AnatomyOrganismsDiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPhenomena and ProcessesInformation Science
Molecular WeightChromatography, GelChemical FractionationChromatography, High Pressure LiquidBody WeightWeight LossWeight GainElectrophoresis, Polyacrylamide GelBirth WeightAmino AcidsKineticsSubcellular FractionsAmino Acid SequenceMolecular Sequence DataCentrifugation, Density GradientCattleMacromolecular SubstancesHydrogen-Ion ConcentrationChromatography, Ion ExchangeChromatographyImmunodiffusionIsoelectric PointChromatography, AffinityLiverUltracentrifugationConcanavalin AListeria monocytogenesPronaseMacrophages
UltrafiltrationWater-solublePolydispersity indexSerumHighChromatographyProtein fractionSpeciesBiologyAverage molecular weightSignificantlyConcentrationAnalysesCharacterizationCrudeMicrobialMoleculesOrganicMembranesProteinsAminoMassMobilityGeneticCompoundsHigherStructureReactionPatientsMultipleComponentsProductionPresence
Ultrafiltration1
  • The molecular weight of MSF was determined by ultrafiltration to be less than 10,000, and the modulating activity of MSF was not altered by heating at 100°C for 30 minutes or freezing at -70°C for six months. (missouristate.edu)
Water-soluble1
  • Other mechanisms by which substances can be absorbed in the gastrointestinal tract include the passage of small water-soluble molecules (molecular weight up to around 200) through aqueous pores or carriage of such molecules across membranes with the bulk passage of water (Renwick, 1993). (europa.eu)
Polydispersity index2
Serum5
  • Macrophage suppression has been shown to be mediated by a unique, low molecular weight fraction of murine serum. (missouristate.edu)
  • This study quantifies the experimental uncertainty for LC retention time, mass measurement precision, and ion abundance obtained from replicate nLC-dual ESI-FT-ICR analyses of the low molecular weight fraction of serum. (elsevierpure.com)
  • 10-kDa fraction of components from the high-abundance proteins in a pooled serum sample derived from ovarian cancer patients. (elsevierpure.com)
  • These measures of analytical reproducibility establish a statistical rationale for differentiating healthy and disease patient populations for the elucidation of biomarkers in the low molecular fraction of serum. (elsevierpure.com)
  • A tetrameric protein, molecular weight between 50,000 and 70,000, consisting of 4 equal chains, and migrating on electrophoresis in 3 fractions more mobile than serum albumin. (bvsalud.org)
High20
  • The difference of molecular compositions between S and S1 explained our previous observation that S1 exhibited different anticancer profile in some cancer cell lines, compared with S. Since we observed this unique LMWF, we compared the cytotoxic effects of a LMWF and a high molecular weight fucoidan (HMWF) in two breast cancer cell lines-MCF-7 and MDA-MB-231. (nih.gov)
  • Our results indicate that the active factor is either a high molecular weight protein or protein complex and is not the respiratory protein hemocyanin. (nature.com)
  • A very high molecular weight fraction contained alpha crystallin material. (cdc.gov)
  • Unexpectedly high field-effect mobility of a soluble, low molecular weight oligoquaterthiophene fraction with low polydispersity. (mpg.de)
  • High performance size exclusion chromatography (HPSEC) showed that it was a homogeneous polysaccharide fraction. (unboundmedicine.com)
  • In this context, desired property profiles (weight lightweight, high toughness, short cycle times during production) can often only be achieved by using composites and multilayer films/components in which different thermoplastics are equipped with functional additives. (fraunhofer.de)
  • The average molecular weights are often determined by intrinsic viscosity measurement or high-temperature gel permeation chromatography (HT-GPC), as it is state-of-the-art for semi-crystalline polyolefins. (fraunhofer.de)
  • NulOs were predominantly present in the high-molecular weight fraction (47.2-84.3% of all detected NulOs), while sulfated glycoconjugates were distributed across the molecular weight fractions. (tudelft.nl)
  • Difficulty was found on trying to fractionate the high molecular weight sample of the tripropionate. (phddata.org)
  • the remainder was likely to be associated with high molecular weight globulins. (bmj.com)
  • The high molecular weight component, about 130 000-230 000, was the most important 203Pb binding site. (bmj.com)
  • When studying a polymer, the most relevant average depends on the property being investigated: for example, some properties may be more affected by molecules with high molecular weight than those with low molecular weight, so the weight average is chosen since it highlights the presence of molecules with high molecular weight. (doitpoms.ac.uk)
  • Owing to their physical properties, such as relatively high molecular weight, linear structure, and nonspecific binding, ASOs present unique challenges in ƒ u determination through traditional techniques. (aspetjournals.org)
  • 10 It is used to separate molecules based on their difference in hydrophobicity, and the technique has been presented as an efficient mode to remove dimers and high molecular weight (HMW) aggregates as a polishing step in a MAb purification process. (biopharminternational.com)
  • According to WP 2 the following detailed analysis were conducted on the high molecular weight fractions of Rhine river, estuarine, and North Sea samples during summer and fall 2001. (europa.eu)
  • The types of compounds present in aromatic concentrates derived from high-boiling petroleum distillates can be estimated from a gel permeation chromatographic (gpc) analysis by the use of tables developed from extensive gpc and mass-spectral analyses on fractions from four crude oils. (cdc.gov)
  • Immature soot was characterized by short and amorphous nanostructures, BrC absorption, high polycyclic aromatic hydrocarbon (PAH) fractions, and refractory organic carbon that partially formed pyrolytic carbon during thermal-optical analysis. (lu.se)
  • Occupational exposure to high-molecular-weight allergens is a risk factor for the development and pathogenesis of IgE-mediated respiratory disease. (cdc.gov)
  • Occupations where of viral, prokaryote, or eukaryote origin) and an even greater high-molecular-weight allergens have been characterized number of abiotic (physical and chemical) agents have include seafood processing (tropomysin), dairy, poultry, been associated with adverse health outcomes. (cdc.gov)
  • 6]. Some of the best examples of high-molecular-weight sectors, workers are at increased risk of becoming sensitized occupational allergens are the fungal enzymes. (cdc.gov)
Chromatography5
  • A low molecular-weight polysaccharide named BIWP2 was purified from the fruit bodies of Bulgaria Inquinans (Fries) via hot-water extraction, followed by freeze-thawing and gel filtration chromatography on Sephadex G-75. (unboundmedicine.com)
  • 3H]CFT binding sites were separated into three protein fractions by anion-exchange chromatography. (aspetjournals.org)
  • Size-exclusion chromatography indicated [3H]CFT bound to a single protein in each fraction (apparent molecular weight, 170 kDa). (aspetjournals.org)
  • The average molecular weight of a polymer sample can be determined using a variety of techniques, such as gel permeation chromatography, light-scattering measurements and viscosity measurements, and the type of average that is yielded depends on the technique. (doitpoms.ac.uk)
  • The glycopeptide fractions were further purified by gel-permeation chromatography and two purified glycopeptides, D2H, D2L, were obtained. (scirp.org)
Protein fraction3
  • After extraction of lipid by a methanol/chloroform mixture, about 75% of the lead was found to be associated with the protein fraction. (bmj.com)
  • Arrow indicates the 32-KDa protein fraction. (cdc.gov)
  • We obtained protein components from maple syrup by ammonium sulfate precipitation, and treatment with the protein fraction of maple syrup (MSpf) was found to exhibit a potential antitumor effect. (spandidos-publications.com)
Species3
  • In this study, we examined five fucoidans extracted from the same seaweed species Undaria pinnatifida but from different geological locations, and compared them to the laboratory-grade fucoidan from Sigma (S). The five products differed in molecular composition. (nih.gov)
  • A simple two-level grouping algorithm was applied to the more than 7000 isotope clusters found in each replicate and identified 497 molecular species that appeared in at least four of the replicates. (elsevierpure.com)
  • In addition, a representative set of 231 isotope clusters, corresponding to 188 unique molecular species, were manually interpreted to verify the automated algorithm and to set its tolerances. (elsevierpure.com)
Biology2
  • nature structural & molecular biology Abstract In the early stages of mitosis, cohesin is released from chromosome arms but not from centromeres. (cbinsights.com)
  • However, with ever-increasing knowledge of the biology and molecular heterogeneity of myeloid neoplasms comes the ability to further classify MDS with prognostic and predictive relevance. (medscape.com)
Average molecular weight9
Significantly2
  • Results indicated that the molecular weight is a critical factor in determining the anti-cancer potential of fucoidan, from the New Zealand U. pinnatifida , as the LMWF exhibited a dose-dependent inhibition on the proliferation of breast cancer cells, significantly better than the HMWF, in both cell lines. (nih.gov)
  • Cell proliferation assays demonstrated that treatment with the more than 10,000 molecular weight fraction significantly inhibited viability in DLD‑1 cells. (spandidos-publications.com)
Concentration2
  • We will characterize the DOM pool and its molecular weight fractions and determine the trace metal concentration (Fe, Cu, Cd, Mn) and speciation in the different DOM molecular weight fractions. (europa.eu)
  • Immunologically mediated OA accounts for approximately weight allergens in industrial settings and describe the 90% of cases [9], but the severity of disease is dependent main enzymes that have been associated with occupational on the concentration, route, agent of exposure, and the sensitization and asthma. (cdc.gov)
Analyses1
  • Stable incorporations of T-DNA into the citrus genome have been confirmed with both histochemical staining of GUS activity and molecular analyses. (springer.com)
Characterization2
  • Further molecular characterization of active factors and their cellular targets is warranted on account of the magnitude of the effects reported here and their potential relevance for nervous system repair. (nature.com)
  • Drug unbound fraction (ƒ u ) characterization is a key consideration in pharmacokinetic and pharmacodynamic (PK/PD) modeling, assuming only unbound drug can interact with the target, and therefore has direct implications in the efficacy and potential toxicity of the drug. (aspetjournals.org)
Crude1
  • The amount of over 2 kDa low molecular weight fraction (LMWF) of the New Zealand crude fucoidan (S1) was larger than that of S, and this fraction was unique, compared to the other four fucoidans. (nih.gov)
Microbial2
  • BACKGROUND: Condensed tannin (CT) fractions of different molecular weights (MWs) may affect rumen microbial metabolism by altering bacterial diversity. (upm.edu.my)
  • Biological weighting functions for the response of microbial community to the exposure to UV radiation and its subsequent recovery are determined. (europa.eu)
Molecules5
  • Based on the results, we have proposed a new research strategy called "bioorganometallics," in which organic-inorganic hybrid molecules are used as molecular probes to analyze biological systems. (go.jp)
  • It has a value greater than or equal to one: it is equal to one only if all the molecules have the same weight (i.e. if it is monodisperse), and the further away it is, the larger the spread of molecular weights. (doitpoms.ac.uk)
  • The molecular weight distribution can be shown graphically by plotting the number of molecules against the molecular weight. (doitpoms.ac.uk)
  • Olfactory receptors are supposed to act not only as molecular sensors for odorants but also as cell recognition molecules guiding the axons of olfactory neurons to their appropriate glomerulus in the olfactory bulb. (jneurosci.org)
  • in the cilia recognizing odorous molecules from the environment and in the axons recognizing molecular cues in the olfactory bulb. (jneurosci.org)
Organic1
  • The nonlinear isotherm parameters were determined from three frontal experiments at different organic fractions. (aiche.org)
Membranes1
  • Following centrifugation, the digest supernatant was sequentially ultrafiltered using 10K and 1K molecular weight cut-off membranes. (usda.gov)
Proteins1
  • These data indicate that olfactory receptor (OR) proteins are indeed present in the axonal processes and nerve terminals of olfactory sensory neurons, thus supporting the notion that ORs may participate in the molecular processes underlying the fasciculation and targeting of olfactory axons. (jneurosci.org)
Amino2
  • These factors are short peptides with molecular weights of 1,000 to 7,000 that contain the amino acid histidine. (usda.gov)
  • They were composed of glucose and mannose and 10 different amino acids and with molecular weights of 18,000 and 8000 Da, respectively. (scirp.org)
Mass5
  • Mass spectrometry analysis and quantification assays identified nonulosonic acids (NulOs, e.g., bacterial sialic acids) and sulfated groups contributing to the negative charge in all EPS fractions. (tudelft.nl)
  • This section should strictly be called "Polymer molecular mass", but in polymer science it is more common to refer to molecular weight than molecular mass, so this convention will be continued here. (doitpoms.ac.uk)
  • For a fraction from the gpc analysis, the retention volume and the molecular weights (from mass spectrometer) suffice to indicate the types of compounds that predominate. (cdc.gov)
  • Mature soot was characterized by ordered nanostructures, BC absorption, low PAH mass fractions, and mass dominated by elemental carbon. (lu.se)
  • Li K, Al-Rudainy B, Sun M, Wallberg O, Hulteberg C, and Tunå P. Membrane Separation of the Base-Catalyzed Depolymerization of Black Liquor Retentate for Low-Molecular-Mass Compound Production. (lu.se)
Mobility1
  • TPHCWG 1997b) has defined its TPH fractions by the mobility of constituents in order to address this question of predicting risks associated with TPH contamination. (cdc.gov)
Genetic2
  • With all six genotypes of citrus tested including Eureka lemon, a cultivar difficult to be transformed, our results demonstrate that the kn1 gene may provide an effective molecular tool to enhance genetic transformation efficiencies of various citrus varieties. (springer.com)
  • Evidence of clonality often supports the diagnosis of MDS and may manifest as recurrent karyotypic or molecular genetic abnormalities, although these findings are not necessary to fulfill the diagnostic criteria. (medscape.com)
Compounds2
  • These tables provide a rapid method for determining which types of compounds are present in a gpc fraction before attempting to develop quantitative data. (cdc.gov)
  • in soluble barium compounds), and 15 mg/m 3 (total dust) and 5 mg/m 3 (respirable fraction) for insoluble barium sulfate. (cdc.gov)
Higher3
  • Inclusion of higher-MW CT fractions F1 and/or F2 decreased the relative abundance of minor genera such as Ruminococcus, Streptococcus, Clostridium XIVa and Anaeroplasma but increased the relative abundance of Acinetobacter, Treponema, Selenomonas, Succiniclasticum and unclassified Spirochaetales compared with the control and lower-MW CT fractions. (upm.edu.my)
  • The loss of alpha crystallin from the isoelectric focusing pattern was due to aggregation to higher molecular weight particles which could not enter the gel. (cdc.gov)
  • trimers and higher molecular weight polymers. (aiche.org)
Structure3
  • Effect of molecular weight on the structure and crystallinity of poly(3-hexylthiophene). (mpg.de)
  • However, the understanding of the molecular structure of the coupling agents obtained in this way is currently incomplete, as there are no suitable analytical measurement protocols for them. (fraunhofer.de)
  • This truncated variant allows consistent and easy crystallization, but importantly the structure was used as a search model in molecular replacement, allowing the full-length IdmH structure to be determined to 2.7 Å resolution. (iucr.org)
Reaction1
  • Finally, combined quantum mechanical/molecular mechanical (QM/MM) modelling of the IdmH reaction shows that the active site of the enzyme provides an appropriate environment to promote indane-ring formation, supporting the assignment of IdmH as the key Diels-Alderase catalysing the final step in the biosynthesis of indanomycin through a similar mechanism to other recently characterized Diels-Alderases involved in polyketide-tailoring reactions. (iucr.org)
Patients2
  • 500 Da) dialysate fractions from patients with uremia substantially inhibit this enzyme. (medscape.com)
  • Early prophylaxis in surgical patients with low-molecular-weight heparin (LMWH) has been associated with significant reductions in postoperative venous thrombosis. (medscape.com)
Multiple2
  • Detection of multiple binding components for [3H]CFT labeled sites by these drugs varied in each fraction. (aspetjournals.org)
  • After multiple injections, eggs were collected from the hens, and IgY fractions were prepared from the yolks and then affinity-purified antibodies were prepared using GFP conjugated to an agarose matrix. (antibodiesinc.com)
Components1
  • The elevated AAEs and a major fraction of the BrC absorption were assigned to refractory soot components. (lu.se)
Production1
  • Muconic acid production using engineered Pseudomonas putida KT2440 and guaiacol-rich fraction derived from Kraft lignin. (lu.se)
Presence1
  • platelet aggregation to vWF in the presence of ristocetin is proportional to hemostatically active fraction of vWF. (medscape.com)