• Several studies have focused on the evolution of HIV-1, but there is little information to link sequence similarities and evolutionary histories of HIV-1 to the epidemiological information of the infected individual. (washington.edu)
  • Bioinformatics: Volume 1: Data, Sequence Analysis and Evolution. (koeltz.com)
  • Examines a selection of methods involving the generation and organization of data, including sequence data, RNA and protein structures, microarray expression data and functional annotations, methods for discovering the functional components of genomes, whether they be genes, alternative splice sites, non-coding RNAs or regulatory motifs, and several of the most interesting methods in phylogenetics and evolution. (koeltz.com)
  • SPIA pathway analysis indicates a core set of pathways demonstrating altered expression across the TNBC sub-types and the identification of molecular targets within each subtype is ongoing. (aacrjournals.org)
  • ITHACA, N.Y.--( BUSINESS WIRE )-- Rheonix Inc. , a developer of fully automated molecular testing solutions, will highlight its Encompass Optimum ™ workstation at the Association for Molecular Pathology (AMP) Annual Meeting Nov. 10-12 in Charlotte, North Carolina. (businesswire.com)
  • Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of necessary materials and reagents, step-by-step, readily reproducible protocols, and key tips on troubleshooting and avoiding known pitfalls. (abebooks.com)
  • Using tree construction, MDS, and newly developed likelihood assignment methods on the original 100 samples we sequenced, and also on a set of blinded samples, we were able to predict demographic/risk group membership at a rate statistically better than by chance alone. (washington.edu)
  • 2008. (Methods in Molecular Biology, Volume 452). (koeltz.com)
  • When sequenced on the Illumina platform, the resulting libraries yielded NGS sequence data indistinguishable from the labor-intensive methods previously employed by the facility. (businesswire.com)
  • These membranes are then probed as many times as there are types of tags in the original pools, producing, in each cycle of probing, autoradiographs similar to those from standard DNA sequencing methods. (harvard.edu)
  • Third, the molecular laboratory is challenged to monitor its sequencing processes for nonrandom process variation and other quality metrics. (elsevier.com)
  • It is shown that more power can be achieved by increasing the length of sequence determined than by increasing the number of genomes sampled for the same total work. (genetics.org)
  • Interpreting relationships of human immunodeficiency virus type 1 (HIV-1) sequences can be challenging because of their rapidly evolving genomes, but it may also lead to a better understanding of the underlying biology. (washington.edu)
  • We utilize DNA sequence data from the nuclear, chloroplast, and mitochondrial genomes to infer historical processes of biodiversification. (duke.edu)
  • The ability to infer relationships between groups of sequences, either by searching for their evolutionary history or by comparing their sequence similarity, can be a crucial step in hypothesis testing. (washington.edu)
  • The detection of linkage disequilibrium in molecular sequence data. (genetics.org)
  • Detection of copy number variants (CNV) within WES data have become possible through the development of various algorithms and software programs that utilize read-depth as the main information. (biomedcentral.com)
  • Here, we evaluated three representative and popular read-depth based CNV detection programs: the eXome-Hidden Markov Model (XHMM), the Copy Number Inference From Exome Reads (CoNIFER), and CNVnator using clinical grade WES data. (biomedcentral.com)
  • once the raw specimen is loaded, the fully automated, high-efficiency system performs all sample preparation and molecular detection on the workstation. (businesswire.com)
  • These included techniques for compressing of data generated, Chromatin Immunoprecipitation (ChIP-seq), and various approaches for the identification of sequence variants. (abebooks.com)
  • Lina B , Bouscambert M , Enouf V , Rousset D , Valette M , van der Werf S . S-OtrH3N2 viruses: use of sequence data for description of the molecular characteristics of the viruses and their relatedness to previously circulating H3N2 human viruses. (eurosurveillance.org)
  • Such predictions of demographic epidemiology based on sequence information may become valuable in assigning different treatment regimens to infected individuals. (washington.edu)
  • That method identified statistically significant correlations between the viral sequences and the risk factors of men who engage in sex with men and individuals who engage in sex with injection drug users or use injection drugs themselves. (washington.edu)
  • Rheonix will present data from a user-defined assay for sexually transmitted infections (STIs), as well as data that demonstrates new capabilities of its system in next-generation sequencing (NGS) library preparation. (businesswire.com)
  • Bayesian hypothesis testing of four-taxon topologies using molecular sequence data. (semanticscholar.org)
  • The aim of this work is to organize data in a way that allows researchers to access existing information and to submit new entries as they are produced. (must.edu.eg)
  • For TNBC patients who fail standard chemotherapy, there are a lack of novel drug therapies, given the absence of well-defined molecular targets. (aacrjournals.org)
  • Dr. Montagna will present data showing use of the Rheonix Chemistry and Reagent Device (CARD ® ) technology in a user-defined molecular assay that simultaneously detects 20 targets for STIs. (businesswire.com)
  • As a result, clinicians often struggle to find historical gene sequence results on a series of oncology patients within the EHR that might influence the care of the current patient. (elsevier.com)
  • and Boosting won the best accuracy on 4 data sets (i.e., hepatitis, lymph, sick and splice). (uci.edu)
  • Johansson, Ulf S. & Ericson, Per G. P. (2003): Molecular support for a sister group relationship between Pici and Galbulae (Piciformes sensu Wetmore 1960). (wikipedia.org)
  • Paired CMA and WES data were acquired for 45 samples. (biomedcentral.com)
  • The increasing demand for DNA sequences can be met by replacement of each DNA sample in a device with a mixture of N samples so that the normal throughput is increased by a factor of N. Such a method is described. (harvard.edu)
  • The collections represent a central resource for bryological research at Duke, and we are actively integrating molecular investigations with field work and collections- based approaches. (duke.edu)
  • The Rheonix platform successfully reduced the time to prepare DNA libraries for sequencing on the Illumina MiSeq platform from 1.5 - 2.5 days to only three hours of hands-free effort. (businesswire.com)
  • Study record managers: refer to the Data Element Definitions if submitting registration or results information. (clinicaltrials.gov)