BiologyInteractionsProcessesEpigeneticGeneticsGenesSciencesPathways involvedElucidateGenetic and MolecularLund UniversityEtiologyPhenotypesMoleculeBacterialGenomicMutationsPathogenesisIntegratingMacromoleculesToxicityInvestigate the molecularMethodsApproachesDockingCompoundsResearchInteractionExposuresBiochemicalMammalianAggregationMoleculesTargets2023LaboratoryClinicalRecognitionImmuneResistanceProteinsMetabolismGene expressionCancerUnderstanding
Biology19
- Since its discovery, nearly one decade of research on astrocyte elevated gene 1 (AEG-1) has witnessed expanding knowledge of this molecule, ranging from its role in cancer biology to molecular mechanisms underlying the biological functions. (biomedcentral.com)
- Institute of Molecular Biology and Tumor Research (IMT) Hans-Meerwein-Str. (uni-marburg.de)
- Computational Biology is the newest route within the Biological Sciences degree programme and was designed to offer a dedicated framework for those students who wish to take a computational approach to the study of biology. (ucl.ac.uk)
- Computational biology involves the application of computers and computer science to the understanding and modelling of biological structures and processes. (ucl.ac.uk)
- The range of topics covered will equip the students with the knowledge and skills to address biological problems in genetics, cell biology, evolutionary biology and ecology using a variety of computational tools and analytical approaches. (ucl.ac.uk)
- Our Biological Sciences (Zoology) degree is aimed at anyone interested in the broad field of animal biology. (cardiff.ac.uk)
- Students planning to major in the Biological Sciences should have three years of Mathematics and one year each of Biology, Physics, and Chemistry in high school. (wiu.edu)
- Research in the Department of Biology spans the entire breadth of biology: from ecology and evolution to molecular, cellular, and developmental biology. (tamu.edu)
- Many departmental faculty members actively participate in campus-wide interdepartmental graduate and research programs, including Genetics, Neuroscience, Molecular and Environmental Plant Sciences, and Ecology, Evolution, and Behavioral Biology. (tamu.edu)
- The Mechanisms of Biological Resilience (MBR) research group in the Department of Biology studies the compensatory mechanisms which living organisms and ecosystems employ to mitigate external stress and alleviate their adverse effects. (tamu.edu)
- Systems Biology Modelling: Molecular mechanisms using genome-scale metabolite networks and other biological networks. (uni-potsdam.de)
- In the area of the philosophy of biology, he has researched the process of cryptobiosis and biological innovations. (ucm.es)
- Critical Reviews in Biochemistry and Molecular Biology. (cdc.gov)
- The Center for Molecular Protein Science (CMPS) brings together scientists active within the fields of biochemistry, molecular biophysics, structural biology, and physical and theoretical chemistry. (lu.se)
- Our research focuses on major areas of modern biochemistry and molecular biology. (lu.se)
- I was fascinated with topics such as the central dogma of molecular biology and protein synthesis, which are about the mechanisms of gene expression. (who.int)
- After my master's degree, I was sure I wanted to pursue research as a career, and while selecting my PhD research topic I came across the field of epigenetics, which is the branch of molecular biology that deals with gene regulation. (who.int)
- Training/knowledge of immunology, as well as experience with cell culture and molecular biology are both desired but not required. (lu.se)
- This course is optional for a Master's degree in Science with a major in Biology or in Molecular Biology. (lu.se)
Interactions7
- A new study of molecular interactions central to the functioning of biological clocks explains how certain mutations can shorten clock timing, making some people extreme "morning larks" because their internal clocks operate on a 20-hour cycle instead of being synchronized with the 24-hour cycle of day and night. (medicalxpress.com)
- The structures reveal the specific molecular interactions between SRP and the emerging signal sequence and the elements that regulate GTPase activity of SRP·SR. Our results suggest the molecular mechanism of how eukaryote-specific elements regulate the early and late stages of SRP-dependent protein targeting. (nih.gov)
- Zebrafish Fin: Complex Molecular Interactions and Cellular Mechanisms Guiding Regeneration. (uni-ulm.de)
- We will emphasize biological nutrient and energy cycling, population dynamics, animal and plant species interactions, disturbances and response to disturbances, and ecology in urban and agricultural landscapes. (macalester.edu)
- We describe a computational methodology allowing to systematically and quantitatively characterize a Boolean mathematical model of a biological network in terms of genetic interactions between all loss of function and gain of function mutations with respect to all model phenotypes or outputs. (researchgate.net)
- However, the molecular interactions between ibuprofen and the cell membrane are not well understood. (iasp-pain.org)
- We want to understand the molecular mechanisms of biological processes by exploring the structure, dynamics, interactions and function of proteins. (lu.se)
Processes7
- 2. Understanding major biological processes at the cellular and molecular level, through the application of methods drawn from structure, function, and genetics. (ui.ac.id)
- The research will mainly focus on four biological processes including possible alterations of the epigenome, neuroendocrine system, inflammatome, and the gut microbiome. (plos.org)
- On the contrary there is extensive evidence that fluoride can interfere with many important biological processes. (fluoridealert.org)
- We describe an approach and potential applications for using the FICSME to elucidate the mechanisms of globally important ecological and physical processes, toward attaining the goal of predicting the structure and function of microbial communities in chemically complex natural environments. (frontiersin.org)
- Multi-Omics Data Analysis: Integration of genomic data with intermediate molecular data to comprehensively interpret biological processes. (uni-potsdam.de)
- Mechanisms of membrane-associated cell biological processes. (harvard.edu)
- Integrated multi-omics approach identified molecular mechanism and pathogenetic processes of COVID-19 that affect patient with Parkinson's disorder. (cdc.gov)
Epigenetic4
- From this research, several molecular and epigenetic mechanisms have been discovered. (wikipedia.org)
- In coordination with these factors, molecular and epigenetic mechanisms influence the progression toward alcoholism. (wikipedia.org)
- Research has and continues to investigate the molecular and epigenetic mechanisms underlying the downward spiral of alcoholism. (wikipedia.org)
- The first focuses on understanding the epigenetic mechanisms of oesophageal squamous cell carcinoma (ESCC) in high-incidence populations in low- and middle-income countries in Africa, South-East Asia, and South America. (who.int)
Genetics2
- Disentangling the underlying biological mechanisms poses the next great challenge for large-scale genetics. (dana-farber.org)
- Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases 2020 0 0. (cdc.gov)
Genes3
- METHODS: For 154 EOA-genes we investigated (1) the associated phenotype (2) reported anatomical neuroimaging abnormalities, and (3) functionally enriched biological pathways through in silico analysis. (lu.se)
- Our discovery of critical genes and molecular events presents interesting avenues for mechanistic studies and biomarker development for early diagnosis in low-resource settings. (who.int)
- While sex differences are attributed to the combined effects of sex hormones, sex chromosomes and societal factors, it is still unknown how biological sex influences genes and pathways in immune cells that significantly impact immune responses. (lu.se)
Sciences8
- A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). (mdpi.com)
- For information on entry requirements, fees, how to apply and much more visit the MSci Biological Sciences prospectus page . (ucl.ac.uk)
- Your degree title also remains flexible up until your final year, so that you can either continue with BSc Biological Sciences (Zoology) to graduation, or switch to another of our bioscience degrees during your first two years of study. (cardiff.ac.uk)
- In addition, students become qualified to pursue graduate studies in any of several areas of study within the Biological Sciences and the health professions. (wiu.edu)
- Cellular and Molecular Life Sciences, 78, 5123-5138. (uni-potsdam.de)
- Below are the most recent news items related to the Department of Biological Sciences. (calstatela.edu)
- Tyler Powell is a 2nd-year Biological Sciences M.S. student in Dr. Edith Porter's innate immunology lab. (calstatela.edu)
- Saudi journal of biological sciences 2021 0 0. (cdc.gov)
Pathways involved2
- PCs are a diverse group of plant micronutrients, some of which modulate physiologic and molecular pathways involved in energy metabolism. (medscape.com)
- 3,8-9 In fact, there is a great interest in the understanding of its structure and its mechanism of action, particularly of the molecular pathways involved in its recognition and cellular signaling, 10-15 as well as the forms of its inactivation 3,16 . (bvsalud.org)
Elucidate2
- Thus, the aim of this work is to carry out a review of the literature on the role of bacterial endotoxin in the etiology of periapical lesions, its mechanism of action, and to elucidate molecular mechanisms involved in endotoxin's recognition by the immune system and cell activation. (bvsalud.org)
- Therefore, the objective of this study is to carry out a review of the literature on the role of bacterial endotoxin in the etiology of periapical lesions, as well as to elucidate molecular mechanisms involved in its recognition by the immune system and in cell activation. (bvsalud.org)
Genetic and Molecular1
- My laboratory works on the genetic and molecular mechanisms that regulate aging and aging-related disease. (berkeley.edu)
Lund University1
- In the Systems Immunology Lab at Lund University ( https://theconsigliolab.wordpress.com/ ), we investigate how biological sex impacts human immunity using systems immunology approaches. (lu.se)
Etiology1
- The other project is to understand the molecular etiology of colorectal cancer in countries in Central and Southern Europe. (who.int)
Phenotypes3
- 1) Integrating molecular phenotypes to decipher disease mechanisms. (dana-farber.org)
- These data can inform how genetic variants influence specific cellular phenotypes and provide an avenue for us to decipher genetic mechanisms. (dana-farber.org)
- The pathological mechanisms underlying comorbid EOA phenotypes remain largely unknown. (lu.se)
Molecule1
- Click molecule labels to explore molecular sequence information. (nih.gov)
Bacterial2
- Dr. Xu directs an applied microbiology and biotechnology lab at Cal State LA, where students conduct research on novel antibiotics and elucidation of mechanisms of pathogenesis of bacterial pathogens. (calstatela.edu)
- This information is important because endotoxin is released during multiplication or bacterial death, causing a series of biological effects that lead to an inflammatory reaction and resorption of mineralized tissues. (bvsalud.org)
Genomic4
- The focus of CeMBioS research group is to study the cellular, molecular, and genomic mechanisms which occur in the cells as an individual, as well as the building block of an organism including to the structure and function of the process underlying a biological system. (ui.ac.id)
- 3. Supporting advanced research within the cellular, molecular, and genomic area in the field of biodiversity conservation and prospection. (ui.ac.id)
- Our goals are to develop high-quality research, to train graduate students in cellular and molecular research, and to strengthen undergraduate education in the area of cellular, molecular and genomic mechanism. (ui.ac.id)
- Integrating molecular markers into metabolic models improves genomic selection for Arabidopsis growth. (uni-potsdam.de)
Mutations5
- A new study explains how mutations in either CK1 or PERIOD can throw off the timing of biological clocks in animals from fruit flies to humans. (medicalxpress.com)
- The study, published February 11 in eLife , shows that the same molecular switch mechanism affected by these mutations is at work in animals ranging from fruit flies to people. (medicalxpress.com)
- Other collaborators at UC San Diego performed simulations of the molecular dynamics of the switch showing how the CK1 protein switches between two conformations, and how mutations cause it favor one conformation over another. (medicalxpress.com)
- Can molecular data help us efficiently identify the specific causal mutations? (dana-farber.org)
- In the first case study, we observed that the real biological networks were most sensitive to overexpression/state-flip and edge-addition/-reverse mutations among node-based and edgetic mutations, respectively. (researchgate.net)
Pathogenesis1
- In this article, we provide an in-depth analysis of the evidence on several potential mechanisms of Long COVID and discuss their relevance to its pathogenesis . (bvsalud.org)
Integrating1
- We aim to develop statistical techniques for integrating molecular data to make sense of GWAS findings. (dana-farber.org)
Macromolecules1
- The imaging method is capable of capturing sequential pictures of the molecular changes of biological macromolecules at work. (eurekalert.org)
Toxicity1
- However, cardiotoxicity is the adverse reaction of drug dose cumulative toxicity, but the mechanism is still unclear. (frontiersin.org)
Investigate the molecular1
- We apply biochemical, molecular, cellular, structural and genome-wide approaches in order to investigate the molecular functions of specific proteins in chromatin and transcriptional regulation. (uni-marburg.de)
Methods4
- Bartlett, A. I. & Radford, S. E. An expanding arsenal of experimental methods yields an explosion of insights into protein folding mechanisms. (nature.com)
- Therefore, it is necessary to explore the potential mechanism of action of HGWD in RA treatment based on network pharmacology and molecular docking methods. (hindawi.com)
- The topics studied in this area include structure and bonding theories, reaction mechanisms and characterisation methods (NMR and molecular spectroscopy). (lu.se)
- Molecular biological methods, cell culture and tissue culture are treated to a less extent. (lu.se)
Approaches1
- Uncovering mechanistic links between emotional states, biological timing, sleep, and development of chronic diseases using interdisciplinary approaches. (tamu.edu)
Docking2
- Afterward, molecular docking was used to analyze the binding force of the top 10 active compounds with target proteins of VCAM1, CTNNB1, and JUN. (hindawi.com)
- The molecular docking results revealed that the top 10 active compounds of HGWD had a strong binding to the target proteins of VCAM1, CTNNB1, and JUN. (hindawi.com)
Compounds2
- In this comprehensive review, the accumulating evidence supporting the neuroprotective properties of seaweed-derived compounds is evaluated and their putative mechanisms of action are eluci. (researchgate.net)
- The course has a molecular perspective and a further aim to enable students to develop their ability to describe the structure and reactivity of coordination compounds and their applications in organometallic chemistry and homogeneous catalysis, and the significance of metals in biological systems. (lu.se)
Research4
- 1. Conducting basic research in the biological system. (ui.ac.id)
- A vast amount of research exists on the possible molecular mechanisms through which vitamin D affects cancer cell proliferation, cancer progression, angiogenesis, and inflammation. (mdpi.com)
- The study will research in detail how ELS converts into biological signals embedded simultaneously or sequentially in the brain, the cardiovascular and metabolic systems. (plos.org)
- I moved into research because I wanted to explore deeper into biological science from my high school days. (who.int)
Interaction3
- Protein-protein interaction (PPI) network was constructed to explore the potential mechanisms of HGWD on RA using the plugin BisoGenet of Cytoscape 3.8.0 software. (hindawi.com)
- Our lab studies host - microbe interaction at the cellular and molecular level and develops antimicrobials against the Gram-negative pathogen Pseudomonas aeruginosa . (vt.edu)
- Experimentally characterized genetic interaction networks in model organisms provide important insights into relationships between different biological functions. (researchgate.net)
Exposures1
- Knowledge about cancer biological mechanisms, exposures, and genetic susceptibility may well provide opportunities to develop precision prevention and early-detection strategies. (cdc.gov)
Biochemical2
- While the initial discovery of AEG-1 left with an abundance of controversial understanding of its biological functions and biochemical characteristics, which remains elusive to date, a few features of AEG-1 have been recognized with certain consensus. (biomedcentral.com)
- Here we provide biochemical and cellular evidence that artemisinins are potent inhibitors of Plasmodium falciparum phosphatidylinositol-3-kinase (PfPI3K), revealing an unexpected mechanism of action. (nature.com)
Mammalian1
- This mechanism of transmission contrasts with that of the two subspecies of African trypanosomes that cause human disease, Trypanosoma brucei gambiense and Trypanosoma brucei rhodesiense , which are transmitted via the saliva of their vectors, and with the mechanism by which a nonpathogenic trypanosome found in the Americas, Trypanosoma rangeli , is transmitted to its mammalian hosts. (medscape.com)
Aggregation2
- To avoid these dangers, cells invest in a complex network of molecular chaperones, which use ingenious mechanisms to prevent aggregation and promote efficient folding. (nature.com)
- These LDL particles are modified by a number of mechanisms, including enzymatic degradation, aggregation and oxidation. (europa.eu)
Molecules1
- A deep knowledge of their mode of action and of their biological targets may aid the design of new molecules with improved biological activities and limited side effects. (mdpi.com)
Targets1
- This Special Issue of the International Journal of Molecular Science on "Metallodrugs: mechanisms of action, molecular targets and biological activity 2.0" is a continuation of the first volume in 2021 ( https://www.mdpi.com/journal/ijms/special_issues/Metallodrugs_Molecular ), and aims to collect original contributions, letters or review articles describing recent advances in this field. (mdpi.com)
20231
- The Department of Biological Chemistry presents the Fall 2023 Seminar Series. (umich.edu)
Laboratory1
- Our laboratory focuses mainly on molecular mechanisms involved in gene repression. (uni-marburg.de)
Clinical1
- To that effect, it is imperative that the mechanisms underlying the clinical manifestations of Long COVID be elucidated. (bvsalud.org)
Recognition1
- These findings provide a unique perspective into the mechanism by which recognition of a single-stranded DNA sequence switches the translocating RecBCD from a destructive nuclease to a constructive component of recombinational DNA repair. (bris.ac.uk)
Immune1
- in fact, biological sex has a prominent influence in regulating immune responses. (lu.se)
Resistance1
- The emergence of these novel resistance mechanisms highlights the urgency of a more global and comprehensive approach to antimicrobial stewardship and preventing transmission of antibiotic-resistant pathogens between persons and institutions. (cdc.gov)
Proteins1
- What we discovered is this neat molecular switch that controls the abundance of the PER proteins. (medicalxpress.com)
Metabolism1
- In this study, proteomics and metabonomics techniques were used to analyze the tissue and plasma of DOX-induced heart failure (HF) in rats and to clarify the molecular mechanism of the harmful effects of DOX on cardiac metabolism and function in rats from a new point of view. (frontiersin.org)
Gene expression1
- In parallel, molecular measurements such as gene expression and chromatin activity across individuals are being collected at an unprecedented rate. (dana-farber.org)
Cancer4
- Atlas of Cancer Signalling Network: An Encyclopedia of Knowledge on Cancer Molecular Mechanisms. (routledge.com)
- She participates in multidisciplinary projects to decipher cell mechanisms rewiring in cancer. (routledge.com)
- Dancizo has researched the molecular mechanisms of thyroid cancer and the biogeography and phylogeny of Andean tardigrades. (ucm.es)
- I joined IARC in 2015, and I am a molecular biologist, with a specialty in cancer epigenetics. (who.int)
Understanding1
- Understanding these molecular mechanisms may enable scientists to develop therapies for intervening in the clock to alleviate disruptions, whether they are caused by inherited conditions or by shift work or jet lag. (medicalxpress.com)