BioinformaticsMechanismsBiochemistryComputationalEvolutionary BiologyMicrobialGeneticsSignal transductionGenomicMicrobiologyAcquired immunityStructuralMethodsPathwaysApproachesProteomicsInteractionsProteinsImmune systemProteinNeuroscienceQuantitative description2019ChemistryDrug discoveryGenome biologyBacterialCellResearchLectureInteractionDiseases2018InsightsMedicineExperimentallySignaturesMulticellularContentStudySyntheticDynamicsPostdoctoralHigh-throughputExploration
Bioinformatics4
- The reporter system could be useful for validating ribozyme function in candidate sequences identified from bioinformatics. (biomedcentral.com)
- The current research aims to identify shared molecular gene signatures and pathways that affirm the epidemiological association of T2DM and TB and afford clues on mechanistic basis of their association through integrative systems biology and bioinformatics approaches. (springeropen.com)
- A suggested MSc student project in bioinformatics potentially comprising also biochemistry and molecular microbiology studies. (lu.se)
- With the help of various forms of mass spectrometry, synchrotron radiation, protein production & labelling, and bioinformatics, our facilities provide the opportunity to study protein structure and dynamics, molecular probes and drug design. (lu.se)
Mechanisms9
- The focus of CeMBioS research group is to study the cellular, molecular, and genomic mechanisms which occur in the cells as an individual, as well as the building block of an organism including to the structure and function of the process underlying a biological system. (ui.ac.id)
- Perform in vitro experiments to study the molecular mechanisms regulated by nanoparticles. (systemsmedicine.net)
- Students look at the evolutionary ecology of mechanisms used by immune systems to recognize and kill parasites, finding similarities across animal taxa. (princeton.edu)
- Daphnia is a versatile model system to investigate fundamental mechanisms of inheritance and development, cellular function, physiological systems, immunity response, disease, macromolecular structure/function relationships and the genetic basis of complex phenotypic traits. (biomedcentral.com)
- Aggressive tumors typically demonstrate a high glycolytic rate, which results in resistance to radiation therapy and cancer progression via several molecular and physiologic mechanisms. (springer.com)
- Intriguingly, many of these mechanisms utilize the same molecular pathways that are altered through calorie and/or carbohydrate restriction. (springer.com)
- Perhaps, the association between TB and T2DM was the oldest to be identified, but the molecular mechanisms from the immunological point of view behind this comorbidity have only been explored recently [ 5 , 6 ]. (springeropen.com)
- My group develops computational systems biology approaches to tackle a major problem in medicine: to reveal the molecular mechanisms underlying the basis of complex disease. (tau.ac.il)
- A detailed understanding of the molecular details of interactions between nanoparticle s and biological nano-machinery - macromolecules, membranes, and intracellular organelles - is crucial for obtaining adequate information on mechanisms of action of nanomaterial s as well as a perspective on the long term effects of these materials and their possible toxicological outcomes. (cdc.gov)
Biochemistry5
- Important concepts and elements of molecular biology, biochemistry, genetics, and cell biology, are examined in an experimental context. (princeton.edu)
- In this course, we will cover subject matter in biochemistry, organic chemistry and structural biology. (columbia.edu)
- The course is intended to provide a foundation of structural biology, bio-organic chemistry and biochemistry and to expose students to some emerging areas of research. (columbia.edu)
- This course contains mainly molecular biology, biochemistry & genetic content, is based on reading research articles and requires writing a research proposal. (columbia.edu)
- Professor Torimiro is presently Associate Professor of Molecular Biology and Coordinator of Laboratories in the Chantal Biya International Reference Centre for Research on the Prevention and Management of HIV/AIDS, and Chair of the Department of Biochemistry in the Faculty of Medicine and Biomedical Sciences, University of Yaoundé. (who.int)
Computational10
- Computational approaches are keys for predictions of the molecular events involved in such cascades. (univr.it)
- In other words, computational systems biology needs to be paralleled by a quantitative description at the molecular level. (univr.it)
- Our group uses computational approaches to analyze the vast amount of molecular sequence data this produces. (uzh.ch)
- Dr. Zoe Cournia (female) is a Researcher - Assistant Professor level at the Biomedical Research Foundation, Academy of Athens, where she works on anticancer drug design, design of drug delivery systems and biomolecular modeling using computational techniques. (prace-ri.eu)
- Computational design tools for synthetic biology. (deepdyve.com)
- Computational approaches for variant prioritization include machine learning methods utilizing a large number of features, including molecular information, interaction networks, or phenotypes. (plos.org)
- Advances in Computational Biology / Bioinfo4Women. (mpg.de)
- Journal of computational biology : a journal of computational molecular cell biology 2010, 17(8):1051-1065. (tau.ac.il)
- This review focuses on the use of structure-based computational molecular modeling as a tool to understand and to predict the interactions between nanomaterial s and nano-biosystems. (cdc.gov)
- Supervised learning with decision tree-based methods in computational and systems biology. (bvsalud.org)
Evolutionary Biology1
Microbial3
- Molecular Systems Biology is a peer-reviewed open-access scientific journal covering systems biology at the molecular level (examples include: genomics, proteomics, metabolomics, microbial systems, the integration of cell signaling and regulatory networks), synthetic biology, and systems medicine. (wikipedia.org)
- This conference explores the application of emerging microbial and molecular tools to help resolve challenges faced by the industry. (microbe.com)
- Advanced knowledge of molecular genetics and microbial cell biology through case studies of model systems of molecular mycology (yeasts and filamentous fungi). (uni-goettingen.de)
Genetics2
- 2. Understanding major biological processes at the cellular and molecular level, through the application of methods drawn from structure, function, and genetics. (ui.ac.id)
- Prerequisites: genetics or molecular biology. (columbia.edu)
Signal transduction1
- Systems Biology Ireland (SBI), UCD School of Medicine , is looking for a postdoctoral research fellow with excellent knowledge concerning molecular biology and the use of Mass spectrometry-based proteomics for the study of signal transduction. (systemsmedicine.net)
Genomic3
- 3. Supporting advanced research within the cellular, molecular, and genomic area in the field of biodiversity conservation and prospection. (ui.ac.id)
- Our goals are to develop high-quality research, to train graduate students in cellular and molecular research, and to strengthen undergraduate education in the area of cellular, molecular and genomic mechanism. (ui.ac.id)
- Classical genetic techniques as well as molecular and genomic approaches will be discussed. (princeton.edu)
Microbiology1
- ISMOS is the largest event discussing microbiology and molecular biology in the oil and gas industry. (microbe.com)
Acquired immunity1
- The cellular and molecular basis of innate and acquired immunity will be discussed in detail. (princeton.edu)
Structural3
- Lectures on these topics will be integrated with introductory lectures on molecular and structural biology, thermodynamics, statistics, and machine learning. (columbia.edu)
- This four and a half-credit course will present an introduction to the Biophysical Chemistry and Structural Biology of proteins and nucleic acids. (columbia.edu)
- Molecular modeling in structural nano-toxicology: interactions of nano-particles with nano-machinery of cells. (cdc.gov)
Methods3
- The international team of researchers and industry representatives is collaborating in the development of molecular biological methods for locating deposits. (univie.ac.at)
- A very new and promising approach is based on molecular biological methods as they are designed to map changes in sediments above reservoirs where microorganisms are exposed to natural hydrocarbon leakage. (univie.ac.at)
- It is very useful to have well characterized systems for which one can test the validity and usefulness of the methods. (lu.se)
Pathways1
- However, major challenges of implementation lie at the point of integration into healthcare systems, including the modification of clinical pathways and a large knowledge gap in pharmacogenomics in the healthcare workforce. (cdc.gov)
Approaches4
- We emphasize the potential of these bio-inspired approaches in advancing electrocatalyst design and their relevance to molecular catalysis. (chimia.ch)
- However, experimental approaches have limitations when dealing with complex biological systems composed of multiple layers of regulation such as the transcriptional and post-transcriptional regulation by transcription factors (TFs) and miRNAs [ 2 ]. (hindawi.com)
- Most experimental approaches focus on the identification of miRNA targets and the investigation of physiological consequences when perturbing miRNA expressions but are unsuited to provide a system-level interpretation for observed phenomena. (hindawi.com)
- We will discuss approaches for discovering and optimizing chemical tools for measuring and perturbing biological systems. (columbia.edu)
Proteomics1
- Topics covered include various high-throughput genomics technologies (genome sequencing, DNA microarrays, proteomics), quantitative modeling of transcriptional and post-transcriptional regulatory networks, synthetic biology, and the world of RNA structure, dynamics, and function. (columbia.edu)
Interactions4
- We first construct a p21 regulatory network based on data from the literature and further expand it using algorithms that predict molecular interactions. (hindawi.com)
- a map is constructed that shows interactions among molecular entities (such as genes, proteins and RNAs), using information from literature and databases. (hindawi.com)
- The network combining putative targets of TF and miRNA regulation with experimentally proven molecular interactions was constructed and visualized. (hindawi.com)
- Our facilities provide the opportunity to study protein structure, molecular probes and drug design, system biology and molecular interactions in cells and tissues. (lu.se)
Proteins6
- Therefore, Ubiquilins are part of a quality control system for getting rid of mislocalised proteins. (cam.ac.uk)
- The course will cover basic molecular biology topics such as information storage and readout by DNA, RNA, and proteins. (princeton.edu)
- We will discuss the structure and function of both proteins and small molecules in biological systems. (columbia.edu)
- Topics covered will include high-throughput assay development, screening, chemical library creation, high-throughput chemistry, affinity purification of target proteins and target validation, protein microarrays, molecular evolution, protein engineering and synthetic biology. (columbia.edu)
- Unlocking the Mysteries of the Immune System: new Roles of complement proteins in Diabetes and Cancer. (lu.se)
- Below is a non-exhaustive list of in-house infrastructures that are categorized into three overarching themes: bio-imaging, proteins, genes & cells and other resources. (lu.se)
Immune system7
- A broad survey of the field of immunology and the mammalian immune system. (princeton.edu)
- Comprehensive and full set of notes (lectures + additional material) for Cell and Molecular Biology of the Immune System. (thinkswap.com)
- Interaction between the human host and its's microbiome is mediated via several axes of communication including the immune system, signalling and direct metabolic cross-talk that physiologically connect the gut with the brain, muscle and liver. (imperial.ac.uk)
- Overview of the Immune System The immune system distinguishes self from nonself and eliminates potentially harmful nonself molecules and cells from the body. (msdmanuals.com)
- The immune system also has the capacity to recognize and destroy. (msdmanuals.com)
- Cellular Components of the Immune System The immune system consists of cellular components and molecular components that work together to destroy antigens. (msdmanuals.com)
- See also Overview of the Immune System. (msdmanuals.com)
Protein4
- In this talk I will review current efforts at computationally characterizing the molecular determinants in the largest membrane-bound receptor family, the G-protein-coupled receptors (GPCRs). (univr.it)
- Thus, a major goal of cell biology is to discover the cell's protein quality control systems and determine how they work to keep cells healthy. (cam.ac.uk)
- Research by Manu Hegde's lab in the LMB's Cell Biology Division has found a new protein quality control pathway. (cam.ac.uk)
- Molecular neuroscience has largely focused on the functions of protein-coding genes, which account for less than 2% of our DNA. (lu.se)
Neuroscience1
- Lectures will give an overview at levels ranging from molecular signaling to cognitive science with a focus on the neuroscience of everyday life, from the general (love, memory, and personality) to the particular (jet lag, autism, and weight loss). (princeton.edu)
Quantitative description1
- This four-credit course will present a quantitative description of the molecular networks that underlie the myriad phenotypes of living cells, from yeast to human. (columbia.edu)
20191
- ACS Synthetic Biology 2019, 8 (7), 1498-1514. (ncl.ac.uk)
Chemistry3
- Background in Physics/Chemistry/Biology. (prace-ri.eu)
- The course is intended for advanced undergraduates as well as beginning graduate students in Biology, Chemistry, Physics, Engineering, and Computer Science. (columbia.edu)
- The course will be of interest to students at the interface between chemistry and biology, and students interested in medicine, academic chemical biology and drug discovery efforts. (columbia.edu)
Drug discovery1
- Building New Bridges between in Vitro and in Vivo in Early Drug Discovery: Where Molecular Modeling Meets Systems Biology. (ventustx.com)
Genome biology1
- This thematic series of companion papers constitutes the initial exploration of the genome biology of the waterflea (Daphnia) building on the first complete crustacean genome sequence. (biomedcentral.com)
Bacterial2
- For pulsed-field gel electrophoresis (PFGE), bacterial plugs were digested with restriction endonucleases Xba I and Spe I. Digests were subjected to gel electrophoresis using the Chef Mapper System (Bio-Rad Laboratories, Hercules, CA, USA) with a bacteriophage λ DNA ladder. (cdc.gov)
- The Molecular biology of bacterial virus systems / edited by G. Hobom and R. Rott. (who.int)
Cell3
- While completing original research, you will employ techniques used by cell and molecular biologists and developmental geneticists. (princeton.edu)
- We established a ribozyme reporter system in Escherichia coli in which a significant reduction of reporter activity is manifest when an active ribozyme sequence is fused to the reporter gene and the expression of a foreign Bacillus subtilis RNaseJ1 5′ exonuclease is induced from a chromosomally-integrated gene in the same cell. (biomedcentral.com)
- The functional enrichment and gene interaction network analysis emphasized the importance of cytokine/chemokine signalling, T cell receptor signalling route, NF-kappa B signalling pathway and Jak-STAT signalling system. (springeropen.com)
Research9
- 1. Conducting basic research in the biological system. (ui.ac.id)
- One of the world's leading research institutes, our scientists are working to advance understanding of biological processes at the molecular level - providing the knowledge needed to solve key problems in human health. (cam.ac.uk)
- Individuals who are interested in an early research experience that substitutes for MOL350-Laboratory in Molecular Biology can enroll in this course. (princeton.edu)
- Taught by research scientists active in various of systems biology, the course is highly interdisciplinary and rooted in recent research, with a soft focus on cancer. (columbia.edu)
- The course is intended to provide a foundation needed for advanced chemical biology research, i.e. the creation and use of chemical probes of biological processes and macromolecular function. (columbia.edu)
- Earlier research has found specific molecular markers linked to T2DM and TB, but, despite their importance, only offered a limited understanding of the genesis of this comorbidity. (springeropen.com)
- Important: If you meet all of the eligibility requirements below AND are a US citizen or US permanent resident belonging to a minority group recognized as underrepresented in the sciences by the NIH please be aware that you qualify to apply for a Minority Access to Research Careers (MARC) travel award through the Federation of American Societies for Experimental Biology (FASEB). (iscb.org)
- Source code developed for this project is available at https://github.com/bio-ontology-research-group/phenomenet-vp , and analysis results at http://www.cbrc.kaust.edu.sa/onto/pvp/ . (plos.org)
- Experience: Dr. Bruckner is an environmental toxicologist whose research areas include development of in vitro testing systems for hepatorenal toxins, comparison of the relative pharmacokinetics and toxicity of inhaled and ingested organics, and investigation of the toxicity of halogenated hydrocarbons. (cdc.gov)
Lecture1
- This lecture and laboratory course will acquaint non-biology majors with the theory and practice of modern molecular biology, focusing on topics of current interest to society. (princeton.edu)
Interaction1
- depending on the biological problem investigated and experimental data available, the interaction map can be translated into a detailed mechanistic model that can simulate the temporal evolution of molecular entities. (hindawi.com)
Diseases2
- The Systems Medicine Web Hub supports researchers with the communication of their efforts to improve the diagnosis, prognosis and therapy of diseases. (systemsmedicine.net)
- Recent studies in other diseases suggest that a classification which includes molecular information could lead to more accurate diagnoses and prediction of treatment response. (cdc.gov)
20181
- Journal of Molecular Evolution 2018, 86 (6), 395-403. (ncl.ac.uk)
Insights2
- This perspective article delves into the realm of bio-inspired catalysis, highlighting the valuable insights gleaned from enzymatic systems for the design of advanced electrocatalysts. (chimia.ch)
- we hypothesized that profiles of airway fluid cytokines that represent major effectors molecules of leukocytic inflammation could provide insights for developing a new molecular-based classification of asthma. (cdc.gov)
Medicine3
- Systemsmedicine.net is the home of systems medicine in the Internet. (systemsmedicine.net)
- Our investigation used a network medicine method to find possible T2DM-TB molecular mediators. (springeropen.com)
- School of Cellular and Molecular Medicine, Bristol, United Kingdom. (bvsalud.org)
Experimentally1
- On the next level carefully selected model systems are studied experimentally. (lu.se)
Signatures1
- Michelson, Seth 2012-01-04 00:00:00 [Many different OMICs/HTS techniques now allow huge amounts of molecular signatures to be collected and then analysed further by system tools. (deepdyve.com)
Multicellular1
- In silico multicellular systems biology and minimal genomes. (deepdyve.com)
Content1
- Advanced Molecular Detection Clips content is selected solely based on its potential interest to readers. (cdc.gov)
Study3
- Ultimately, therefore, understanding of these events, requires the integration of detailed molecular information into the study of biological complexes. (univr.it)
- Develop your entrepreneurial skills while you study molecular biology to enhance your employability. (manchester.ac.uk)
- The application of the systems biology approach to the analysis of a gene regulatory network is demonstrated with a case study of the regulation of p21 by multiple miRNAs [ 4 ]. (hindawi.com)
Synthetic3
- Chemogenomics, morphogenics and synthetic biology are only in the early stages of development, but may contribute to target identification. (deepdyve.com)
- Mısırlı G, Taylor R, Goñi-Moreno A, McLaughlin JA, Myers C, Gennari JH, Lord P, Wipat A. SBOL-OWL: An Ontological Approach for Formal and Semantic Representation of Synthetic Biology Information . (ncl.ac.uk)
- ACS Synthetic Biology 2016, 5 (10), 1086-1097. (ncl.ac.uk)
Dynamics2
- The purpose of this course is to present to existing and potential users of Molecular Dynamics packages the method, the necessary steps for a successful simulation, common practices, common mistakes. (prace-ri.eu)
- NAMD, GROMACS, LAMMPS, CP2K), for molecular modelling and molecular dynamics simulations, how to create configuration files based on their needs, tuning the models, how to efficiently use the resources based on the simulation details, avoid common mistakes. (prace-ri.eu)
Postdoctoral1
- and training of health workers and supervising postdoctoral fellows, specifically in molecular biology. (who.int)
High-throughput1
- Advances in high-throughput experimental biology have greatly furthered our knowledge and made it possible to interrogate cellular processes in a systematic manner. (nature.com)
Exploration3
- Some of the most exciting applications are in the field of biomedicine - for theranostics (for combined diagnostic and therapeutic purposes) as well as for exploration of biological systems. (cdc.gov)
- The intriguing realm of porifera, known as sponges, beckons exploration in molecular biology. (lu.se)
- The dynamic world of porifera, commonly known as sponges, presents a captivating avenue for exploration within molecular biology. (lu.se)