• pinyin: Huá Huá, born 5 December 2017) are a pair of identical crab-eating macaques (also referred to as cynomolgus monkeys) that were created through somatic cell nuclear transfer (SCNT), the same cloning technique that produced Dolly the sheep in 1996. (wikipedia.org)
  • Wikinews has related news: Healthy cloned monkeys born in Shanghai Since scientists produced the first cloned mammal Dolly the sheep in 1996 using the somatic cell nuclear transfer (SCNT) technique, 23 mammalian species have been successfully cloned, including cattle, cats, dogs, horses and rats. (wikipedia.org)
  • Ever since cloning produced Dolly the sheep , scientists have copied a slew of mammals ranging from dogs to ponies. (engadget.com)
  • Chinese researchers have successfully cloned a macaque monkey fetus twice, producing sister monkeys Hua Hua and Zhong Zhong using the same basic method used to create Dolly. (engadget.com)
  • It took 127 eggs and 79 embryos to get these results, and it still required a fetus to work (Dolly was cloned from an adult). (engadget.com)
  • It became a hot topic in 1996 when Dolly the sheep was cloned via a process called somatic cell nuclear transfer. (archstl.org)
  • The researchers used somatic cell nuclear transfer, the same technique used to clone Dolly the sheep more than two decades ago, to clone the monkey and produce five cloned offspring. (inverse.com)
  • Twenty years have passed since Dolly the sheep was born by cloning (somatic cell nuclear transfer, SCNT) but the results of non-human mammalian cloning are very poor, and cause animal diseases and huge biological losses. (sibi.org)
  • Dolly the sheep was cloned in 1996. (thetablet.org)
  • He stayed on to earn his Ph.D. in molecular biology at Cambridge, training under the legendary geneticist John Gurdon, whose breakthroughs in the 1950s and 1960s were key to the experiments performed by Ian Wilmut, a Gurdon student who cloned Dolly the sheep in 1997. (discovermagazine.com)
  • Even the world's most famous sheep clone, Dolly, who died recently suffered from problems linked to this gene. (irfi.org)
  • It seems that a little knowledge is a dangerous thing, and the authors have allowed themselves to over-interpretate their interesting results,' said Professor Ian Wilmut of the Roslin Institute, in Edinburgh, leader of the team, which cloned Dolly the sheep. (irfi.org)
  • Macaques successfully cloned in China using similar technique which gave birth to Dolly the sheep. (blastingnews.com)
  • Let's wind back the clock: these scientists had already carried out successful human nuclear transfer into an unfertilised egg before Dolly the sheep clone had been made. (globalchange.com)
  • But even they omitted to tell us anything until Dolly was seven months old, well over a year after the cloning technique was successfully carried out and a good two to three years perhaps after they began their secretive work. (globalchange.com)
  • But it was the successful cloning of Dolly the Sheep in 1996 that made waves around the world for she was the first mammal to be created using the procedure. (nyln.org)
  • For the first time, researchers have used the cloning method that produced Dolly the sheep to create two healthy monkeys, bringing science an important step closer to being able to do the same with humans. (queerscifi.com)
  • CNN)For the first time, scientists say they created cloned primates using the same complicated cloning technique that made Dolly the sheep in 1996. (cmaaa.co.za)
  • In the case of Hua Hua and Zhong Zhong, researchers used modern technology developed only in the last couple of years to enhance the technique used to clone Dolly, which is called somatic cell transfer, or SCNT. (cmaaa.co.za)
  • When scientists made Dolly the sheep, years after she was born they used the same cell cluster to make four other sheep clones. (cmaaa.co.za)
  • SHANGHAI (BP) -- The first-ever primates cloned through a technique that produced Dolly the sheep have been cited by Christian bioethicists as a potentially valuable development in animal research. (christian-heritage-news.com)
  • Whereas, cloning à la Dolly means using the DNA information from an adult creature to direct the development through to birth of a genetically identical, though younger, individual. (creation.com)
  • Dolly is not the first reported mammalian clone, but the first one which involved neither forced 'twinning' of an embryo, or implanting an embryonic nucleus. (creation.com)
  • The first cloned monkeys made with somatic cell nuclear transfer (SCNT) were born recently, according to Chinese scientists. (bioedge.org)
  • Although Zhong Zhong and Hua Hua, two genetically identical long-tailed macaques, are not the world's first cloned monkeys, they are the first to be born using SCNT. (bioedge.org)
  • The first successful SCNT monkey clones immediately sparked interest in in the dream of human cloning. (bioedge.org)
  • The original monkey was altered as an embryo by knocking out its BMAL1 gene, which is associated with regulating sleep-wake patterns, and the five newborns produced with SCNT all have identical genomes that also lack the BMAL1 gene. (inverse.com)
  • A) a diagram of the cloning procedure using SCNT, B) the cloned embryos at different stages of development, and C) the five cloned monkeys. (inverse.com)
  • Once the SCNT is done, the cloning is over. (nationalrighttolifenews.org)
  • Most embryos…formed one or two pronuclei at the time of removal from TSA, whereas a slightly higher portion of embryos cleaved…suggesting that some SCNT embryos did not exhibit visible pronuclei at the time of examination… Most cleaved embryos developed to the eight-cell stage…but few progressed to compact morula…and blastocyst. (nationalrighttolifenews.org)
  • Activation of embryonic genes and transcription from the transplanted somatic cell nucleus are required for development of SCNT embryos beyond the eight-cell stage…Therefore, these results are consistent with the premise that our modified SCNT protocol supports reprogramming of human somatic cells to the embryonic state. (nationalrighttolifenews.org)
  • Repeat after me: Human SCNT creates a human embryo through asexual means. (nationalrighttolifenews.org)
  • The cloning is completed when the SCNT is accomplished. (nationalrighttolifenews.org)
  • Again, Saunders is referring to SCNT as "THE" cloning procedure, when there are many other ways to clone a human being as well, and he is scientifically mis-defining the product of SCNT (i.e., the cloned human embryo). (lifeissues.net)
  • I believe that the reprogramming errors are not the only cause of these low rates of cloning: the mammalian SCNT fails with a very high frequency mainly due to the damage that the technique itself inflicts in the egg and the somatic nucleus, and the very few successful cases occur only when the damage is not significant. (sibi.org)
  • True cloning performed by nuclear transfer from an adult and differentiated somatic cell to a previously enucleated egg (somatic cell nuclear transfer, SCNT), gives rise to a new cell, the nuclovulo (nucleus+ovum), distinct from the zygote because the sperm is not involved in its creation, while both can develop as embryos and give rise to offspring. (sibi.org)
  • Zhong Zhong and Hua Hua, born six and eight weeks ago, respectively, at the Chinese Academy of Sciences Institute of Neuroscience in Shanghai, are the first primate clones made by somatic cell nuclear transfer (SCNT). (qz.com)
  • Theoretically, SCNT can produce unlimited clones. (qz.com)
  • The SCNT method involves removing the nucleus from an egg cell and replacing it with another nucleus from differentiated body cells, and the reconstructed egg then develops into a clone of the creature who donated the nucleus. (qz.com)
  • The SCNT technique has worked to create about 20 different animals including frogs, mice, rabbits, pigs, cows and even dogs, but there have been 'numerous attempts to clone non-human primate species, but they all failed,' said Mumming Poo, an author on the paper. (cmaaa.co.za)
  • Researchers from the Chinese Academy of Sciences Institute of Neuroscience announced in a Jan. 24 article for the journal Cell that they produced two genetically-identical long-tailed macaque monkeys using a scientific technique known as somatic cell nuclear transfer (SCNT). (christian-heritage-news.com)
  • citation needed] They are the first cloned primates produced by this technique. (wikipedia.org)
  • This crucial reprogramming step allowed the researchers to overcome the main obstacle that had precluded the successful cloning of primates until now. (wikipedia.org)
  • The birth of the two cloned primates also raised concerns from bioethicists. (wikipedia.org)
  • As Amber Tong reported for Endpoints News at the time, the challenges of cloning primates made this achievement a momentous one. (inverse.com)
  • Adding on top of that the successful cloning of primates with CRISPR-mediated gene deletions, the researchers have gone to great lengths to study the biological mechanisms for genetic diseases. (inverse.com)
  • This was how Chinese scientists in Shanghai recently managed to clone macaque monkeys 3 - the first cloning of primates. (chemistryworld.com)
  • In a meeting in Washington (3 December 2001) the researcher Tanja Dominko presented the results of monkey cloning (Macacus rhesus) when she worked at the Regional Center of Research in Primates of Beaverton, Oregon (USA). (sibi.org)
  • You can't say, taking this information in isolation, that it's easier to clone primates and humans,' he said. (irfi.org)
  • The scientists said they suspect that similar roadblocks exist for all primates -- the evolutionary grouping that includes monkeys and humans. (irfi.org)
  • According to Cell.com, previously it was assumed that this cloning technique would not work for primates, yet the Chinese biologists managed to refine the tech to make it suitable for cloning monkeys. (blastingnews.com)
  • But until now, they have been unable to make babies this way in primates, the category that includes monkeys, apes and people. (queerscifi.com)
  • These two are not the first primates to be cloned. (cmaaa.co.za)
  • Because of the great similarity between primates and humans, there is growing concern that humans could also be cloned in the future. (ecstaticgathering.com)
  • While eggs chemically triggered to develop don't have what it takes to make a viable embryo, it's a different story if the egg has been given the chromosomes of a cell from a more mature organism, through the technique of somatic-cell nuclear transfer used in cloning. (chemistryworld.com)
  • The most common technique to clone a viable embryo in the lab is called somatic cell nuclear transfer - a painstaking and time-consuming process conducted under a microscope. (scmp.com)
  • It needs both an egg cell, or oocyte, and a body cell, also known as a somatic cell - the latter of which is taken from the animal to be cloned. (scmp.com)
  • Although the genome-wide DNA demethylation is believed to be a hallmark of mammalian embryogenesis, previous study also indicated that the somatic form of dnmt1 ( dnmt1s ) is actually expressed at each stage of pre-implantation embryos and plays a role in the maintenance of DNA imprinting 8 . (nature.com)
  • The scientists also attempted to clone macaques using nuclei from adult donors, which is much more difficult. (wikipedia.org)
  • Exactly one year ago, the same researchers announced that they'd successfully cloned two macaques , named Hua Hua and Zhong Zhong. (inverse.com)
  • While they succeeded in obtaining cloned macaques, the numbers are too low to make many conclusions, except that it remains a very inefficient and hazardous procedure,' said Robin Lovell-Badge, an embryologist and head of the Division of Stem Cell Biology and Developmental Genetics at the Francis Crick Institute. (cmaaa.co.za)
  • There is now no barrier for cloning primate species, thus cloning humans is closer to reality. (bioedge.org)
  • The original monkey had been altered with CRISPR/Cas9 gene editing technology to give its clones a disrupted circadian rhythm so that scientists can learn how to treat humans with related disorders. (inverse.com)
  • Bioethicist Carolyn Neuhaus from The Hastings Center told Gizmodo that the research raises a lot of questions, including the fundamental concern that this gene deletion might not actually produce the same effects in humans as it did in the monkeys. (inverse.com)
  • The method had already been known to work in other animals, including mice and monkeys, but it had hitherto failed in humans. (chemistryworld.com)
  • In 2017, the Nankai University group produced the world's first piglets to be cloned using robots, although Liu said some parts of the process - including the removal of the egg cell's nucleus - still had to be done by humans. (scmp.com)
  • In the middle of the year 2001 a group of scientists said cloning humans might be easier than cloning animals. (irfi.org)
  • An Italian fertility doctor, Dr. Severino Antinori announced his intention to clone humans, so that he can help infertile couples to have children. (irfi.org)
  • I hope that this will not be used to give encouragement to those who wish to clone humans,' he said. (irfi.org)
  • The same techniques could be used to make combined humans and monkeys. (globalchange.com)
  • Other recent studies verified the presence of PAPP-A mRNA in granulosa cells of humans, monkeys, cattle, mice, and pigs. (bioone.org)
  • First true monkey clone - will humans be next? (blastingnews.com)
  • They've only been around for about eight weeks and are being introduced to the world today (Jan. 24), yet these baby primate clones have already done more for the future of scientific research than most humans will do in their whole lives. (qz.com)
  • Monkeys and humans have 97% of genes in common so if the right 1.6% were transferred from a human to a monkey we could land up with a monkey more human than animal. (globalchange.com)
  • But they warned that two monkeys engineered by Chinese researchers must not become a step toward cloning humans. (christian-heritage-news.com)
  • Previously, Mitalipov and his colleagues reported the first success in cloning human stem cells in 2013, successfully reprogramming human skin cells back to their embryonic state. (cnn.com)
  • In 2007, a research team led by Mitalipov announced they created t he first cloned monkey embryo and extracted stem cells from it. (cnn.com)
  • 5. In 2001, France and Germany requested the United Nations General Assembly to develop international conventions on human reproductive cloning, therapeutic cloning and research on stem cells. (who.int)
  • Scientists have used cloning technology to transform human skin cells into embryonic stem cells, an experiment that may revive the controversy over human cloning. (nationalrighttolifenews.org)
  • But they showed, for the first time, that it is possible to create cloned embryonic stem cells that are genetically identical to the person from whom they are derived. (nationalrighttolifenews.org)
  • The cloning breakthrough is instead being spun as skin cells into stem cells! (nationalrighttolifenews.org)
  • But that's far enough to produce embryonic stem cells that can be harvested for research and medicine - without the ethical quandaries presented by taking stem cells from human embryos discarded in IVF. (chemistryworld.com)
  • For instance, he wonders-just an intellectual puzzle, he assures me, that he would never want to do-What would happen if scientists injected human stem cells into a monkey embryo? (discovermagazine.com)
  • Scientists want to make cloned human embryos to get embryonic stem cells, which live inside early embryos and have the potential to cure a wide array of diseases. (irfi.org)
  • Scientists Clone First Monkey Voice of America - US scientists have cloned a monkey, using the resulting embryos to grow valuable stem cells. (litevi.com)
  • Some people are very uneasy about creating a human embryo and then dismembering it, however early the stage, to obtain embryonic stem cells from which useful tissues might be grown. (globalchange.com)
  • Although the method discovered by the Oregon team can be considered a type of cloning, team leader Shoukhrat Mitalipov says, " Our research is directed toward generating stem cells for use in future treatments to combat disease…[We do not] believe our findings might be used by others to advance the possibility of human reproductive cloning. (bigthink.com)
  • A similar approach has yielded stem cells from parthenogenetic monkey blastocysts ( New Scientist print edition, 6 October 2001). (newscientist.com)
  • This line of research will help to reduce the amount of macaque monkeys currently used in biomedical research around the world," he told The Independent . (inverse.com)
  • The MIT Technology Review reported that the researchers in Portland, Oregon, edited the DNA of a large number of one-cell embryos, specifically targeting genes associated with inherited diseases in those embryos. (cnn.com)
  • Out of over 300 embryos the researchers created, only five developed enough to implant them in a surrogate mother to mature. (inverse.com)
  • The researchers are undeterred, as the benefits of the cloned monkeys could be significant for drug research. (inverse.com)
  • The researchers stopped well short of creating a human clone. (nationalrighttolifenews.org)
  • After nuclear transfer, the researchers used a chemical stimulus to trigger growth of the embryos that developed to full term and produced live births. (chemistryworld.com)
  • Researchers say the macaque clones prefigure a not-so-distant future where labs will be able to create and conduct research on customizable populations of genetically uniform monkeys. (qz.com)
  • The birth of the cute monkey clones, while hopeful for medical research, raises ethical concerns, which the researchers acknowledge. (qz.com)
  • Texas A&M researchers announced that they had cloned a cat from the cumulus cell of an adult female cat. (hoaxes.org)
  • Oregon researchers announced the birth of Tetra, a rhesus macaque cloned by a process known as embryo splitting. (hoaxes.org)
  • Researchers at the University of Hawaii announce that mice have been successfully cloned from adult cells. (hoaxes.org)
  • Japanese researchers also announce the successful cloning of eight identical calves. (hoaxes.org)
  • Scientists in 1999 created Tetra, a rhesus monkey, but used what researchers consider a simpler cloning method that produces a more limited number of off spring. (cmaaa.co.za)
  • Chinese researchers have gone further and manipulated two human embryos with the CRISPR gene scissors. (ecstaticgathering.com)
  • That is why Chinese researchers have cloned a genetically modified monkey five times. (ecstaticgathering.com)
  • In 2000 ACT researchers in the United States cloned a gaur (Bos gaurus), an Asian ox with a then declining wild population. (asu.edu)
  • The researchers used cryopreserved gaur skin cells combined with an embryo of a domestic cow (Bos taurus). (asu.edu)
  • The world's first human clone of an adult has now been made, by an American biotechnology company in Massachusetts, Advanced Cell Technology. (globalchange.com)
  • A technological 'world first' happened when Scottish scientists recently performed the world's first true 'cloning' of a mammal. (creation.com)
  • Five clones of a gene-edited long-tailed macaque with several symptoms of genetic disease have been successfully bred, announced a team of scientists in Shanghai this week. (inverse.com)
  • For one thing, the team used the cloned monkeys' resulting psychiatric disorders - including "behaviors resembling anxiety, depression, and schizophrenia" - as signs that they had performed the experiment successfully. (inverse.com)
  • A decade later, an Asian carp was successfully cloned. (nyln.org)
  • Even an extinct animal, the Pyrenean ibex, was successfully cloned in 2009. (nyln.org)
  • A team from Münschen has already managed to raise pigs whose hearts have been successfully implanted in monkeys. (ecstaticgathering.com)
  • Unlike previous attempts to clone monkeys, the donated nuclei came from fetal cells, not embryonic cells. (wikipedia.org)
  • They then placed 21 of these ova into surrogate mother monkeys, resulting in six pregnancies, two of which produced living animals. (wikipedia.org)
  • In March, a surrogate mother gave birth to seven cloned piglets at the College of Artificial Intelligence at Nankai University in Tianjin. (scmp.com)
  • It's then stimulated to develop into an embryo, which is transplanted into a surrogate mother. (cmaaa.co.za)
  • In order for the cells to develop into human organs, the surrogate mother should carry the embryo. (ecstaticgathering.com)
  • It's certainly not the first time people have CRISPR-ed viable mammalian embryos," Greely said. (cnn.com)
  • The mechanisms underlying the appearance of asymmetry between cells in the early embryo and consequently the specification of distinct cell lineages during mammalian development remain elusive. (nature.com)
  • These findings can be integrated in a new unified framework that regards the early mammalian embryo as a self-organizing system. (nature.com)
  • Since Dolly's birth in 1996, scientists have cloned nearly two dozen kinds of mammals, including dogs, cats, pigs, cows and polo ponies, and have also created human embryos with this method. (queerscifi.com)
  • That month, scientists reported the first successful attempt to reproduce a large, adult mammal through cloning. (exposingsatanism.org)
  • A clone is an animal that developed from an egg produced from the nuclear DNA from non-germ cells of a single sexually mature adult. (ideosphere.com)
  • The phrase "produced from the nuclear DNA from non-germ cells of a single sexually mature adult" means that the rhesus monkey experiment performed at the Oregon Primate Research Center involving reproduction of embryos does not satisfy the claim. (ideosphere.com)
  • In this process, the cloned cell does not come from an adult. (hoaxes.org)
  • Speed while performing the procedure helped, they learned, and scientists discovered clones created out of cells from fetal tissue did better than when they used adult cells. (cmaaa.co.za)
  • Such 'adult' cloning means one can first see what the adult organism is like before cloning. (creation.com)
  • In the past five years, the team has also been able to improve the success rate of the development of cloned embryos from 21 per cent to 27.5 per cent, Liu said, as opposed to a 10 per cent success rate for manual operations. (scmp.com)
  • Thus if by "potential" one means "potency" - i.e., that the early human embryo already exists with a human nature that is already there, and has its own inherent power or capacity (provided by that human nature) to simply grow bigger and bigger through all the usual developmental stages through birth, then such a statement stands as accurate - both scientifically and philosophically. (lifeissues.net)
  • Otherwise, such a treaty would not recognize the inherent human nature of the early human embryo or fetus until after birth , and thus cloning them and using them for research - both "therapeutic" and "reproductive" -- would not be banned, and women undergoing "infertility treatments" could surely be put in danger. (lifeissues.net)
  • My 400-page doctoral dissertation was titled, A Philosophical and Scientific Analysis of the Nature of the Early Human Embryo (Georgetown University 1991). (lifeissues.net)
  • Previously, scientists in China were the first in the world to reveal attempts to modify genes in human embryos using CRISPR. (cnn.com)
  • As such, monkey cloning may be limited to medical research, where having more than one monkey with the same genes could help scientists compare the results of treatments or test under specific conditions. (engadget.com)
  • The resulting embryos, lacking the genes from sperm that promote full development, can't grow beyond the blastocyst stage that they reach in a few days. (chemistryworld.com)
  • However, the stuff of life is too serious to be playing God by wantonly adding new genes to people, by cloning them, or by adding significant amounts of human genes to alter animals into our own likeness. (globalchange.com)
  • Technically 1% of the human clone genes would have belonged to the cow - the mitochondria genes. (globalchange.com)
  • For a start it raises the biggest question of all: how many human genes does a cow or monkey have to gain before we give it human rights? (globalchange.com)
  • Rossant, J. & Vijh, K. M. Ability of outside cells from preimplantation mouse embryos to form inner cell mass derivatives. (nature.com)
  • In January 2019, scientists in China reported the creation of five identical cloned gene-edited monkeys, using the same cloning technique that was used with Zhong Zhong and Hua Hua, and the same gene-editing CRISPR-Cas9 technique allegedly used by He Jiankui in creating the first ever gene-modified human babies Lulu and Nana. (wikipedia.org)
  • According to Mu-ming Poo, the principal significance of this event is that it could be used to create genetically identical monkeys for use in animal experiments. (wikipedia.org)
  • Dr Mu-ming Poo, co-author of the research and director of the Chinese Academy of Sciences' Institute of Neuroscience, says that a population of genetically identical monkeys will be very useful for genetic research and drug development. (bioedge.org)
  • Edinburgh scientists have made a whole series of identical sheep, with the potential to create a flock of thousands of perfect clones. (globalchange.com)
  • In 1999 scientists managed to "clone" a rhesus macaque by splitting an early-stage macaque embryo into multiple parts, but that attempt only resulted in creating a couple of identical twins, and not true clones. (blastingnews.com)
  • If the clone had been allowed to continue beyond implantation it would have developed as Dr Cibelli's identical twin. (globalchange.com)
  • In Tetra's case, scientists split the embryos, much like what happens naturally when identical twins develop. (cmaaa.co.za)
  • However, identical twins (whether occurring naturally, or as in the recent media report of 'human cloning', from manipulation during in vitro fertilization procedures) result from a 'doubling up' of the DNA information at a very early stage of development in the womb. (creation.com)
  • Thus, if John Wesley had had a cloned offspring, there is no reason that the child would necessarily become a Christian, let alone a great evangelist - any more than an identical twin of Wesley would. (creation.com)
  • She is the first "cloned" primate by artificial twinning, which is a much less complex procedure than the DNA transfer used for the creation of Zhong Zhong and Hua Hua. (wikipedia.org)
  • The monkeys were named Zhong Zhong and Hua Hua, a reference to Zhonghua (Chinese: 中华, a Chinese name for China). (wikipedia.org)
  • Named Zhong Zhong and Hua Hua , the two baby monkeys are aged eight and six weeks respectively. (blastingnews.com)
  • The National Institutes of Health defines a human embryo as "the developing organism from the time of fertilization until the end of the eighth week of gestation. (archstl.org)
  • A clone is an organism that is a genetic copy of an existing one. (who.int)
  • A cloned embryo-like a natural embryo-is an individual organism, a member of its (in this case, human) species. (nationalrighttolifenews.org)
  • What happens in reproductive cloning is that a duplicate copy of another organism is made. (nyln.org)
  • Ever since, a number of mammals have been cloned - cows, pigs, cats and rhesus monkeys. (nyln.org)
  • Five beagles were created by cloning fibroblast cells that express a red florescent gene produced by sea anemones. (mentalfloss.com)
  • Moreover, FFPE-positive liver tissues and a negative control (chicken embryo fibroblast cells) samples were also tested. (cdc.gov)
  • The MIT Technology Review published on Wednesday a news report about the first-known experiment to create genetically modified human embryos in the United States using a gene-editing tool called CRISPR. (cnn.com)
  • It's not the first time anybody has CRISPR-ed human embryos. (cnn.com)
  • He pointed out that the new research reportedly involved earlier, more delicate embryos, and CRISPR reportedly was still demonstrated as efficient. (cnn.com)
  • Before any person receives a CRISPR-ized pig organ there will be years of negotiations with regulators, close work with transplant surgeons, and costly experiments putting pig organs in monkeys. (technologyreview.com)
  • Here we report genome-wide composition, patterning, and stage-specific dynamics of DNA methylation in pre-implantation rhesus monkey embryos as well as male and female gametes studied using an optimized tagmentation-based whole-genome bisulfite sequencing method. (nature.com)
  • We therefore decided to investigate comprehensively the global and high-resolution DNA methylation dynamics during early development of a non-human primate (rhesus monkey, Macaca mulatta ). (nature.com)
  • In theory, this makes human cloning more realistic given the genetic similarities between monkeys and our own species. (engadget.com)
  • The efficiency of cloning, defined as the proportion of transferred embryos that result in viable offspring, is approximately 2 to 3% for all species. (sibi.org)
  • However, in cattle, average cloning efficiency is higher than in other species, ranging from 5 to 20% [10 -15]. (sibi.org)
  • Among the factors thought to contribute to the greater success in cloning cattle are the relatively late embryonic genome activation specific for this species [16 -18] and the optimization of reproductive technologies, such as in vitro embryo production and embryo transfer, brought about by the cattle industry [19]. (sibi.org)
  • Recent experimentation that has cultured lab-grown monkey embryos for up to 20 days and the possibility of creating human-monkey chimeras - beings that contain genetic codes from two different species - has further pushed the envelope on embryonic stem cell research. (thetablet.org)
  • Cross-species cloning does count, as long as the other requirements are met. (ideosphere.com)
  • It will unquestionably spark debate, however, over ethical aspects of potentially cloning yet another primate species, Homo Sapiens . (blastingnews.com)
  • Not just bacteria, but also some of the plant, amphibian and reptile species reproduce in this way, by 'cloning' themselves without the need for both a mother and father. (creation.com)
  • In the paper, they explain that the ability to produce gene-edited clones will help them study diseases related to disrupted circadian rhythm , including Alzheimer's disease, depression, and other sleep problems. (inverse.com)
  • The team removed the nucleus from monkey eggs and replaced it with DNA from the fetus, implanting the resulting eggs in female monkeys for them to give birth. (engadget.com)
  • 7. "[footnote 16]: The cloning procedure supplies the oocyte with a complete set of chromosomes, all of which are contained in the nucleus which is transferred into the denucleated oocyte. (lifeissues.net)
  • The method described on Wednesday by Oregon State University scientists in the journal Cell, would not likely be able to create human clones, said Shoukhrat Mitalipov, senior scientist at the Oregon National Primate Research Center. (nationalrighttolifenews.org)
  • 2. Over the years, the international community has tried without success to build a consensus on an international convention against the reproductive cloning of human beings. (who.int)
  • 3. Creating awareness among ministries of health in the African Region will provide them with critical and relevant information on the reproductive cloning of human beings and its implications to the health status of the general population. (who.int)
  • 7. The WHO Regional Committee for Africa is invited to review this document for information and guidance concerning reproductive cloning of human beings. (who.int)
  • 3. Media reports on nuclear transfer are usually about one form, reproductive nuclear transfer, also known as reproductive cloning of human beings . (who.int)
  • Since the term "born" has been used as an essential part of the definition of " reproductive cloning " used by Weissman, the National Academy of Sciences, etc., then it is critical to use the accurate term with the proper meaning. (lifeissues.net)
  • Reproductive cloning is a process that has been around for a long time. (nyln.org)
  • However, with reproductive cloning, same-sex couples no longer have to seek such methods because they can have a child that is truly their own. (nyln.org)
  • A live birth of a primate clone will occur by January 1, 2000 and be reported within 6 months. (ideosphere.com)
  • Embryos" created by the procedure do not contain any paternal chromosomes - just two sets of chromosomes from the mother - and so cannot develop into babies. (newscientist.com)
  • On closer inspection, Hemmati-Brivanlou realized that the lack of activin had stopped the development of the mesoderm, a layer of tissue in an embryo that eventually develops into muscle, bone, and connective tissue. (discovermagazine.com)
  • He noted, critics will evoke, 'the slippery slope argument of this being one step closer to human cloning. (cmaaa.co.za)
  • The scientists added matrix RNA and trichostatin A to the cloned genome in order to significantly reduce the probability the animals they cloned would die. (blastingnews.com)
  • They extracted nuclei from the fibroblasts of an aborted fetal monkey (a crab-eating macaque or Macaca fascicularis) and inserted them into egg cells (ova) that had had their own nuclei removed. (wikipedia.org)
  • Pan said the robotic cloning technique - as well as the broader science of micro-manipulation of cells - could have a wide range of applications in animal husbandry, including assisted reproduction and selective breeding. (scmp.com)
  • Nearly all the cells in the stalled embryo had turned into brain cells, simply because a single protein had been stopped. (discovermagazine.com)
  • A fertilized egg is totipotent, meaning that its potential is total, and as the fertilized egg divides all the cells in the embryo remain totipotent until the fertilized egg has reached the 8/16-cell stage. (biomedcentral.com)
  • In theory, and to some extent in practice, an 8-cell embryo can be divided into eight single cells, and each cell has the potential of generating an individual if implanted in a woman's uterus. (biomedcentral.com)
  • In order to avoid this problem, the Japanese doctor Hiromitsu Nakauchi wants to create a rat embryo with human cells. (ecstaticgathering.com)
  • The breakthrough follows similar success with monkey skin cells in 2007. (bigthink.com)
  • They achieved similar success with monkey cells in 2007. (bigthink.com)
  • This is why cloning has long fascinated science fiction writers, because it conjures up the image of, say, getting a carbon copy of an Einstein or a Hitler, (perhaps even after their death, if all the DNA from one of their cells were somehow preserved). (creation.com)
  • Vaccinia vaccine is made of live vaccinia virus derived from plaque purification cloning of Dryvax® (calf lymph vaccine, New York City Board of Health Strain) and grown in African Green Monkey kidney (Vero) cells and tested to be free of adventitious agents. (cdc.gov)
  • From the perspective of research that would ultimately make germline editing safer and more effective, the earlier embryos will provide more relevant information," he said. (cnn.com)
  • That's why Father Pacholczyk, director of education at the National Catholic Bioethics Center in Philadelphia, said that the efforts to help people understand the immorality of embryo reserch, including human cloning, must focus on humanizing the issue and appreciating our own embryonic origins, not just on the desired results of embryonic or other types of stem-cell research. (archstl.org)
  • A decade later, cloning came to the forefront in Missouri with the narrow passage of Amendment 2, a ballot initiative in 2006 that constitutionally protects embryonic stem-cell research and human cloning. (archstl.org)
  • The Catholic Church has always held that stem-cell research and therapies are morally acceptable, as long as they don't involve the creation and destruction of human embryos. (archstl.org)
  • And in fact, Mu-ming Poo, Ph.D., a senior investigator at the Academy's Institute of Neuroscience and one of the authors on the papers, says the research could actually result in a net decrease to monkey suffering in scientific labs. (inverse.com)
  • But it is an important step in research because it doesn't require the use of embryos in creating the type of stem cell capable of transforming into any other type of cell in the body. (nationalrighttolifenews.org)
  • If it works, this automated system could be developed into a cloning kit that any company or research institution can buy to free scientists from labour-intensive, time-consuming manual cloning, said Pan Dengke, a former researcher with the Chinese Academy of Agricultural Sciences who helped produce China's first cloned pig in 2005. (scmp.com)
  • TORONTO (CNS) - The international scientific body governing stem cell research is abandoning the absolute 14-day limit on culturing human embryos in the laboratory, putting pressure on Canada's law prohibiting the practice. (thetablet.org)
  • On May 26, the International Society for Stem Cell Research said it was relaxing the 14-day rule, which prohibited experiments on human embryos past 14 days of development in the lab. (thetablet.org)
  • On April 11, 2003, Washington Post Staff Writer, Rick Weiss, reported 'New research suggests that it may be a lot harder to clone people than to clone other animals, an unexpected scientific twist that could influence the escalating congressional debate over human cloning and embryo research. (irfi.org)
  • But opponents of human embryo research were afraid that the new research not only identifies previously unrecognized hurdles to human cloning, but also points the way to overcoming those hurdles. (irfi.org)
  • The team says it adheres to international guidelines for animal research set by the US National Institutes of Health for this experiment and are encouraging other scientists to engage in debate with their work and the ethics of cloning in order to develop an acceptable, successful approach. (qz.com)
  • This vaccine was made possible by the cell culture research of John Franklin Enders , Thomas Huckle Weller , and Frederick Chapman Robbins , who were awarded a Nobel Prize for their discovery of a method of growing the virus in monkey kidney cell cultures. (wikipedia.org)
  • This could eliminate one of the main sources of ethical controversy in this research," says Bob Lanza, head of research at the cloning company Advanced Cell Technology in Worcester, Massachusetts. (newscientist.com)
  • The new work by scientists in Pittsburgh provides an explanation for why hundreds of attempts to clone monkeys have all failed despite successes in several other mammals. (irfi.org)
  • It remains a big problem for the cloning technology," an anonymous Shanghai-based life scientist who was not involved in the story told South China Morning Post . (inverse.com)
  • The newly discovered obstacle makes it more likely than ever that rogue scientists' recent claims to have created cloned babies were fraud. (irfi.org)
  • They hope more monkey babies will be born soon from these embryos. (cmaaa.co.za)
  • On the medical side, concerns raised include life expectancy as cloned mammals only show a low success rate. (nyln.org)
  • Reproduction and birth have always been subjects that quickly get people's attention, especially when you're talking about the extreme limits of the phenomena: multiple-births, clones, or the birth of creatures that seem to defy what some believe to be the natural order. (hoaxes.org)
  • Gathered here are examples of birth hoaxes throughout the ages, from the very recent claims about human cloning (which seem more and more likely to be a hoax) to the ancient. (hoaxes.org)
  • Dr. Brigitte Boisselier, chief executive of Clonaid, convened a press conference to announce the recent birth of 'Eve', a baby girl cloned from the skin cell of her 31-year-old mother. (hoaxes.org)
  • November 27, 2002: Imminent Birth of Human Clone? (hoaxes.org)
  • Dr. Severino Antinori, an Italian physician, announced that a woman who had participated in a scientific project that he assisted with would give birth to a human clone in January. (hoaxes.org)
  • The birth of these clones also brings up ethical issues. (cmaaa.co.za)
  • In the Chinese experiment, 79 embryos were created and implanted into 21 surrogates. (bioedge.org)
  • Just one transplant experiment using large animals, like putting a pig heart in a monkey, costs $100,000, he says. (technologyreview.com)
  • December 27, 2002: First Human Clone Born? (hoaxes.org)
  • For example, in sheep less than one embryo in 300 develops normally. (irfi.org)
  • The egg begins dividing and growing once it is stimulated then it develops into an embryo which can be implanted into a gestational surrogate where it will be carried to term. (nyln.org)