• It is now known that a variety of light chain subunits (ANTIGENS, CD98 LIGHT CHAINS) can dimerize with the heavy chain. (wakehealth.edu)
  • This adhesion occurs as part of the transitory initial encounters between T cells and Antigen Presenting Cells before T cell activation , when T cells are roaming the lymph nodes looking at the surface of APCs for peptide:MHC complexes the T-cell receptors are reactive to. (wikidoc.org)
  • A heterodimeric protein that is a cell surface antigen associated with lymphocyte activation. (wakehealth.edu)
  • CD58 , or lymphocyte function-associated antigen 3 (LFA-3), is a cell adhesion molecule expressed on Antigen Presenting Cells (APC), particularly macrophages . (wikidoc.org)
  • The CD8 antigen, acting as a coreceptor, and the T-cell receptor on the T lymphocyte recognize antigen displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. (wikidoc.org)
  • B-lymphocyte antigen CD20 or CD20 is an activated- glycosylated phosphoprotein expressed on the surface of all B-cells beginning at the pro-B phase ( CD45 R+, CD117 +) and progressively increasing in concentration until maturity. (wikidoc.org)
  • This gene encodes a B-lymphocyte surface molecule that plays a role in the development and differentiation of B-cells into plasma cells . (wikidoc.org)
  • Carcinoembryonic antigen (CEA) is a glycoprotein involved in cell adhesion . (wikidoc.org)
  • The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. (wikidoc.org)
  • Antigens, CD47" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (rush.edu)
  • Below are the most recent publications written about "Antigens, CD47" by people in Profiles. (rush.edu)
  • The initial characterization of this protein revealed one identifiable heavy chain (ANTIGENS, CD98 HEAVY CHAIN) and an indeterminate smaller light chain. (wakehealth.edu)
  • The protein has no known natural ligand [4] and its function is to enable optimal B-cell immune response, specifically against T-independent antigens. (wikidoc.org)
  • The average number of O linked chains is 12 per molecule. (wikidoc.org)
  • The targeted genes and miRNA molecule were clarified using the mice middle cerebral artery occlusion-reperfusion (MCAO/R) model. (bvsalud.org)
  • In humans, the carcinoembryonic antigen family consists of 29 genes, 18 of which are normally expressed. (wikidoc.org)
  • A membrane-bound tumor necrosis family member found primarily on activated T-LYMPHOCYTES that binds specifically to CD30 ANTIGEN. (wakehealth.edu)
  • It binds to CD2 (LFA-2) [3] [4] on T cells and is important in strengthening the adhesion between the T cells and Professional Antigen Presenting Cells. (wikidoc.org)
  • Its major physiologic role appears to be neutralization of heparin-like molecules on the endothelial surface of blood vessels, thereby inhibiting local antithrombin III activity and promoting coagulation. (wikidoc.org)
  • Mucin-like molecules are a new family of glycoproteins present in tissues of the hematopoietic system. (bdbiosciences.com)
  • Hammarstrom S. The carcinoembryonic antigen (CEA) family: structures, suggested functions and expression in normal and malignant tissues. (wikidoc.org)
  • The term "oncotarget" encompasses all molecules, pathways, cellular functions, cell types, and even tissues that can be viewed as targets relevant to cancer as well as other diseases. (oncotarget.com)
  • All four contain an extracellular ligand binding domain, a transmembrane domain, and an intracellular domain that can interact with a multitude of signaling molecules and exhibit both ligand-dependent and ligand-independent activity. (iiab.me)
  • Because of this specificity, groups of cells that express the same type of cadherin molecule tend to cluster together during development , whereas cells expressing different types of cadherin molecules tend to separate. (wikidoc.org)
  • The heparin:PF4 complex is the antigen in heparin-induced thrombocytopenia , an idiosyncratic autoimmune reaction to the administration of the anticoagulant heparin . (wikidoc.org)
  • Demonstration of tumor-specific antigens in human colonic carcinomata by immunological tolerance and absorption techniques. (wikidoc.org)
  • CD164 is a 80-90 kDa, mucin-like molecule present on CD34+ cells during the early stages of B cell, erythroid cell and myelomonocytic cell development. (bdbiosciences.com)
  • This graph shows the total number of publications written about "Junctional Adhesion Molecule B" by people in UAMS Profiles by year, and whether "Junctional Adhesion Molecule B" was a major or minor topic of these publications. (uams.edu)
  • [1] The following year a new but related antigen was discovered in a Mrs Yus for whom an antigen in this system is also named. (wikidoc.org)
  • This chemokine is released from alpha-granules of activated platelets during platelet aggregation, and promotes blood coagulation by moderating the effects of heparin -like molecules. (wikidoc.org)
  • In 1972 a numerical system for the antigens in this blood group was introduced. (wikidoc.org)
  • Glycophorin A and glycophorin B carry the blood group MN and Ss antigens respectively. (wikidoc.org)
  • This competition of the virus with ECM molecules for receptor binding likely explains the recently found correlation between the affinity of LCMV binding to alpha-DG, tissue tropism, and pathological potential. (nih.gov)
  • A component of the B-cell antigen receptor that is involved in B-cell antigen receptor heavy chain transport to the PLASMA MEMBRANE. (rush.edu)
  • T cell-targeted immunomodulators such as monoclonal antibodies against PD-1 or CTLA-4 are used in combination with T cells engineered with chimeric antigen receptor (CAR) (CAR-T cells) against several malignancies in clinical trials. (bdbiosciences.com)
  • An introduction to chimeric antigen receptor (CAR) T-cell immunotherapy for human cancer. (bdbiosciences.com)
  • Cluster of differentiation CD79A also known as B-cell antigen receptor complex-associated protein alpha chain and MB-1 membrane glycoprotein , is a protein that in humans is encoded by the CD79A gene . (wikidoc.org)
  • The CD79a protein together with the related CD79b protein, forms a dimer associated with membrane-bound immunoglobulin in B-cells , thus forming the B-cell antigen receptor (BCR). (wikidoc.org)
  • This occurs in a similar manner to the association of CD3 with the T-cell receptor , and enables the cell to respond to the presence of antigens on its surface. (wikidoc.org)
  • CD154 se vezuje za CD40 na antigen-prezentirajućim ćelijama (APC), posledica čega su mnogobrojni efekti koji zavise of tipa ciljne ćelije. (wikipedia.org)
  • This ready-to-use, pre-coupled magnetic beads are in uniform particle size and narrow size distribution with large surface area, which is conducive to convenient and fast capture target molecules with high specificity and achieve magnetic separation. (creativebiomart.net)
  • From NCBI Gene: This gene encodes a transmembrane sialomucin and cell adhesion molecule that regulates the proliferation, adhesion and migration of hematopoietic progenitor cells. (nih.gov)
  • A sialomucin protein that functions as a cell adhesion molecule. (nih.gov)
  • This subunit of DG is a highly versatile cell surface molecule that provides a molecular link between the extracellular matrix (ECM) and a beta-DG transmembrane component, which interacts with the actin-based cytoskeleton. (nih.gov)
  • All four contain an extracellular ligand binding domain, a transmembrane domain, and an intracellular domain that can interact with a multitude of signaling molecules and exhibit both ligand-dependent and ligand-independent activity. (iiab.me)
  • Antigens, CD4" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (uams.edu)
  • 55-kDa antigens found on HELPER-INDUCER T-LYMPHOCYTES and on a variety of other immune cell types. (uams.edu)
  • CD4 antigens are members of the immunoglobulin supergene family and are implicated as associative recognition elements in MAJOR HISTOCOMPATIBILITY COMPLEX class II-restricted immune responses. (uams.edu)
  • Cancer cells and the tumor microenvironment, however, can adopt these immunological checkpoints to pose as "self" molecules and evade the natural defense of the body's own immune system. (bdbiosciences.com)
  • Below are the most recent publications written about "Antigens, CD4" by people in Profiles over the past ten years. (uams.edu)