhesionIntercellular Signaling Peptides and ProteinsFlow CytometryMice, KnockoutBase SequenceFibroblastsPolymerase Chain ReactionLeukocytes, MononuclearAntigens, CDCell DifferentiationAntigens, Differentiation, MyelomonocyticMacrophage ActivationMacrophage Colony-Stimulating FactorDendritic CellsU937 CellsInterleukin-10Granulocyte-Macrophage Colony-Stimulating Factor
CytokineChemoattractantEosinophilsRecombinantLymphocytesMCP1CytokinesSecretionMacrophagesBone marrowFactorCCL8NeutrophilsAntibodiesEndothelial cellsMitogen-activaTumorEotaxinSerumChemokinesSeven-transmembrane receptorsProliferationInflammatoryELISAIntercellularCellularConcentrationsHumanCCL7GenesPermeabilityMRNAAminoHighVascularFunctionSignal
Cytokine4
  • Chemokine (C-C motif) ligand 7 (CCL7) is a small cytokine that was previously called monocyte-chemotactic protein 3 (MCP3). (wikipedia.org)
  • The small chemotactic cytokine CCL4 (MIP-1 beta) is a chemoattractant for natural killer cells, monocytes and a variety of other immune cells. (immunochemistry.com)
  • Chemokine ligand 4 (CCL4) is a small chemotactic cytokine belonging to the CC chemokine family that is also known as macrophage inflammatory protein-1β (MIP-1 beta). (immunochemistry.com)
  • No differences were found in interstitial cytokine or total protein concentrations between arms in control subjects. (nih.gov)
Chemoattractant4
Eosinophils1
Recombinant4
  • The mature recombinant protein that was released had the NH2-terminal sequence pyro-QPDALNVPSTC. (rupress.org)
  • Matrices listed below were spiked with certain level of recombinant Monocyte Chemotactic Protein 1 (MCP1) and the recovery rates were calculated by comparing the measured value to the expected amount of Monocyte Chemotactic Protein 1 (MCP1) in samples. (uscnk.com)
  • Recombinant Human CCL7 protein( Gln 24 - Leu 99), fused with His tag, was expressed in HEK293. (creativebiomart.net)
  • Human CCL4 Recombinant Protein is purified chemokine ligand 4 (CCL4, MIP-1 beta) produced in yeast. (immunochemistry.com)
Lymphocytes1
  • Human MCP-1, MCP-2 and MCP-3 all have chemotactic activity for a variety of cell types, including T lymphocytes and monocytes (Van Coillie et al. (justia.com)
MCP113
  • This assay has high sensitivity and excellent specificity for detection of Monocyte Chemotactic Protein 1 (MCP1). (uscnk.com)
  • No significant cross-reactivity or interference between Monocyte Chemotactic Protein 1 (MCP1) and analogues was observed. (uscnk.com)
  • Intra-assay Precision (Precision within an assay): 3 samples with low, middle and high level Monocyte Chemotactic Protein 1 (MCP1) were tested 20 times on one plate, respectively. (uscnk.com)
  • Inter-assay Precision (Precision between assays): 3 samples with low, middle and high level Monocyte Chemotactic Protein 1 (MCP1) were tested on 3 different plates, 8 replicates in each plate. (uscnk.com)
  • The linearity of the kit was assayed by testing samples spiked with appropriate concentration of Monocyte Chemotactic Protein 1 (MCP1) and their serial dilutions. (uscnk.com)
  • The microtiter plate provided in this kit has been pre-coated with an antibody specific to Monocyte Chemotactic Protein 1 (MCP1). (uscnk.com)
  • Standards or samples are then added to the appropriate microtiter plate wells with a biotin-conjugated antibody specific to Monocyte Chemotactic Protein 1 (MCP1). (uscnk.com)
  • After TMB substrate solution is added, only those wells that contain Monocyte Chemotactic Protein 1 (MCP1), biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. (uscnk.com)
  • Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Monocyte Chemotactic Protein 1 (MCP1) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids. (scalegen.com)
  • Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Human Monocyte Chemotactic Protein 1 (MCP1) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids with no significant corss-reactivity with analogues from other species. (scalegen.com)
  • Description: A sandwich quantitative ELISA assay kit for detection of Rat Monocyte Chemotactic Protein 1 (MCP1) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids. (scalegen.com)
  • Description: Quantitativesandwich ELISA kit for measuring Pig monocyte chemotactic protein 1, MCP1 in samples from serum, plasma. (scalegen.com)
  • CCL7 is a small protein that belongs to the CC chemokine family and is most closely related to CCL2 (previously called MCP1). (wikipedia.org)
Cytokines3
  • Chemokines," which take their name from chemotactic cytokines, are small secreted polypeptides that regulate movement of immune cells into tissues (Baggiolini et al. (justia.com)
  • Concentrations of 17 selected cytokines, VEGF-C, and total protein were measured in blister fluid and in plasma. (nih.gov)
  • Previously, we have shown in a mouse model that exposure to hog dust extract (HDE) collected from a CAFO results in the activation of protein kinase C (PKC), elevated lavage fluid cytokines/chemokines including interleukin-6 (IL-6), and the development of significant lung pathology. (cdc.gov)
Secretion1
  • Regulation of Monocyte Chemotactic Protein - 1 secretion by the Two-Pore-Domain Potassium (K2P) channel TREK- 1 in human alveolar epithelial cells. (mcp-1.com)
Macrophages1
  • Atherosclerosis starts with dysfunctional changes in the endothelium induced by disturbed shear stress which can lead to endothelial and platelet activation, adhesion of monocytes on the activated endothelium, and differentiation into proinflammatory macrophages, which increase the uptake of oxidized LDL (oxLDL) and turn into foam cells, exacerbating the inflammatory signalling. (hindawi.com)
Bone marrow2
  • The positive effect of CCL7 is mainly observed in monocyte mobilization from bone marrow to blood circulation and in the recruitment of monocytes to sites of inflammation. (wikipedia.org)
  • Monocytes (MC) are bone marrow (BM) derived mononuclear phagocytes that play an important role in innate immune response and are the major immune cell population in chronic tissue inflammatory ( 1 , 2 ). (frontiersin.org)
Factor2
CCL81
  • Human CCL8, also known as monocyte chemotactic protein 2 (MCP-2), is belonging to the CC chemokine family. (watson-int.cn)
Neutrophils1
Antibodies2
  • The invention provides antibodies that bind to a plurality of β-chemokines, particularly monocyte chemotactic proteins MCP-1, MCP-2 and MCP-3. (justia.com)
  • 135 antibodies against 65 mainly immunoregulatory proteins, we of a multitude of different genes (8, 9). (lu.se)
Endothelial cells3
  • LFA-1 participates in several processes, such as T cell-mediated killing, T helper and B lymphocyte responses, natural killing, Ab-dependent cellular cytotoxicity by monocytes and granulocytes, and adherence of leukocytes to endothelial cells, fibroblasts, and epithelial cells. (sigmaaldrich.com)
  • Visfatin Stimulates Production of Monocyte Chemotactic Protein-1 and Interleukin-6 in Human Vein Umbilical Endothelial Cells. (thieme-connect.com)
  • The vascular endothelium is formed by a sheet of endothelial cells tethered together by junctional proteins such as tight and adherens junctions. (bvsalud.org)
Mitogen-activa1
  • The anti-inflammatory effects of SHE treatment involved blocking of the mitogen-activated protein kinase and signal transducer and activator of transcription 1 signaling pathways. (researchgate.net)
Tumor2
  • In this respect, in contrast to predictors based for each serum protein was determined by comparing the samples upon tumor characteristics at the time of surgery, serum is a par- collected at the primary operation and then 3-6 mo later. (lu.se)
  • Adipocyte-derived factors involved in tumor progression include proteins such as adiponectin, leptin, TNF-α, monocyte chemotactic protein-1 (MCP-1), IL-6, and ECM components that control tumor cell behavior within the tumor microenvironment. (jci.org)
Eotaxin2
  • Monocyte chemotactic protein 4 (MCP-4), a novel structural and functional analogue of MCP-3 and eotaxin. (rupress.org)
  • MCP-4 shares the pyroglutamic acidproline NH2-terminal motif and 56-61% sequence identity with the three known monocyte chemotactic proteins and is 60% identical to eotaxin. (rupress.org)
Serum4
  • Description: A sandwich ELISA kit for detection of Monocyte Chemotactic Protein 1 from Human in samples from blood, serum, plasma, cell culture fluid and other biological fluids. (scalegen.com)
  • This risk assessment was not dependent on the type of adju- decoding patterns of immunoregulatory serum proteins could re- vant therapy received by the patients. (lu.se)
  • Conse- demonstrated that this protein signature provided an added value quently, using minute amounts of nonfractionated serum (14) and compared with conventional clinical parameters. (lu.se)
  • C reactive protein (CRP), an important serum marker of atherosclerotic vascular disease, has recently been reported to be active inside human atherosclerotic plaques. (bmj.com)
Chemokines1
Seven-transmembrane receptors1
  • These receptors belongs to the G protein-coupled seven-transmembrane receptors. (wikipedia.org)
Proliferation2
  • The in vitro effects of MSC-Exo on immune cell migration and responder T cell proliferation were examined by chemotactic assays and lymphocyte proliferation assays, respectively. (nature.com)
  • The proliferation of cardiac fibroblasts (CFs) and excessive extracellular matrix protein accumulation are the basic pathological processes of myocardial fibrosis. (thieme-connect.com)
Inflammatory4
  • The protein intercellular adhesion molecule 3 (ICAM-3) functions as a receptor for LFA-1 (leukocyte function-associated antigen-1) and mediates adhesive interactions of leukocyte cell surface adhesion molecules in inflammatory and immune response. (sigmaaldrich.com)
  • The expressions of inflammatory factors and NF‑κB pathway proteins were detected by immunofluorescence, ELISA, western blotting and RT‑qPCR. (spandidos-publications.com)
  • Mechanistically, DIS not only decreased the expressions of inflammatory factors including IL‑1β, NOD‑like receptor thermal protein domain associated protein 3, monocyte chemotactic protein 1, IL‑6, TNF‑α and IL‑18 but also reduced the level of phosphorylation of NF‑κB p65 in vivo and in vitro , which was similar to the impact of Bay11‑7082. (spandidos-publications.com)
  • 3 Moreover, inflammatory markers, such as C reactive protein (CRP), are strong independent predictors of future cardiovascular risk. (bmj.com)
ELISA1
  • The Human CCL4/MIP-1 beta protein can be used in cell culture, as a CCL4/MIP-1 beta ELISA Standard, and as a Western Blot Control. (immunochemistry.com)
Intercellular1
  • Exosomes are 40-100 nm soluble microvesicles with a bi-lipid membrane and a cargo abundant in proteins and RNAs, which are now believed to be important for intercellular communication 9 . (nature.com)
Cellular2
  • Feasibility of electrospun polydioxanone monocyte chemotactic protein-1 (MCP-1) hybrid scaffolds as potential cellular homing devices. (southernbiotech.com)
  • Other recent studies, including one conducted at the Joslin Diabetes Center, have found another member of the sirtuin family of cellular proteins that may play a major role in how fat is produced and stored, offering a new target for treatments to prevent obesity and reduce the risk of type 2 diabetes. (lifeextension.com)
Concentrations2
  • Studies showed that monocyte chemotactic protein-1 (MCP-1) concentrations are increased in obesity. (johnshopkins.edu)
  • In BCRL subjects, monocyte chemotactic protein 1 (MCP-1) (P = 0.009) and total protein (P = 0.035) concentrations were higher in blister fluid from edematous arms compared with nonedematous arms. (nih.gov)
Human2
  • The biological activity determined by a chemotaxis bioassay using human peripheral blood monocytes is in a concentration range of 10-100 ng/ml. (watson-int.cn)
  • Cannabinoid type-2 (CB 2 ) receptor activation was shown to reduce the production of the monocyte chemotactic protein-2 (MCP-2) chemokine in polyinosinic-polycytidylic acid [poly-(I:C)]-stimulated human keratinocyte (HaCaT) cells, an in vitro model of allergic contact dermatitis (ACD). (aspetjournals.org)
CCL71
  • For example, CCL7-mediated stimulation of CCR2 chemokine receptors on monocytes is participating in the elimination of Listeria monocytogenes infections by the recruitment of monocytes and TNF/iNOS-producing dendritic cells (TipDCs). (wikipedia.org)
Genes1
  • Importantly, high-fat feeding strongly increased intestinal permeability and reduced the expression of genes coding for proteins of the tight junctions. (diabetesjournals.org)
Permeability1
  • Interstitially increased MCP-1 levels may augment local microvascular protein permeability in BCRL. (nih.gov)
MRNA3
  • mRNA expression levels of CXCL9, a chemokine recruiting CD8 + T cells, were lower in dLNs of STZ-mice than in normoglycemic mice after PD-1-Ab treatment, and its protein was expressed in DCs. (nature.com)
  • RT-PCR and Western blot analysis were used for determining procollagen I and III mRNA expression and protein production. (thieme-connect.com)
  • It was also found that visfatin upregulated collagen I and III production, procollagen I and III mRNA expression and protein production. (thieme-connect.com)
Amino2
  • The second exon encodes amino acids 3-42 of the mature proteins. (wikipedia.org)
  • The mature protein about 76 amino acids is secreted after cleavage of the signal peptide. (wikipedia.org)
High2
  • The encoded protein is extensively glycosylated and contains five Ig-like domains that share high homology with corresponding domains in ICAM-1 and ICAM-2. (sigmaaldrich.com)
  • Murine monocytes (MC) are classified into Ly6C high and Ly6C low MC. (frontiersin.org)
Vascular1
  • Normally, activation of the CB 1 receptor regulates renal vascular hemodynamics and stimulates the transport of ions and proteins in different nephron compartments. (degruyter.com)
Function1
  • Resveratrol activated a protein in the sirtuin family (SIRT1), which then stimulated the activity of another protein involved in mitochondrial function. (lifeextension.com)
Signal1
  • The third exon is composed of the C-terminal region of the protein, a 3′-UTR containing one or more destabilizing AU-rich sequences and a polyadenylation signal. (wikipedia.org)