However, the exact mechanisms, primary modes of action, and its true clinical effects remain to be delineated and verified. (hho-bulgaria.com)
Exploring highly expressed pathways in stromal components, such as fibroblasts, will delineate the underlying mechanisms that are pivotal for tumor microenvironment maintenance. (biomedcentral.com)
Highly2
Therefore, accurate analysis of a broad spectrum of biomarkers is highly recommended to delineate the correlation between clinical and biochemical presentations and the proposed biological effect of H 2 . (hho-bulgaria.com)
This valuable study reports multi-scale molecular dynamics simulations to investigate a class of highly potent antibodies that simultaneously engage with the HIV-1 Envelope trimer and the viral membrane. (elifesciences.org)
Study3
In this study, a proton nuclear magnetic resonance ( 1 H NMR)-based metabolomics approach was applied in conjunction with multivariate statistical analysis to investigate the altered metabolic profiles in blood serum and urine samples obtained from HAE patients. (biomedcentral.com)
The altered Fischer ratio, together with perturbations in metabolic pathways identified in the present study, may provide new insights into the mechanistic understanding of HAE pathogenesis and potential therapeutic interventions. (biomedcentral.com)
Though a growing body of literature is addressing the possible longer-term cognitive effects of anesthetics, to date no study has delineated the normal trajectory of neural recovery due to anesthesia alone in older adults. (biorxiv.org)
General1
Such a mechanistic understanding of neural recovery from general anesthesia is vital to understanding the role, if any, of anesthetic agents in the pathogenesis of Perioperative Neurocognitive Disorders (PND) 9 - 13 . (biorxiv.org)