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  • Biology
  • C. crescentus , an alpha-proteobacterium that inhabits freshwater, seawater and soils, is an ideal organism for genetic and computational biology studies due to the wealth of molecular information that has been accumulated by researchers. (eurekalert.org)
  • The article "Temporal controls of the asymmetric cell division cycle in Caulobacter crescentus" is by Genetics, Bioinformatics, and Computational Biology graduate student Shenghua Li, research scientist Paul Brazhnik, Professor and Director of VBI's Cyberinfrastructure Group Bruno Sobral, and University Distinguished Professor of Biological Sciences John Tyson. (eurekalert.org)
  • dynamics
  • The mathematical model described in the paper allows researchers to study and analyze the systems-level dynamics of the Caulobacter cell cycle, test hypotheses and suggest crucial new experiments. (eurekalert.org)
  • mutations
  • Taking this one step further, they were also able to simulate the impact of specific known mutations on cell function. (eurekalert.org)
  • normally
  • Caulobacter normally undergoes a cell cycle that produces two different types of offspring: a motile "swarmer cell" with a flagellum, a slender thread-like structure that allows the bacterium to swim, and an immobile "sessile stalked cell" that lacks a flagellum. (eurekalert.org)
  • scientists
  • However, prokaryotic cells like Caulobacter have been somewhat neglected as information systems in studies by scientists. (eurekalert.org)