We offer many different probe formats including BHQ and BHQplus probes, Molecular Beacons and Scorpions Primers. (biosearchtech.com)
Probes2
Molecular beacons, or molecular beacon probes, are oligonucleotide hybridization probes that can report the presence of specific nucleic acids in homogenous solutions. (wikipedia.org)
Next generation sequencing panel based on single molecule molecular inversion probes for detecting genetic variants in children with hypopituitarism. (umich.edu)
Quantification1
SNP detection Real-time nucleic acid detection Real-time PCR quantification Allelic discrimination and identification Multiplex PCR assays Diagnostic clinical assays Shekdar K, Langer J, Venkatachalan S, Schmid L, Anobile J, Shah P, et al. (wikipedia.org)
Discrimination2
rhAmp Genotyping Master Mix and rhAmp Reporter mixes are specially formulated for use with rhAmp SNP Assays to deliver enhanced allelic discrimination and signal generation. (idtdna.com)
The rhAmp SNP Genotyping System offers enhanced allelic discrimination versus traditional methods. (idtdna.com)
Assay1
The results were compared with those obtained by the molecular method, line probe assay GenoType Mycobacterium CM/AS/NTM-DR. All samples were concordantly identified by MALDI-TOF MS and the molecular test for all the tested mycobacteria. (bvsalud.org)
Probe1
A typical molecular beacon probe is 25 nucleotides long. (wikipedia.org)
Variants2
Allelic Variants in Established Hypopituitarism Genes Expand Our Knowledge of the Phenotypic Spectrum. (umich.edu)
2013. Differential representation of B cell subsets in mixed bone marrow chimera mice due to expression of allelic variants of CD45 (CD45.1/CD45.2). (versiti.org)
Moving from early studies exploring the genetic bases of individual predisposition to severe toxicities from chemotherapy agents [i.e. 5-fluorouracil (5-FU) or irinotecan] in mCRC patients, the introduction of targeted agents such as anti-epidermal growth factor receptor (EGFR) drugs, has prompted the discovery of predictive molecular biomarkers (i.e. (oaepublish.com)
Detection1
That cleverly avoided the using of complex instruments and offered a visual detection of the molecular binding events under an ordinary experiment conditions [15]. (biomedres.us)
Complex2
Xpert MTB/RIF Ultra (Xpert Ultra), a molecular test that can simultaneously identify M. tuberculosis complex and resistance to rifampicin directly on clinical samples, is currently used. (bvsalud.org)
The growing knowledge of CRC molecular characteristics and complex genomic makeup has played a crucial role in identifying predictive pharmacogenomic biomarkers, while supporting the rationale for the development of new drugs and treatment combinations. (oaepublish.com)
Article1
L'équipe Beagle, représentée par Vincent Liard, David Parsons, Jonathan Rouzaud-Cornabas et Guillaume Beslon s'est vue décerner le prix du meilleur article lors de la conférence internationale ALife 2018 (International Conference on Artificial Life) en Juillet 2018 à Tokyo pour leurs travaux sur l'évolution de la complexité. (cnrs.fr)
Target2
Molecular beacons are hairpin-shaped molecules with an internally quenched fluorophore whose fluorescence is restored when they bind to a target nucleic acid sequence. (wikipedia.org)
Over time, additional mechanisms of primary and secondary resistance to targeted agents have emerged as promising novel predictive biomarkers and potentially actionable target of treatment, although validation is still an issue in most cases, and many steps forward have been made in the biological understanding and molecular characterization of CRC [ 6 ] . (oaepublish.com)
Results1
When the beacon is in closed loop shape, the quencher resides in proximity to the fluorophore, which results in quenching the fluorescent emission of the latter. (wikipedia.org)
Made1
The need to understand the molecular mechanisms in species has made the PCR an indispensable tool for understanding the functioning of these biological systems. (intechopen.com)