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  • chromosomes
  • Panicle length (PL) is an important trait for improving panicle architecture and grain yield in rice ( Oryza sativa L.). Three populations were used to identify QTLs and candidate genes associated with PL. Four QTLs for PL were detected on chromosomes 4, 6, and 9 through linkage mapping in the recombinant inbred line population derived from a cross between the cultivars Xiushui79 (short panicle) and C-bao (long panicle). (frontiersin.org)
  • Mutations
  • We aimed to assess long-term outcomes of bariatric operations in patients characterized for eating behavior and rare mutations in the melanocortin-4 receptor ( MC4R ) gene, which is strongly implicated in energy balance. (diabetesjournals.org)
  • We and others previously described associations between disordered eating and mutations in the melanocortin-4 receptor ( MC4R ) gene ( 8 , 9 ), the most common cause of monogenic obesity in Europeans. (diabetesjournals.org)
  • OBJECTIVE: To perform a molecular autopsy Involving the RyR2-encoded cardiac ryanodine receptor/calcium release channel to determine whether mutations responsible for catecholaminergic polymorphic ventricular tachycardla (CPVT) represent a novel pathogenic basis for unexplained drownings. (ebscohost.com)
  • CONCLUSIONS: This molecular autopsy study provides proof of principle that RyR2 mutations can underlie some unexplained drownings. (ebscohost.com)
  • Objective: To determine the presence of exon 20 to 22 (pocket B E1A Domain) mutations of RB1 gene and their clinical presentation in Malaysian children with retinoblastoma. (ebscohost.com)
  • Background: Familial Adenomatous Polyposis (FAP) is caused by germline mutations in the APC (Adenomatous Polyposis Coli) gene. (ebscohost.com)
  • Introduction: Mutations of the von Hippel-Lindau (VHL) gene are responsible for VHL disease. (ebscohost.com)
  • Analysis of haemochromatosis gene mutations in a population from the Mediterranean Basin. (semanticscholar.org)
  • Frequency and biochemical expression of C282Y/H63D hemochromatosis (HFE) gene mutations in the healthy adult population in Italy. (semanticscholar.org)
  • Spectrum of mutations in the HFE gene implicated in haemochromatosis and porphyria. (semanticscholar.org)
  • A reverse-hybridization assay for the rapid and simultaneous detection of nine HFE gene mutations. (semanticscholar.org)
  • mutational
  • This suggests the types and frequencies, or mutational space, of a majority of amino acid changes sampled by the SHM machinery to be well captured by GSSPs. (frontiersin.org)
  • GSSPs can also be used for predicting the amino acid mutational space available for antigen-driven selection and for understanding factors modulating the maturation pathways of antibody lineages in a gene-specific context. (frontiersin.org)
  • clone
  • I am a good scientific researcher and have many technical skills in gentransformation, molecular analysis, gene clone, protein purification, DNA and RNA preparation, protoplast fusion, plant cell and tissue culture, etc. (bio.net)
  • 1997
  • The F statistic is a measure of the difference between the mean heterozygosity among the subdivisions in a population, and the potential frequency of heterozygotes if all members of the population mixed freely and non-assortatively (Hartl and Clark 1997). (sfsu.edu)
  • protein
  • Molecular analysis showed that rabbit NP-1 gene has been intergrated and transcribed in C.ellipsoidea and expressed its protein product property. (bio.net)
  • bidirectional
  • Our microsatellite data showed that (1) the process of Africanization involved both maternal and paternal bidirectional gene flow between European and Africanized honeybees and (2) the panmitic European population was replaced by panmitic mixtures of A. m. scutellata and European genes within 5 years after Africanization. (genetics.org)
  • high
  • Taken together, we believe that thymidine may be used in a therapeutic fashion to enable the maintenance of high levels of treated cells bearing repaired genes. (biomedcentral.com)
  • This is consistent with self-incompatibility in the group and high gene flow within species. (springer.com)
  • My Ph.D dissertation is about establishment of high frequency gene transformation system and expression of defensin(NP-1) gene in unicelluar green alga(Chlorella ellipsoida). (bio.net)
  • Now, high frequency foreign gene transformation system of C.ellipsoidea has been establish. (bio.net)
  • absence
  • AMOVA treats any kind of raw molecular data as a Boolean vector p i , that is, a 1 n matrix of 1s and 0s, 1 indicating the presence of a marker and 0 its absence. (sfsu.edu)
  • crossovers
  • Crossovers were restored to wild-type frequency in the double mutant mlh3 Δ pch2 Δ (100 crossovers per meiosis), but obligate crossovers were compromised. (g3journal.org)
  • This gene is located about a quarter of the distance from the pericentric heterochromatin of the X to the telomere, a region where crossovers are relatively infrequent. (g3journal.org)
  • primary
  • Observed remobilization frequencies of primary, secondary, tertiary, and quaternary TNPs, coupled with the tendency for localized Ds transposition, validates a saturation mutagenesis approach using Ds to tag and characterize genes linked to Ds in large genome cereals like barley and wheat. (deepdyve.com)
  • organisms
  • The glutathione S-transferase (GST) gene family is involved in the detoxification of electrophilic compounds by conjugation, and in higher organisms at least five GSTs gene classes ( alpha, mu, pi, theta and zeta ) have been well studied. (scielo.br)
  • cells
  • Despite success with the technique, recent studies have revealed that following repair events, correction frequencies decrease as a function of time, possibly due to a sustained activation of damage response signals in corrected cells that lead to a selective stalling. (biomedcentral.com)
  • Next, we devised a protocol in which cells are maintained in thymidine following the repair reaction, in which the replication is slowed in both corrected and non-corrected cells and the initial correction frequency is retained. (biomedcentral.com)
  • Using time-lapse microscopy, we found that Crz1 exhibited short bursts of nuclear localization (~2 minutes) that occurred stochastically in individual cells and propagated to the expression of downstream genes. (pubmedcentralcanada.ca)
  • Cells sense extracellular signals and respond by regulating the expression of target genes 1 , 2 , 3 . (pubmedcentralcanada.ca)
  • Cell
  • These results suggest that FM regulation of localization bursts may be a general control strategy utilized by the cell to coordinate multi-gene responses to external signals. (pubmedcentralcanada.ca)
  • Journal
  • P. Farnia, J. Ghanavi, P. Tabasri, S. Saif, and A. A. Velayati, "The importance of single nucleotide polymorphisms in interferon gamma receptor-1 gene in pulmonary patients infected with rapid grower mycobacterium," International Journal of Mycobacteriology , vol. 5, Supplement 1, pp. (hindawi.com)
  • years
  • This is evidence of a molecular clock-a roughly constant rate of evolutionary change for every lineage over a period of hundreds of millions of years. (blogspot.com)
  • however
  • The role of replication in the gene repair reaction, however, has recently been met with a paradoxical series of events. (biomedcentral.com)