Goldman-Rakic P, Brown R Postnatal development of monoamine content and synthesis in the cerebral cortex of rhesus monkeys. (unipa.it)
The study, published online in Nature Communications , followed four infant rhesus monkeys for one year after Zika virus infection at one month of age. (emoryhealthsciblog.com)
Studying a rhesus monkey until the age of 1 translates to the equivalent of 4 to 5 years in human age. (emoryhealthsciblog.com)
Mason writes an interesting review in the New York Times 10/31/06 science section focusing on experiments at the University of Wisconsin Primate research center which have closely monitored rhesus monkeys on restricted and normal-calorie diets. (dericbownds.net)
At 28, getting on for a rhesus monkey, Matthias is losing his hair, lugging a paunch and getting a face full of wrinkles. (dericbownds.net)
Effect of repeated abstinence on chronic ethanol self-administration in the rhesus monkey. (ohsu.edu)
Hippocampus1
Life stress also differentially affected, as a function of serotonin transporter genotype, functional connectivity of the amygdala and hippocampus with a wide network of other regions, as well as gray matter structural features, and affected individuals' level of rumination. (dericbownds.net)
Prefrontal cortex2
The amygdala is connected with the prefrontal cortex, an area involved with our highest intellectual properties, and receives sensory inputs from it all the time. (typepad.com)
6. Björklund, A., Divac, I., Lindvall, O.: Regional distribution of catecholamines in monkey cerebral cortex, evidence for a dopaminergic innervation of the primate prefrontal cortex. (lu.se)
Macaque1
Amygdala growth from youth to adulthood in the macaque monkey. (nprcresearch.org)
Cortical1
Here, we use RNA sequencing, cell imaging, and lineage tracing of mouse and human in vitro NSCs and monkey brain sections to model the generation of cortical neuronal fates. (edu.au)
Functional connectivity1
Developmental sex differences in resting state functional connectivity of amygdala sub-regions. (ohsu.edu)
Mice4
METHODS: Using a pharmacological approach, we examined, in vitro , the role of 5-HT signalling in the regulation of duodenal contractility in neonatal mice (2 days old) compared to the adults. (unipa.it)
RESULTS: 5-HT induced in both duodenal preparations a concentration-dependent muscular contraction, being its efficacy greater in duodenum from neonatal mice. (unipa.it)
In duodenum from neonatal mice pretreatment with atropine, muscarinic receptor antagonist, abolished neurally evoked serotoninergic contraction. (unipa.it)
PFHxS is persistent and poorly metabolized with estimated half-lives of 1 month, 4 months, and 7.3 years in mice, monkeys, and humans, respectively [6,7]. (researchsquare.com)
Cerebral1
Effects of chronic intranasal oxytocin on behavior and cerebral glucose uptake injuvenile titi monkeys. (nprcresearch.org)
Humans1
His earliest work was with cats, but he later did experiments with monkeys and humans, including psychiatric patients. (cognitive-liberty.online)
Proteins1
SNARE Complex-Associated Proteins in the Lateral Amygdala of Macaca mulatta Following Long-Term Ethanol Drinking. (ohsu.edu)
Sides1
And while there are two units (left and right sides of the brain) to the amygdala, it is more often discussed as if it were one organ, so the singular term "amygdala", and the common usage plural "amygdalas," not the Latin plural "amygdalae" is used here and throughout most of the medical literature. (typepad.com)
Responses1
As an alternative to permanent lesions, scientists at Yerkes National Primate Research Center sought to test whether chemogenetic techniques could be applied to produce a transient inhibition of the amygdala, well known for regulating emotional responses, in infant non-human primates. (emoryhealthsciblog.com)
Areas2
Kisspeptin, also known as metastin, serves as a gatekeeper of puberty and is mainly expressed in the hypothalamus of rodents, especially the arcuate nucleus (ARC) and the anterioventral periventricular nucleus (AVPV) areas [12], in addition to the paraventricular nucleus and amygdala [13]. (researchsquare.com)
As part of the limbic system , it has connections to other limbic structures including the amygdala and septum , and is also connected with areas of the autonomous nervous system . (cloudfront.net)
Brain4
The amygdala comprises two almond-sized-and-shaped portions of the mid-brain, that are becoming more and more common targets for study. (typepad.com)
But the amygdale is not a part of the conscious brain. (typepad.com)
The study of the function of the amygdale has helped resolve one of the great debates in neuroscience over the last 250 years: Whether the Body (in this case, the amygdala and the brain) governed the Mind (in this case, the sense of consciousness, self-awareness, thought processing, learning and memory), or whether these were two truly distinct operations. (typepad.com)
The amygdala may very well do this by helping the brain identify salient points of new inputs (whether they have red or green flags indicating either danger or reward) and to prioritize them by the use of the "magnitude dial" of the amygdale (important enough to pay close attention, or not so important or threatening and therefore, something to ignore). (typepad.com)
Year1
The numbers of research reports involving the amygdala has been skyrocketing with each passing year. (typepad.com)
Activation1
Based on functional MRI and perfusion data, They found support for a model in which life stress interacts with the effect of serotonin transporter genotype on amygdala and hippocampal resting activation, two regions involved in depression and stress. (dericbownds.net)
Research1
In a laboratory at the Wisconsin National Primate Research Center, Matthias, the monkey on the right, is learning about time's caprice the hard way. (dericbownds.net)
World1
Non-invasive Eye Tracking Methods for New World and Old World Monkeys. (nprcresearch.org)
Major2
As of the date of this blog, September 9, 2009, PubMed reports 21,633 papers in which the amygdala is mentioned, 1933 of them being major review articles. (typepad.com)
Cross-section of the monkey hypothalamus displays two of the major hypothalamic nuclei on either side of the fluid-filled third ventricle. (cloudfront.net)
Lesions3
Experimental neonatal brain lesions in monkeys indicated that the orbital frontal cortex, but not the amygdala, may play a critical role in the quality of infant/mother relationships, and that dysfunction of this structure may result in pervasive impairments of social interactions and reciprocal relationships later in life as found in autism. (nih.gov)
The DREADD-induced behaviors were reminiscent of, but not identical to, those seen after permanent amygdala lesions in infant monkeys, such that neonatal lesions produce a more extensive array of behavioral changes in response to the human intruder task that were not seen with DREADD-evoked inhibition of this region. (eneuro.org)
Their functional role is unknown but we have previously shown that neonatal and adult hippocampal lesions increase their differentiation in the monkey amygdala. (bvsalud.org)
Hippocampus7
Two fronto-limbic brain circuits are developmentally dysfunctional in autism (orbitofrontal-amygdala circuit and dorsolateral prefrontal-hippocampus circuit). (nih.gov)
Social emotional and social cognitive skills in autism have distinct and predictable relationships to the orbitofrontal-amygdala circuit and dorsolateral prefrontal-hippocampus circuits. (nih.gov)
While alterations in excitatory synapse function and plasticity are well-established in Fmr1 knockout (KO) mouse models of FXS, a number of recent electrophysiological and molecular studies now identify prominent defects in inhibitory GABAergic transmission in behaviorally relevant forebrain regions such as the amygdala, cortex, and hippocampus. (karger.com)
1999], consistent with circuit dysfunction and imbalances in excitatory and inhibitory transmission in various brain regions, including the amygdala, cortex, and hippocampus. (karger.com)
2 Stress-induced responses of the HPA system involve afferent inputs from numerous other brain regions including noradrenergic innervation from the brainstem A1 and A2 cell groups and the pontine locus coeruleus, 3 the amygdala, 4 , 5 cerebral cortex and hippocampus. (jpn.ca)
6 In general, the septum and hippocampus have inhibitory actions on HPA activity, whereas the effect of the amygdala is largely permissive. (jpn.ca)
Glucocorticoid hormones terminate the stress response by negative feedback action at the level of the pituitary, hypothalamus and limbic brain areas, including the hippocampus, amygdala and septum. (jpn.ca)
Early postnatal1
Manipulation of neuronal activity during the early postnatal period in monkeys has been largely limited to permanent lesion studies, which can be impacted by developmental plasticity leading to reorganization and compensation from other brain structures that can interfere with the interpretations of results. (eneuro.org)
Dysfunction1
To date, developmental neuroscience studies have relied on permanent lesion techniques to investigate how atypical amygdala development impacts socioemotional behaviors, which may not adequately recapitulate the role of amygdala dysfunction in the manifestation of aberrant behavior. (eneuro.org)
Reactivity1
The current study examined the link between temperamental reactivity in infancy and amygdala development in middle childhood. (nih.gov)
Infant4
We demonstrate that inhibitory DREADDs in the amygdala can be used to manipulate socioemotional behavior in infant monkeys. (eneuro.org)
The current study provides a proof of principle that DREADDs can be used in young infant monkeys to transiently and reversibly manipulate behavior. (eneuro.org)
The present study sought to demonstrate that chemogenetic techniques based on designer receptors exclusively activated by designer drugs (DREADDs) could be used to transiently inhibit amygdala activity in infant monkeys, resulting in alterations in socioemotional behavior. (eneuro.org)
Burbacher TM, Shen DD, Liberato N, Grant KS, Cernichiari E, Clarkson T. Comparison of blood and brain mercury levels in infant monkeys exposed to methylmercury or vaccines containing thimerosal. (autismresearchinstitute.com)
Developmental1
Recently, interest in biological psychiatry has focused on similar brain, social, and emotional developmental processes in monkeys. (nature.com)
Childhood3
We determined the current childhood neurologic status and IQ in 26 subjects who had measurements of CBF performed with PET in the neonatal period between 1983 and 1989 as part of a study of hypoxic- ischemic encephalopathy. (nih.gov)
The mean neonatal CBF in those with abnormal childhood neurologic outcome was significantly higher than in those with normal childhood neurologic outcome (35.64 +/- 11.80 versus 18.26 +/- 8.62 mL 100 g(-1) min(-1), t = 3.36, p = 0.005). (nih.gov)
A significant negative correlation between neonatal CBF and childhood IQ was demonstrated (Spearman rank correlation r = -0.675, p = 0.008). (nih.gov)
Emotional1
The amygdala plays an important role in social behavior and emotional responses to threats in the environment ( Aggleton, 2000 ). (eneuro.org)
Adult1
These models have focused on primates to further the understanding of complex neurocognitive processes due to the similar complexities of the adult human and monkey brains. (nature.com)
Abnormal1
Many neurodevelopmental disorders exhibit abnormal structural or functional amygdala development and altered socioemotional behavior. (eneuro.org)
Exposure1
The primary objective of this scoping review is to identify and characterize the literature relevant to progestogen use during pregnancy and offspring health effects, including prematurity-related neonatal outcomes, congenital malformations, neurological effects, cancer, and other health outcomes related to prenatal exposure. (nih.gov)
Role1
The role of the medial orbital frontal cortex in flexible decision- making in monkeys is related to an inability to use information from bodily states to modify behavioral choices--a deficit that could be related to self-regulation problems observed in autism. (nih.gov)