Molecular population chlamydia trachomatis. Medical search. Frequent questions

Objective To determine the prevalence of Chlamydia trachomatis (CT) and Neisseria gonorrhoeae (NG) in the homeless population in Medellín, Colombia, using molecular diagnostic methods. (researchgate.net)
The aim of this study was to describe the most common cytological features in cervical pap smears of patients with Chlamydia trachomatis , Neisseria gonorrhoeae , Mycoplasma genitalium , Trichomonas vaginalis , Mycoplasma hominis , Ureaplasma urealyticum , and Ureaplasma parvum detected by multiplex PCR. (hindawi.com)
Ureaplasma parvum 14.9%, Chlamydia trachomatis 10.6%, Trichomonas vaginalis 10.6%, Mycoplasma hominis 8.5%, Ureaplasma urealyticum 4.2%, Neisseria gonorrhoeae 2.1%, and Mycoplasma genitalium (0). (hindawi.com)
OTCQX: RHHBY) announced today that the U.S. Food and Drug Administration (FDA) has provided 510(k) clearance to the cobas® CT/NG Test for the detection of Chlamydia trachomatis (CT) and Neisseria gonorrhoeae (NG) infections in both symptomatic and asymptomatic patients from male urine and self -collected vaginal swabs. (news-medical.net)
This study aimed to estimate the prevalence of Neisseria gonorrhoeae and Chlamydia trachomatis infections and to assess the therapeutic management of vaginal/urethral discharge and dysuria in patients with human immunodeficiency virus in Luanda, Angola, taking into account World Health Organization recommendations for sexually transmitted infection syndromic management. (unl.pt)
Objectives: This study assessed feasibility of using the Xpert CT/NG test to identify prevalent Chlamydia trachomatis (CT) and Neisseria gonorrhea (NG) infections among STD clinic attendees and their sexual partners and tested for antimicrobial resistance for N. gonorrhea. (bvsalud.org)
My patient had a positive Neisseria gonorrhoeae urine nucleic acid amplification test (NAAT), but a negative Chlamydia trachomatis NAAT. (smartsexresource.com)

Penetrates prostate well and is effective against N gonorrhea and C trachomatis . (medscape.com)
A polymerase chain reaction (PCR)-based multiplex dual probe assay, the test for chlamydia and gonorrhea offers excellent sensitivity and high specificity and runs on the automated cobas 4800 System, complementing the cobas HPV (Human Papillomavirus)Test that received FDA approval in April. (news-medical.net)
This new test will give labs in the U.S. an efficient solution for offering clinicians chlamydia and gonorrhea screening using the preferred specimen types,' said Paul Brown, head of Roche Molecular Diagnostics. (news-medical.net)
However, following Pap screening, there should be a clinical indication for reflex additional testing of liquid cytology specimens for chlamydia and gonorrhea since these specimen types are more widely used in older populations at low risk for infection. (cdc.gov)
STD's: Tests for both chlamydia and gonorrhea are accurate if done by CDC standards, but if one develops a discharge or odor , retesting is advised. (ammoliteprodukties.nl)
The co-infection rate with organisms like chlamydia and Mycoplasma genitalium is high in some populations (up to 50% for chlamydia), and the incubation period for chlamydia can be significantly longer than that of gonorrhea. (smartsexresource.com)
Given the emerging resistance we have seen globally in gonorrhea strains, some experts believe there to be a theoretical 'antimicrobial resistance benefit' in treating gonorrhea with two agents with different molecular targets. (smartsexresource.com)
BACKGROUND: Regular chlamydia and gonorrhea testing are essential for key populations, such as female sex workers (FSWs). (bvsalud.org)
However, testing cost, stigma, and lack of access prevent FSWs in low- and middle-income countries from receiving chlamydia and gonorrhea testing. (bvsalud.org)
OBJECTIVE: This cluster randomized controlled trial examined the effectiveness and cost of the pay-it-forward strategy in increasing access to chlamydia and gonorrhea testing among FSWs in China. (bvsalud.org)
The 4 clusters were randomized into 2 study arms in a 1:1 ratio: a pay-it-forward arm (offered chlamydia and gonorrhea testing as a gift) and a standard-of-care arm (out-of-pocket cost for testing: US $11). (bvsalud.org)
The primary outcome was chlamydia and gonorrhea test uptake, as ascertained by administrative records. (bvsalud.org)

Mycoplasma hominis may also be found in this population, but at lower frequencies, quite often in association with ureaplasmas. (medscape.com)
Mycoplasma hominis and Ureaplasma species, known collectively as the genital mycoplasmal organisms, are generally considered opportunists that cause invasive infections in susceptible populations. (medscape.com)

Chlamydia co-testing and testing for other STIs is recommended due to high rates of co-infection. (wikipedia.org)
Related to erythromycin, azithromycin is considered by many to be the treatment of choice for Chlamydia trachomatis genitourinary infection because it may be administered in a single dose, which improves adherence to treatment. (medscape.com)
Differences in somatometric measurements and clinical variables in newborns with respiratory distress and infection between different Chlamydia trachomatis genotypes. (analesdepediatria.org)
We tested 1062 bronchial lavage samples from neonates with respiratory distress syndrome for Chlamydia infection. (analesdepediatria.org)
Screening programs have been demonstrated to reduce both the prevalence of C. trachomatis infection and rates of PID in women (79,80). (cdc.gov)
Despite preventive programmes and substantial knowledge about AIDS the incidence of HIV infection remains high in this rural population. (bvsalud.org)
Chronic infections, particularly those which are primarily characterized by an asymptomatic intracellular life cycle, e.g., latent Mycobacterium tuberculosis infection (LTBI), hepatitis B virus (HBV) infection, Chlamydia trachomatis infection, cytomegalovirus (CMV) or Epstein-Barr virus (EBV) infections, present a unique premise to decipher the fine balance between protective host immune responses, immunopathology and full-fledged clinical disease. (frontiersin.org)
2021) Impact of Severe Acute Respiratory Syndrome Coronavirus 2 Infection on Pregnancy Outcomes: A Population-based Study. (vircell.com)
Since Chlamydia trachomatis is one of the most common causes of PID and it is known to initiate HSP-60 induced CD8+ T-cell mediated cytotoxicity by molecular mimicry in Reiter's disease, we decided to look for evidence of C. trachomatis infection in patients of SLE. (healthcaremagic.com)
Reiter's disease is the one established to be triggered by Chlamydia Trachomatis nongonococcal infection. (healthcaremagic.com)
The prevalence of endocervical CT infection in women with SLE is low and similar to that of the normal population. (healthcaremagic.com)
The research in the Division of Microbiology & Parasitology comprises a wide range of topics including: bacterial motility and flagellar biogenesis, mechanisms of entry of bacteria into mammalian cells, bacterial toxin export and multi-drug efflux, regulation of gene expression during host-pathogen interaction, transmission, cell-cycle dynamics and virulence mechanisms in malaria parasites, host modulation by parasitic organisms and dynamics of parasitic worm infection in human populations. (cam.ac.uk)

The registrational trial for the cobas CT/NG test also confirmed that self-collected vaginal specimens and male urine specimens provide increased sensitivity and specificity when compared with alternative specimen types across patient populations with both low and high disease prevalence. (news-medical.net)
Although chlamydia prevalence data have provided a basis for setting age guidelines for routine annual screening and behavioral guidelines for targeted screening in women (11), no such consensus has been reached regarding control program definitions in men who have sex with women (12). (cdc.gov)
Although there are no recommendations to screen heterosexual men, it USPSTF suggests testing to test sexually active heterosexual men in clinical settings with a high prevalence of C. trachomatis (e.g. (cdc.gov)
The growth of this market is driven by technological advancements in molecular diagnostics, the increasing use of PoC diagnostic tests, an increase in funding for the R&D of diagnostic products, the rising geriatric population, and the increasing prevalence of target diseases. (meticulousresearch.com)

Chlamydia trachomatis is a ubiquitous human pathogen that is responsible for the most prevalent bacterial sexually transmitted diseases (STDs) worldwide ( 1 ). (cdc.gov)
The population structure and evolutionary forces within the pathogen population were analyzed. (peerj.com)
Early work by O'Rourke & Stevens (1993) using electrophoretic analysis of enzymes of the pathogen and serological methods suggested that gonococci have a non-clonal sexual or panmictic population structure. (peerj.com)
Here, we used the Acanthamoeba symbiont Protochlamydia amoebophila, a distant relative of the human pathogen Chlamydia trachomatis and representative of a large group of protist-associated environmental chlamydiae, as a model to study how obligate intracellular symbionts evolve and adapt to elevated temperature, a prerequisite for the pivotal evolutionary leap from protist to endothermic animal hosts. (univie.ac.at)
Centralisation, tendering, and "packaged" contracts means that we are increasingly relying on just the one molecular assay to diagnose a particular pathogen within a large geographical area. (microbiologymatters.com)
Laboratories or regions, or even countries which just rely on just one molecular test to diagnose a pathogen are always vulnerable to "escape mutants" such as nvCT emerging which escape detection and thus thrive in the population. (microbiologymatters.com)

Chlamydia trachomatis is the leading cause of preventable blindness and bacterial sexually transmitted diseases worldwide. (cdc.gov)
CtGEM typing was developed to subdivide the bacterial species Chlamydia trachomatis on the basis of genome phylogeny and anatomical tropism. (edu.au)
While Doxy-PEP is an effective strategy to prevent bacterial STIs such as chlamydia, gonorrhoea and syphilis among GBMSM, the risk/benefit calculation is most favourable for the prevention of syphilis. (ashm.org.au)
We established 12 replicate populations under two temperatures (20 °C, 30 °C) for 510 bacterial generations (38 months). (univie.ac.at)
To further improve the sensitivity of the Chlamydia Rapid test for testing male urine, a unique and innovative device, FirstBurstf0e4, was developed by DDU for convenient collection of the initial fraction of the urine stream containing 84% of the bacterial load (Wisniewski et al, JCM 2008). (ref.ac.uk)

According to global consensus, CT and NG are among the most common STIs, while UU is presented with approximately 70% of sexually active women and men in the global population. (pluslife.com)
These may include harms to individuals taking Doxy-PEP, such as disruptions to their microbiome and increased antimicrobial resistance (AMR) in STIs and other organisms, and harms to the community through increased population-level AMR. (ashm.org.au)
Trials of a new, molecular Point-of-Care test for sexually transmissible infections (STIs) found it substantially increased the timeliness of treatment. (eventscloud.com)
How Chlamydia trachomatis evades immune recognition and establishes long-term infections, m odulation of genital immunity by the vaginal microbiota, and e valuation of novel preventative strategies for STIs and HIV. (lsuhsc.edu)

Although a few studies have described methods for segregating clones of laboratory-adapted C. trachomatis clinical and reference strains ( 12 , 15 , 16 ), none has clonally purified all 19 C. trachomatis reference strains nor determined optimal methods to clonally segregate clinically mixed samples. (cdc.gov)
Methods Participants (n=5158, aged 15-59 years) were included from three independent nationwide population-based serosurveillance studies in 1996, 2007 and 2017. (bmj.com)
Despite increasing application of molecular diagnostic methods for the detection of sexually transmitted infections, the cytological findings in pap smears of patients with pathogens that can be identified only by PCR are not yet well described. (hindawi.com)
METHODS: TDR to retrotranscriptase and protease inhibitors included in the WHO TDR list 2009 implemented in the Calibrated Population Resistance tool v8.0 (Stanford) were studied in HIV pol sequences from all HIV-diagnosed adolescents (12-19-year-old) enrolled during 2004-2019 period in the Spanish pediatric and adult (CoRISpe-CoRIS) cohorts. (bvsalud.org)
In A. C. Brown (Ed.), Chlamydia trachomatis: Methods and Protocols (1 ed., pp. 87-122). (edu.au)
Chlamydia trachomatis: Methods and Protocols. (edu.au)
pp. 87-122 (Methods in Molecular Biology). (edu.au)
Recent studies applying sensitive molecular methods, such as PCR, have highlighted the role of viruses in acute wheezing and asthma attacks in children. (medscape.com)

183194 − Chlamydia / Gonococcus, Nucleic Acid Amplification. (ammoliteprodukties.nl)

The diagnosis of Chlamydia was made by plasmid detection with an in-house PCR assay, and genotypes were identified using a PCR-RFLP assay for the ompA gene. (analesdepediatria.org)
Recurrent use of assays & kits in the detection of various diseases through molecular diagnostics, rise in product approvals, and technological advancements in molecular techniques contribute to the large market share of this segment. (meticulousresearch.com)
Since these organisms require highly specialized conditions for culture in vitro and because molecular-based detection is not widely available (except for M genitalium), clinicians must be aware of the clinical syndromes with which these organisms have been associated and have a high level of suspicion prompting them to order the appropriate diagnostic tests from reference laboratories. (medscape.com)
LBC performed by cytocentrifugations are inexpensive, reduce inadequate smears, show excellent efficiency and allow HPV detection by molecular biology. (cytojournal.com)
The main advantages of this technique are to reduce the number of inadequate smears and to provide enough cells for the detection of infectious agents such as human papillomavirus (HPV) through molecular biology techniques [ 1 - 3 ]. (cytojournal.com)
The sensitivity improvement of SAS for the detection of the Chlamydial lipopolysaccharide was used to develop a simple Chlamydia rapid test with sufficient sensitivity that enabled the use, for the first time of non-invasive samples such as self-collected vaginal swab from women and urine from men. (ref.ac.uk)

Separation of these species is not possible except via molecular techniques such as polymerase chain reaction (PCR). (medscape.com)

Yet, the chlamydiae are a much larger group of evolutionary ancient obligate intracellular bacteria that includes predominantly symbionts of protists and diverse animals. (univie.ac.at)
Studying the intracellular biology of the obligate intracellular bacterium Chlamydia trachomatis . (cam.ac.uk)

Our results provide insights into the molecular evolution of intracellular bacteria under the constraints of strict host dependance and highly structured populations and suggest that for chlamydial symbionts of protists, temperature adaptation was facilitated through attenuation of symbiont infectivity as a tradeoff to reduce host cell burden. (univie.ac.at)

Among gay, bisexual, and other men who have sex with men (GBMSM), clinical trials of Doxy-PEP have shown significant reductions in syphilis (by 70-80%) and chlamydia (by 70-90%), and to a lesser degree, gonorrhoea (ineffective in some trials, or 50-55% reduction in other trials, due to varying levels of tetracycline resistance in gonococcal isolates in different populations). (ashm.org.au)

SARS-CoV-2 in Asturias, an autonomous community of Spain with a large ageing population, and high levels of migration and tourism, was monitored and tracked from the beginning of the pandemic in February 2020 until its decline and stabilization in August 2021, and samples were characterized using whole genomic sequencing and single nucleotide polymorphisms. (bvsalud.org)
Only 138 non-synonymous mutations occurring in more than 1â % of the population with SARS-CoV-2 were found, identifying ten major variants worldwide (seven arose before January 2021), 19 regional and one local. (bvsalud.org)

Plaque assays have been used to clonally segregate laboratory-adapted C. trachomatis strains from mixed infections, but no assays have been reported to segregate clones from recent clinical samples. (cdc.gov)
We then used infectivity assays and pooled whole-genome resequencing to identify any evolved phenotypes and the molecular basis of adaptation in these bacteria. (univie.ac.at)

Chlamydia pneumoniae and, in recent studies, Chlamydia trachomatis , may not only induce asthma exacerbations but may also be involved in the pathogenesis of chronic asthma. (medscape.com)

Strains with resistance phenotypes to more recent antibiotics ( azithromycin and cefixime ) were mostly found in two of the five population subgroups. (peerj.com)
High levels of recombination could confound studies of the gonococcal populations, especially if the studies are based on few genetic loci within strains as compared to the entire genomes. (peerj.com)
The rationale was facilitation of surveillance for ocular strains, although the method is applicable to essentially any C. trachomatis surveillance application that does not require high resolution. (edu.au)

Chlamydiae like Chlamydia trachomatis and Chlamydia psittaci are well-known human and animal pathogens. (univie.ac.at)

Failure to identify an inflammatory agent in pap smear with intense neutrophil exudate may suggest the presence of Ureaplasma parvum , Ureaplasma urealyticum , Chlamydia trachomatis , or Trichomonas vaginalis . (hindawi.com)

Association between Chlamydia trachomatis genotypes and clinical features of the newborn. (analesdepediatria.org)

We observed an overall reduction in infectivity of the symbionts evolved at 30 °C, and we identified numerous nonsynonymous mutations and small indels in these symbiont populations, with several variants persisting throughout multiple time points and reaching high frequencies. (univie.ac.at)

One, rg1, is within a hypothetical gene annotated as Jali-1891 within the C. trachomatis B_Jali20 genome. (edu.au)
The "Ca. Clavichlamydia salmonicola" genome harbors genes that so far have been exclusively found in Chlamydia species suggesting that basic mechanisms important for the interaction with chordate hosts have evolved stepwise in the history of chlamydiae. (univie.ac.at)

Respecto a la situación de las ITS en Medellín, destacamos dos estudios recientemente publicados, en donde en un grupo seleccionado de pacientes habitantes de la calle, se encontró que la prevalencia de N. gonorrhoeae era de 22,6 %, seguido de C. trachomatis (A-K) con 19,2 % [11] . (researchgate.net)
Asimismo, en el otro estudio realizado en 'personas con experiencia de vida en la calle', se encontró que la prevalencia de N. gonorrhoeae y C. trachomatis (A-K) era de 18 % y 14,6 %, respectivamente [12]. (researchgate.net)
AMR evolution should be considered in the context of the genetic structure of the N. gonorrhoeae population. (peerj.com)
C. trachomatis and N. gonorrhoeae control efforts in men differ substantially from those recommended for women. (cdc.gov)

Proceedings of the IAOS Satellite Meeting on Measuring Small and Indigenous Populations. (otago.ac.nz)

In 2006, a drop in Chlamydia trachomatis diagnoses was noticed on a particular molecular platform X, but not on others in use within Sweden. (microbiologymatters.com)

Clinics and sexual health services in the US and Europe generally require more than a few days of turnover time from samples to results, not to mention resource-limited areas where costs of molecular tests remain the biggest barrier as well as laboratory tests are not accessible at a population level. (pluslife.com)
The laboratory testing approach for molecular diagnostics has many advantages over other approaches. (meticulousresearch.com)

Doxycycline, a well-absorbed tetracycline derivative, is the second drug of choice for genital chlamydia infections. (medscape.com)

While tetracyclines, macrolides, lincosamides, and quinolones have historically been used for treatment of infections due to these organisms, acquired resistance is now well documented and varies according to drug, organism, and patient population. (medscape.com)

Eight (30.77%) cases and 3 (6.38%) controls tested positive for C. trachomatis antibodies . (healthcaremagic.com)
Protective mechanisms of monoclonal antibodies and vaccine induced immunity in high-risk immunocompromised populations. (lsuhsc.edu)

Background: Sexually transmitted diseases (STDs) management in sub-Saharan Africa is syndromic but molecular diagnostics provide quicker, sensitive diagnosis and treatment. (bvsalud.org)

The story of the Swedish variant also demonstrates the importance of using the percentage positivity rate of a molecular test over time as a Quality Control measure. (microbiologymatters.com)

2018) Valoración de un nuevo ensayo quimioluminiscente en comparación con ELISA en la detección de IgG contra el virus de la hepatitis E. Revista de la Sociedad Andaluza de Microbiología y Parasitología Clínica. (vircell.com)
Three tests (Chlamydia, Hepatitis B and HIV) were launched since 2008, with test kits marketed, allowing patients to receive treatment for infections which would have previously gone unnoticed and untreated. (ref.ac.uk)

Journal of Experimental Zoology Part B: Molecular and Developmental Evolution , 334 (3), 149-155. (pressbooks.pub)

In contrast, the majority of chlamydia and gonorrhoea infections among GBMSM are asymptomatic, and they rarely cause complications. (ashm.org.au)

Uncovering molecular mechanisms underpinning flagellum assembly. (cam.ac.uk)

Census weights were assigned to achieve seroprevalence estimates representative of the general Dutch population. (bmj.com)

However, rapid population growth, unplanned urbanization, increased international travel, and the presence of virus major vector (Aedes aegypti) in the country suggest that DENV transmission may occur. (unl.pt)

According to this latest publication from Meticulous Research ® , the Europe molecular diagnostics market is projected to reach $13.25 billion by 2030, at a CAGR of 4% from 2023 to 2030. (meticulousresearch.com)

Molecular epidemiology and evolutionary trajectory of emerging echovirus 30, Europe. (szu.cz)

In vitro susceptibility testing and molecular resistance testing may be useful to guide therapy, especially for disseminated infections if available. (medscape.com)

Labcorp test details for Chlamydia/Gonococcus, NAA. (ammoliteprodukties.nl)
Chlamydia Test: Types, Purpose, Procedure & Results Skip to main contented. (ammoliteprodukties.nl)
This concept is particularly applicable to microbes which are diagnosed by molecular techniques such as PCR where only a minor mutation or deletion can potentially create sufficient change in the base sequence to make the microbe undetectable by the original molecular test. (microbiologymatters.com)

The objective was to describe the transmitted drug resistance mutations (TDR) and its transmission by clusters in this population in Spain. (bvsalud.org)

Molecular and phylogenetic analyses of Salmonella Gallinarum trace the origin and diversification of recent outbreaks of fowl typhoid in poultry farms. (cdc.gov)

Objectives To report sex and age-specific Chlamydia trachomatis (Ct) seroprevalence estimates in the general population of the Netherlands between 1996 and 2017 and identify risk factors associated with Ct seropositivity. (bmj.com)

However, unfavorable regulatory framework and cost of molecular diagnostic tests hamper the growth of this market to a notable extent. (meticulousresearch.com)

Among the products & services included in the report, in 2023, the kits & reagents segment is expected to account for the largest share of the Europe molecular diagnostics market. (meticulousresearch.com)

Possibility of chlamydia triggering SLE cannot be ruled out. (healthcaremagic.com)

Conclusions We have not found evidence for a decrease in population seroprevalence in those under 25 years old despite decades of intensified testing-and-treatment efforts in the Netherlands. (bmj.com)
However, diversity decreased in conspecific host populations found at lower altitudes in Sudanian bioclimatic zone. (microbial-ecology.net)

She began her career on tropical diseases as a malaria molecular parasitologist at the London School of Hygiene and Tropical Medicine (LSHTM), with a EMBL fellowship. (edu.au)
trachomatis infections are the leading cause of sexually transmitted diseases in the United States. (ammoliteprodukties.nl)

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