• In Situ Characterization of Mixtures of Linear and Branched Hydrocarbons Confined within Porous Media Using 2D DQF-COSY NMR Spectroscopy. (acs.org)
  • The topics studied in this area include structure and bonding theories, reaction mechanisms and characterisation methods (NMR and molecular spectroscopy). (lu.se)
  • The research at the Chemistry Department in Lund will focus on material characterization through a combination of spectroscopy, microscopy and computational chemistry. (lu.se)
  • reported the dissemination of MDR OXA-23-producing A. baumannii clones throughout multiple cities in China, but little is known about the molecular mechanisms of resistance to carbapenems in western China. (frontiersin.org)
  • Understanding the structure and function of ABCA4 is important to uncovering the underlying mechanisms and facilitating therapy development. (elifesciences.org)
  • We are trying to understand the molecular mechanisms of mechanochemical coupling. (warwick.ac.uk)
  • The research themes rank around molecular mechanisms matrix proteins and fibers exert in disorders affecting blood vessels, bone, skin and adipose tissue. (mcgill.ca)
  • Considerable emphasis on modern theoretical interpretation of structure and of reaction mechanisms. (beloit.edu)
  • Applied methods range from protein chromatography to spectroscopic analysis of protein structure and mechanisms of enzyme functions. (fraunhofer.de)
  • Thus, the aim of this work is to carry out a review of the literature on the role of bacterial endotoxin in the etiology of periapical lesions, its mechanism of action, and to elucidate molecular mechanisms involved in endotoxin's recognition by the immune system and cell activation. (bvsalud.org)
  • Therefore, the objective of this study is to carry out a review of the literature on the role of bacterial endotoxin in the etiology of periapical lesions, as well as to elucidate molecular mechanisms involved in its recognition by the immune system and in cell activation. (bvsalud.org)
  • This includes a wide range of complementary techniques and expertise in molecular biology and cellular signalling, glycobiology , and structural biology and is underpinned by a wide range of national and international collaborations and access to world-leading Central Facilities including Institute Laue Langevin ( Life Sciences Group and Deuteration Laboratory ), Diamond Light Source and Harwell Campus , Liverpool Technology Directorate and Midlands Innovation . (keele.ac.uk)
  • Investigating and understanding biology through molecular characterization and structure. (bnl.gov)
  • I did my PhD work at Nottingham and my postdoctoral training as an EMBO Fellow with Vic Small at the IMB in Salzburg and as an MDA Fellow with John Kendrick Jones at the MRC Laboratory of Molecular Biology in Cambridge, working on the myosin II mechanism. (warwick.ac.uk)
  • Together with the biophysical characterization of the Tbx5 mutants and ITC binding data, both crystal structures were published in Journal of Molecular Biology. (europa.eu)
  • I teach mainly plant and molecular biology at different levels. (lu.se)
  • The education we offer in biology and molecular biology at our department is among the best in Sweden as well as being of a high standard internationally. (lu.se)
  • This thesis describes the design, synthesis and characterization of supramolecular halogen-bonded capsules and cages from multivalent ligands. (jyu.fi)
  • 2013, Graduate Research, Synthesis and Characterization of Novel Molecular Organic Materials for Clean Energy Applications. (cmich.edu)
  • 37 (3), 271-283 (1995) PUBMED 8533462 REFERENCE 2 (bases 1 to 3435) AUTHORS Green,S.M. TITLE Direct Submission JOURNAL Submitted (30-JAN-1995) S.M. Green, University of Southampton, Molecular Microbiology, Level C, South Block, Southampton General Hospital, Southampton SO16 6YD, UK FEATURES Location/Qualifiers source 1. (cdc.gov)
  • Fast accurate predictions of 1 H NMR spectra of organic compounds play an important role in structure validation, automatic structure elucidation, or calibration of chemometric methods. (acs.org)
  • Structure-property relationships in PVC-lubricant compounds. (sun.ac.za)
  • The course has a molecular perspective and a further aim to enable students to develop their ability to describe the structure and reactivity of coordination compounds and their applications in organometallic chemistry and homogeneous catalysis, and the significance of metals in biological systems. (lu.se)
  • Antigenic characterization is a laboratory testing process that flu scientists use to measure how flu viruses are evolving to evade human immunity. (cdc.gov)
  • Comparison between the DNA-free Tbx5 structure to the one bound a natural single T-box binding element (previously solved in the laboratory of the scientist in charge) revealed insight into the interaction mechanism to its target DNA. (europa.eu)
  • 7-14 The ability of narrow polydispersity rrP3ATs synthesized in McCullough laboratory to form well-defined fibrillar structures enabled us to use GISAXS patterns to recognize another particularly important aspect of molecular and nanoscale organization of polythiophene-like polymers: their intrinsic molecular and nanoscale porosity. (cmu.edu)
  • Laboratory: basic techniques and synthetic procedures and modern spectroscopic methods of structure determination. (beloit.edu)
  • The group is also actively involved in the application and development of proximal probe techniques, especially atomic force microscopy (AFM), to structure-property studies of materials and to manipulation of matter at the nanoscale level. (cmu.edu)
  • We also work to develop structure‐function relationships by correlating performance metrics to high energy x‐ray characterization and microscopy data. (nist.gov)
  • The reduction of molecular complexity in the individual DOM fractions attenuates intermolecular interactions and substantially increases the disposable resolution of any structure selective characterization. (awi.de)
  • Comparative mass analysis showed that fractionation of SR DOM was governed by multiple molecular interactions depending on O/C ratio, molecular weight and aromaticity. (awi.de)
  • The goal of the new project is to make efficient solar cells from molecular semiconductors through improved processing technology and better understanding of how the fundamental molecular interactions govern the structure in these functional materials. (lu.se)
  • Analytical applications and characterization of nanomaterials. (muni.cz)
  • Multidimensional analytical approach for the characterization of complex ethylene propylene copolymers. (sun.ac.za)
  • Our findings elucidate the complementary nature of AHPO and ToF-SIMS during chemical characterization of eumelanin traces in fossilized organismal remains. (lu.se)
  • For these reasons, fore not fully elucidate the molecular origin of the ob- most mechanistic studies have been carried out on model served relaxation effects. (lu.se)
  • We have recently shown [1] that the integration of solid-state NMR with multi-scale molecular dynamics simulations gives access to high-resolution structures of supramolecular peptide-based drug vectors (Figure 2). (uu.nl)
  • First, the sequences carrying point mutations are modeled on a given template structure, and subsequently, molecular dynamics simulations are carried out for 10 ns. (hindawi.com)
  • The limits of current methods is the incorporation of molecular dynamics simulations into the multi-objective optimization. (hindawi.com)
  • Due to the fact that molecular dynamics simulations are very expensive regarding computational time, new fitness functions have to be introduced without loosing predictive power. (hindawi.com)
  • It was corroborated by means of molecular dynamics simulations. (curefa.org)
  • To obtain a molecular understanding of IDPs, a combined approach of experiments and simulations is useful. (lu.se)
  • Characterization of the ligand was performed by FT-IR, 1 H NMR, 13 C NMR, UV-Vis, elemental analysis and single crystal X-ray diffraction. (scirp.org)
  • Gharamaleki, J. , Akbari, F. , Karbalaei, A. , Ghiassi, K. and Olmstead, M. (2016) Synthesis, Characterization and Crystal Structure of a New Schiff Base Ligand from a Bis(Thiazoline) Template and Hydrolytic Cleavage of the Imine Bond Induced by a Co(II) Cation. (scirp.org)
  • Broadly used in modern drug design, molecular docking methods explore the ligand conformations adopted within the binding sites of macromolecular targets. (mdpi.com)
  • We develop nanoparticle materials for specific electrochemical or chemical reactions through variation of bimetallic composition, morphological structure, extent of oxide/oxyhydroxide phases, and ligand concentration and molecular structure. (nist.gov)
  • Understanding on a molecular level the underlying regulatory pathways and the synergistic action of transcription factors is of broad interest for cardiovascular biologist, as it opens the perspective to influence cardiac growth and stimulate cardiac regeneration. (europa.eu)
  • 3,8-9 In fact, there is a great interest in the understanding of its structure and its mechanism of action, particularly of the molecular pathways involved in its recognition and cellular signaling, 10-15 as well as the forms of its inactivation 3,16 . (bvsalud.org)
  • Neither the molecular mechanism of this activity nor its physiological importance are known. (nature.com)
  • Despite decades of clinical, biochemical, and animal model studies, the molecular mechanism of ABCA4 is unknown. (elifesciences.org)
  • Whereas the phenomenology of water-1H tions of bulk water (14), and similar ideas regarding long- relaxation in tissue is well documented (1-3), the under- range ordering and slowing down of water motions have lying molecular mechanism remains controversial (4 -9). (lu.se)
  • The unit's competence also encompasses the isolation and characterization of antibodies aiming at developing protein drugs as well as their semi-preparative extraction. (fraunhofer.de)
  • Molecular structure and characterization of bovine heart protein kinase. (elsevierpure.com)
  • However, molecular weight is also important due to potential steric incompatibilities within protein cores. (hindawi.com)
  • The structure determination of this protein will be helpful to improve the stability of the enzymes by mutational studies and thus modulate the function of these important enzymes. (omicsonline.org)
  • The Protein and Drug Biochemistry Unit's expertise lies in the purification of bacterial, plant and animal proteins, target proteins and their chemical and enzymological characterization. (fraunhofer.de)
  • First nationwide study regarding ceftriaxone resistance and molecular epidemiology of Neisseria gonorrhoeae in China. (cdc.gov)
  • In this study, we provide the molecular characterization and epidemiology for 12 NDM-1 positive clinical isolates. (who.int)
  • In addition, we aim to teach you the fundamentals and application possibilities of different spectroscopic methods available for the determination and characterization of molecular structures. (ulb.be)
  • The remarkable results on yield, process, development of DHPs, anti‐proliferative activity, structure determination and single crystal study of DHPs discussed in this article. (researchgate.net)
  • Control over the nanoscale morphology opens the way to control of electronic structure by restricting the spatial extent of nanographitic domains, and, what is of particular importance, assuring their edge-on orientation with respect to the pore walls , thus guaranteeing their accessibility. (cmu.edu)
  • Biochemical characterization of ABCA4. (elifesciences.org)
  • The studies involve biochemical structure/function-related studies of enzymes with a biotechnological potential. (lu.se)
  • structure-transport properties relationships in semiconducting polymers and organic photovoltaics, and nanostructured polymer networks. (cmu.edu)
  • Antigenic characterization" refers to the analysis of different viruses' antigenic properties to help determine their similarity. (cdc.gov)
  • Antigenic characterization of H3N2 viruses has become increasingly challenging in recent years. (cdc.gov)
  • CDC's flu scientists developed HINT to work around these problems, and therefore, to improve antigenic characterization of H3N2 viruses. (cdc.gov)
  • As a result, HINT speeds up antigenic characterization and potentially avoids introducing new mutations or changes to the viruses being characterized. (cdc.gov)
  • This study's researchers used HINT in combination with new genome sequencing technologies and practices to identify particular evolutionary changes in the HA surface antigen of circulating H3N2 viruses that allow these viruses to evade the human immune response at the molecular level. (cdc.gov)
  • Molecular characterization of pig epidemic diarrhoea viruses isolated in Japan from 2013 to 2014. (cdc.gov)
  • REFERENCE 1 (bases 1 to 3435) AUTHORS Green,S.M., Lambden,P.R., Caul,E.O., Ashley,C.R. and Clarke,I.N. TITLE Capsid diversity in small round-structured viruses: molecular characterization of an antigenically distinct human enteric calicivirus JOURNAL Virus Res. (cdc.gov)
  • Deciphering the molecular codes of dissolved organic matter (DOM) improves our understanding of its role in the global element cycles and its active involvement in ecosystem services. (awi.de)
  • Revealing the nano- to mesoscale structure and complex dynamics of heterogeneous systems under in situ conditions. (bnl.gov)
  • In the proposed master project, the student will investigate the supramolecular structure and dynamics of a peptide-based drug vector for gene therapy. (uu.nl)
  • In this area we are collaborating with Matyjaszewski's group on exploring the impact of controlled heterogeneity on the structure and dynamics of polymer network systems. (cmu.edu)
  • Pharmaceutical research has successfully incorporated a wealth of molecular modeling methods, within a variety of drug discovery programs, to study complex biological and chemical systems. (mdpi.com)
  • I also want to continue with a project aiming at analysing and characterization of the biological function and molecular structure of one of the glucanase group of the PR-proteins. (lu.se)
  • In this study, we investigated the epidemiological and molecular differences of CRAB and the threatening factors for contributing to increased CRAB infections at a hospital in western China. (frontiersin.org)
  • Molecular and epidemiological study of enterovirus D68 in Taiwan. (cdc.gov)
  • Synthesis of high solids coatings based on molecular brushes. (sun.ac.za)
  • However, systematic spectral changes upon maturation reduced these dissimilarities, indicating that intense heat and pressure treatment leads to the formation of a com-mon, partially degraded, eumelanin molecular structure. (lu.se)
  • Various types of β-lactam antibiotics, for example carbapenems, contain β-lactam rings in their structures and can be inactivated by β-lactamase enzymes. (frontiersin.org)
  • Xylan, major polysaccharide of hemicellulose, requires the action of several hydrolytic enzymes due to its heterogeneity and the complex chemical structure. (omicsonline.org)
  • His research interest includes molecular characterization, structure-function relationship of enzymes that is useful for industrial purpose. (omicsonline.org)
  • Yet, peptide assemblies are often not amenable to most high-resolution methods and hence poorly understood at the molecular level. (uu.nl)
  • Successful investigation in structure/response relationships requires the student to become familiar with statistical methods of analysis. (esf.edu)
  • An Overview of Physical Adsorption Methods for the Characterization of Finely Divided and Porous Materials and Their Application to Fluid Cracking Catalysts. (micromeritics.com)
  • Each of our beamlines offers unique research tools to reveal the electronic, chemical, and atomic structure of materials. (bnl.gov)
  • Characterizing and modeling the atomic structure and chemistry of complex materials during synthesis, processing, and energy conversion. (bnl.gov)
  • A total of 110 clinical isolates of A. baumannii , collected in a recent 2-year period, were tested for carbapenem antibiotic susceptibility, followed by a molecular analysis of carbapenemase genes. (frontiersin.org)
  • The optimization was guided by directed evolution based on hydrophobicity scores, molecular weight, and secondary structure predictions. (hindawi.com)
  • The subsequent structure-activity-analysis as well as structure-based molecular optimization complement the unit's portfolio. (fraunhofer.de)
  • These structures provide a molecular basis to understand many disease-causing mutations and a rational guide for new experiments to uncover how ABCA4 recruits, flips, and releases retinoids. (elifesciences.org)
  • Antimicrobial resistance and population structure of Staphylococcus aureus recovered from pigs farms. (cdc.gov)
  • 137, 7775, The supramolecular organization of a peptide based nanocarrier at high molecular detail. (uu.nl)
  • Cry protoxins have a high molecular weight (70-140 kDa) and are soluble at alkaline pH. (scielo.br)
  • Subsequent more plicated by incomplete knowledge about the chemical systematic studies attributed the relaxation enhancement composition and supramolecular structure of most tissues. (lu.se)
  • In the crystal, O-H⋯O hydrogen bonds between the components lead to the formation of a three-dimensional supra-molecular framework. (iucr.org)
  • The crystal structure of the title compound comprises polymeric chains formed by two independent copper(II) polyhedra, [CuN 2 O 2 ] and [CuN 4 O 2 ], which are linked by sulfate anions and stabilized by extended hydrogen-bonding, C-H⋯π and π-π inter-actions. (iucr.org)
  • An influenza virus' surface proteins: hemagglutinin (HA) and neuraminidase (NA) are "antigens," which are molecular structures that trigger an immune response in an infected host. (cdc.gov)
  • Given the intimate relationship between a protein's structure and function, a way to design proteins with targeted properties is to start from a desired structure and find sequences able to fold into it, imposing additional constraints in the process [ 1 ]. (hindawi.com)
  • Thus more than 100 crystal structures containing this aforementioned fragment are deposited with the CCDC [6]. (researchgate.net)
  • In contrast to their rigid inorganic cousins, molecular metal halides exhibit mechanical flexibility and low dielectric constants, providing an avenue for structural engineering united with strong piezoelectric response. (nature.com)
  • This enables piezoelectric energy harvesting in EDABCO-CuCl 4 @PVDF (polyvinylidene fluoride) composite film with a peak power density of 43 µW/cm 2 (at 50 kPa), the highest value reported for mechanical energy harvesters based on heavy-metal-free molecular piezoelectric. (nature.com)
  • Reports have shown that plastic ferroelectric crystals with spherical molecular structures exhibit prominent piezoelectricity due to the mechanical softness of their lattices 12 . (nature.com)
  • High-resolution transmission electron images and selected area electron diffraction patterns reveal a nanodomain structure. (rsc.org)
  • In contrast, Cry toxins have moderate molecular weights (40-70 kDa) and are resistant to proteolysis and stable at extreme pH (2). (scielo.br)
  • In 1991 I left MRC-LMB to set up a lab at the Marie Curie Research Institute to work on kinesin molecular motors, which were then newly-discovered. (warwick.ac.uk)
  • However, plastic crystals tend to crystallize in highly symmetric cubic crystal systems due to the disordered orientation of spherical molecules, making it challenging to obtain non-centrosymmetric structures 13 . (nature.com)
  • This study demonstrates comprehensive characterization of DOM by an initial polarity-based stepwise solid phase extraction (SPE) with single methanol elution of the cartridges, but separate collection of equal aliquots of eluate. (awi.de)
  • Analysis of these regions will continue with the addition of molecular line data, which will allow us to study the densest regions of the clumps in more detail. (aanda.org)
  • Characterization of Binders Used in the Fabrication of Graphite Bodies. (ntis.gov)
  • Our work is highly interdisciplinary, and spans the range from molecular design, synthesis, through structure-properties studies to fabrication and characterization of devices. (cmu.edu)
  • 8. von Schantz L, Schagerlöf H, Nordberg-Karlsson E, Ohlin M. ( 2014 ) Characterization of the substitution pattern of cellulose derivatives using carbohydrate-binding modules. (lu.se)
  • SILCAR showed the highest resistance, suggesting a more rigid structure. (curefa.org)
  • This structure (2) was also confirmed by single crystal X-ray analysis. (scirp.org)
  • how-ever, confident identification and characterization of these natural pigments remain challenging due to loss of chemical signatures during diagenesis. (lu.se)
  • Our results show that AHPO is sensitive to changes in the melanin molecular structure already during mild heat and pressure treatment (resulting, e.g., in increased C-C cross-linking), whereas harsh maturation leads to extensive loss of eumelanin-specific chemical markers. (lu.se)
  • AaCaMKs Positively Regulate Development, Infection Structure Differentiation and Pathogenicity in Alternaria alternata , Causal Agent of Pear Black Spot. (bvsalud.org)
  • Molecular Characterization of Phospholipase C in Infection Structure Differentiation Induced by Pear Fruit Surface Signals, Stress Responses, Secondary Metabolism, and Virulence of Alternaria alternata . (bvsalud.org)
  • When I eventually returned to Lund University, I started to get interested in the interplay between microorganisms and plants on a molecular level. (lu.se)