Cell ProliferationApoptosisCells, CulturedSignal TransductionCaspasesApoptosis Regulatory ProteinsCell Line, TumorCaspase 3Proto-Oncogene Proteins c-bcl-2Cell SurvivalInhibitor of Apoptosis ProteinsCell DivisionCell CycleIn Situ Nick-End LabelingCell LineDNA FragmentationTumor Cells, CulturedBlotting, Westernbcl-2-Associated X ProteinCell DifferentiationEnzyme ActivationRNA, MessengerFlow CytometryMice, Inbred C57BLX-Linked Inhibitor of Apoptosis ProteinTumor Suppressor Protein p53PhosphorylationDose-Response Relationship, DrugTransfectionDown-RegulationTime FactorsImmunohistochemistryRNA, Small InterferingReverse Transcriptase Polymerase Chain ReactionApoptosis Inducing FactorEnzyme InhibitorsCASP8 and FADD-Like Apoptosis Regulating ProteinCaspase 9Proto-Oncogene ProteinsCaspase InhibitorsMitochondriaGene Expression RegulationMice, KnockoutAntineoplastic AgentsUp-RegulationCaspase 8Fas Ligand ProteinGene Expression Regulation, Neoplasticbcl-X ProteinLymphocyte ActivationProto-Oncogene Proteins c-aktRats, Sprague-DawleyCell MovementGene ExpressionT-LymphocytesCytochromes cEpithelial CellsMice, TransgenicFibroblastsAnnexin A5Molecular Sequence DataBromodeoxyuridineRNA InterferenceTranscription FactorsReactive Oxygen SpeciesCell DeathModels, BiologicalTumor Necrosis Factor-alphaProtein-Serine-Threonine KinasesMice, NudeDNA-Binding ProteinsCysteine Proteinase InhibitorsMice, Inbred BALB CAmino Acid Chloromethyl KetonesProliferating Cell Nuclear AntigenPoly(ADP-ribose) PolymerasesMutationJurkat CellsNF-kappa BDisease Models, AnimalKi-67 AntigenMembrane GlycoproteinsRecombinant ProteinsNeoplasm ProteinsMitogen-Activated Protein KinasesNeuronsHL-60 CellsCarrier ProteinsMembrane ProteinsDrug SynergismProtein BindingCell Growth ProcessesStem CellsCyclin-Dependent Kinase Inhibitor p21Base SequencePhosphatidylinositol 3-KinasesCell CountCell Cycle ProteinsDNATNF-Related Apoptosis-Inducing Ligand