We studied the stability of colloidal suspensions of iron oxide nanoparticles with grafted poly(ethylene glycol) of various molecular weights in aqueous media, buffers, and cell culture media. (aiche.org)
b) It contains no more than 0.2 percent total by weight of ethylene and diethylene glycols if its mean molecular weight is 350 or higher and no more than 0.5 percent total by weight of ethylene and diethylene glycols if its mean molecular weight is below 350, when tested by the analytical methods prescribed in § 172.820(b) of this chapter. (fda.gov)
In this study, poly(ethylene glycol) (PEG) was used as a plasticizer for BPS. (materialstoday.com)
Polyethylene glycol is a family of long chain polymers made up of ethylene glycol subunits. (sci-toys.com)
To solve these problems, an amphiphilic polymer-drug conjugate was prepared by attachment of low molecular weight (ie, 2 kDa) methoxy poly(ethylene glycol) methyl ether (mPEG) to gambogic acid (GA-mPEG 2000 ) through an ester linkage and characterized by 1H nuclear magnetic resonance. (dovepress.com)
A series of monomethoxy poly(ethylene glycol)-poly(lactide) (mPEG-PLA) diblock copolymers were synthesized, and mPEG-PLA micelle was fabricated and used as a nanocarrier for solubilization and delivery of a promising anticancer drug ethaselen. (springer.com)
Here, we describe poly (ethylene glycol) dimethacrylate (PEGDMA)-based microparticles, in the shape of microrods, loaded with beta nerve growth factor (β-NGF) for the purpose of promoting fracture repair. (frontiersin.org)
For this purpose, we used tetra-poly(ethylene glycol) (tetra-PEG) gel, whose network parameters are well known, as the polymer backbone, and we succeeded in tuning the swelling of the gel by a factor of 1500 times while maintaining the topological structure of the network unchanged, using an approach combining a molecular stent method and a PEG dehydration method. (rsc.org)
Experiments: In this work, we specifically synthesize poly (ethylene glycol) (PEG) chains, grafted onto poly(styrene) (PS) particles in aqueous solution, and adjust the conditions so that strongly anisotropic and isolated polymer-like clusters are formed. (lu.se)
Polymers4
Multiple Linear Regression Modeling To Predict the Stability of Polymer-Drug Solid Dispersions: Comparison of the Effects of Polymers and Manufacturing Methods on Solid Dispersion Stability MOLECULAR PHARMACEUTICS. (nottingham.ac.uk)
Polyethylene glycols or PEGs are water-soluble polymers that are used in many pharmaceutical formulations. (imcdgroup.com)
Biodegradable polymers, especially aliphatic polyesters such as polylactide (PLA), poly(DL-lactic-co-glycolic acid) (PLGA) and poly( ε -caprolactone) (PCL) have attracted much attention as biomaterials due to their biocompatibility, degradability and nontoxicity. (springer.com)
Whereas theoretical predictions of macromolec- use of nonadsorbing polymers, like polyethylene glycol, for ular crowding effects abound, there are remarkably few protein separation (Albertsson, 1986) and crystallization experimental studies of this universal phenomenon. (lu.se)
In OSDs, higher molecular weight PEGs can impart plasticity to granules, enhance the effectiveness of binder and can be used as lubricants for tablets. (imcdgroup.com)
Higher molecular weight PEGs as PEG 1000, PEG 1450 and PEG 3350 can form networks or microstructures. (imcdgroup.com)
Discover our selection of polyethylene glycol (PEGs) and PEG derivatives in a wide range of molecular weights for all your PEGylation needs and applications. (sigmaaldrich.com)
PEGs with small molecular weight such as PEG-300, PEG-400, and PEG-600 are rich in moisturizing properties and can be used as moisturizers for toothpaste, facial cleansing foam, hair care products, and wet wipes. (sanyo-chemical-solutions.com)
PEG-4000S, PEG-6000S, and other PEGs with large molecular weights have a high binder effect and are water soluble, so they can be used as binders for solid face powders and enzymes for detergents. (sanyo-chemical-solutions.com)
Little is known regarding the accumulation of high-molecular-weight PEGs or the long-term effects resulting from PEG accumulation in certain tissues, especially the choroid plexus. (bvsalud.org)
Average molecular weight2
The name may be followed by a number which represents the average molecular weight (e.g. macrogol 3350, macrogol 4000 or macrogol 6000). (wikipedia.org)
The average molecular weight of urinary hyaluronan (5,500 Da) was constant through all generations. (go.jp)
Biology4
Molecular imaging is an emerging field that integrates advanced imaging technology with cellular and molecular biology. (hindawi.com)
Molecular imaging is a rapidly developed multidiscipline which involves molecular biology, chemistry, computer, engineering, and medicine [ 1 ]. (hindawi.com)
Over the past decade, with the progress of molecular biology and radiochemistry, a variety of tracer with high specificity and affinity appeared. (hindawi.com)
We find applications both in the biophysical/molecular biology field and in the industrial area. (lu.se)
BPS and PEG are miscible, and the effect of PEG molecular weight (in the range of 200-600 g/mol) and concentration on the T g of BPS/PEG blends was investigated. (materialstoday.com)
Despite the low molecular weight of the PEG side chain, polysiloxane and PEG assemble into microdomains with covalently bound phosphonium cations at the interface. (aps.org)
For example, PEG with high molecular weight is used as a water-soluble binder, PEG with low molecular weight is used as a plasticizer, and PEG is also used as a dispersant, lubricant, heat medium, sensitizer, dust-proofing agent, etc., to express functions suitable for a variety of applications. (sanyo-chemical-solutions.com)
MDI is a low molecular weight allergen and occupational exposure is associated with allergic sensitization, dermatitis, and asthma. (cdc.gov)
15002
Polyethylene glycol (PEG) is safe and water-soluble, so PEG₋1500 can be used as a water-soluble base for cosmetic creams and hand creams, and PEG-400 as a water-soluble base for lotion. (sanyo-chemical-solutions.com)
Following 6 biweekly immunizations, splenocytes were recovered 72 h after the final immunization and fused to Sp2/0-Ag14 myeloma cell line using 50% polyethylene glycol (1500 MW) for hybridoma production. (cdc.gov)
Toxicity1
Polyethylene glycol (PEG) is a highly safe compound with low irritation and toxicity. (sanyo-chemical-solutions.com)
It can realize noninvasive and real time visualization, measurement of physiological or pathological process in the living organism at the cellular and molecular level, providing an effective method of information acquiring for diagnosis, therapy, and drug development and evaluating treatment of efficacy. (hindawi.com)
It can realize noninvasive and real time visualization, measurement of physiological or pathological process in the living organism at the cellular or molecular level [ 2 , 3 ]. (hindawi.com)
American Journal of Physiology: Lung Cellular and Molecular Physiology. (lu.se)
Weights2
In this study, seven PolyILs were synthesized having degrees of polymerization ranging from 1 to 333, corresponding to molecular weights (MW) from 482 to 160 400 g/mol. (osti.gov)
It is the prototype of the primary immunodeficiency diseases and is caused by numerous molecular defects that lead to severe compromise in the number and function of T cells, B cells, and occasionally natural killer (NK) cells. (medscape.com)
Polymer1
One route to melt processing of high glass transition temperature polyelectrolytes, such as disulfonated poly(arylene ether sulfone) (BPS), involves mixing a plasticizer with the polymer. (materialstoday.com)
Approaches2
This approach represents a pathway to form nanostructures that circumvent amphiphilicity and packing parameter constraints and generates structures that are not achievable by self-assembly alone, nor top-down approaches, broadening the utility of molecular nanomaterials for new targets. (nature.com)
We report on results of experimental, morphological, and molecular approaches and discuss the potential risk for future human cases, given the existence of food habits in the country involving the ingestion of raw fish. (cdc.gov)
Reactions1
Although polyethylene glycol is considered biologically inert, it can form non-covalent complexes with monovalent cations such as Na+, K+, Rb+, and Cs+, affecting equilibrium constants of biochemical reactions. (wikipedia.org)
20181
I was also co-founder and Technical Development Director of a successful spin-out, Molecular Profiles Ltd (which became Juniper Pharma in 2013 and was acquired by Catalent in 2018). (nottingham.ac.uk)
Adhesives1
c) The provisions of paragraph (b) of this section are not applicable to polyethylene glycols used in food-packaging adhesives complying with § 175.105 of this chapter. (fda.gov)
Elucidate2
In this work, we intended to investigate the relationship between the swelling ratio Q and Young's modulus E of hydrogels from their contracted state to extreme swelling state and elucidate the underlining molecular mechanism. (rsc.org)
Molecular markers have been used to elucidate the genetic variability among S. mutans isolated from saliva and other sources. (bvsalud.org)
Tumor1
A lot of preclinical and clinical studies have confirmed the feasibility of using radionuclide molecular imaging to detect tumor and predict response to therapy [ 12 , 13 ]. (hindawi.com)
Chains1
A series of random polysiloxane-based copolymer single ion conductors with phosphonium and polyethylene glycol side chains have been synthesized at various compositions and counterions. (aps.org)
Methods1
PCR is still the go-to method in the molecular diagnostics industry but, with the rise of close-to-patient testing, isothermal amplification methods with their low power and potentially easier detection schemes look increasingly attractive. (ttp.com)
Represents1
In these-and nearly all conventional cases-molecular self-assembly represents the last step in the formation of nanostructures, likely because the structures tend to be intrinsically dynamic, causing them to rearrange, precipitate, or dissolve upon reaction. (nature.com)
Genetic1
Over the past few decades, the diverse molecular genetic causes of SCID have been identified with progress from studies of the immune system. (medscape.com)
High2
Molecular imaging requires high resolution and high sensitive instruments and specific imaging agents that link the imaging signal with molecular event. (hindawi.com)
Due to its advantages of high sensitivity and quantifiability, radionuclide molecular imaging plays an important role in clinical and preclinical researches [ 11 ]. (hindawi.com)
Group2
For small molecules to self-assemble in water, the overall molecular geometry must satisfy critical packing parameter constraints and, importantly, the head group of the constituent molecules must be sufficiently large and hydrophilic to counteract the hydrophobicity of the rest of the molecule 15 . (nature.com)
Because more than one polyethylene glycol group is introduced into the molecular, the scale and corrosion inhibition for calcium scale is improved. (phrmg.org)
Polyethylene glycol (PEG) is present in a variety of products. (bvsalud.org)
Formation1
This mechanism has been used to investigate the spontaneous formation of a PPR that occurs when grinding alpha-Cyclodextrin (alpha-CD) with polyethylene glycol (PEG). (unav.edu)
Water1
Polyethylene glycol (PEG) hydrogels are tunable cell culture platforms that recapitulate tissue geometry, water content, and bulk modulus. (umass.edu)
Drug2
Therefore, molecular imaging plays an important role in earlier detection, accurate diagnosis, and drug development and discovery [ 5 - 7 ]. (hindawi.com)
Recently, you have become aware of a new drug-polyethylene glycol (PEG). (bestbets.org)
Function1
These molecular defects interfere with lymphocyte development and function, blocking the differentiation and proliferation of T cells and, in some types, of B cells and NK cells. (medscape.com)
Cite1
In this review, we will discuss the characteristics of molecular imaging, the novel imaging agent including targeted imaging agent and multifunctional imaging agent, as well as cite some examples of their application in molecular imaging and therapy. (hindawi.com)
Method1
A highly sensitive method for measurement of urinary hyaluronan with a minimum molecular mass of 2,000 Da was developed without using HPLC or radioisotopes. (go.jp)