Molecular imaging. Medical search. Frequent questions

In 2001, the ICRH/Heart and Stroke Foundation workshop on the Vulnerable Atherosclerotic Plaque identified imaging modalities that focus on the vulnerable plaque, including methodologies that allow functional assessment of plaque tissue should be targeted. (nih.gov)
While ICG-99mTc-nanocolloid is a sentinel node specific tracer that can be detected using nuclear medicine modalities and (near-infrared) fluorescence imaging, the hybrid concept can easily be expanded to (tumor) receptor-targeted tracers. (lumc.nl)
Other molecular imaging modalities, such as optical imaging and molecular ultrasound, use a variety of different agents. (snmmi.org)
Clinical molecular imaging is trending towards hybrid modalities such as PET-CT, SPECT, or PET-MR that provide high-resolution anatomical imaging. (pharmiweb.com)
The number of clinicians with both ABR and ABNM certifications has been on the rise over the past decade, he said, fueled by the use of hybrid imaging modalities and the desire to improve employment prospects. (auntminnie.com)

Image Credit: Ceccarelli and Du, 2022. (universetoday.com)

While the underlying biology represents a new arena for many imaging specialists, efforts such as development of novel agents, signal amplification strategies, and imaging technologies clearly dovetail with prior research efforts in the area of imaging. (nih.gov)
The 1999 NIH Bioengineering Consortium (BECON) "Biomedical Imaging Symposium: Visualizing the Future of Biology and Medicine" identified imaging at the cellular and molecular level as a critical need for goals such as the early detection of disease. (nih.gov)
The multidisciplinary field of molecular imaging of living subjects continues to expand with dramatic advances in chemistry, molecular biology, therapeutics, engineering, medical physics and biomedical applications. (stanford.edu)
The article in the JNM from Dr. Tsujikawa and colleagues provides an example of the unique capacity of molecular imaging to measure in vivo cancer biology," says David A. Mankoff, M.D., Ph.D., professor of radiology, medicine and bioengineering at the University of Washington and Seattle Cancer Care Alliance in Seattle. (brightsurf.com)
Challenges related to the best targeting approach, to translation of animal model results to the clinical setting, to adequate imaging methodology for visualization of coronary artery biology, and to a suitable target patient population will need to be overcome. (elsevier.com)
The Department of Molecular Biology and Genetics (MBG) is situated in Thrace, at the crossroad between Europe and Asia. (europa.eu)
It is the only faculty in Greece providing a curriculum on molecular biology and genetics. (europa.eu)
The Department of Molecular Biology & Genetics (MBG) of Democritus University Thrace set out to take advantage of the specific topics addressed by Activity 4.1 "Unlocking and developing the research potential in the EU's convergence regions and outermost regions" of the FP7-Research Capacities programme-REGPOT-2008-1, towards the convergence with the R&D ranking of EU education and research units of similar size. (europa.eu)

In contradistinction to "classical" diagnostic imaging, molecular imaging probes the molecular abnormalities that are the basis of disease rather than imaging the result of these molecular alterations. (nih.gov)
Where other diagnostic imaging procedures-such as x-rays, computed tomography (CT) and ultrasound-predominantly offer anatomical pictures, molecular imaging allows physicians to see how the body is functioning and to measure its chemical and biological processes. (snmmi.org)
In the study, the researchers used a specialized form of PET imaging called "estrogen receptor expression imaging" for 22 patients with endometrial adenocarcinoma and nine patients with endometrial hyperplasia (a thickening of the uterine lining that is a risk factor for developing endometrial cancer) to evaluate diagnostic accuracy. (brightsurf.com)
Molecular imaging is an emerging diagnostic technology that allows visualization, differentiation, and quantify various biological processes occurring inside a living organism at the molecular and cellular level. (pharmiweb.com)
This rise in the cancer population is leading to a rise in the demand for diagnostic imaging, thereby catalyzing the demand for molecular imaging. (pharmiweb.com)
Renal/bladder ultrasonography improves the diagnostic evaluation and is probably the single best imaging modality to obtain. (medscape.com)
A joint ABR-ABNM task force has released the outline of a so-called dual pathway in which trainees could receive education and certification in both nuclear medicine and diagnostic radiology at the same time, rather than having separate tracks that force imaging specialists to pursue cross-certification on their own. (auntminnie.com)
His research interests include diagnostic imaging, 3D medical image visualization and processing, haemodynamic analysis of cardiovascular diseases and 3D printing in cardiovascular disease. (amj.net.au)
SPECT and PET imaging studies are used in selected difficult cases to improve diagnostic accuracy. (snmjournals.org)
Digital pathology and image analysis are also producing new insights, providing quantitative justification of many existing diagnostic criteria while challenging others. (who.int)
The characteristics of each cancer type, including diagnostic criteria, pathological features, and associated molecular alterations, are described and illustrated in a strictly disease-oriented manner to provide the international standards for diagnosis and cancer research. (who.int)

On August 9th, 2021, the textbook Molecular Imaging: Principles and Practice, 2nd Edition , (Volumes 1 & 2) was published. (stanford.edu)
The Division of Nuclear Medicine and Molecular Imaging held a ribbon cutting ceremony for the new Theragnostics space on May 13, 2021. (stanford.edu)
The global molecular imaging market is estimated to be valued approximately at US$ 4 Bn in 2021, finds Future Market Insights (FMI) in a study. (pharmiweb.com)

While sentinel node biopsy is a routine clinical indication that can benefit from image-guided surgery approaches, it seems imperative that the same technologies should also become available for the visualization of primary tumors and metastases. (lumc.nl)
The FDA has cleared syngo .via VB20 for Molecular Imaging (MI) from Siemens Healthineers-a new release of the company's established intelligent visualization software for multimodality imaging. (24x7mag.com)
Molecular imaging is the visualization, characterization, and measurement of biological processes at the molecular and cellular levels in humans and other living systems. (abnm.org)

The ability to image in vivo the pathological substrates of degenerative diseases and visualize their downstream impact has led to improved models of pathogenesis, better differential diagnosis of atypical conditions, as well as focused subject selection and monitoring of treatment in clinical trials aimed at delaying or preventing the symptomatic phase of Alzheimer's disease. (nih.gov)
Answering to clinical needs in oncology, neurology, cardiology, and radiology, Siemens Healthineers Molecular Imaging systems provide PET/CT, SPECT, and hybrid SPECT scanner (SPECT/CT) solutions to help clinicians diagnose, treat, and monitor diseases more confidently. (siemens-healthineers.com)
Dr. Ulaner not only brings to Hoag enormously valuable standard of care expertise but also multiple innovative clinical trials, including a National Institutes of Health-funded study using molecular imaging to detect cancer at the cellular level. (hoag.org)
Now it turns out Hoag is the first in the nation to use the FES imaging agent in a clinical trial for the staging of breast cancer, and the first in Southern California to offer the agent to sensitively detect breast cancer. (hoag.org)
Besides established functional ultrasound techniques, ultrasound molecular imaging using microbubbles targeted to disease-associated markers is increasingly being applied in pre-clinical studies. (umbjournal.org)
Most notably, it shows how imaging multiple facets of tumor phenotype--in this case, estrogen receptor expression and glucose metabolism--can provide insight into the clinical behavior of cancer. (brightsurf.com)
He gained his M.B and PhD degrees in clinical medicine and medical imaging, respectively, from Harbin Medical University in China and University of Ulster in UK. (amj.net.au)
Thus, further rigorous studies are needed to determine specific clinical applications of MRE for surgical planning, disease monitoring and molecular stratification of brain tumors. (ncigt.org)
Additionally, studies designed to refine existing imaging techniques, or to further develop new techniques to address specific clinical questions, are supported. (dana.org)
The commonly performed studies in routine clinical practice are 99m Tc-labeled brain perfusion radiotracers for SPECT imaging and 18 F-FDG and 18 F-labeled β-amyloid imaging radiotracers for PET imaging ( 2 ). (snmjournals.org)
Multimodality Molecular Imaging of the Cardiovascular System, a supplement to the top-rated Journal of Nuclear Medicine, presents the state of the art of cardiovascular molecular imaging and provides discussion of the opportunities and challenges in advancing cardiovascular molecular imaging to clinical practice. (snmmi.org)
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You can give a free Brain imaging in clinical psychiatry number and be your diseases. (pointsix.com)
To see more about Amazon Sponsored Products, free Brain imaging in clinical certainly. (pointsix.com)
The diagnosis of the clinical conditions of the stomatognathic system is based on two main principles: I) the clinical examination which consists of the physical examination and a careful medical history evaluation and II) the use of complementary examinations to diagnosis (laboratory, imaging, etc. (bvsalud.org)
In this context, the dentist has available numerous tests that help decision making in clinical practice, such as examinations for bi and tri-dimensional images, biochemical tests (blood, saliva or urine) and molecular tests (immunoassay tests to quantitate antigens and antibodies or quantification of bacterial DNA). (bvsalud.org)

Individuals can now be profiled based on their biomarker status for Aβ42 (A) or tau (T) deposition and neurodegeneration (N). The aim of this study was to compare the cerebrospinal fluid (CSF) and imaging (PET/MR) biomarkers in each ATN category and to assess their ability to predict longitudinal cognitive decline. (nature.com)
In longitudinal studies such as this one, it would also be of interest to evaluate ATN profiling based on imaging biomarkers, and further to compare it to profiling with CSF biomarkers. (nature.com)
The Critical Importance of Molecular Biomarkers and Imaging in the Study of Electrohypersensitivity. (emf-portal.org)
Broad molecular profiling systems may be used to simultaneously test for multiple biomarkers. (medscape.com)

Traditionally, cancer classification has been based on consensus of histopathological opinion, with very limited consideration of molecular pathology. (who.int)

Two-step self-assembly of a spider silk molecular clamp, Nature Communications (2018). (phys.org)

To overcome these obstacles, we developed a multimodality imaging platform for discovery-based molecular histology. (vanderbilt.edu)
Multimodality Molecular Imaging of the Cardiovascular. (snmmi.org)

The Revista Española de Medicina Nuclear e Imagen Molecular (Spanish Journal of Nuclear Medicine and Molecular Imaging), was founded in 1982, and is the official journal of the Spanish Society of Nuclear Medicine and Molecular Imaging, which has more than 700 members. (elsevier.es)

Tumor Perfusion with Non-Targeted Microbubbles, Imaged with Nonlinear Contrast and Displayed as MIP. (visualsonics.com)
High-resolution ultrasound (left) and spectrally unmixed photoacoustic (right) image of a subcutaneous tumor showing nanoparticle distribution (yellow) as well as oxygenated (red) and deoxygenated (blue) hemoglobin signal. (visualsonics.com)
3D rendered high-resolution ultrasound (greyscale) and spectrally unmixed photoacoustic (red, blue and gold) image of a subcutaneous tumor showing nanoparticle distribution (yellow) as well as oxygenated (red) and deoxygenated (blue) hemoglobin signal. (visualsonics.com)
Breast Cancer Tumor in a mouse, imaged with photoacoustics in 3D. (visualsonics.com)
Molecular imaging has evolved as a promising tool for early detection of cancers and cardiac diseases, providing a more complete picture of the tumor genome, as well as monitoring tumor emergence during disease. (pharmiweb.com)
MRE is increasingly being examined for potential in brain tumor imaging and might have value for surgical planning. (ncigt.org)

RESEARCH OBJECTIVES Background Current methods for imaging the cardiovascular, pulmonary, and hematopoietic systems, such as CT, MRI, and ultrasound focus predominantly on anatomical and functional measurements. (nih.gov)
The culprit behind the worsening outlook is widely viewed to be the rise of hybrid imaging, as nuclear medicine residents typically lack the training to interpret the anatomical component of hybrid PET/CT, SPECT/CT, or PET/MRI exams. (auntminnie.com)

This initiative seeks to take advantage of the rapid advances that have taken place in imaging technology, allowing normal and pathological processes to be studied in vivo at the molecular and cellular level. (nih.gov)
Molecular imaging is a growing research area aimed at developing and testing novel tools, reagents, and methods to image specific molecular pathways in vivo, particularly those that are key targets in disease processes. (nih.gov)
Molecular imaging can be broadly defined as the in vivo characterization and measurement of biologic processes at the cellular and molecular level. (nih.gov)
The availability of these basic science tools enhances the capacity of molecular imaging to address basic biologic questions in vivo and to do this in a high-throughput fashion. (nih.gov)
This group observed that there was no easily applicable imaging method to assess recovery from stroke and identified the development of in-vivo functional, physiological and/or metabolic markers in the study of brain plasticity as a high priority. (nih.gov)
Research Scope The emerging field of molecular imaging uses novel reagents and methods to image specific cellular and molecular pathways in vivo, particularly those that are key targets in disease processes. (nih.gov)
The ability to obtain molecular information in vivo would help to understand the abnormalities underlying cardiovascular, pulmonary, and blood diseases, would have profound impact on the diagnosis of these conditions, and could provide rapid and efficient assessment of treatment effectiveness. (nih.gov)
An upright laser scanning confocal microscope equipped for high temporal and spatial resolution imaging of fixed cells or tissue sections, as well as live tissue and in vivo intravital techniques. (qmul.ac.uk)
Biodistribution studies in rodents using dissection/gamma counting and in vivo nuclear imaging have been performed. (icmab.es)

Welcome to the Molecular Expressions website featuring our acclaimed photo galleries that explore the fascinating world of optical microscopy. (fsu.edu)
Spinning Disk Confocal Microscopy - Spinning disk microscopy has advanced significantly in the past decade and now represents one of the optimum solutions for both routine and high-performance live-cell imaging applications. (fsu.edu)
The rapid expansion in biomedical research using live-cell imaging techniques over the past several years has been fueled by a combination of events that include dramatic advances in spinning disk confocal microscopy instrumentation coupled with the introduction of novel ultra-sensitive detectors and continued improvements in the performance of genetically-encoded fluorescent proteins. (fsu.edu)
Cleared tissue imaging has emerged as a powerful technique for rendering centimeter sized biological tissues and organs transparent in order to enable three dimensional volume imaging via light microscopy. (harvard.edu)
CLARITY also maintains fluorescent protein emission, and a number of microscopy manufacturers now produce high resolution objective lenses designed specifically for imaging CLARITY samples. (harvard.edu)
K hler Microscope Illumination - Illumination of the specimen is the most important variable in achieving high-quality images in microscopy and critical photomicrography. (fsu.edu)

Molecular imaging techniques using 18 F-fluorodeoxyglucose, amyloid tracers, and, more recently, tau ligands have taken dementia research by storm and undoubtedly improved our understanding of neurodegenerative diseases. (nih.gov)
PET imaging and emerging immunotherapy candidates are beginning to enable image-based therapy personalization for dementia. (siemens-healthineers.com)
In this pictorial review article, we will discuss the current status of 18 F-FDG PET brain imaging in patients with dementia and present figures and semiquantitative analysis results of various subtypes of dementias as well as certain artifacts seen on 18 F-FDG PET brain imaging studies. (snmjournals.org)

With more than 47 locations around the globe, Siemens Healthineers PETNET Solutions is the largest supplier of positron emission tomography (PET) radiopharmaceuticals, delivering more than 1,000,000 doses to more than 2,800 imaging centers worldwide, each year. (siemens-healthineers.com)
The method of positron emission tomography (PET) imaging we used in the study is noninvasive, and it has tremendous potential to save women with endometrial carcinoma from undergoing unnecessary operations and biopsies that could sabotage their reproductive potential. (brightsurf.com)
On August 5, UC Davis veterinary radiologist Dr. Mathieu Spriet presented "New Equine Imaging Options with Standing PET at UC Davis," an informative webinar to update veterinarians on the latest in positron emission tomography (PET) for horses. (ucdavis.edu)
Standing equine positron emission tomography (PET) imaging is not just for racehorses anymore. (ucdavis.edu)
The UC Davis standing equine positron emission tomography (PET) scanner is officially in use at Golden Gate Fields racetrack in Berkeley, CA, providing imaging at the molecular level to monitor racehorse health and guide training and medical care. (ucdavis.edu)

Molecular imaging targets molecular pathways and mechanisms associated with a particular disease present inside a living body. (pharmiweb.com)
Our results offer molecular insight into the mechanisms of synaptic plasticity. (eneuro.org)
As a consequence, considerable efforts have been undertaken to identify biologic mechanisms of atherosclerotic lesions by use of molecular-targeted radiolabeled probes. (elsevier.com)
During day one of the workshop attendees were introduced to the basic concepts of light scatter in biological tissues, the molecular mechanisms behind a number of tissue clearing techniques, and proper sample preparation. (harvard.edu)
Its mission is to promote excellence in research in the Chemical Sciences, by elucidating and controlling molecular mechanisms, developing new fundamental theories, and meeting the evolving technological needs of our society through the design and synthesis of new molecular systems and devices. (uc.pt)

The basic approach for evaluating patients with cognitive dysfunction includes detailed history, physical and neurologic examination, cognitive testing, laboratory testing, specialty consultation, and routine brain imaging with CT or MRI to identify structural, demyelinating, inflammatory, or vascular etiologies ( 1 ). (snmjournals.org)

In this article, we present the main molecular imaging techniques used in research and practice. (nih.gov)
Molecular Imaging: Principles and Practice, Volumes 1 and 2, Second Edition provides the first point of entry for physicians, scientists, and practitioners. (stanford.edu)
Thermodynamics Based on Molecular Image: Exploration and Practice of Physical Chemistry Teaching[J].University Chemistry, 2020, 35(3): 120-127. (pku.edu.cn)

Molecular imaging excels at detecting the cellular changes that occur early in the course of disease, often well before structural changes can be seen on CT and MR images. (snmmi.org)
2013). Structural and molecular interrogation of intact biological systems. (harvard.edu)
Today, it is possible to manufacture artificial spider silk of similar properties as the prototype, but the molecular-level structural details responsible for material properties await to be disclosed. (phys.org)
Despite many advances in understanding the pathophysiology of Mn neurotoxicity in humans, with molecular and structural imaging techniques, only a few case reports describe the associated pathological findings, and all are in symptomatic subjects exposed to relatively high-level Mn. (cdc.gov)

With cryoEM images providing a road map, the Nair Lab carried out biochemical studies to pinpoint the active site elements that enabled the unusual peptide cutting activity in ribosomal peptide biosynthesis. (illinois.edu)

The first goal is to detect and quantify at the molecular and cellular level the cellular pathways that regulate heart, lung and blood function, and the abnormalities in these pathways occurring in heart, lung, blood and sleep disorders. (nih.gov)
The full potential for molecular and cellular imaging has not yet been realized for imaging heart, lung, and blood. (nih.gov)
While there has been limited use of imaging techniques that may be defined as "molecular" for imaging heart, lung, and blood,(e.g., imaging with monoclonal antibodies or receptor imaging with nuclear techniques), it is only recently that needed adjunct basic research tools have become routinely available. (nih.gov)
Molecular imaging is playing an increasingly important role in the detection, diagnosis and treatment of NSCLC, which accounts for the majority of lung cancer cases. (snmmi.org)
What is molecular imaging and how does it help people with lung cancer? (snmmi.org)
What molecular imaging technologies are used for lung cancer? (snmmi.org)
2020). A molecular map of lung neuroendocrine neoplasms. (who.int)

Here we applied new technologies associated with advances in molecular imaging to demonstrate the feasibility of labeling primary immune cells. (rsc.org)

Here, fluorescence imaging in particular can be used to intraoperatively define margins. (lumc.nl)
c-Met targeted fluorescence imaging. (lumc.nl)
This upright microscope enables brightfield, DIC and fluorescence imaging applications with fixed and live samples. (qmul.ac.uk)
Here, we combine 12-color multiplexed fluorescence imaging with quantitative image analysis and machine learning to identify novel synaptic subtypes within excitatory and inhibitory synapses based on the expression profiles of major synaptic components. (eneuro.org)
In this work, we use multiplexed fluorescence imaging with advanced image analysis to detect and quantify protein levels using CellProfiler. (eneuro.org)

Often, repeated injections of non-targeted or targeted microbubbles during the same imaging session are administered. (umbjournal.org)
Mouse Kidney Perfusion with Non-Targerted Microbubbles Imaged in Nonlinear Contrast Mode. (visualsonics.com)

These data provide an unbiased, three-dimensional analysis of how disease affects the molecular architecture of complex tissues, enable culture-free diagnosis of infection through imaging-based detection of bacterial and host analytes, and reveal molecular heterogeneity at the host-pathogen interface. (vanderbilt.edu)
18 F-FDG PET brain imaging is commonly used in the early detection and differential diagnosis of various subtypes of dementias. (snmjournals.org)
Thyroid imaging and radiotracer thyroid uptake measurements, combined with serologic data, enable specific diagnosis and appropriate patient treatment. (medscape.com)

BACKGROUND AND PURPOSE: Functional magnetic resonance imaging (fMRI) is becoming widely recognized as a key component of preoperative neurosurgical planning, although intraoperative electrocortical stimulation (ECS) is considered the gold standard surgical brain mapping method. (ncigt.org)
The 2017 guidelines from the European Society of Cardiology (ESC) and the European Society of Vascular Surgery (ESVS) noted that CT angiography (CTA) is an excellent imaging tool for supra-aortic lesions and that magnetic resonance angiography (MRA) provides functional and morphologic information useful for distinguishing anterograde from retrograde perfusion and estimating stenosis severity. (medscape.com)

Here, we strongly focus on a multimodal/hybrid guidance concept whereby pre- and intra-operative imaging information is integrated to provide optimal sensitivity and specificity. (lumc.nl)
In particular their ability to integrate pre- and intra-operative imaging findings can be considered highly advantageous. (lumc.nl)

This acquisition enhances Bruker's offering in targeted multi-omics and fluorescence-based imaging techniques. (pharmiweb.com)

Endometrial carcinoma is one of the most common female malignant tumors," says Hidehiko Okazawa, M.D., Ph.D., professor in the division of medical imaging at the biomedical imaging research center at the University of Fukui in Japan and one of the lead researchers of the study. (brightsurf.com)

Molecular imaging procedures are noninvasive, safe and painless. (snmmi.org)
Reston, Va.--A promising new molecular imaging technique may provide physicians and patients with a noninvasive way to learn more information about a type of cancer of the uterus lining called "endometrial carcinoma"--one of the most common malignant female tumors. (brightsurf.com)
Indocyanine green fluorescent imaging has been described as a noninvasive means of characterizing and quantifying microcirculatory disorders in patients with peripheral arterial occlusive disease of the upper extremity. (medscape.com)

It also synthesizes radiopharmaceuticals and new chemical entities for medical imaging with continuous flow techniques. (uc.pt)

The Society of Nuclear Medicine and Molecular Imaging (SNMMI) has named Stanford Health Care and the Dana-Farber Brigham Cancer Center as its first two designated Radiopharmaceutical Therapy Centers of Excellence. (stanford.edu)
To know the current status of the technique of radioguided localisation of non-palpable breast lesions with or without indication for selective sentinel node biopsy -ROLL, SNOLL and 125 I seeds- by conducting a national survey developed by the Working Group on Radioguided Surgery (GTCRG) of the Spanish Society of Nuclear Medicine and Molecular Imaging (SEMNIM). (elsevier.es)
The announcement of the bill has been met with a flurry of support within the medical imaging community, including by Society of Nuclear Medicine and Molecular Imaging (SNMMI), which plans to start a letter-writing campaign upon introduction of the bill and is asking patients and the nuclear medicine and molecular imaging community to participate in it. (dotmed.com)
In terms of response, many questions have already been raised about how the actions could affect nuclear medicine and molecular imaging going forward. (auntminnie.com)

Learn more about molecular testing in NSCLC. (medscape.com)

Conventional imaging is suboptimal in evaluating disease status in renal cell carcinoma (RCC) due to its poor sensitivity. (medscape.com)
Development of new molecular probes for conventional imaging techniques such as MRI and ultrasound, and application of new technologies such as optical imaging show great promise, but their use in the cardiovascular, pulmonary, and hematopoietic systems is still limited. (nih.gov)
Conventional imaging is suboptimal at evaluating disease status in renal cell carcinoma (RCC) because of poor sensitivity. (medscape.com)
Scientists, using either conventional brain imaging techniques, cellular and molecular imaging technologies, or a combination of both, are supported to undertake pilot tests of novel hypotheses. (dana.org)
In conventional surgery, a pre-surgical magnetic resonance imaging (MRI) picture of the patient's brain is loaded into a neuronavigation machine, which guides the surgeon during the operation. (embs.org)

Molecular imaging offers unique insights into the human body that enable physicians to personalize patient care. (snmmi.org)
Not only do our insights rationalise the emergence of polarisation in previously studied materials, but we identify the fundamental importance of molecular degrees of freedom that are straightforwardly controlled from a synthetic viewpoint. (nature.com)

One of the world's leading research institutes, our scientists are working to advance understanding of biological processes at the molecular level - providing the knowledge needed to solve key problems in human health. (cam.ac.uk)

Published molecular imaging applications using the Vevo systems include biomarker quantification, monitoring drug delivery, cell tracking, diagnostics such as detection of metastatic cells, development and characterization of novel theranostic contrast agents. (visualsonics.com)
Adequate characterization of suspect lesions based on imaging is essential to avoid invasive biopsies and superfluous surgery, both in localized and advanced disease. (medscape.com)
The unit operates as internal and external (from mid 2011) service providing advanced cellular imaging and characterization of in vitro macromolecular and target-drug interactions with support from dedicated scientific staff of international expertise. (europa.eu)

Host-guest interactions of curcubiturils with fluorescent probes, photoCORMs, TTA-UC molecular systems, Au(I) - coumarin complexes, supramolecular chemosensors, and ligands aiming to to inhibit DNA telomerase in cancer cells are also being explored. (uc.pt)

In nuclear medicine, which is a branch of molecular imaging, the imaging agent is a radiotracer, a compound that includes a radioactive atom, or isotope. (snmmi.org)

Magnetic resonance (MR) spectroscopy is able to measure chemical levels in the body, without the use of an imaging agent. (snmmi.org)

Fluorescent Protein Technology - It took over thirty years, and the advent of recombinant DNA as well as vastly improved molecular biological approaches to see the pioneering work of Osamu Shimomura developed into a useful tool for live-cell imaging by Doug Prasher and Martin Chalfie. (fsu.edu)
Continued efforts using directed evolution approaches will no doubt improve the spectral characteristics, photostability, maturation time, brightness, acid resistance, and utility of the fluorescent protein tags for cellular imaging. (fsu.edu)

Among the research initiatives include the use of molecular imaging in breast cancer using a novel molecular imaging agent for the detection of estrogen receptor-positive lesions in patients with recurrent or metastatic breast cancer. (hoag.org)

For this reason, radionuclide imaging and radionuclide therapy are extensively investigated. (medscape.com)
This review provides an overview of the current progress in molecular imaging and radionuclide therapy in clear cell RCC and will focus on promising detection and therapy strategies targeting the carbonic anhydrase IX antigen, which is expressed in clear cell RCC. (medscape.com)
This review summarizes the current knowledge on radionuclide imaging of RCC, as well as the experience gained in radioimmunotherapy (RIT) trials in these patients. (medscape.com)
This special issue of The Journal of Nuclear Medicine addresses the current state of and developments in radionuclide imaging as well as limitations, threats, and possible solutions. (snmmi.org)

Computer generated molecular model of an HIV protein. (scienceimage.csiro.au)
Scientists from the University of Würzburg discovered new molecular details of self-assembly of a spider silk fibre protein. (phys.org)
The molecular interaction between hemoglobin (HHb), the major human heme protein, and the acridine dyes acridine orange (AO) and 9-aminoacridine (9AA) was studied by various spectroscopic, calorimetric and molecular modeling techniques. (jascoinc.com)

Also in 2001, the ICRH/Heart and Stroke Foundation sponsored the Canadian Consensus Conference on Acute Stroke Imaging of Thrombolytic Therapy. (nih.gov)
Hoag Memorial Hospital Presbyterian is on the move, building what will become an elite Molecular Imaging and Therapy program. (hoag.org)
Using molecular imaging to target cancer cells, Dr. Ulaner will also lead trials investigating the efficacy of targeted radiation therapy known as liquid radiation to treat cancer. (hoag.org)
Hoag's Molecular Imaging and Therapy Program is helping to pioneer the most sensitive imaging methods to date to advance research and more superiorly, treat Hoag cancer patients. (hoag.org)
This study shows that PET is a promising molecular imaging technique for personalized therapy. (brightsurf.com)
Alongside, models are developed and tested in order to understand and predict phenomena subsequent to light absorption, covering a wide variety of processes such as molecular reactivity, the responses of the immune system, drug-delivery and gene therapy. (uc.pt)

You may be hearing about a new breast cancer screening test for women with dense breast tissue called molecular breast imaging or MBI. (mayoclinichealthsystem.org)
Molecular clouds, dense and compact regions throughout the Milky Way where gas and dust clump together, represent one of the sources of foreground emission seen by Planck. (esa.int)

MBG excels in basic research, answering key biological questions with application in understanding the molecular basis of human diseases. (europa.eu)

The need for improved molecular and cellular imaging techniques was a common thread running through recommendations from several of the subgroups of the January 2003 NHLBI Spark II Conference ( http://www.nhlbi.nih.gov/funding/fromdir/spark2web.htm ). (nih.gov)
Molecular imaging provides the ability to accurately evaluate biological responses to the treatment of individual patients over time, opening the door to personalized medical techniques directed by molecular imaging reporters. (pharmiweb.com)
Examination of the entire molecular composition of individual synapses using techniques that can survey the entire proteome, such as mass spectrometry, would be ideal for characterizing synapses. (eneuro.org)

Unfortunately, the current solvents used in the process can quench the native emission of fluorescent proteins and are incompatible with high-resolution microscope objectives that "dip" into the mounting solution during imaging. (harvard.edu)

Molecular subtypes of pulmonary large-cell neuroendocrine carcinoma predict chemotherapy treatment outcome. (who.int)

Nuclear medicine plays a vital role in conducting a molecular imaging process and can be broadly used for the treatment of distinct cancer and related diseases. (pharmiweb.com)
Diseases are characterized by distinct changes in tissue molecular distribution. (vanderbilt.edu)

PETNET Solutions is making strides in its mission to bring the power of PET to imaging centers with a new Chicago radiopharmacy. (siemens-healthineers.com)
18 F-FDG PET images are mainly evaluated visually, and semiquantitative analysis programs are also commonly used in many centers. (snmjournals.org)
15 O-water brain perfusion and 15 O PET imaging studies are available only in limited centers ( 4 ). (snmjournals.org)

This Olympus iX81 is an inverted, fully motorised and environment-controlled microscope for brightfield, phase contrast and epifluorescence imaging applications, suited to live and fixed samples on slides, 35 mm dishes or multi-well plates. (qmul.ac.uk)
Contrast Media Mol Imaging. (bvs.br)
FIRST (Fibered Imager foR a Single Telescope) is a post-extreme AO instrument module undergoing commissioning at the Subaru Telescope that enables high-contrast imaging at sub-diffraction limit spatial scales. (obspm.fr)

Subtypes of dementias usually show characteristic findings on 18 F-FDG PET images ( 8 - 13 ). (snmjournals.org)

In the present study, the principal investigator investigates the use of molecular imaging to improve precision-based detection methods, leading to superior treatment outcomes. (hoag.org)
It enables to study of the molecular abnormalities taking place inside the body to carry out early detection of disease and to optimize medications aiming for disease-related molecular targets. (pharmiweb.com)

Modalities5

20221

Biology8

Diagnostic11

20213

Visualization3

Clinical16

Biomarkers4

Pathology1

20181

Multimodality2

Imagen Molecular1

Tumor6

Anatomical2

Vivo9

Microscopy6

Dementia3

Positron emission t5

Mechanisms5

Laboratory1

Practice3

Structural4

Biochemical1

Lung7

Advances1

Fluorescence Imaging5

Microbubbles2

Diagnosis3

Functional2

Intra-operative2

Multi-omics1

Biomedical1

Noninvasive3

Radiopharmaceuticals1

Nuclear medicine and molecular4

NSCLC1

Conventional5

Insights2

Biological processes at the molecular1

Characterization3

Probes1

Radiotracer1

Magnetic1

Approaches2

Lesions1

Radionuclide4

Protein3

Therapy6

Dense2

Excels1

Techniques3

Fluorescent1

Pulmonary1

Diseases2

Centers3

Contrast3

Subtypes1

Detection2