Modulation proteins glucose transporter type 2. Medical search. Frequent questions

Cocoa flavonoids attenuate high glucose-induced insulin signalling blockade and modulate glucose uptake and production in human HepG2 cells. (voedingsgeneeskunde.nl)
insulin resistance state affecting GLUT4 translocation which is important in affecting glucose uptake. (sciencebiology.org)
Stimulation of GLUT4 Glucose Uptake by Anthocyanin-Rich Extract from Black Rice (Oryza sativa L.) via PI3K/Akt and AMPK/p38 MAPK Signaling in C2C12 Cells. (sciencebiology.org)
Mulberry Leaf Extract Stimulates Glucose Uptake and GLUT4 Translocation in Rat Adipocytes. (sciencebiology.org)
Portulaca oleracea L. Extract Enhances Glucose Uptake by Stimulating GLUT4 Translocation to the Plasma Membrane in 3T3-L1 Adipocytes. (sciencebiology.org)
This activation is necessary for both cell proliferation as well as glucose uptake and use. (hindawi.com)
This observation resulted in the development of 2-[18F]-fluoro-2-deoxy-D-glucose positron emission tomography (PET) to detect glucose uptake and lactate production for tumor imaging. (hindawi.com)
Cellular growth and glucose uptake are regulated by multiple signals generated by the insulin receptor. (cnr.it)
We investigated the role of CaMKII in insulin signalling in a rat skeletal muscle cell line, demonstrating that CaMKII modulates the insulin action on DNA synthesis and the negative feedback that down regulates glucose uptake. (cnr.it)
Insulin stimulation generated partly independent signals leading to the rapid activation of Akt, Erk-1/2 and CaMKII Akt activation was followed by Glut-4 translocation to the plasma membrane and increase of glucose uptake. (cnr.it)
Then, IRS-1 was phosphorylated at S612, the IRS-1/p85PI3K complex was disrupted, Akt was no more phosphorylated and both Glut-4 translocation and glucose uptake were reduced. (cnr.it)
Inhibition of CaMKII also abrogated the down-regulation of insulin-stimulated Akt phosphorylation, Glut-4 membrane translocation and glucose uptake. (cnr.it)
2 - after the initial stimulation of the IRS-1/Akt pathway, CaMKII mediates the down-regulation of stimulated glucose uptake. (cnr.it)
S. H. Kim and coworkers (" Citrus junos Tanaka peel extract exerts antidiabetic effects via AMPK and PPAR- both in vitro and in vivo in mice fed a high-fat diet ") indicate that the ethanol extract of the peel of Citrus junos in vitro stimulates glucose uptake in C2C12 myotube cells. (hindawi.com)
Since the mid-1960s, it has been known that there are energy-dependent, sodium-coupled glucose transporter (SGLT) and energy-independent, facilitative glucose transporter (GLUT) pathways for glucose uptake in the lung [ 1 ], and that glucose can permeate the alveolar epithelial barrier [ 2 ]. (ersjournals.com)
Glucose removal is determined by cellular glucose uptake and metabolism ( fig. 1 ) [ 4 , 12 - 14 ]. (ersjournals.com)
TLK16998 also increased the potency of insulin in stimulating 2-deoxy- d -glucose uptake in 3T3-L1 adipocytes, with a detectable effect at 8 μmol/l and a 10-fold increase at 40 μmol/l. (diabetesjournals.org)
In contrast, only small effects were observed on IGF-1-stimulated 2-deoxy- d -glucose uptake. (diabetesjournals.org)
Polyphenols and phenolic acids from strawberry and apple may decrease glucose uptake by blocking transport through human intestinal cells, according to a new study. (nutraingredients.com)
"There is recent evidence that some bioactive compounds, in particular polyphenols, phenolic acids and tannins (PPTs), can affect the shape of the blood glucose curve … Some studies have shown that these compounds may result in an altered pattern of intestinal glucose uptake, possibly due to interactions between compounds and sugar transporters," said the authors. (nutraingredients.com)
"The results obtained demonstrate that polyphenols, phenolic acids and tannin-rich extracts from strawberry and apple were able to influence glucose uptake into the cells and transport … by inhibiting activities of the glucose transporters," said the authors. (nutraingredients.com)
These agents improve peripheral glucose uptake and utilization. (medscape.com)

In addition to its role in glucose metabolism, this pathway also regulates the redirection of free amino acids to protein synthesis via the mTOR-signaling pathway. (hindawi.com)
In contrast to normal cells, most cancer cells predominantly produce energy by a high rate of glycolysis followed by lactate fermentation, even in the presence of oxygen, a less efficient metabolism compared to a low rate of glycolysis followed by mitochondrial oxidation of pyruvate [ 2 ]. (hindawi.com)
We conclude that the global absence of B1R impairs catecholamine synthesis, interfering with glucose metabolism at rest and during maximal exercise. (bvsalud.org)
SIGNIFICANCE: B1R has an important role in the hepatic glucose metabolism, which in turn influences the energetic metabolism, and in long-term outcomes, such as in the decrease in hepatic glycogen stores and in the enhancement of hepatic metabolism. (bvsalud.org)
Many proteins are enzymes that catalyze the chemical reactions in metabolism. (wikipedia.org)
Amino acids also contribute to cellular energy metabolism by providing a carbon source for entry into the citric acid cycle (tricarboxylic acid cycle), especially when a primary source of energy, such as glucose, is scarce, or when cells undergo metabolic stress. (wikipedia.org)
Halothane metabolism: immunochemical evidence for molecular mimicry of trifluoroacetylated liver protein adducts by constitutive polypeptides. (aspetjournals.org)
Glucose is removed from ASL in proximal airways via facilitative glucose transporters, down a concentration gradient generated by intracellular glucose metabolism. (ersjournals.com)
Accumulated evidence from genetic animal models suggests that the brain, particularly the hypothalamus, has a key role in the homeostatic regulation of energy and glucose metabolism. (nature.com)
The brain modulates various aspects of metabolism, such as food intake, energy expenditure, insulin secretion, hepatic glucose production and glucose/fatty acid metabolism in adipose tissue and skeletal muscle. (nature.com)
Here we comprehensively review the above topics, discussing the main findings related to the role of the brain in the homeostatic regulation of energy and glucose metabolism. (nature.com)
The aim of this review was to summarize and discuss current knowledge on the impact of dietary fibre as modulator of the relationship between glucose metabolism and microbiota composition in humans. (springer.com)
More specifically, we analysed evidence from observational studies and randomized nutritional intervention investigating the relationship between gut microbiota, short-chain fatty acids and glucose metabolism. (springer.com)
Indeed, it may influence multiple physiological mechanisms related to human health, i.e. synthesis of micronutrients, defence against pathogens, regulation of glucose and lipid metabolism, and immune function [ 1 ]. (springer.com)
Therefore, in this review, we summarized current evidence from observational and intervention studies performed in humans investigating the relationship between the composition of the gut microbiota, concentration of SCFA and glucose metabolism. (springer.com)
We hypothesized that changes in cardiac macrophage glucose metabolism would reflect polarization status after myocardial infarction (MI), ranging from the early inflammatory phase to the later wound healing phase. (biomed.news)

Jiao H, Hu G, Gu D, Ni X. Having a promising efficacy on type II diabetes, it's definitely a green tea time. (voedingsgeneeskunde.nl)
Zunino S. Type 2 diabetes and glycemic response to grapes or grape products. (voedingsgeneeskunde.nl)
Overview of clinically approved oral antidiabetic agents for the treatment of type 2 diabetes mellitus. (sciencebiology.org)
cell failure in type 2 diabetes. (sciencebiology.org)
2021). Pedoman Pengelolaan Dan Pencegahan Diabetes Melitus Tipe 2 Dewasa Di Indonesia. (sciencebiology.org)
In type 2 diabetes, receptor activation and recognition by microorganisms from the intestinal lumen may trigger inflammatory responses, inducing the phosphorylation of serine residues in insulin receptor substrate-1, reducing insulin sensitivity. (biomedcentral.com)
In type 1 diabetes, the lowered expression of adhesion proteins within the intestinal epithelium favours a greater immune response that may result in destruction of pancreatic β cells by CD8+ T-lymphocytes, and increased expression of interleukin-17, related to autoimmunity. (biomedcentral.com)
Research in animal models and humans has hypothesized whether the administration of probiotics may improve the prognosis of diabetes through modulation of gut microbiota. (biomedcentral.com)
Scientific evidence suggests increased inflammatory stress is related to molecular mechanisms leading to insulin resistance, and the intestinal microbiota interacts with environmental factors and susceptible genetic factors, contributing to the development of diabetes [ 2 ]. (biomedcentral.com)
Our aim is to clarify the currently described effects of probiotics in the prevention and management of type 1 (T1D) and type 2 (T2D) diabetes mellitus. (biomedcentral.com)
Obesity can be viewed as a state of long-term lipid disequilibrium that is marked by massive adipocyte hypertrophy and is a major risk factor for developing insulin resistance and type 2 diabetes. (jci.org)
However, much subsequent research in this area was focused on the role of pulmonary SGLT transport as a modifier of lung liquid volume [ 3 , 4 ], and the effects of starvation and diabetes on glucose transport [ 1 , 5 ]. (ersjournals.com)
Conversely, reactive oxygen species may favor the development of type 2 diabetes mellitus, mainly through the induction of insulin resistance. (biomedcentral.com)
Defective crosstalk between the brain and peripheral organs contributes to the development of obesity and type 2 diabetes. (nature.com)
On the other hand, several studies suggested that diet might influence gut microbiota composition and activity thus modulating the risk of metabolic disease, i.e. obesity, insulin resistance and type 2 diabetes. (springer.com)
In particular, animal studies support a causal role between the composition of the gut microbiota and development of obesity, insulin resistance and type 2 diabetes (T2D). (springer.com)
In diabetes, more fat and less carbohydrate is used, due to the reduced induction of GLUT4 glucose transporters to the cell surfaces. (wikidoc.org)
It is well established that PP cows often exhibit symptoms similar to type 2 diabetes (T2DM), including elevated plasma free fatty acid concentrations and decreased sensitivity of tissue to the presence of insulin which plays a major role in the development of many metabolic disorders [ 10 ]. (biomedcentral.com)
Canagliflozin, a type 2 diabetes drug, is a sodium glucose co-transporter 2 (SGLT2) inhibitor with known off-target effects on glutamate dehydrogenase and complex I. However, the effects of SGLT2 inhibitors on human T cell function have not been extensively explored. (biomed.news)
Insulin resistance, an important feature of type 2 diabetes, is manifested as attenuated insulin receptor (IR) signaling in response to insulin binding. (diabetesjournals.org)
A drug that promotes the initiation of IR signaling by enhancing IR autophosphorylation should, therefore, be useful for treating type 2 diabetes. (diabetesjournals.org)
These results suggest, therefore, that small nonpeptide molecules that directly sensitize the IR may be useful for treating type 2 diabetes. (diabetesjournals.org)
It is estimated that diabetes affects 6% of the population in the U.S. and 3% of the population in northern Europe, with type 2 diabetes representing 90% of the cases ( 1 ). (diabetesjournals.org)
Two metabolic defects that seem to be central to the pathology of type 2 diabetes are impaired insulin secretion and the reduced ability of insulin to act on the major insulin-sensitive tissues ( 2 - 5 ). (diabetesjournals.org)
Repeated high post meal (post-prandial) blood plasma glucose 'spikes' are associated with an increased risk of developing cardiovascular diseases, metabolic syndrome and type II diabetes. (nutraingredients.com)

Our group has shown in several papers that kinin B1 receptor (B1R) is involved in metabolic adaptations, mediating glucose homeostasis and interfering in leptin and insulin signaling. (bvsalud.org)
Highly coordinated interactions between the brain and peripheral metabolic organs are critical for the maintenance of energy and glucose homeostasis. (nature.com)
Therefore, it has been suggested that the modulation of gut microbiota could be a reliable tool to prevent metabolic and inflammatory diseases. (springer.com)
Within this context, the prebiotic effect of dietary fibres might be a feasible strategy to prevent T2D, through the modulation of metabolic response. (springer.com)
Compromised c-Myc levels were encapsulated by a failure to engage translational machinery resulting in impaired metabolic protein and solute carrier production among others. (biomed.news)
Modulation of metabolic flux through pyruvate dehydrogenase complex (PDC) plays an important role in T cell activation and differentiation. (biomed.news)
The combination of these defects results in an inability of the body to maintain glucose homeostasis leading to hyperglycemia and other metabolic disturbances ( 2 ). (diabetesjournals.org)

Some research shows that plant extract proved to be potential in increasing the translocation of GLUT4 and helping lowering blood glucose levels. (sciencebiology.org)
Regulated transport of the glucose transporter GLUT4. (sciencebiology.org)
Evidence for defects in the trafficking and translocation of GLUT4 glucose transporters in skeletal muscle as a cause of human insulin resistance. (sciencebiology.org)
The GLUT4 Glucose Transporter. (sciencebiology.org)
Differentiation of erythrocyte-(GLUT1), liver-(GLUT2), and adipocyte-type (GLUT4) glucose transporters by binding of the inhibitory ligands cytochalasin B, forskolin, dipyridamole, and isobutylmethylxanthine. (aspetjournals.org)
However, contraction itself plays a part in bringing GLUT4 transporters to the surface [2] . (wikidoc.org)

The action of antidiabetic plants of the Canadian James Bay Cree traditional pharmacopeia on key enzymes of hepatic glucose homeostasis ") report the antidiabetic action of seven Canadian plants as evidenced by glucose-6-phosphatase and glycogen synthase, two key enzymes, respectively, involved in gluconeogenesis and glycogenesis in hepatocytes. (hindawi.com)
The adipocyte is the major site of fatty acid storage in the body and plays a critical role in maintaining normal glucose and lipid homeostasis. (jci.org)
Understanding of mechanisms underlying lung glucose homeostasis could identify new therapeutic targets for control of ASL glucose and prevention and treatment of lung infection. (ersjournals.com)

In diabetic mice, TLK16998, at a dose of 10 mg/kg, lowered blood glucose levels for up to 6 h. (diabetesjournals.org)
These agents stimulate insulin secretion from pancreatic cells, lowering blood glucose levels. (medscape.com)

All capillaries in the central nervous system with a functional blood-brain barrier express glucose transporters (GLUT1). (wikipedia.org)

This is in contrast to conditions in the gut and kidney, where luminal glucose concentrations regularly exceed plasma glucose concentrations [ 6 , 7 ]. (ersjournals.com)
0.01 mM and plasma glucose 0.19 mM [ 3 ]. (ersjournals.com)
On d 7 and 14 PP plasma glucose was higher in BBR2- and BBR4-treated than in CTRL. (biomedcentral.com)
Although all diabetic cells are exposed to elevated levels of plasma glucose, hyperglycemic damage is limited to those cell types that are unable to down regulate glucose transport into the cell (e.g., endothelial cells), leading to intra-cellular hyperglycemia ( Brownlee, 2001 ). (scialert.net)

Inhibition of CaMKII abrogated the insulin-induced Erk-1/2 activation, DNA synthesis and phosphorylation of IRS-1 at S612. (cnr.it)
This phenotype was related to alterations in adrenal catecholamine synthesis: increased basal epinephrine concentration and reduced norepinephrine content in response to exercise, as well decreased gene expression and protein content of tyrosine hydroxylase and decreased gene expression of dopamine beta hydroxylase and kinin B2 receptor. (bvsalud.org)
or anabolic - the building up (synthesis) of compounds (such as proteins, carbohydrates, lipids, and nucleic acids). (wikipedia.org)
Protein stability was determined following treatment with protein synthesis inhibitor cycloheximide and proteasome inhibitor MG132. (thno.org)
The regulation of nutrient partitioning is arranged by complex interactions between hormones [i.e., insulin, growth hormone (GH), Insulin-like growth factor 1 (IGF-1), and glucocorticoids] aiming to favor glucose supply for milk synthesis that involves insulin action and the somatotropic axis [ 4 ]. (biomedcentral.com)

In normal cells, glucose participates in cellular energy production through glycolysis as well as through its complete catabolism via the tricarboxylic acid (TCA) cycle and oxidative phosphorylation (OXPHOS). (hindawi.com)
Selective activity and cellular pharmacology of (1R-1 alpha,2 beta,3 alpha)-9-[2,3-bis(hydroxymethyl)cyclobutyl]guanine in herpesvirus-infected cells. (aspetjournals.org)
When there is an overproduction of ROS/RNS or a deficiency of enzymatic or non-enzymatic antioxidants, a biological damage to cellular lipids (lipoperoxidation), proteins, glucides and DNA may occur. (biomedcentral.com)
One of the first consequences of oxygen and glucose deprivation during cerebral ischemia is membrane depolarization, the rapid depletion of cellular ATP, and the accumulation of extracellular excitatory amino acids. (jneurosci.org)

The mechanisms of individual modulation of these signals remain somewhat elusive. (cnr.it)
Mechanisms for the modulation of alkylating activity by the quinone group in quinone alkylating agents. (aspetjournals.org)
In this review we deal in the molecular mechanisms, the epigenetic effects and modulation of the oxidative stress pathway of ketogenic diets, that underlie its possible role, in the treatment of infantile gliomas, as a complementary approach to conventional cancer therapy. (frontiersin.org)
Our understanding of the role of glucose transport in the lung and the mechanisms that regulate glucose movement across the human lung epithelium lags far behind that of the gut and kidney. (ersjournals.com)
Current model of the mechanisms controlling glucose concentrations in the surface liquid lining the airway and distal lung epithelium. (ersjournals.com)

By stimulating the expression of glucose transporters and glycolytic enzymes, HIF-1 promotes glycolysis to generate more pyruvate [ 5 ]. (hindawi.com)

Here, we consider a newly identified role for pulmonary glucose transport in maintaining low airway surface liquid (ASL) glucose concentrations and propose that this contributes to lung defence against infection. (ersjournals.com)
These processes vary between species but universally maintain ASL glucose at 3-20-fold lower concentrations than plasma. (ersjournals.com)
ASL glucose concentrations are increased in respiratory disease and by hyperglycaemia. (ersjournals.com)
ASL glucose concentrations are the net result of diffusion of glucose from blood and interstitial fluid across the respiratory epithelium into the ASL, and removal of glucose from ASL by epithelial glucose transport processes. (ersjournals.com)
Physicians now recognize that zinc supplementation can reduce the incidence and severity of diarrheal disease, and an ORS of reduced osmolarity (i.e., proportionally reduced concentrations of sodium and glucose) has been developed for global use. (cdc.gov)
Activation of PPAR-gamma receptors regulates insulin-responsive gene transcription involved in glucose production, transport, and utilization, thereby reducing blood glucose concentrations and reducing hyperinsulinemia. (medscape.com)

In the distal lung, glucose transport via sodium-coupled glucose transporters predominates. (ersjournals.com)
They said that PPTs have the potential to "readily affect glucose absorption in the small intestine," noting that many polyphenols, phenolic acids and tannins can interact with certain sugar transporters - for example, inhibition of sodium-dependent glucose transporter 1 (SGLT1 - an active transport mechanism in which glucose is co-transported with sodium ion) or by inhibition of GLUT2. (nutraingredients.com)
By using sodium-containing (to activate both SGLT1 and GLUT2 glucose transporters) and sodium-free (activating GLUT2 only) conditions, the researchers showed that PPTs inhibit the action of GLUT2 receptors more than SGLT1. (nutraingredients.com)

Alternanthera sessilis red ethyl acetate fraction exhibits antidiabetic potential on obese type 2 diabetic rats ") report that, despite their inability to identify active compounds, they observed that ethyl acetate fraction of Alternanthera sessilis ameliorated T2D via increased insulin content and decreased insulin resistance. (hindawi.com)

We have shown in this review that a large body of evidence suggests probiotics reduce the inflammatory response and oxidative stress, as well as increase the expression of adhesion proteins within the intestinal epithelium, reducing intestinal permeability. (biomedcentral.com)
Modulation of intestinal microbiota by probiotics may facilitate the management of a number of clinical conditions [ 7 ]. (biomedcentral.com)
The research, published in Molecular Nutrition & Food Research , suggests that some polyphenols, phenolic acids and tannins extracted from apples and strawberries may block the transport of glucose across intestinal tissues, potentially blunting post-meal glucose spikes. (nutraingredients.com)
They added that their study is the first to show an inhibition of glucose transport across intestinal tissue by phenolic fruit extracts, and further characterize the contribution of individual phenolic components for their role in the inhibition of glucose transport. (nutraingredients.com)

One in vitro study by S.-C. Chang and W.-C. V. Yang titled " Hyperglycemia induces altered expressions of angiogenesis associated molecules in the trophoblast " describes the expression of perlecan and angiogenesis-related cytokines and growth factors in trophoblasts, one type of placenta cells. (hindawi.com)
We used an in vitro model of cerebral ischemia (oxygen-glucose deprivation) to examine changes in [Cl - ] i and GABA A receptor-mediated responses in hippocampal slices from adult rats. (jneurosci.org)
The accumulation of Na + and Ca 2+ during ischemia or oxygen-glucose deprivation (OGD), an in vitro model for transient global ischemia, has been investigated extensively. (jneurosci.org)

Medication for T2DM mainly focuses on lowering blood glucose and treating affected organs. (sciencebiology.org)

Open up in BGJ398 inhibition another window Body 2 Scatter plots evaluating immune system cell phenotypes between major tumor as well as the matching peritoneal lesion. (tech-strategy.org)
Therefore, the consumption of strawberry and apple juices could affect glucose absorption via the inhibition of glucose transport," said the researchers. (nutraingredients.com)

Taken together, post-endurance exercise protein intake may provide means to facilitate aerobic training adaptations. (biomedcentral.com)

These agents stimulate peripheral use of glucose as stimulated by insulin. (medscape.com)

Activator of protein kinase A (cyclic AMP agonist). (biolog.de)
Activation of a heart chloride current during stimulation of protein kinase C. (aspetjournals.org)
MSCs significantly reversed the imbalance of glycolysis in sperm and testis induced by testicular torsion-detorsion, as evidenced by increasing the expression of phosphoglycerate kinase 2 and glyceraldehyde-3-phosphate dehydrogenase-spermatogenic, activating Akt, and increasing glycogen synthase kinase 3 (GSK3), which led to the increase in glycolysis cascades and ATP production. (biomedcentral.com)

J. Wang and colleagues (" Improvement of liquid fructose-induced adipose tissue insulin resistance by ginger treatment in rats is associated with suppression of adipose macrophage-related proinflammatory cytokines ") show that treatment with ginger extract reduced fructose-induced insulin resistance in rats by suppression of adipose inflammatory cytokines (TNF- , IL-6, MPC-1, CCR-2, etc.) and increased phosphorylation of IRS-2. (hindawi.com)
The protective effect of B1R antagonism or deficiency was associated with increased levels of macrophage type 2 markers in the kidney. (bvsalud.org)

En los últimos años he compaginado mi labor investigadora con la actividad docente, y con labores de gestión: Subdirectora del Departamento de Farmacología, Universidad de Navarra (2009-12), Directora del Departamento de Farmacología y Toxicología, Universidad de Navarra (2012-2014) y Vicedecana (2014-2020) y Decana (2020- actualidad) de la Facultad de Farmacia y Nutrición, Universidad de Navarra. (unav.edu)

Samples are mixed with a cocktail of biotinylated detection antibodies (Step 1) and then incubated with the array membrane which is spotted in duplicate with capture antibodies to specific target proteins (Step 2) . (rndsystems.com)

Pancreatic ductal adenocarcinoma (PDAC) is characterized by a very dense and highly organized tumor microenvironment (TME) consisting of extracellular matrix (ECM) proteins, cancer-associated fibroblasts (CAFs), pancreatic stellate cells (PSCs), and immune cells. (mdpi.com)
A small flavone-type molecule, swertisin, found in Enicostemma littorale was tested for its ability to promote the generation of pancreatic islets. (hindawi.com)

The objective for this study was to determine the effect of berberine (BBR) during the peripartal period on hormonal alteration and somatotropic axis in dairy goats as well as glucose and insulin kinetics during an intravenous glucose tolerance test (IVGTT). (biomedcentral.com)

stream ATP-binding cassette transporters and HDL suppress hematopoietic stem cell proliferation. (skanestugan.se)

Tauopathies are a group of neurodegenerative diseases characterized by the hyperphosphorylation and deposition of tau proteins in the brain. (ibecbarcelona.eu)

It is only recently that we and others have begun to investigate glucose transport as an important mechanism for maintaining a nutrient-depleted environment in the lung lumen to limit the growth of pathogenic organisms. (ersjournals.com)

Accepted August 23, 2012 ABSTRACT The catabolite control protein CcpA is a pleiotropic regulator that mediates the global transcriptional response to rapidly catabolizable carbohydrates, like glucose in Gram-positive bacteria. (studyres.com)

Lactate export, glycolysis rate, and CD147 protein abundance were also inhibited by HSPA12A overexpression but promoted by HSPA12A knockdown. (thno.org)

As elucidated by Mulliken and Glowacki, these categories, representing the only two major types of vascular birthmarks, reflect differences in clinical, histologic, hematologic, and radiologic/skeletal features. (medscape.com)
North et al highlighted the presence of human glucose transporter 1 (GLUT-1) isoform as a useful differentiating factor between infantile hemangiomas and other vascular anomalies. (medscape.com)

Proteins are made of amino acids arranged in a linear chain joined by peptide bonds. (wikipedia.org)

Thus, after oxygen-glucose deprivation, diazepam may decrease neuronal excitability, thereby reducing the energy demands of the neuron. (jneurosci.org)

Mass spectrometry, immunoprecipitation, and immunoblotting were employed to examine protein-protein interactions. (thno.org)

The ependymal cells of the SCO are also involved in the production of brain transthyretin, a protein involved in the transport of thyroid hormones in blood. (wikipedia.org)
Glucose and glutamine are the 2 major substrates used by cancer cells. (hindawi.com)
High glucose affected the expression level of cell-bound perlecan, angiogenesis-associated cytokines, and the matrix degradation on the cells, implying that hyperglycemia influences vessel formation during placentation. (hindawi.com)
The highest density was observed for CD45+ cells, followed by CD3+ cells, CD8+ cells, and PD-1+ cells (Table 2). (tech-strategy.org)
Therefore, the mean count number in omental lesions of stromal CD8+ and CD3+ cells was almost 2 times higher. (tech-strategy.org)
Matters of (A) Compact disc3+, (B) Compact disc8+, and (C) PD-1+ (designed cell-death protein 1) stromal cells. (tech-strategy.org)
A) Matters of intratumoral PD-1+ (designed cell-death protein 1) cells have HDAC5 been around in tendencies higher in major tumor. (tech-strategy.org)
For over 50 years, glucose has been recognised to cross the lung epithelial barrier and be transported by lung epithelial cells. (ersjournals.com)
In immortalised human airway cells (line H441) with 10 mM glucose in the basolateral medium, apical ASL glucose was 0.24±0.07 mM [ 10 ]. (ersjournals.com)
In primary cultures of human bronchial epithelial cells (HBECs) with 16.6±0.4 mM glucose in the basolateral medium, ASL glucose was 2.2±0.5 mM [ 11 ]. (ersjournals.com)
Cells were passaged by a 5-min incubation with 0.5% trypsin/0.2% EDTA solution in phosphate-buffered saline (10 mM Na 2 HPO 4 , 150 mM NaCl, pH 7.3). (aspetjournals.org)
Astrocytes are a sub-type of glial cells in the central nervous system . (atozwiki.com)
many of these cells express the intermediate filament glial fibrillary acidic protein (GFAP). (atozwiki.com)
This type often has astrocytic endfoot processes that physically connect the cells to the outside of capillary walls when they are in proximity to them. (atozwiki.com)

In humans, a single astrocyte cell can interact with up to 2 million synapses at a time. (atozwiki.com)

Anatomy15

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