Checkpoint Kinase 2Cell Cycle ProteinsGenes, cdcDNA DamageMitosisG2 PhaseCell CycleM Phase Cell Cycle CheckpointsHydroxyureaS PhaseProtein-Serine-Threonine KinasesProtein KinasesSchizosaccharomycesAtaxia Telangiectasia Mutated ProteinsCell Cycle CheckpointsSpindle ApparatusSchizosaccharomyces pombe ProteinsDNA ReplicationNuclear ProteinsKinetochoresDNA-Binding ProteinsDNA RepairMutationSaccharomyces cerevisiae Proteinscdc25 PhosphatasesG1 PhaseFungal ProteinsCDC2 Protein KinasePhosphorylationMolecular Sequence DataNocodazoleGamma RaysChromosome SegregationTumor Suppressor Protein p53G2 Phase Cell Cycle CheckpointsChromosomal InstabilitySaccharomyces cerevisiaeRadiation, IonizingCyclin BAnaphaseTumor Suppressor ProteinsMad2 ProteinsS Phase Cell Cycle CheckpointsHeLa CellsRepressor ProteinsDNA, FungalSignal TransductionAmino Acid SequenceUltraviolet RaysCyclinsNucleic Acid Synthesis InhibitorsExonucleasesBase SequenceBRCA1 Protein14-3-3 ProteinsGenes, FungalMeiosisRadiation ToleranceCdc20 ProteinsProtein BindingCell LineDNA Breaks, Double-StrandedAtaxia TelangiectasiaCell NucleusChromosomesHistonesChromatinGene Expression Regulation, FungalCarrier ProteinsTranscription FactorsModels, BiologicalTranscription, GeneticGene DeletionDose-Response Relationship, RadiationSequence Homology, Amino AcidIntracellular Signaling Peptides and ProteinsCell DivisionCalcium-Binding ProteinsRNA, Small InterferingCell Line, TumorCyclin-Dependent Kinase Inhibitor p21DNAGene Expression RegulationRNA InterferenceCaffeineCyclin-Dependent KinasesPhenotypeApoptosisMicrotubulesProtein Structure, TertiaryDNA Repair EnzymesMetaphaseMutagenesisGenomic InstabilityGene Expression ProfilingAnaphase-Promoting Complex-CyclosomeUbiquitin-Protein Ligase ComplexesAurora KinasesTime FactorsMethyl Methanesulfonate