• To investigate the value of fluorescence in situ hybridization (FISH) in the diagnosis and prognosis evaluation of patients with chronic lymphocytic leukemia (CLL). (nih.gov)
  • 1986) developed fluorescence in situ hybridization (FISH). (medscape.com)
  • It includes a series of techniques referred to as fluorescence in situ hybridization, or FISH, in which DNA probes are labeled with different colored fluorescent tags to visualize one or more specific regions of the genome. (wikipedia.org)
  • Comparative genomic hybridization (CGH), derived from FISH, is used to compare variations in copy number between a biological sample and a reference. (wikipedia.org)
  • Clinical assessments, and cytogenetic, array CGH and fluorescence in situ hybridisation (FISH) analyses were performed. (bmj.com)
  • The global fluorescence in-situ hybridization (FISH) imaging systems market growth is influenced by rising prevalence of target disorders and the increasing R&D investments in in-vitro diagnostics. (benzinga.com)
  • FISH is a powerful molecular cytogenetic technique that allows the visualization and localization of specific DNA sequences within cells or tissues. (benzinga.com)
  • These companies adopt product innovation strategies to meet evolving customer demands, which allows them to maintain their brand name in the fluorescence in-situ hybridization (FISH) imaging systems market. (benzinga.com)
  • Diagnosis is made by confirming a deletion in the WHS critical region (WHSCR) using conventional chromosome analysis, fluorescence in situ hybridization (FISH), or chromosomal microarray. (medscape.com)
  • Em ambos os grupos foram realizados hemograma completo, teste do micronúcleo em linfócitos com bloqueio da citocinese (CBMN), teste de FISH em linfócitos para a translocação t(15;17), bem como testes moleculares para avaliação de polimorfismos em genes envolvidos na metabolização do benzeno (MPO, NQO1, CYP1A1 e CYP2E1) e na eliminação de xenobióticos (GSTM1/GSTT1). (usp.br)
  • In both groups were performed blood cell counts, cytokinesis-block micronucleus assay (CBMN), FISH assay in peripheral blood lymphocytes for translocation t(15;17), and molecular tests for evaluation of genetic polymorphisms in genes involved in benzene metabolism (MPO, NQO1, CYP1A1 e CYP2E1) and detoxification (GSTM1/GSTT1). (usp.br)
  • In addition to morphologic assessment (blood and BM), obtain sufficient samples and perform conventional cytogenetic analysis (ie, karyotype), appropriate molecular-genetic and/or fluorescence in situ hybridization (FISH) testing, and flow cytometry immunophenotyping (FCIp). (medscape.com)
  • Molecular genetic and/or FISH testing does not, however, replace conventional cytogenetic analysis. (medscape.com)
  • Fluorescence in-situ hybridization (FISH) is a type of molecular cytogenetic testing that is used to assess constitutional and acquired chromosomal aberrations by detecting the presence or absence (also referred to as copy number changes), and relative positioning of specific genes by fluorescence microscopy. (enzolifesciences.com)
  • Microarray comparative genomic hybridization (aCGH) testing is utilized for the detection of genetic imbalances caused by gain or loss of chromosomal material (copy number changes), which may be beyond the detectable range of conventional cytogenetic and FISH techniques. (enzolifesciences.com)
  • As pioneers in labeling and detection, we have used our superior labeling technology at Enzo to develop a broad range of molecular tools for the cytogenetics market, including FISH and array CGH solutions. (enzolifesciences.com)
  • When coupled with the Nick Translation DNA Labeling System, this direct approach provides a simple and efficient method to label DNA for FISH, suitable for a wide range of molecular biology and cytogenetics applications. (enzolifesciences.com)
  • The introduction of FISH (fluorescence in situ hybridization) marked the beginning of a new era for the study of chromosome structure and function. (biosyn.com)
  • The diversification of the original FISH protocol into the impressive number of procedures available these days has been promoted throughout the years by a number of interconnected factors: the improvement in sensitivity, specificity and resolution, together with the advances in the fields of fluorescence microscopy and digital imaging, and the growing availability of genomic and bioinformatic resources. (biosyn.com)
  • These analyses employ standard cytogenetic and fluorescence in situ hybridisation (FISH), array-based profiling, and flow cytometric isolation and massively parallel sequencing of WDLPS NCs, complemented by transcriptome sequencing. (sarcomahelp.org)
  • Fluorescence in situ hybridization (FISH) is a molecular cytogenetic technique. (keldysh.ru)
  • both fluorescence in situ hybridization (FISH) and the polymerase chain reaction (PCR) shown the presence of SRY gene. (longdom.org)
  • Tests known as FISH (fluorescence in situ hybridisation), PCR (polymerase chain reaction) and NGS (next generation sequencing) are used to look for the most common gene changes in AML. (cancercouncil.com.au)
  • Spermatocyte chromosomes of Melarhaphe neritoides (Mollusca, Prosobranchia, Caenogastropoda) were studied using fluorescent in situ hybridization (FISH) with four repetitive DNA probes (18S rDNA, 5S rDNA, (TTAGGG) n and (GATA) n ). (nature.com)
  • Fluorescence in situ hybridization (FISH) is a powerful technique enabling the visualization of nucleic acid probes on target chromosomes, nuclei, cells and tissues. (nature.com)
  • The lab also performs fluorescence in-situ hybridization (FISH) analysis to detect targeted chromosome abnormalities. (metropolisindia.com)
  • Cytogenetics is the branch of genetics that studies the structure of DNA within the cell nucleus in order to derive the relationship between chromosomal aberrations and genetic diseases in human beings using traditional Karyotyping and FISH techniques to more advances molecular cytogenetics. (meditest.co.in)
  • Prenatal molecular cytogenetic tests include rapid aneuploidy detection (24-48 hours) of chromosomes 13, 18, 21, X, and Y by fluorescence in situ hybridization (FISH). (meditest.co.in)
  • It is demonstrated that, in addition to routine staining and other traditional techniques of chromosome research, karyotypes of an increasing number of hymenopterans are being studied using molecular methods, e.g., staining with base-specific fluorochromes and fluorescence in situ hybridization (FISH), including microdissection and chromosome painting. (journaltocs.ac.uk)
  • It was aimed to analyse the chromosome content of MN in Fragile X cells during folate deprivation by the MN-fluorescence in situ hybridization (FISH) method. (genome-integrity.org)
  • For future analyses of X-inactivation by molecular-cytogenetic techniques we propose to use two-color FISH: an alphoid DNA probe will be used in order to differenti-ate the parental origin of chromosome X by one color, and the XIST RNA probe will mark the active/inactive chro-mosome X by another color. (edu.mk)
  • The use of original DNA probes and FISH as a base for a molecular-cytogenetic X-inactivation assay is appli-cable for further investigation and dissection of XLMR among the heterogeneous group of idiopathic mental retar-dation. (edu.mk)
  • Here we report on two patients with secondary infertility whose karyotype revealed mosaic partially cryptic CCRs, revealed by fluorescence in situ hybridization (FISH). (canceropole-est.org)
  • Modern cytogenetic examination methods such as fluorescence-in-situ-hybridization (FISH-analysis) and comparative genomic hybridization using array-comparative genomic hybridization (Array-CGH, molecular karyotyping) allow high-resolution studies of the entire genome for chromosomal aberrations. (urology-textbook.com)
  • We report the characterization, by reverse fluorescence in situ hybridization (FISH), of 59 hybrids retaining fragments of human chromosome 5. (uniba.it)
  • As an additional resource for cytogenetic studies involving chromosome 5, we report the characterization, by FISH, of 73 YACs from CEPH. (uniba.it)
  • There are other informative tests, such as the comprehensive cytogenetics, which is often sent off of the bone marrow aspirate, as well as the FISH [fluorescence in situ hybridization] test to look for cytogenetic changes. (targetedonc.com)
  • The Tumor Genetics Program, Cancer Genetics Branch, Division of Cancer Biology (DCB), National Cancer Institute (NCI) invites applications for research projects to generate a resource of mapped human large-insert Bacterial Artificial Chromosomes (BAC) clones that can be used for fluorescence in situ hybridization (FISH) mapping studies, with a resolution of approximately 1 megabasepair, which is equivalent to 3,000-5,000 BAC clones for the whole human genome. (nih.gov)
  • Une quantification par cytométrie en flux trois couleurs des cellules CD34+/Annexine+/PI, une analyse FISH, un marquage immunocytochimique des préparations cytospines de la moelle osseuse et des cultures de cellules souches à long terme ont été réalisés. (who.int)
  • By comparing the fluorescence in a sample compared to a reference, CGH can point to gains or losses of chromosomal regions. (wikipedia.org)
  • To provide more insights into the genetic variation within EAHBs, genotyping using simple sequence repeat (SSR) markers, molecular analysis of ITS1-5.8S-ITS2 region of ribosomal DNA locus, and the analysis of chromosomal distribution of ribosomal DNA sequences were done. (cas.cz)
  • Cytogenetic microarray testing can be utilized during pregnancy to aid physicians in determining whether a fetus or newborn has chromosomal anomalies or developmental delays. (enzolifesciences.com)
  • Array-based comparative genomic hybridization (aCGH) is a powerful tool for detecting gene copy number gains and losses associated with chromosomal abnormalities. (enzolifesciences.com)
  • As a combined molecular and cytological approach, the major advantage of this visually appealing technique resides in its unique ability to provide an intermediate degree of resolution between DNA analysis and chromosomal investigations while retaining information at the single-cell level. (biosyn.com)
  • Riegel M, Barcellos N, Mergener R, Silva de Souza KR, Loguercio Leite JC, Gus R, Azevedo Moreira LM, Giugliani R. Molecular cytogenetic evaluation of chromosomal microdeletions: the experience of a public hospital in Southern Brazil. (ufrgs.br)
  • Summary Interphase fluorescence in situ hybridization (iFISH) was used independently to reveal chromosomal abnormalities of prognostic importance in a large, consecutive series of children (n = 2367) with acute lymphoblastic leukaemia (ALL). (birmingham.ac.uk)
  • CML is one of the most extensively studied human malignancies and was the first example of a disease, where the underlying molecular basis was a consistent chromosomal abnormality, the Philadelphia chromosome (Ph), that is the product of a balanced reciprocal translocation involving chromosomes 9 and 22. (biomedcentral.com)
  • Then the correlation of the molecular cytogenetic abnormalities with the clinical Binet stages, Rai stages and the other related laboratory examinations was analyzed. (nih.gov)
  • Clinical indicators for cytogenetic evaluation, cytogenetic techniques, and clinical applications will be discussed. (medscape.com)
  • A complete diagnosis of acute leukemia (AL) requires knowledge of clinical information combined with morphologic evaluation, immunophenotyping and karyotype analysis, and, often, molecular genetic testing. (medscape.com)
  • Our study reinforces the idea that the effort to improve the capacity to perform molecular cytogenetic investigations associated with a qualified clinical evaluation is crucial for the detection and precise characterization of submicroscopic chromosome deletions, bringing benefits to patients, relatives, and genetic counselors. (ufrgs.br)
  • The importance of molecular genetic studies in the isolation of myeloid and histiocytic neoplasms and the need to apply these studies in clinical practice are emphasized. (bvsalud.org)
  • Methods: Clinical examination, conventional cytogenetic analysis, fluorescence insitu hybridization and molecular genetic analysis polymerease chain reaction were done on a 17 year old female patient. (longdom.org)
  • The clinical presentation, pathologic features, and cytogenetic profile were similar to de novo CML. (medscape.com)
  • Therapy-related CML has a clinical presentation, pathologic features, and cytogenetic profile akin to de novo CML. (medscape.com)
  • It is a rapidly growing area of medicine that combines elements of genetics, molecular biology, and clinical medicine to study the impact of genes on human health. (paramedicalcourses.co.in)
  • With the recent advances in molecular genetics and the availability of genetic maps, we have witnessed the emergence of genomics into clinical veterinary practice. (vin.com)
  • There is growing appreciation of the clinical usefulness of the identification of a recurring chromosome abnormality, by cytogenetic or molecular means, in the diagnosis, subclassification and prognosis of a neoplastic disorder, and, hence, in the selection of the appropriate treatment. (nih.gov)
  • ABSTRACT This study examined haematopoietic stem cells of 19 high-risk cases of myelodysplastic syndrome (MDS) for apoptotic and anti-apoptotic signals and cellular proliferation and correlated these with clinical and cytogenetic subtypes, particularly trisomy 8. (who.int)
  • This review will provide nurses with a basic background in genetics, which will enable them to assist children and their families who are affected by a genetic disorder or who are considering cytogenetic testing. (medscape.com)
  • Given the explosive developments in molecular genetics during the past decade, it is certain that families of this type will provide important clues to the etiology, pathogenesis, and ultimate prevention of CLL. (nih.gov)
  • Since then, advancements in molecular biology and sequencing technology have propelled medical genetics forward, making it an essential component of modern medicine. (paramedicalcourses.co.in)
  • That's a very good question that isn't easily answered because the World Health Organization has defined many different subtypes of acute myeloid leukemia based on the cytogenetics and molecular genetics that are found in each patient. (targetedonc.com)
  • For the purposes of the community oncologist though, how the WHO classifies acute myeloid leukemia-except in 1 particular situation, which I'll talk about in a second-isn't particularly important when it comes to choosing the right treatment for the patient because the right treatment is going to be based on potentially cytogenetics and molecular genetics that aren't necessarily carved out as a specific subcategory. (targetedonc.com)
  • The photostability and narrow emission spectra of nanometer-scale semiconductor crystallites (QDs) make them desirable candidates for whole-mount fluorescent in situ hybridization to detect mRNA transcripts in morphologically preserved intact embryos. (hindawi.com)
  • To overcome permeability issues and allow QD conjugate penetration, embryos were treated with proteinase K. The use of QDs dramatically increased sensitivity of whole-mount in situ hybridization (WISH) in comparison with organic fluorophores and enabled fluorescent detection of specific transcripts within cells without the use of enzymatic amplification. (hindawi.com)
  • Molecular characterization of Novel ATM fusions in chronic lymphocytic leukemia and T-cell prolymphocytic leukemia. (cdc.gov)
  • We discuss the importance of molecular cytogenetic characterization of structural rearrangements to assist in genetic counseling related to the possible use of assisted reproductive technology. (canceropole-est.org)
  • The molecular characterization of these hybrids was refined using 74 sequence-tagged sites (STSs), which allowed the physical dissection of chromosome 5 into 71 distinct regions with an average length of 2.7 Mb. (uniba.it)
  • Peripheral blood lymphocytes were used for cytogenetic and fluorescence in situ hybridization analyses. (nih.gov)
  • recommended that a new phylogenetic analysis has to be done, with special careful attention to both morphological and molecular analyses with a broad taxonomic representation. (pensoft.net)
  • Detailed cytogenetic analyses of these cryobanked samples are therefore not possible. (journaltocs.ac.uk)
  • This work therefore enables: (i) a comparison of the P. coriacea karyotype with that of the critically endangered P. corroboree and (ii) a benchmark for repeat and future cytogenetic and genomic analyses of cryostored samples of this genus. (journaltocs.ac.uk)
  • conserved genes, whole chromosomes, or whole genomes) used in hybridization studies in order to identify microorganisms, to measure DNA-DNA homologies, to group subspecies, etc. (curehunter.com)
  • The concept that proto-oncogenes or tumor suppressor genes are involved in the various forms of microscopically discernible aberrant chromosomes has been fully supported by the numerous molecular studies that have defined many such tumor-specific changes. (nih.gov)
  • Knowledge of the latest cytogenetic technologies will facilitate diagnosis and counseling related to genetic abnormalities such as inherited disorders, mental retardation, developmental delay, and autism. (medscape.com)
  • Cytogenetic analysis: Examining chromosomes under a microscope to identify structural or numerical abnormalities. (paramedicalcourses.co.in)
  • This is usually performed by a combination of gross (i.e., macroscopic) and histologic (i.e., microscopic) examination of the tissue, and may involve evaluations of molecular properties of the tissue by immunohistochemistry or other laboratory tests Cytogenetics The Cytogenetics Lab offers karyotype analysis and SNP-microarray analysis to detect balanced, unbalanced, and copy number neutral chromosome abnormalities at the whole genome level. (metropolisindia.com)
  • That's a broad list of cytogenetic and molecular genetic abnormalities that classify patients into different groups. (targetedonc.com)
  • Due to its numerous advantages over conventional cytogenetic analysis techniques, Multiplex Ligation-dependent Probe Amplification could be used in the near future as the main technique for the molecular investigation of genetic conditions caused by copy number variations, in both rare and complex genetic disorders. (rrml.ro)
  • Array comparative genomic hybridization (aCGH) allows CGH to be performed without cell culture and isolation. (wikipedia.org)
  • During whole genome microarray-based comparative genomic hybridisation (array CGH) screening of subjects with idiopathic intellectual disability, we identified two unrelated individuals with a similar de novo interstitial microdeletion at 2p15-2p16.1. (bmj.com)
  • Array-based comparative genomic hybridization (array-CGH) was performed on 25 samples with microdeletions. (ufrgs.br)
  • Multiplex Ligation-dependent Probe Amplification is a technique proposed for the detection of deletions or duplications that may lead to copy number variations in genomic DNA, mainly due to its higher resolution, and shorter overall diagnosis time, when compared with techniques traditionally used, namely karyotyping, fluorescence in situ hybridization, and array comparative genomic hybridization. (rrml.ro)
  • Fluorescence in situ hybridizations using rDNA and the telomeric TTAGG sequence as probes have been carried out. (pensoft.net)
  • Methods based on using region-specific chromosome 21 DNA probes and fluorescence in situ hybridization show promise for the rapid diagnosis of trisomy 21 (Lichter et al. (curehunter.com)
  • Probes and targets are finally visualized in situ by microscopy analysis. (biosyn.com)
  • The use of centromeric probes revealed significant hidden high hyperdiploidy of 33% and 59%, respectively, in patients with normal (n = 21/64) or failed (n = 32/54) cytogenetic results. (birmingham.ac.uk)
  • This technique, known as whole mount in situ hybridization (WISH) , was initially performed using radioactive probes, but was radically simplified when nonradioactive probes were used successfully [ 2 - 4 ]. (hindawi.com)
  • This ap-proach could probably be useful for interphase molecular-cytogenetic analysis. (edu.mk)
  • Patients with genetic disorders require specific types of cytogenetic testing for accurate diagnosis and prognosis followed by prompt treatment. (medscape.com)
  • Dr Carraway, let's get a little into the weeds about the types of cytogenetic and molecular genetic alterations seen in patients with acute myeloid leukemia. (targetedonc.com)
  • Cytogenetic Heterogeneity in Chronic Lymphocytic Leukemia. (cdc.gov)
  • Molecular map of chronic lymphocytic leukemia and its impact on outcome. (cdc.gov)
  • Prognostic and Predictive Molecular Biomarkers in Chronic Lymphocytic Leukemia. (cdc.gov)
  • Here, a prevalence of skew-ed X-inactivation in RTT girls with homologous highly heteromorphic X chromosomes and preferential inactiva-tion of the maternal chromosome, were detected by a molecular-cytogenetic approach, and confirmed by the PCR-based technique (seven out of eight girls). (edu.mk)
  • Your doctor will perform a molecular analysis on your cells to identify specific genetic changes. (schoolandyouth.org)
  • Figure 1: Molecular analysis of the WDLPS neochromosome. (sarcomahelp.org)
  • 16. Wong MS, Lam ST. Cytogenetic analysis of patients with primary and secondary amenorrhoea in Hong Kong: retrospective study. (rbmb.net)
  • Therefore, molecular-cytogenetic assay using metaphase chromo-somes of individuals with heteromorphic chromosome X could be applied for X-inactivation analysis. (edu.mk)
  • With the advent of cell type specific molecular markers, description and analysis of developmental morphogenesis has become possible in a number of biological systems. (hindawi.com)
  • Vachaita mimwe miedzo yakadai se immunophenotyping, cytogenetic analysis uye / kana zvidzidzo zvema molecular kuti vawane mamwe mashoko ekuratidza kuti lymphoma inogona kuita sei. (lymphoma.org.au)
  • Chii chinonzi cytogenetic analysis? (lymphoma.org.au)
  • Magsasagawa sila ng mga karagdagang pagsusuri tulad ng immunophenotyping, cytogenetic analysis at/o molecular studies upang malaman ang higit pang impormasyon upang ipahiwatig kung paano maaaring kumilos ang lymphoma. (lymphoma.org.au)
  • The results from these studies play important roles in cytogenetic diagnosis, prognosis, and guide treatment of specific types of hematologic malignancies and solid tumors. (metropolisindia.com)
  • Abstract 195: Molecular mechanisms that activate convergent oncogenic pathway in genomically complex angiosarcoma Cancer Research . (academictree.org)
  • The aim was to identify cellular and cytogenetic markers of prognostic relevance to survival of high-risk MDS cases. (who.int)
  • In addition, cytogenetic testing is done on solid tumors, such as renal cell carcinoma, testicular tumors, and liposarcomas. (meditest.co.in)
  • Postnatal molecular cytogenetic tests target common microdeletion syndromes such as Prader-Willi syndrome, DiGeorge syndrome, and Williams syndrome. (meditest.co.in)
  • The treating clinician or pathologist may use cryopreserved cells or nucleic acid, nondecalcified formalin fixed paraffin-embedded (FFPE) tissue, or unstained marrow aspirate or PB specimens obtained and prepared from PB, BM aspirate, or other involved tissues for molecular or genetic studies in which the use of such material has been validated. (medscape.com)
  • For patients who present with extramedullary disease without BM or blood involvement, a tissue biopsy should be evaluated and processed for morphologic, immunophenotypic, cytogenetic, and molecular genetic studies, as recommended for the BM. (medscape.com)
  • 13. Rajangam S, Nanjappa L. Cytogenetic studies in amenorrhea. (rbmb.net)
  • While epidemiological findings contribute to the scientific literature on radiation carcinogenesis, particularly risk assessments, conclusions regarding ionizing radiation as a cause of human cancer are based upon a synthesis of evidence from molecular and cytogenetic research, experimental studies in radiobiology, epidemiology, and theoretical work on cancer causation. (cdc.gov)
  • In recent years, the application of genetic molecular methods introduced advances in the diagnosis and typification of the cri-du-chat syndrome. (medscape.com)
  • Samples from five Fragile X syndrome patients, diagnosed using cytogenetic and molecular methods, as well as from their parents and five controls were included in the study. (genome-integrity.org)
  • this allows hybridization to occur once two samples are mixed. (wikipedia.org)
  • Most of the cases (approximately 80%) are due to a de novo deletion, a little more than 10% of the cases are originated by a parental translocation, and less than 10% are associated with cytogenetic rare aberrations. (medscape.com)
  • [ 1 , 2 ] At the molecular level, this particular translocation results in the fusion of the BCR gene on chromosome 22 to the ABL gene on chromosome 9. (medscape.com)
  • Today, the study of molecular cytogenetics can be useful in diagnosing and treating various malignancies such as hematological malignancies, brain tumors, and other precursors of cancer. (wikipedia.org)
  • Although cytogenetic and molecular genetic findings have been reported extensively for RMS, clinicopathologic-genetic correlations among these tumors have not been reported in detail. (lookfordiagnosis.com)
  • 4. Kara N, Tural S, Elbistan M, Karakus N, Guven D, Kocak I. Cytogenetic findings of patients with Amenorrhea in Turkish population: A retrospective study. (rbmb.net)
  • . In situ hybridization (ISH) is a quite common technique among developmental research labs, yet its uses are quite diverse and include medical and prenatal diagnostics [ 9 - 16 ]. (hindawi.com)
  • See the LLS fact sheet, Cancer Molecular Profiling for more information. (schoolandyouth.org)
  • However, a lack of consistent coverage and payment rules for developing genomic procedures could impede molecular cytogenetics in cancer and individualized therapy. (marketdataforecast.com)
  • Center for Translational Research and Molecular Biology of Cancer, Maria Skłodowskaj-Curie Institute-Oncology Center, Gliwice Branch, ul. (mdpi.com)
  • Investigating biochemical processes right down to the molecular level has brought about huge leaps in our understanding across many disciplines, from evolution and reproduction to disease prevention and engineering. (hud.ac.uk)
  • Most mediastinal GCTs in adolescents and young adults occur in males, and 22% to 50% have cytogenetic changes consistent with Klinefelter syndrome. (kaiserpermanente.org)
  • RÉSUMÉ La présente étude a examiné les cellules souches hématopoïétiques de 19 cas de syndrome myélodysplasique de haut risque à la recherche de signaux apoptotiques et anti-apoptotiques et de proliférations cellulaires et a établi un lien entre ces derniers et les sous-types cytogénétiques et cliniques, en particulier la trisomie 8. (who.int)
  • Les cas de syndrome myélodysplasique de haut risque avaient un pourcentage nettement supérieur de cellules CD34+ apoptotiques et de survivine+ anti-apoptotiques par rapport aux témoins, en particulier dans les cas atteints de trisomie 8. (who.int)
  • One of the other key factors propelling the market for Molecular Cytogenetics is the capacity to scan and analyze the entire genomic organization. (marketdataforecast.com)
  • Can the disease process be related to a molecular defect such as a defect in an enzyme pathway, structural protein, or molecular receptor? (vin.com)
  • Partial cystectomy is for highly selected patients with a single tumor at a single point in time in a surgically amenable location who have no associated carcinoma in situ (CIS) and a bladder volume capable of tolerating a partial resection. (medscape.com)
  • 3. Soltani N, Mirzaei F, Ayatollahi H. Cytogenetic Study of Patients with Primary Amenorrhea in the Northeast of Iran. (rbmb.net)
  • This molecular cytogenetic study could be helpful in the future for solving the problem of distinctiveness of both genera. (pensoft.net)
  • The present study revealed that cytogenetic study is essential for early diagnosis and treatments of Amenorrhea. (rbmb.net)
  • 15. Roy AK, Banerjee D. Cytogenetic study of primary amenorrhoea. (rbmb.net)
  • Innovations in cytogenetic techniques and diagnostic capabilities have enabled earlier detection and diagnosis of genetic disorders. (medscape.com)
  • This primer will serve as a guide for pediatric nurse practitioners on the use of various cytogenetic testing for the diagnosis of genetic disorders. (medscape.com)
  • In summary, CLL is similar to other hematological malignancies whose pathogenesis involves mutational changes at the molecular level that ultimately lead to malignant transformation of a cell (Irons and Stillman 1996). (cdc.gov)
  • The partial chromosome paints generated from these hybrids will make powerful tools for cytogenetic investigations, especially on the cytogenetic evolution of primates, and examples are reported. (uniba.it)